Subregional DXA-derived vertebral bone mineral measures are stronger predictors of failure load in specimens with lower areal bone mineral density, compared to those with higher areal bone mineral density.

abstract：:Identifying persons with a high risk of osteoporotic fractures remains a challenge. DXA uptake in women with elevated risk of osteoporosis seems to be depending on distance to scanning facilities. This study aimed to investigate the ability of a small portable scanner in identifying women with reduced bone mineral den...

journal_title：Calcified tissue international

authors： Holmberg T,Bech M,Gram J,Hermann AP,Rubin KH,Brixen K

更新日期：2016-03-01 00:00:00

abstract：:Sulfotransferase 1E1 (SULT1E1) catalyze estrogen into sulfate conjugation and is involved in the metabolism of phytoestrogen. A community-based cross-sectional study was conducted on 397 Korean women, to evaluate the association between genetic polymorphisms of SULT1E1 and bone mineral density (BMD) and the combined e...

journal_title：Calcified tissue international

authors： Lee SA,Choi JY,Shin CS,Hong YC,Chung H,Kang D

更新日期：2006-09-01 00:00:00

abstract：:Bone and mineral metabolism has been reported to affect the development of the ossification of the posterior longitudinal ligament (OPLL). The aim of this study was to compare bone mineral densities (BMD) and rate of osteoporosis between cervical OPLL and a matched control group. We also investigated the correlation o...

journal_title：Calcified tissue international

authors： Sohn S,Chung CK

更新日期：2013-01-01 00:00:00

abstract：:The dentin-enamel junction (DEJ) plays an important role in preventing crack propagation from enamel into dentin. This function stems from its complex structure and materials properties that are different from either dentin or enamel. The molecular structural differences in both mineral and organic matrix across the D...

journal_title：Calcified tissue international

authors： Xu C,Yao X,Walker MP,Wang Y

更新日期：2009-03-01 00:00:00

abstract：:The usefulness of various bone mineral measurement techniques is a subject of current controversy. In order to explore whether disparate conclusions may have arisen from differences in analytic methodology, data from published reports of bone mass and nonviolent fractures have been reanalyzed in terms of fracture risk...

journal_title：Calcified tissue international

authors： Ross PD,Davis JW,Vogel JM,Wasnich RD

更新日期：1990-03-01 00:00:00

abstract：:Histomorphometric evaluation of bone formation in an intravital tetracycline-labeled skeleton of a suddenly deceased osteoporotic woman is presented. The 24 skeletal sites investigated displayed substantial regional variations which, for two out of four cortical bone dynamics and all trabecular bone dynamics, were sig...

journal_title：Calcified tissue international

authors： Pødenphant J,Engel U

更新日期：1987-04-01 00:00:00

abstract：:Plasma membrane vesicles were prepared from chicken osteoclasts, and active calcium transport was demonstrated in a spectrofluorimetric assay using the fluorescent calcium concentration indicator, fura-2. Transport activity was inhibited by quercetin (10 microM), sodium vanadate (10 microM), and the anticalmodulin age...

journal_title：Calcified tissue international

authors： Bekker PJ,Gay CV

更新日期：1992-10-01 00:00:00

abstract：:Bone mineralization density distribution (BMDD) is an important determinant of bone mechanical properties. The most available skeletal site for access to the BMDD is the iliac crest. Compared to cancellous bone much less information on BMDD is available for cortical bone. Hence, we analyzed complete transiliac crest b...

journal_title：Calcified tissue international

authors： Misof BM,Dempster DW,Zhou H,Roschger P,Fratzl-Zelman N,Fratzl P,Silverberg SJ,Shane E,Cohen A,Stein E,Nickolas TL,Recker RR,Lappe J,Bilezikian JP,Klaushofer K

更新日期：2014-10-01 00:00:00

abstract：:The crystallinity of bone mineral at different stages of maturation has been measured by quantitative X-ray diffraction methods. Crystallinity measurements were made on tibial mid-diaphyses from 17-day embryonic chicks, newly-formed periosteal bone from embryonic chicks, and density-fractionated bone from post-hatch c...

journal_title：Calcified tissue international

authors： Bonar LC,Roufosse AH,Sabine WK,Grynpas MD,Glimcher MJ

更新日期：1983-01-01 00:00:00

abstract：:Data have accumulated to show that various types of collagen crosslinking are implicated in the health of individuals, as well as in a number of disease states, such as osteoporosis, diabetes mellitus, chronic kidney disease, inflammatory bowel disease, or in conditions of mild hyperhomocysteinemia, or when glucocorti...

