Clinical and histologic features of alcohol drinkers with congestive heart failure.

Abstract:

:To clarify the difference between alcoholic cardiomyopathy and dilated cardiomyopathy and to investigate the characteristics of alcoholic cardiomyopathy, right ventricular endomyocardial biopsy was performed, and the two diseases were compared clinically and histologically. Changes in the cardiothoracic ratio, cardiac index, and systolic blood pressure/end-systolic volume index were greater after treatment in patients with alcoholic cardiomyopathy than in patients with dilated cardiomyopathy. Histologically, myocytic hypertrophy, fibrosis, and nuclear change were less significant in the former than in the latter. Among patients with alcoholic cardiomyopathy, the cardiac index in those with less fibrosis was greater than in those with more fibrosis. Thus patients with alcoholic cardiomyopathy had more preserved and reversible cardiac function and fewer histologic changes than the patients with dilated cardiomyopathy. Reversibility of cardiac function in patients with alcoholic cardiomyopathy correlated inversely with the severity of histologic changes.

journal_name

Am Heart J

journal_title

American heart journal

authors

Teragaki M,Takeuchi K,Takeda T

doi

10.1016/0002-8703(93)90175-9

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

808-17

issue

3

eissn

0002-8703

issn

1097-6744

pii

0002-8703(93)90175-9

journal_volume

125

pub_type

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