The effect of Aliskiren on exercise capacity in older patients with heart failure and preserved ejection fraction: A randomized, placebo-controlled, double-blind trial.

abstract：:Chronic exposure to fine particulate matter (PM2.5) is accepted as a causal risk factor for coronary heart disease (CHD). However, most of the evidence for this hypothesis is based upon cohort studies in whites, comprised of either only males or females who live in urban areas. It is possible that many estimates of th...

journal_title：American heart journal

authors： Loop MS,McClure LA,Levitan EB,Al-Hamdan MZ,Crosson WL,Safford MM

更新日期：2018-03-01 00:00:00

abstract：:The effect of the reperfusion on myocardial infarction has been studied in the rat in order to assess the possible reversibility of myocardial damage. The present study deals with reperfusion of experimental myocardial infarction in the rat. Two groups of animals were compared: one was subjected to permanent ischemia ...

journal_title：American heart journal

authors： Deloche A,Fabiani JN,Camilleri JP,Relland J,Joseph D,Carpentier A,Dubost C

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:The APEX trial assessed the safety and efficacy of extended-duration thromboprophylaxis using betrixaban versus standard dosing of enoxaparin among hospitalized, acutely ill medical patients. The 80-mg betrixaban dose was halved to 40 mg among subjects with severe renal insufficiency and those receiving a co...

journal_title：American heart journal

authors： Gibson CM,Halaby R,Korjian S,Daaboul Y,Arbetter DF,Yee MK,Goldhaber SZ,Hull R,Hernandez AF,Lu SP,Bandman O,Leeds JM,Gold A,Harrington RA,Cohen AT,APEX Investigators.

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Patients with an implantable cardioverter defibrillator (ICD) are at increased risk of anxiety disorders. In turn, anxiety has been identified as a precipitant of ventricular arrhythmias. Anxiety may in part be attributed to concerns about the ICD firing, but the relationship between ICD concerns, psychologi...

journal_title：American heart journal

authors： Pedersen SS,van Domburg RT,Theuns DA,Jordaens L,Erdman RA

更新日期：2005-04-01 00:00:00

abstract：:A case of tricuspid atresia with unusual echocardiographic findings is presented. The echocardiogram was successful in defining great artery interrelationships, ventricular looping, and cavity sizes. An echo pattern resembling the motion of a small tricuspid valve was observed; this was proven to be spurious at cathet...

journal_title：American heart journal

authors： Silverman NH,Payot M,Stanger P

更新日期：1978-06-01 00:00:00

abstract：:We tested whether overload of the two ventricles may be associated with a preponderance of interventricular septum in patients with high blood pressure. The rationale is that the septum is shared by the greater and lesser circulation and that in hypertension the latter shows the same qualitative hemodynamic alteration...

journal_title：American heart journal

authors： Fiorentini C,Galli C,Tamborini G,Moruzzi P,Berti M,Riva S,Guazzi MD

更新日期：1988-08-01 00:00:00

abstract：:In this study we have performed human leukocyte antigen (HLA)-A and B typing on nine patients with hypertrophic cardiomyopathy (HCM) and their relatives. Four patients had relatives who also had the disease. HLA typing of the familial form of HCM revealed a very close association of a given HLA-A,B haplotype with the ...

journal_title：American heart journal

authors： Kishimoto C,Kaburagi T,Takayama S,Yokoyama S,Hanyu I,Takatsu Y,Tomimoto K

更新日期：1983-06-01 00:00:00

abstract：:We studied 56 right ventricular papillary muscles isolated from cats to determine whether the direct mechanical effects of contrast media are due to their pharmacologic action or to the hyperosmolality caused by them. A 10% solution of Renografin-76 abruptly decreased force 22% below control, then slowly increased it ...

journal_title：American heart journal

authors： Chuck LH,Refsum H,Rouleau JL,Mathey D,Sievers RE,Parmley WW

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Automated implantable cardioverter-defibrillators (ICDs) have become standard therapy for patients at high risk for sudden cardiac death. Linked data allow examination of trends in use and long-term survival after ICD implantation in an adult population. METHODS:Linked state-wide person-based data on hospit...

journal_title：American heart journal

authors： Bradshaw PJ,Stobie P,Briffa T,Hobbs MS

更新日期：2013-05-01 00:00:00

abstract：:To test alterations in plasma potassium and magnesium levels with maximal exercise, 15 sedentary, healthy men (mean age 29 years) participated in a double-blind crossover study for 11 weeks with propranolol, atenolol, and placebo. Maximal exercise tests were done at baseline and after placebo and beta-blockade phases....

