Diurnal rhythm in serum osteocalcin: relation with sleep, growth hormone, and PTH(1-84).

abstract：:To study the mechanism of action of thyroid hormones on bone, we examined the effects of immunosuppressive and nonimmunosuppressive cyclosporins, as well as of transforming growth factor beta 1 (TGF beta 1), 17 beta-estradiol (E2), and dihydroxytestosterone (DHT) on thyroxine (T4)- and triiodothyronine (T3)-stimulated...

journal_title：Calcified tissue international

authors： Lakatos P,Stern PH

更新日期：1992-02-01 00:00:00

abstract：:Plasma membrane vesicles were prepared from chicken osteoclasts, and active calcium transport was demonstrated in a spectrofluorimetric assay using the fluorescent calcium concentration indicator, fura-2. Transport activity was inhibited by quercetin (10 microM), sodium vanadate (10 microM), and the anticalmodulin age...

journal_title：Calcified tissue international

authors： Bekker PJ,Gay CV

更新日期：1992-10-01 00:00:00

abstract：:We have examined the effect of the anti-tumor compound taxol, on osteoclastic bone resorption. In the bone slice assay, taxol (0.1-0.001 microM) dose-dependently inhibited bone resorption with an IC50 of 0.08 microM. Osteoclast survival on bone slices was unaffected by 0.01-1 microM taxol, but 10 microM was cytotoxic....

journal_title：Calcified tissue international

authors： Hall TJ,Jeker H,Schaueblin M

更新日期：1995-12-01 00:00:00

abstract：:Sulfotransferase 1E1 (SULT1E1) catalyze estrogen into sulfate conjugation and is involved in the metabolism of phytoestrogen. A community-based cross-sectional study was conducted on 397 Korean women, to evaluate the association between genetic polymorphisms of SULT1E1 and bone mineral density (BMD) and the combined e...

journal_title：Calcified tissue international

authors： Lee SA,Choi JY,Shin CS,Hong YC,Chung H,Kang D

更新日期：2006-09-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) is commonly used in the assessment of the musculoskeletal system and associated pathology. The ability of MRI to measure the signals from water and lipid protons enables quantitative measurements of bone porosity. The goal of this investigation was to demonstrate that the density and c...

journal_title：Calcified tissue international

authors： Hong J,Hipp JA,Mulkern RV,Jaramillo D,Snyder BD

更新日期：2000-01-01 00:00:00

abstract：:Familial hypocalciuric hypercalcemia (FHH) is often considered in the differential diagnosis of hyperparathyroidism, but is rarely diagnosed. So far, FHH has not been documented in Israel. This report presents preliminary evidence for the occurrence of FHH in Israel. ...

journal_title：Calcified tissue international

authors： Liel Y,Arie R,Vered I

更新日期：1997-07-01 00:00:00

abstract：:Normative bone mineral density (BMD) and bone mineral content (BMC) values for the total body (TB), proximal femur (PF), and antero-posterior lumbar spine (LS) were obtained from a large cross-sectional sample of children and adolescents who were 8-17 years of age. There were 977 scans for the TB, 892 for the PF, and ...

journal_title：Calcified tissue international

authors： Faulkner RA,Bailey DA,Drinkwater DT,McKay HA,Arnold C,Wilkinson AA

更新日期：1996-11-01 00:00:00

abstract：:Recent studies have reported that bisphosphonates reduce fracture incidence and improve bone density in children with osteogenesis imperfecta (OI). However, questions still persist concerning the effect of these drugs on bone properties such as ultrastructure and quality, particularly in the growing patient. To addres...

journal_title：Calcified tissue international

authors： Camacho NP,Raggio CL,Doty SB,Root L,Zraick V,Ilg WA,Toledano TR,Boskey AL

更新日期：2001-08-01 00:00:00

abstract：:The purpose of this study was to ascertain whether biochemical markers of bone turnover predict bone loss. The survey was carried out in Taiji, Wakayama Prefecture, Japan. From a list of inhabitants aged 40-79 years, 400 participants (50 men and 50 women in each of four age groups) were selected randomly. Bone mineral...

journal_title：Calcified tissue international

authors： Yoshimura N,Hashimoto T,Sakata K,Morioka S,Kasamatsu T,Cooper C

更新日期：1999-09-01 00:00:00

abstract：:The main congenital conditions of hypophosphatemia expressed in adulthood include several forms of hereditary hypophosphatemic rickets and a congenital disorder of vitamin D metabolism characterized by osteomalacia and hypophosphatemia in adult patients. Hypophosphatemia in adults is defined as serum phosphate concent...

