How to prevent perioperative myocardial injury: the conundrum continues.

abstract：:Nitrates are widely used for the management of congestive heart failure (CHF), as well as angina pectoris. In both situations, nitrates significantly increase exercise capacity. The mechanism of this beneficial effect is unclear, especially in CHF. Isosorbide dinitrate reduces pulmonary capillary wedge pressure (PCWP)...

journal_title：American heart journal

authors： Franciosa JA

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:31-Phosphorus-magnetic resonance spectroscopy may provide pathophysiological insights into the high-energy phosphate metabolism of the myocardium as measured by phosphocreatine to adenosine triphosphate (PCr/ATP) ratio. Aim of the present study was to determine in vivo the relation between cardiac PCr/ATP ra...

journal_title：American heart journal

authors： Fragasso G,De Cobelli F,Spoladore R,Esposito A,Salerno A,Calori G,Montanaro C,Maranta F,Lattuada G,Margonato A,Del Maschio A,Perseghin G

更新日期：2011-07-01 00:00:00

abstract：:The present generation of implantable cardioverter defibrillators (ICDs) provides a very effective device for monitoring and treating life-threatening ventricular tachyarrhythmia. Patients at risk of sudden cardiac death who are directed to this form of treatment usually have severe coronary artery disease, previous m...

journal_title：American heart journal

authors： Zehender M,Faber T,Grom A,Schwab T,Geibel A,Meinertz T,Just H

更新日期：1994-04-01 00:00:00

abstract：:Recently, the theory that hyperinflammation is the body's primary response to potent stimulus has been challenged. Indeed, a deregulation of the immune system could be the cause of multiple organ failure. So far, clinicians have focused on the last steps of the inflammatory cascade. However, little attention has been ...

journal_title：American heart journal

authors： Bodi V,Sanchis J,Nunez J,Mainar L,Minana G,Benet I,Solano C,Chorro FJ,Llacer A

更新日期：2008-12-01 00:00:00

abstract：AIMS:Furosemide is commonly prescribed for symptom relief in heart failure (HF) patients. Although few data support the continuous use of loop diuretics in apparently euvolemic HF patients with mild symptoms, there is concern about safety of diuretic withdrawal in these patients. The ReBIC-1 trial was designed to evalu...

journal_title：American heart journal

authors： da Rosa PR,Rohde LE,Doebber M,Ribeiro ALP,Prado DP,Bertoldi EG,Figueiredo Neto JA,Kohler I,Beck-da-Silva L,Danzmann LC,Moura LZ,Rover M,Simões MV,Sant'Anna RT,Biolo A

更新日期：2017-12-01 00:00:00

abstract：:The response of S1 amplitude to exercise stress was investigated in patients with coronary heart disease. Phonocardiograms were recorded at rest and during a multistage bicycle ergometer exercise test in a group of 22 patients with angina pectoris and documented coronary disease, and in a normal control group comprise...

journal_title：American heart journal

authors： Bergman ST Jr,Blomqvist CG

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:The purpose of the current study was to determine whether survival after revascularization (coronary artery bypass grafting or percutaneous transluminal coronary angioplasty) is influenced by the extent of electrocardiographic (ECG) evidence of previous myocardial infarction (MI) in patients with ischemic ca...

journal_title：American heart journal

authors： Shah BR,Velazquez E,Shaw LK,Bart B,O'Connor C,Wagner GS

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Protease-activated receptor 1 antagonism with vorapaxar represents a novel strategy for platelet inhibition. In TRACER, vorapaxar was compared with placebo plus standard of care among 12,944 patients with non-ST-segment elevation acute coronary syndromes. We anticipated that most patients would have received...

journal_title：American heart journal

authors： Tricoci P,Lokhnygina Y,Huang Z,Van de Werf F,Cornel JH,Chen E,Wallentin L,Held C,Aylward PE,Moliterno DJ,Jennings LK,White HD,Armstrong PW,Harrington RA,Strony J,Mahaffey KW

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Recent work has demonstrated a link between retinopathy, a marker of microvascular disease, and the development of heart failure, a finding particularly relevant in individuals with diabetes. Our objective was to assess the relationship between retinopathy and cardiac structure and function in a cohort of in...

journal_title：American heart journal

authors： Aguilar D,Hallman DM,Piller LB,Klein BE,Klein R,Devereux RB,Arnett DK,Gonzalez VH,Hanis CL

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:In the TRACER trial, vorapaxar, a protease-activated receptor-1 antagonist, plus standard care in non-ST-segment elevation acute coronary syndrome (NSTE ACS) patients did not significantly reduce the primary composite end point but reduced a key secondary end point and significantly increased bleeding. Histo...