journal_title：American heart journal

authors： Fletcher GF,Sweeney ME,Fletcher BJ

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Evidence from numerous studies of coronary angiography show differences between observers' assessments of 15% to 45%. The implication of this variation is serious: If readings are erroneous, some patients will undergo revascularization procedures unnecessarily and others will be denied an essential treatment...

journal_title：American heart journal

authors： Leape LL,Park RE,Bashore TM,Harrison JK,Davidson CJ,Brook RH

更新日期：2000-01-01 00:00:00

abstract：:The purpose of this study was to assess the recovery of the left ventricular pressure (PLV), and the incidence and type of arrhythmias after effective low-dose defibrillation (Imax = 18-70 A) in healthy hearts and in hearts with acute myocardial infarction (AMI) in the intact dog. In fifteen dogs 84 episodes of fibril...

journal_title：American heart journal

authors： Geuze RH,de Vente J

更新日期：1983-08-01 00:00:00

abstract：:It has been shown that brief episodes of myocardial ischemia can render the heart more resistant to a prolonged subsequent ischemic episode. This phenomenon, called "preconditioning," has been described in human beings during coronary angioplasty with the use of clinical, electrocardiographic (ECG), or metabolic param...

journal_title：American heart journal

authors： Eltchaninoff H,Cribier A,Tron C,Derumeaux G,Koning R,Hecketsweiller B,Letac B

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To determine whether peripheral arterial disease is associated with high circulating levels of pro-inflammatory cytokines, independent of confounders. METHODS:Participants were 955 men and women aged 60 years and older representative of the population in 2 Italian communities (107 with peripheral arterial di...

journal_title：American heart journal

authors： McDermott MM,Guralnik JM,Corsi A,Albay M,Macchi C,Bandinelli S,Ferrucci L

更新日期：2005-08-01 00:00:00

abstract：:Fifty adult men with mild to moderate hypertension were recruited to participate in a double-blind crossover study. Each subject received 14 days of drug treatment and 14 days of placebo treatment (random order). Half the subjects were assigned to a metoprolol (150 mg/day) vs placebo treatment regimen and half to an a...

journal_title：American heart journal

authors： Streufert S,DePadova A,McGlynn T,Pogash R,Piasecki M

更新日期：1988-07-01 00:00:00

abstract：:Major cardiovascular risk factors, such as hypertension, hyperlipidemia, and diabetes, often cluster in the same individuals. It has been claimed that obesity, hyperinsulinemia, insulin resistance, and a deranged intracellular handling of ions have pathogenetic importance in the development of this metabolic syndrome....

journal_title：American heart journal

authors： Lind L,Lithell H

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Half of patients with hypertension have poor blood pressure (BP) control. Recent models for treating hypertension have integrated disease monitoring and telephone-based interventions delivered in patients' homes. This study evaluated the costs of the Hypertension Intervention Nurse Telemedicine Study (HINTS)...

journal_title：American heart journal

authors： Wang V,Smith VA,Bosworth HB,Oddone EZ,Olsen MK,McCant F,Powers BJ,Van Houtven CH

更新日期：2012-06-01 00:00:00

abstract：:To investigate the influence of intrinsic limb vasodilator capacity on exercise performance, limb reactive hyperemic flows and their relations to exercise capacity during upright bicycle exercise were examined in 52 patients with recent myocardial infarction. Reactive hyperemic flow was measured in the forearm and the...

journal_title：American heart journal

authors： Hattori T,Sumimoto T,Yuasa F,Kaida M,Jikuhara T,Hikosaka M,Sugiura T,Iwasaka T

更新日期：1996-09-01 00:00:00

abstract：:Plasma catecholamine levels were determined in 26 cases of uncomplicated myocardial infarction within 24 hours of onset of acute chest pain. Blood samples were collected at time of entry and at 4-hour intervals during the 48 hours following admission. Average values of plasma catecholamines within 1 hour of onset of p...

journal_title：American heart journal

authors： Nadeau RA,de Champlain J

更新日期：1979-11-01 00:00:00

abstract：:Adenosine infusion is accompanied by increases in coronary blood flow and myocardial blood volume. Myocardial blood volume may produce changes in diastolic left ventricular (LV) performance by increasing myocardial turgor. Diastolic dysfunction may also be the result of myocardial ischemia. The relation between change...