journal_title：Calcified tissue international

authors： Saito M,Marumo K

更新日期：2015-09-01 00:00:00

abstract：:Adiponectin, a protein classically known to be secreted by adipocytes, is also secreted by bone-forming cells. Results of previous studies have been contradictory as to whether serum adiponectin and bone mineral density (BMD) are associated. The aim of this study was to investigate a possible association between serum...

journal_title：Calcified tissue international

authors： Frost M,Abrahamsen B,Nielsen TL,Frystyk J,Flyvbjerg A,Hagen C,Andersen M,Brixen K

更新日期：2010-07-01 00:00:00

abstract：:Bruck syndrome is a rare autosomal recessive form of osteogenesis imperfecta (OI), which is mainly characterized by joint contractures and recurrent fragility fractures. Mutations in FKBP10 and PLOD2 were identified as the underlying genetic defects of Bruck syndrome. Here we investigated the phenotypes and the pathog...

journal_title：Calcified tissue international

authors： Lv F,Xu X,Song Y,Li L,Asan,Wang J,Yang H,Wang O,Jiang Y,Xia W,Xing X,Li M

更新日期：2018-03-01 00:00:00

abstract：:Acute spinal cord injury is associated with rapid bone loss and an increased risk of fracture. In this double-blind, randomized, placebo-controlled trial, 17 patients were followed for 1 year after administration of either 4 or 5 mg of zoledronic acid or placebo. Bone mineral density (BMD) and structural analyses of t...

journal_title：Calcified tissue international

authors： Shapiro J,Smith B,Beck T,Ballard P,Dapthary M,BrintzenhofeSzoc K,Caminis J

更新日期：2007-05-01 00:00:00

abstract：:The aim of this work was a preliminary assessment of the feasibility of using in vivo measurements of mechanical properties of bones to detect mineral loss and further to relate them to the tendency of the bone to fracture in the case of loss of minerals, such as in osteoporosis. Previous studies of bone strength in v...

journal_title：Calcified tissue international

authors： Dimarogonas AD,Abbasi-Jahromi SH,Avioli LV

更新日期：1993-03-01 00:00:00

abstract：:We have recently reported that risedronate preserves normal bone formation and decreases bone remodeling in women with postmenopausal osteoporosis after 3 years of treatment. We report now the results of a 2-year extension study. The primary objective of this study was to determine the effect of 5 years of risedronate...

journal_title：Calcified tissue international

authors： Ste-Marie LG,Sod E,Johnson T,Chines A

更新日期：2004-12-01 00:00:00

abstract：:It has been well established that bone morphogenetic protein-2 (BMP-2) can induce bone formation bothin vivo andin vitro, although high concentrations (up to milligrams) of BMP-2 have been required to achieve this effectin vivo. Further, clinical applications are usually limited to a single dose at the time of implant...

journal_title：Calcified tissue international

authors： Cheng SL,Lou J,Wright NM,Lai CF,Avioli LV,Riew KD

更新日期：2001-02-01 00:00:00

abstract：:Crouzon syndrome is a debilitating congenital disorder involving abnormal craniofacial skeletal development caused by mutations in fibroblast growth factor receptor-2 (FGFR2). Phenotypic expression in humans exhibits an autosomal dominant pattern that commonly involves premature fusion of the coronal suture (craniosyn...

journal_title：Calcified tissue international

authors： Liu J,Nam HK,Wang E,Hatch NE

更新日期：2013-05-01 00:00:00

abstract：:The goal of this study was to find out if bone can recover after long-term administration of bisphosphonate. Disodium pamidronate (APD) was given orally by gavage to mature beagle dogs at doses of 0, 2.5, 12.5, and 25 mg/kg/day for 1 year (0.1% concentration) and the animals were allowed to recover for another year. A...

journal_title：Calcified tissue international

authors： Grynpas MD,Kasra M,Dumitriu M,Nespeca R,Very JM,Mertz BP

更新日期：1994-10-01 00:00:00

abstract：:Mandibular first molars from 17-day-old mouse embryos were cultivated in vitro for 10 days using a new organ culture method. This method consisted of using a small glass dish and an agar chamber to slowly float the molars to the gas-medium interface where they were maintained by the surface tension of the medium. The ...

journal_title：Calcified tissue international

authors： Sakakura Y

更新日期：1986-10-01 00:00:00

abstract：:The phorbol ester 12-O-tetradecanoyl-13-acetate (TPA) blocked the growth of, and induced the appearance of processes in the human osteosarcoma cell line U-2 OS. The phorbol ester decreased the intracellular level of alkaline phosphatase (APase) activity (as measured per mg cell protein) and caused a marked increase in...

journal_title：Calcified tissue international

authors： Ringbom-Anderson T,Akerman KE

更新日期：1992-06-01 00:00:00

abstract：:To assess the usefulness of the measurement of the os calcis by ultrasound, a method that probably reflects bone quality as well as density, we have studied 54 women with hip fracture of the proximal femur and a control group. Ultrasound evaluation of the os calcis [broadband ultrasound attenuation (BUA), speed of the...