journal_title：American heart journal

authors： Jones WS,Tricoci P,Huang Z,Moliterno DJ,Harrington RA,Sinnaeve PR,Strony J,Van de Werf F,White HD,Held C,Armstrong PW,Aylward PE,Chen E,Patel MR,Mahaffey KW

更新日期：2014-10-01 00:00:00

abstract：:We studied the diagnostic value of exercise electrocardiographic (ECG) testing in 191 patients who were completely asymptomatic 6 months after a successful percutaneous transluminal coronary angioplasty procedure. With > 70%- and > 50%-diameter stenosis at follow-up as restenosis criteria, the sensitivities of exercis...

journal_title：American heart journal

authors： Desmet W,De Scheerder I,Piessens J

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Despite the known benefits of cardiac rehabilitation in patients with coronary artery disease, referral rates to rehabilitation programs remain low. We determined the incidence and determinants of cardiac rehabilitation referral rates for patients undergoing percutaneous coronary intervention (PCI). METHODS...

journal_title：American heart journal

authors： Aragam KG,Moscucci M,Smith DE,Riba AL,Zainea M,Chambers JL,Share D,Gurm HS

更新日期：2011-03-01 00:00:00

abstract：:The incidence and prognosis of acute coronary reocclusion occurring after patients had left the catheterization laboratory following a successful percutaneous transluminal coronary angioplasty (PTCA) procedure and the temporal relation of this event to the discontinuation of systemic heparin administration were analyz...

journal_title：American heart journal

authors： Gabliani G,Deligonul U,Kern MJ,Vandormael M

更新日期：1988-09-01 00:00:00

abstract：AIMS:There is a growing concern about the occurrence of coronary artery aneurysms (CAAs) after drug-eluting stent (DES) implantation and their long-term course. We assessed the occurrence and the factors affecting the long-term outcome of DES-associated CAA. METHODS AND RESULTS:We analyzed 3,612 consecutive patients (...

journal_title：American heart journal

authors： Ahn CM,Hong BK,Kim JY,Min PK,Yoon YW,Lee BK,Kwon HM,Kim JS,Ko YG,Choi D,Hong MK,Jang Y,Shim WH,Cho SY,Kim BK,Oh S,Jeon DW,Yang JY,Jung JH

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:This study examines how the dissemination of stenting and procedural shifts to high-volume facilities have affected short-term outcomes after percutaneous coronary intervention (PCI). METHODS:Discharge information from the 1994 and 1997 US Nationwide Inpatient Sample was used. Data from 1994 involved 84,036...

journal_title：American heart journal

authors： Watanabe CT,Maynard C,Ritchie JL

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVES:We aim to review the studies comparing coronary calcification across different ethnic groups. BACKGROUND:There is still uncertainty regarding ethnic differences in the prevalence, progression, and risk of coronary artery disease. Clues to possible racial differences in rates of coronary heart disease (CHD) ...

journal_title：American heart journal

authors： Orakzai SH,Orakzai RH,Nasir K,Santos RD,Edmundowicz D,Budoff MJ,Blumenthal RS

更新日期：2006-11-01 00:00:00

abstract：:We developed a new angiographic score of the extent of coronary disease (extent score), which we compared with conventional stenosis and vessel scores that emphasize the severity of stenosis. Scores were determined in 132 patients (29 women, 103 men with a mean age of 55 +/- 10 years) who underwent elective coronary a...

journal_title：American heart journal

authors： Sullivan DR,Marwick TH,Freedman SB

更新日期：1990-06-01 00:00:00

abstract：:A double-blind multicenter study compared oral acebutolol (n = 182) with hydrochlorothiazide (n = 178) in the treatment of mild to moderate essential hypertension (diastolic blood pressure 95 to 114 mm Hg). Both agents produced significant and comparable reductions in systolic, diastolic, and mean arterial blood press...

journal_title：American heart journal

authors： Wahl J,Singh BN,Thoden WR

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Early reperfusion therapy improves the clinical outcomes of patients with acute myocardial infarction (AMI), but benefits are limited by reperfusion injury in some patients. We examined the effect of nicorandil, a hybrid of K(ATP) channel opener and nicotinamide nitrate, on reactive oxygen species (ROS) form...

journal_title：American heart journal

authors： Ono H,Osanai T,Ishizaka H,Hanada H,Kamada T,Onodera H,Fujita N,Sasaki S,Matsunaga T,Okumura K

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Diabetic nephropathy is associated with increased cardiovascular events. Coronary atherosclerosis is responsible for many of these events, but other mechanisms such as impaired flow reserve may be involved. The purpose of this study was to define the prevalence and mechanism of abnormal coronary velocity res...