journal_title：American heart journal

authors： Ren JF,Pancholy SB,Kegel JG,Lighty GW Jr,Heo J,Iskandrian AS

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:A large proportion of patients with heart failure (HF) have a large and poorly contracting left ventricle. The noninvasive recognition of the ischemic etiology of such patients is difficult, and for this purpose, usually patients undergo coronary angiography. It has been shown that cardiovascular magnetic re...

journal_title：American heart journal

authors： Casolo G,Minneci S,Manta R,Sulla A,Del Meglio J,Rega L,Gensini G

更新日期：2006-01-01 00:00:00

abstract：:Evaluation of pericardial effusion was attempted with computed tomography in 11 patients. The volume and distribution of pericardial fluid were assessed with satisfactory resolution and the nature of the fluid was estimated by the difference in x-ray transparency (CT numbers). The volume of pericardial fluid calculate...

journal_title：American heart journal

authors： Tomoda H,Hoshiai M,Furuya H,Oeda Y,Matsumoto S,Tanabe T,Tamachi H,Sasamoto H,Koide S,Kuribayashi S,Matsuyama S

更新日期：1980-06-01 00:00:00

abstract：OBJECTIVES:Impedance monitoring has been proposed as a method to assess the adequacy of tissue heating during catheter ablation procedures. The purpose of this study was to evaluate the relation among initial impedance, fall in impedance, and electrode temperature during catheter ablation procedures. METHODS AND RESUL...

journal_title：American heart journal

authors： Nsah E,Berger R,Rosenthal L,Hui R,Ramza B,Jumrussirikul P,Lawrence JH,Tomaselli G,Kass D,Calkins H

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Studies document better survival in heart failure patients with decreased left ventricular ejection fraction (EF) and higher body mass index (BMI; kg/m(2)) compared to those with a lower BMI. However, it is unknown if this "obesity paradox" applies to heart failure patients with preserved EF or if it extends...

journal_title：American heart journal

authors： Kapoor JR,Heidenreich PA

更新日期：2010-01-01 00:00:00

abstract：:Cost-effectiveness analyses are routinely performed to determine whether the additional cost of a novel therapy is balanced by additional effectiveness. The definitions of costs and effects involve a variety of assumptions, both in general economic terms and with regard to the specific medical setting under considerat...

journal_title：American heart journal

authors： van Hout BA,Bowman L,Zelinger DJ,Simoons ML

更新日期：1998-04-01 00:00:00

abstract：:To determine which method of surgical therapy might be optimal for patients with anomalous left coronary artery from the pulmonary artery (ALCAPA), a follow-up study was performed. Twenty-nine teenagers and adults who had ALCAPA diagnosed during life at age 13 years or older were identified mainly by literature search...

journal_title：American heart journal

authors： Wilson CL,Dlabal PW,McGuire SA

更新日期：1979-10-01 00:00:00

abstract：:Blood platelets play essential roles in normal coagulation and in coronary atherosclerotic disease and its complications. Various antiplatelet therapies, including aspirin, ticlopidine, and dipyridamole, have been developed for use in patients with known coronary artery artery disease to prevent ischemic complications...

journal_title：American heart journal

authors： Frishman WH,Burns B,Atac B,Alturk N,Altajar B,Lerrick K

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Depressive symptoms in patients with heart failure (HF) are common and might be associated with inflammation. No studies have examined both the cross-sectional and prospective association between inflammation and depressive symptoms in patients with HF with adequate correction for disease severity. The aim o...

journal_title：American heart journal

authors： Johansson P,Lesman-Leegte I,Svensson E,Voors A,van Veldhuisen DJ,Jaarsma T

更新日期：2011-06-01 00:00:00

abstract：:We performed a chronologic investigation of left (LV) and right (RV) ventricular myosin ATPase activity and hemodynamics in newborn lambs. We found an elevation in myosin ATPase activity for the LV, which was achieved by 6 to 8 weeks of age and which correlated directly with increasing ventricular stroke work. Myosin ...

journal_title：American heart journal

authors： Riemenschneider TA,Brenner RA,Wikman-Coffelt J,Mason DT

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Patients with kidney failure have a heavy burden of coronary artery disease. The results of preventive, diagnostic, and therapeutic measures developed in nonuremic populations cannot automatically be extrapolated to this unique group of patients. METHODS AND RESULTS:Articles were reviewed if they contained ...

journal_title：American heart journal

authors： Vaitkus PT

更新日期：2000-06-01 00:00:00