Origin of the basal systolic murmurs in mitral stenosis. A study with intracardiac phonocardiography.

abstract：BACKGROUND:Diastolic heart failure (DHF) is characterized by dyspnea due to increased left ventricular (LV) filling pressures during stress. We sought the relationship of exercise-induced increases in B-type natriuretic peptide (BNP) to LV filling pressures and parameters of cardiovascular performance in suspected DHF....

journal_title：American heart journal

authors： Mottram PM,Haluska BA,Marwick TH

更新日期：2004-08-01 00:00:00

abstract：:The electrocardiographic QT interval, with a wide variety of practical and theoretic applications in medicine, pharmacology, and cardiology, is critically dependent on heart rate as expressed by cycle length (RR). To account for this and permit intraindividual and interindividual comparisons of changing QT intervals, ...

journal_title：American heart journal

authors： Spodick DH,Rifkin RD,Rajasingh MC

更新日期：1990-07-01 00:00:00

abstract：:In older patients (70 ± 7 years) with chronic well-compensated heart failure with preserved ejection and controlled blood pressure, 6 months treatment with aliskiren (direct renin inhibitor) showed non-significant trends for modest improvements in peak exercise oxygen consumption (14.9 ± 0.2 mL kg-1 min-1 versus 14.4 ...

journal_title：American heart journal

authors： Upadhya B,Brubaker PH,Morgan TM,Eggebeen JD,Jao GT,Stewart KP,Kitzman DW

更新日期：2018-07-01 00:00:00

abstract：:Myocardial ischemia, electrolyte changes, and fluctuations in autonomic tone may play an important role in the presentation of malignant ventricular arrhythmias. beta-Adrenoceptor blocking agents have been shown to decrease the incidence of ventricular fibrillation and sudden cardiac death in patients with coronary ar...

journal_title：American heart journal

authors： Peuhkurinen KJ,Huikuri HV,Linnaluoto M,Takkunen JT

更新日期：1994-07-01 00:00:00

abstract：:In 14 patients with severe congestive heart failure, the effects of captopril on the forearm circulation were evaluated with strain gauge plethysmography. Changes in plasma renin activity, angiotensin II, norepinephrine, epinephrine, bradykinin, prostaglandin E2, and 6-keto-prostaglandin F1 alpha concentrations were a...

journal_title：American heart journal

authors： Nishimura H,Kubo S,Ueyama M,Kubota J,Kawamura K

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) ablation is superior to pharmacologic therapy in achieving maintenance of normal sinus rhythm in selected patient populations. However, the procedure is resource intensive, and repeat ablations are sometimes required. We examined the predictors and trends of repeat ablation using a l...

journal_title：American heart journal

authors： Al-Hijji MA,Deshmukh AJ,Yao X,Mwangi R,Sangaralingham LR,Friedman PA,Asirvatham SJ,Packer DL,Shah ND,Noseworthy PA

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Our goal was to evaluate cross-sectionally the association between ideal risk factor (IRF) profile and the presence and severity of subclinical atherosclerosis measured as coronary artery calcium (CAC) in the Brazilian Longitudinal Study of Adult Health. METHODS:We included 4,077 participants with no prior ...

journal_title：American heart journal

authors： Bensenor IM,Goulart AC,Santos IS,Bittencourt MS,Pereira AC,Santos RD,Nasir K,Blankstein R,Lotufo PA

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:The purpose of our study was to evaluate the implementation of guidelines for the treatment of cardiogenic shock (CS) complicating the acute coronary syndromes (ACS). METHODS AND RESULTS:Of the 10 136 patients in the Euro-Heart-Survey-ACS with complete data, CS occurred in 549 (5.4%), of whom 28.6% had CS u...

journal_title：American heart journal

authors： Iakobishvili Z,Behar S,Boyko V,Battler A,Hasdai D

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:31-Phosphorus-magnetic resonance spectroscopy may provide pathophysiological insights into the high-energy phosphate metabolism of the myocardium as measured by phosphocreatine to adenosine triphosphate (PCr/ATP) ratio. Aim of the present study was to determine in vivo the relation between cardiac PCr/ATP ra...

journal_title：American heart journal

authors： Fragasso G,De Cobelli F,Spoladore R,Esposito A,Salerno A,Calori G,Montanaro C,Maranta F,Lattuada G,Margonato A,Del Maschio A,Perseghin G

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Increasing numbers of balloon aortic valvuloplasty (BAV) are performed in the management of symptomatic aortic stenosis as bridge and therapeutic challenge in the work-up for transcatheter aortic valve replacement. However, the significance of gender in outcomes following BAV remains controversial. METHODS:...

journal_title：American heart journal

authors： Christodoulidis G,Yu J,Kini A,Dangas GD,Baber U,Melissa A,Sartori S,Theodoropoulos K,Bhat A,Kovacic J,Moreno P,Krishnan P,Mehran R,Sharma S