journal_title：Calcified tissue international

authors： Mautalen C,Vega E,González D,Carrilero P,Otaño A,Silberman F

更新日期：1995-09-01 00:00:00

abstract：:Teriparatide (TPTD) is the most widely used anabolic agent in the treatment of patients with osteoporosis although its use is restricted in many countries. A recent randomised trial confirmed that TPTD was superior to risedronate at preventing vertebral fractures over a 2-year period. There is limited information on t...

journal_title：Calcified tissue international

authors： Oswald AJ,Berg K,Ralston SH,Riches PL

更新日期：2019-08-01 00:00:00

abstract：:This study examined effects of bone bonding and nonbonding implants on parameters associated with matrix vesicle-mediated primary bone formation, matrix vesicle alkaline phosphatase and phospholipase A2 specific activities, and phosphatidylserine content. Tibia marrow ablation followed by implantation of KG-Cera, Mina...

journal_title：Calcified tissue international

authors： Schwartz Z,Swain LD,Marshall T,Sela J,Gross U,Amir D,Muller-Mai C,Boyan BD

更新日期：1992-12-01 00:00:00

abstract：:The evidence now strongly supports a central role for oestrogen in the maintenance of the normal female skeleton. Loss of endogenous oestrogen leads to a period of accelerated bone loss which can be prevented with appropriate oestrogen replacement. The route of administration is not important provided adequate dosages...

journal_title：Calcified tissue international

authors： Hillard TC,Stevenson JC

更新日期：1991-01-01 00:00:00

abstract：:Osteoblasts in vitro differentiate from a proliferating to a mineralizing phenotype upon transfer to a medium rich in beta-glycerophosphate and ascorbic acid. The nutritional requirements of the cells at different stages of this differentiation process are not known. In other cell types, nutritional supplementation du...

journal_title：Calcified tissue international

authors： Brown PM,Hutchison JD,Crockett JC

更新日期：2011-12-01 00:00:00

abstract：:In the past years, several epidemiological and clinical observations have underlined the importance of genetics in the pathogenesis of both female and male osteoporosis. It has been estimated that from 50 to 80% of the inter-individual variability in bone mass is genetically determined. In rare instances, osteoporosis...

journal_title：Calcified tissue international

authors： Gennari L,Brandi ML

更新日期：2001-10-01 00:00:00

abstract：:The low interference with growth expected in child for a cortisol analogue, deflazacort (DFZ), prompted us to verify if DFZ could affect growth less than prednisone (PDN). An interim analysis relative to 27 girls and 38 boys (out of 100 expected) aged 3-12 yrs, after a median period of 14 mo.s is reported. Children wi...

journal_title：Calcified tissue international

authors： Aicardi G,Milani S,Imbimbo B,Vignolo M,Di Battista E,Gusmano R,Terragna A,Cordone G,Cottafava F,Coppo R

更新日期：1991-04-01 00:00:00

abstract：:Atomic force microscopy (AFM) was used to obtain three-dimensional images of isolated mineralites extracted from young postnatal bovine bone. The mean mineralite size is 9 nm x 6 nm x 2.0 nm, significantly shorter and thicker than the mineralites of mature bovine bone measured by the same technique. Mineralites of the...

journal_title：Calcified tissue international

authors： Tong W,Glimcher MJ,Katz JL,Kuhn L,Eppell SJ

更新日期：2003-05-01 00:00:00

abstract：:Extracellular ATP, and to a lesser extent adenosine, an ATP metabolite, stimulated cell proliferation in osteoblast-like cells (MC3T3-E1). ATP increased cytosolic Ca2+ due to Ca2+ mobilization from intracellular storage in the same concentration range of the nucleotide as that effective for DNA synthesis, suggesting t...

journal_title：Calcified tissue international

authors： Shimegi S

更新日期：1996-02-01 00:00:00

abstract：:Patients with systemic lupus erythematosus (SLE), a chronic inflammatory disease characterized by loss of T- and B-cell tolerance to autoantigens, are at increased risk for osteoporosis and fractures. Mice deficient in Fc gamma receptor IIb (FcγRIIB) exhibit spontaneous SLE and its restoration rescues the disease. To ...

journal_title：Calcified tissue international

authors： Saiworn W,Thim-Uam A,Visitchanakun P,Atjanasuppat K,Chantaraaumporn J,Mokdara J,Chungchatupornchai S,Pisitkun P,Leelahavanichkul A,Poolthong S,Baron R,Lotinun S

更新日期：2018-12-01 00:00:00