journal_title：Calcified tissue international

authors： Marcucci G,Brandi ML

更新日期：2021-01-01 00:00:00

abstract：:Pleiotrophin (PTN) was found to have potent effects on regulation of osteoblast recruitment, proliferation and differentiation. The present study examined the long-term effects of targeted PTN over-expression on bone development and repair in a transgenic mouse model. Femurs and tibiae from the PTN transgenic mice and...

journal_title：Calcified tissue international

authors： Li G,Bunn JR,Mushipe MT,He Q,Chen X

更新日期：2005-04-01 00:00:00

abstract：:Risk factors for increased mortality in hip fracture patients include older age, male sex, fracture type, bone mineral density, and pre-existing co-morbidities. The role of biochemical and other anthropometric parameters on hip fracture mortality remains unclear. The aim of this study was to identify the risk factors ...

journal_title：Calcified tissue international

authors： Gulin T,Kruljac I,Kirigin L,Merc M,Pavić M,Trcin MT,Bokulić A,Megla ŽB,Kaštelan D

更新日期：2016-01-01 00:00:00

abstract：:Although hypogonadism is a risk factor for bone loss and fractures, the different etiopathophysiology and hormonal profile of classical and obesity-induced hypogonadism may lead to differences in musculoskeletal profile. This is a cross-sectional study of hypogonadal men between 40 and 74 years old. Our outcomes inclu...

journal_title：Calcified tissue international

authors： Aguirre LE,Colleluori G,Dorin R,Robbins D,Chen R,Jiang B,Qualls C,Villareal DT,Armamento-Villareal R

更新日期：2017-12-01 00:00:00

abstract：:High impact loading is known to prevent some of the age-related bone loss but its effects on the density distribution of cortical bone are relatively unknown. This study examined the effects of age and habitual sprinting on tibial and fibular mid-shaft bone traits (structural, cortical radial and polar bone mineral de...

journal_title：Calcified tissue international

authors： Rantalainen T,Duckham RL,Suominen H,Heinonen A,Alén M,Korhonen MT

更新日期：2014-08-01 00:00:00

abstract：:Micro-computed tomography (microCT) has become a standard tool for the evaluation of bone morphology in preclinical studies. Unfortunately, the user-dependent definition of contour lines that separate trabecular from cortical bone is not only extremely time-consuming but may also represent a source of data bias and in...

journal_title：Calcified tissue international

authors： Lublinsky S,Ozcivici E,Judex S

更新日期：2007-10-01 00:00:00

abstract：:Measurement of areal bone mineral density (aBMD) in intravertebral subregions may increase the diagnostic sensitivity of dual-energy X-ray absorptiometry (DXA)-derived parameters for vertebral fragility. This study investigated whether DXA-derived bone parameters in vertebral subregions were better predictors of verte...

journal_title：Calcified tissue international

authors： Briggs AM,Perilli E,Codrington J,Reynolds KJ,Parkinson IH,Wark JD

更新日期：2014-08-01 00:00:00

abstract：:Calcium and phosphate were allowed to diffuse into gelatin and Type I collagen gels which were then cut into slices and analyzed for ion concentrations. Solutions of calcium and phosphate were then prepared, with ion concentrations equivalent to the highest levels in the slices, and mixed together, whereupon a rapid a...

journal_title：Calcified tissue international

authors： Blumenthal NC,Cosma V,Gomes E

更新日期：1991-06-01 00:00:00

abstract：:The purpose of this research was to address the following question: How is the solubility of fluoride-pretreated carbonated apatite (CAP) in aqueous acidic media related to the equilibrium solution fluoride and/or the CAP adsorbed fluoride levels? A CAP sample prepared by a precipitation method at 70 degrees C contain...

journal_title：Calcified tissue international

authors： Barry AB,Zhuang H,Baig AA,Higuchi WI

更新日期：2003-03-01 00:00:00

abstract：:There are few longitudinal data on change in bone structure and muscle mass, strength and function in later life. We report these, and consider bone-muscle interrelationships in older men and women. We studied 188 men and 166 women from the Hertfordshire Cohort Study, who underwent peripheral quantitative computed tom...

journal_title：Calcified tissue international

authors： Patel A,Edwards MH,Jameson KA,Ward KA,Fuggle N,Cooper C,Dennison EM

更新日期：2018-11-01 00:00:00

abstract：:We compared the cytotoxic effects of alendronate (ALN) and incadronate (YM175) on isolated rabbit osteoclasts in vitro and on rats in vivo. In the in vitro experiment, each bisphosphonate was added to the culture of isolated osteoclasts at the final concentration of 3 x 10(-5), 3 x 10(-4), or 3 x 10(-3) M, and the amo...