journal_title：American heart journal

authors： Ragosta M,Samady H,Isaacs RB,Gimple LW,Sarembock IJ,Powers ER

更新日期：2004-06-01 00:00:00

abstract：:Left circumflex coronary blood flow was increased significantly (20 per cent) during stimulation of somatic afferent fibers. The change in CBF was associated with significant increases in heart rate and arterial pressure and significant decrease in coronary vascular resistance. Controlling heart rate or preventing car...

journal_title：American heart journal

authors： Kline RL

更新日期：1979-07-01 00:00:00

abstract：:The efficacy and safety of sotalol therapy for ventricular arrhythmias was evaluated in 133 patients with drug-refractory ventricular arrhythmias. All patients had baseline electrophysiologic studies before and after oral sotalol therapy. Sixty-six patients were discharged home, treated with sotalol (52 patients witho...

journal_title：American heart journal

authors： Lee RJ,Wong M,Siu A,Namekawa-Wong M,Epstein LM,Fitzpatrick AP,Grogin HR,Scheinman MM,Lesh MD

更新日期：1996-11-01 00:00:00

abstract：:Although many patients with coronary artery disease (CAD) have a positive exercise test without pain, the frequency and significance of this "silent" ischemia is unclear. Therefore, we studied 122 consecutive clinically stable patients with angiographically defined CAD (greater than 75 per cent luminal stenosis) and a...

journal_title：American heart journal

authors： Lindsey HE Jr,Cohn PF

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Aortopulmonary collaterals (APCs) are frequently observed before and after the Fontan procedure. However, the mechanism of the development of APCs is unknown. We hypothesized that one or several antiangiogenic and/or angiogenic growth factors might play a role in the development of APCs. METHODS:Eighty-five...

journal_title：American heart journal

authors： Mori Y,Shoji M,Nakanishi T,Fujii T,Nakazawa M

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Anemia in heart failure is both common and associated with worse symptoms and increased mortality. Several small randomized controlled trials (RCTs) have assessed erythropoiesis-stimulating agents (ESAs), but definitive evaluation and clinical guidance are required. We sought to systematically review the eff...

journal_title：American heart journal

authors： Kotecha D,Ngo K,Walters JA,Manzano L,Palazzuoli A,Flather MD

更新日期：2011-05-01 00:00:00

abstract：:To clarify the difference between alcoholic cardiomyopathy and dilated cardiomyopathy and to investigate the characteristics of alcoholic cardiomyopathy, right ventricular endomyocardial biopsy was performed, and the two diseases were compared clinically and histologically. Changes in the cardiothoracic ratio, cardiac...

journal_title：American heart journal

authors： Teragaki M,Takeuchi K,Takeda T

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Bleeding and blood transfusion are associated with increased morbidity and mortality among patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS); however, the economic consequences of these complications are not well defined. We sought to determine the relationship between bleeding, bloo...

journal_title：American heart journal

authors： Rao SV,Kaul PR,Liao L,Armstrong PW,Ohman EM,Granger CB,Califf RM,Harrington RA,Eisenstein EL,Mark DB

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Invasive coronary angiography (ICA) alone fails to accurately select patients with intermediate stenoses who should be treated by percutaneous coronary intervention (PCI). Previous studies have demonstrated the usefulness of fractional flow reserve (FFR) for identifying patients in whom deferring an intended...

journal_title：American heart journal

authors： Rieber J,Jung P,Koenig A,Schiele T,Shapiro M,Hoffmann U,Klauss V

更新日期：2007-03-01 00:00:00

abstract：:To evaluate the mechanisms involved in nitrate tolerance, we randomized 23 patients with congestive heart failure resulting from coronary artery disease to an isosorbide dinitrate or a molsidomine infusion. The drugs were titrated to decrease pulmonary capillary wedge pressure by > or = 30% or > or = 10 mm Hg. Then is...

journal_title：American heart journal

authors： Unger P,Vachiery JL,de Cannière D,Staroukine M,Berkenboom G

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Chest pain in the absence of obstructive coronary artery disease (CAD) is common in women; it is frequently associated with debilitating symptoms and repeated evaluations and may be caused by coronary microvascular dysfunction. However, the prevalence and determinants of microvascular dysfunction in these wo...

journal_title：American heart journal

authors： Reis SE,Holubkov R,Conrad Smith AJ,Kelsey SF,Sharaf BL,Reichek N,Rogers WJ,Merz CN,Sopko G,Pepine CJ,WISE Investigators.

更新日期：2001-05-01 00:00:00