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:African-American ancestry, hypokalemia, and QT interval prolongation on the electrocardiogram are all risk factors for sudden cardiac death (SCD), but their interactions remain to be characterized. SCN5A-1103Y is a common missense variant, of African ancestry, of the cardiac sodium channel gene. SCN5A-1103Y ...

journal_title：American heart journal

authors： Akylbekova EL,Payne JP,Newton-Cheh C,May WL,Fox ER,Wilson JG,Sarpong DF,Taylor HA,Maher JF

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:To date, considerable controversy exists on the prognostic significance of morphometric endomyocardial biopsy findings in patients with idiopathic dilated cardiomyopathy (IDC). METHODS:Quantitative analyses of interstitial structured tissue, myofibril volume fraction, and myocytic fiber diameters of left ve...

journal_title：American heart journal

authors： Grimm W,Rudolph S,Christ M,Pankuweit S,Maisch B

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:The diagnostic value of 12-lead electrocardiography during dobutamine stress echocardiography (DSE) is not well documented. METHODS AND RESULTS:We reviewed the records of 116 patients referred for DSE and coronary angiography, 52 of whom were excluded because of abnormal ST segment or inadequate DSE. Of the...

journal_title：American heart journal

authors： Shaheen J,Luria D,Klutstein MW,Rosenmann D,Tzivoni D

更新日期：1998-12-01 00:00:00

abstract：:To determine whether a dose of 5 mg of nifedipine would be useful in the treatment of hypertensive emergencies, we compared the acute hypotensive effects of two different doses of nifedipine, 5 mg and 10 mg, in patients with severe hypertension. In this prospective, randomized, double-blind study, 30 consecutive black...

journal_title：American heart journal

authors： Maharaj B,van der Byl K

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:the objective of the study was to determine whether the effects of infarct-related artery (IRA) infusion of autologous bone marrow-derived CD34(+) cells after ST elevation myocardial infarction (STEMI) are dependent on the dose (quantity and mobility) of the cells infused. Beneficial effects of IRA infusion ...

journal_title：American heart journal

authors： Quyyumi AA,Waller EK,Murrow J,Esteves F,Galt J,Oshinski J,Lerakis S,Sher S,Vaughan D,Perin E,Willerson J,Kereiakes D,Gersh BJ,Gregory D,Werner A,Moss T,Chan WS,Preti R,Pecora AL

更新日期：2011-01-01 00:00:00

abstract：:To investigate the influence of intrinsic limb vasodilator capacity on exercise performance, limb reactive hyperemic flows and their relations to exercise capacity during upright bicycle exercise were examined in 52 patients with recent myocardial infarction. Reactive hyperemic flow was measured in the forearm and the...

journal_title：American heart journal

authors： Hattori T,Sumimoto T,Yuasa F,Kaida M,Jikuhara T,Hikosaka M,Sugiura T,Iwasaka T

更新日期：1996-09-01 00:00:00

abstract：:An extremely athletic 56-year-old male physician was found to have profound sinus bradycardia. His only symptom was markedly increased alertness while actively exercising. During pacemaker insertion he had an episode of prolonged sinus arrest terminated by a precordial thump. This case suggests that exercise can alter...

journal_title：American heart journal

authors： Marmor BM,Black MM

更新日期：1980-07-01 00:00:00

abstract：:Fourteen fetuses with atrioventricular canal malformations were examined by two-dimensional echocardiography, pulsed-wave Doppler echocardiography, and color Doppler flow mapping. Eleven fetuses had complete and three fetuses had partial atrioventricular canal malformations. Nonimmune hydrops fetalis was associated wi...

journal_title：American heart journal

authors： Gembruch U,Knöpfle G,Chatterjee M,Bald R,Redel DA,Födisch HJ,Hansmann M

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:This study was designed to determine if vertically transmitted HIV infection and maternal infection with HIV are associated with altered cardiovascular structure and function in utero. METHODS:Fetal echocardiography was performed in 173 fetuses of 169 HIV-infected mothers (mean gestational age, 33.0 weeks; ...

journal_title：American heart journal

authors： Hornberger LK,Lipshultz SE,Easley KA,Colan SD,Schwartz M,Kaplan S,Starc TJ,Ayres NA,Lai WW,Moodie DS,Kasten-Sportes C,Sanders SP

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:The optimal duration of dual antiplatelet therapy (DAPT) in acute coronary syndrome (ACS) patients treated with drug eluting stents (DES) is still under debate. Recent meta-analyses on ≤6months versus 12months DAPT suggest that bleeding rates can be reduced, without a higher rate of thrombotic complications....

journal_title：American heart journal

authors： Camaro C,Damen SA,Brouwer MA,Kedhi E,Lee SW,Verdoia M,Barbieri L,Rognoni A,van T Hof AW,Ligtenberg E,de Boer MJ,Suryapranata H,De Luca G