journal_title：Calcified tissue international

authors： Ito M,Chokki M,Ogino Y,Satomi Y,Azuma Y,Ohta T,Kiyoki M

更新日期：1998-08-01 00:00:00

abstract：:We have previously noted that a relatively large load (150 N) is required to induce a strain on the cortex of rat vertebrae similar to that induced on weight-bearing bones by normal mechanical usage. It seems unlikely that the musculature of the tail normally imposes loads of this magnitude, and this suggests that the...

journal_title：Calcified tissue international

authors： Chow JW,Jagger CJ,Chambers TJ

更新日期：1996-08-01 00:00:00

abstract：:The present study examined calcium phosphate precipitation in aqueous suspensions of multilamellar liposomes as a possible in vitro model for matrix vesicle mineralization. Liposomes were prepared by dispersing CHCl3-evaporated thin films of 7:2:1 and 7:1:1 molar mixtures of phosphatidylcholine, dicetyl phosphate, and...

journal_title：Calcified tissue international

authors： Eanes ED,Hailer AW,Costa JL

更新日期：1984-07-01 00:00:00

abstract：:The European Forsteo Observational Study was designed to examine the effectiveness of teriparatide in postmenopausal women with osteoporosis treated for up to 18 months in normal clinical practice in eight European countries. The incidence of clinical vertebral and nonvertebral fragility fractures, back pain, and heal...

journal_title：Calcified tissue international

authors： Langdahl BL,Rajzbaum G,Jakob F,Karras D,Ljunggren O,Lems WF,Fahrleitner-Pammer A,Walsh JB,Barker C,Kutahov A,Marin F

更新日期：2009-12-01 00:00:00

abstract：:High PTH levels increase bone turnover and decrease bone mineral density (BMD). Low plasma 25-hydroxyvitamin D (25OHD) levels cause secondary hyperparathyroidism, but the relative contribution of low 25OHD and high PTH levels on risk of fracture is largely unknown. Within the cohort of women (n = 2,016) included in th...

journal_title：Calcified tissue international

authors： Rejnmark L,Vestergaard P,Brot C,Mosekilde L

更新日期：2011-03-01 00:00:00

abstract：:We had shown that aromatic amino acid (phenylalanine, tyrosine, and tryptophan) supplementation prevented bone loss in an aging C57BL/6 mice model. In vivo results from the markers of bone breakdown suggested an inhibition of osteoclastic activity or differentiation. To assess osteoclastic differentiation, we examined...

journal_title：Calcified tissue international

authors： Refaey ME,Zhong Q,Ding KH,Shi XM,Xu J,Bollag WB,Hill WD,Chutkan N,Robbins R,Nadeau H,Johnson M,Hamrick MW,Isales CM

更新日期：2014-08-01 00:00:00

abstract：:The bone mineral density (BMD) of the spine was measured in the posteroanterior (PA) and lateral projections as well as the total body BMD in 447 black and white women. The lateral projection is comprised predominantly of cancellous bone whereas the total body BMD is predominantly cortical bone, and the PA spine is in...

journal_title：Calcified tissue international

authors： Aloia JF,Vaswani A,Mikhail M,Badshah M,Flaster E

更新日期：1999-07-01 00:00:00

abstract：:The protein components of biomineralized structures (matrix proteins) are believed to modulate crystal nucleation and growth, and thereby influence the shape and strength of the final structure. The chicken eggshell contains a complex array of distinct matrix proteins. The most abundant of these was purified to homoge...

journal_title：Calcified tissue international

authors： Hincke MT,Tsang CP,Courtney M,Hill V,Narbaitz R

更新日期：1995-06-01 00:00:00

abstract：:In the rat, prolonged administration of the luteinizing, hormone-releasing hormone agonist buserelin (25 micrograms/kg body wt/day s.c.) lowers blood estradiol, raises bone resorption, and induces osteopenia. The present study was undertaken to determine whether withdrawal of buserelin normalizes blood estradiol, slow...

journal_title：Calcified tissue international

authors： Goulding A,Gold E

更新日期：1990-01-01 00:00:00

abstract：:The bone anabolic effect of parathyroid hormone (PTH) therapy is blunted when used in patients who were previously on bisphosphonate treatment. Osteocytes may play a role in the bisphosphonate silencing effect on PTH therapy since bisphosphonates have been shown to reach the lacunocanalicular system. In vivo osteocyte...

journal_title：Calcified tissue international

authors： Kuroshima S,Elliott KW,Yamashita J

更新日期：2013-06-01 00:00:00

abstract：:The small leucine-rich bone proteoglycans, biglycan and decorin, can be purified by chromatography on hydroxyapatite columns, demonstrating their potential affinities for bone apatite. To determine their effects on in vitro apatite formation and growth, a mixture of the chondroitin-sulfate (CS) bone proteoglycans, or ...

journal_title：Calcified tissue international

authors： Boskey AL,Spevak L,Doty SB,Rosenberg L

更新日期：1997-10-01 00:00:00