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Multidisciplinary disease management programs (MDMP) have demonstrated reduced hospitalizations in motivated pretransplant heart failure populations, but little is known about their effectiveness in largely indigent patients who are not transplant candidates. METHODS AND RESULTS:We studied 35 patients with ...

journal_title：American heart journal

authors： O'Connell AM,Crawford MH,Abrams J

更新日期：2001-02-01 00:00:00

abstract：:Intracoronary streptokinase (SK) was administered to 11 patients with evolving acute transmural myocardial infarction 5.5 +/- 0.4 hours from the onset of symptoms. Ten patients (91%) had total coronary occlusion, and one had subocclusion of the vessel corresponding to the ECG site of infarction. Intracoronary nitrogly...

journal_title：American heart journal

authors： Cowley MJ,Hastillo A,Vetrovec GW,Hess ML

更新日期：1981-12-01 00:00:00

abstract：:Ambulatory ECG recordings were obtained from 313 consecutive, totally symptom-free male subjects on whom cardiac catheterization was subsequently performed for occupational reasons. These recordings were examined for ventricular ectopy and the results were studied in relation to the findings on selective coronary angi...

journal_title：American heart journal

authors： Batchelor AJ,Kruyer WB,Hickman JR Jr

更新日期：1989-06-01 00:00:00

abstract：:The effects of amiodarone on delayed afterdepolarization (DAD) and triggered automaticity induced by low potassium (0.5 mEq/L) were evaluated on isolated rabbit right ventricular muscles, by means of standard microelectrode techniques. Triggered automaticity was induced in 6 of 10 muscles in the control group, in four...

journal_title：American heart journal

authors： Ohta M,Karagueuzian HS,Mandel WJ,Peter T

更新日期：1987-02-01 00:00:00

abstract：:Salient clinical, hemodynamic, angiocardiographic, and pathologic findings are presented in 100 patients with truncus arteriosus communis, 79 of whom were studied at autopsy. In this study of typical truncus, all had a ventricular septal defect (type A). Truncus with a partially formed aorticopulmonary septum (type A1...

journal_title：American heart journal

authors： Calder L,Van Praagh R,Van Praagh S,Sears WP,Corwin R,Levy A,Keith JD,Paul MH

更新日期：1976-07-01 00:00:00

abstract：:To compare the effects of two thrombolytic agents, streptokinase and recombinant tissue-type plasminogen activator (rTPA) with early heparinization, on left ventricular function, coronary patency and reinfarction rates, bleeding complications, and short- and long-term mortality, we studied 122 patients with acute myoc...

journal_title：American heart journal

authors： Cherng WJ,Chiang CW,Kuo CT,Lee CP,Lee YS

更新日期：1992-04-01 00:00:00

abstract：:The incidence of cardiac events in Japanese men (mean age 54 +/- 10 years) with atypical or nonanginal chest pain was assessed prospectively. Three groups of patients, those with typical angina (TA; n = 134), those with atypical angina (AA; n = 192), and those with nonanginal chest pain (NA; n = 311) were studied with...

journal_title：American heart journal

authors： Sato I,Nishijima H,Matsumura N,Nishida M,Okita K,Yasuda H

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:The Gly16 beta(2)-adrenergic receptor (beta(2)AR) polymorphism is a common variant of the beta(2)AR that displays depressed function caused by enhanced receptor downregulation in vitro compared with the Arg16 receptor. METHODS AND RESULTS:We studied 20 healthy, normotensive, nonsmoking white individuals who...

journal_title：American heart journal

authors： Hoit BD,Suresh DP,Craft L,Walsh RA,Liggett SB

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:The ODYSSEY COMBO I study (http://clinicaltrials.gov/show/NCT01644175) evaluated efficacy and safety of alirocumab as add-on therapy to stable maximally tolerated daily statin with or without other lipid-lowering therapy in high cardiovascular risk patients with suboptimally controlled hypercholesterolemia. ...

journal_title：American heart journal

authors： Kereiakes DJ,Robinson JG,Cannon CP,Lorenzato C,Pordy R,Chaudhari U,Colhoun HM

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Circulating mediators, including thromboxane A2, the vasoconstrictor, platelet aggregant, and smooth muscle mitogen, may contribute to the progression of vascular narrowing in primary pulmonary hypertension (PPH). METHODS:To further understand the contribution of thromboxane and to provide novel therapy for...

journal_title：American heart journal

authors： Langleben D,Christman BW,Barst RJ,Dias VC,Galiè N,Higenbottam TW,Kneussl M,Korducki L,Naeije R,Riedel A,Simonneau G,Hirsch AM,Rich S,Robbins IM,Oudiz R,McGoon MD,Badesch DB,Levy RD,Mehta S,Seeger W,Solèr M

更新日期：2002-05-01 00:00:00