Peripheral hemodynamic effects of captopril in patients with congestive heart failure.

abstract：BACKGROUND:The 2020 American Heart Association Impact Goal aims to improve cardiovascular health of all Americans by 20% while reducing deaths from cardiovascular disease and stroke by 20%. A large step toward this goal would be to better understand and take advantage of the significant intersection between behavior an...

journal_title：American heart journal

authors： Bansilal S,Vedanthan R,Kovacic JC,Soto AV,Latina J,Björkegren JLM,Jaslow R,Santana M,Sartori S,Giannarelli C,Mani V,Hajjar R,Schadt E,Kasarskis A,Fayad ZA,Fuster V

更新日期：2017-05-01 00:00:00

abstract：:Clinical and experimental evidence suggest that sympathoadrenal activation contributes to mortality in patients with ischemic heart disease. To determine the level of sympathoadrenal activation in the very early phase of acute myocardial infarction (AMI) and to determine if location of infarction (anterior versus infe...

journal_title：American heart journal

authors： Karlsberg RP,Cryer PE,Roberts R

更新日期：1981-07-01 00:00:00

abstract：:Since many patients with chest pain cannot exercise adequately, an alternative stress would be useful to evaluate coronary reserve. We studied the physiologic responses to epinephrine to assess its potential. We report on 39 patients with chest pain. Doses from 0.03 to 0.30 micrograms/kg/min were administered intraven...

journal_title：American heart journal

authors： Schechter E,Wilson MF,Kong YS

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Guidelines recommend consideration of cardiac biomarker measurement after elective percutaneous coronary intervention (PCI), especially with complex cases or complicated procedures. However, the long-term prognostic implications of biomarker measurement after elective PCI have not been well characterized in ...

journal_title：American heart journal

authors： Wang TY,McCoy LA,Messenger JC,Neely ML,Ho KK,Roe MT,Anderson HV

更新日期：2013-11-01 00:00:00

abstract：:Plasma levels of endothelin-1 are elevated in patients with chronic heart failure; however, it is unknown whether changes in plasma endothelin-1 levels accurately reflect clinical response to therapy in these patients. To determine this, we measured plasma endothelin-1 in addition to functional, hemodynamic, and other...

journal_title：American heart journal

authors： Krum H,Gu A,Wilshire-Clement M,Sackner-Bernstein J,Goldsmith R,Medina N,Yushak M,Miller M,Packer M

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Dobutamine and exercise echocardiography are accepted as tests of comparable efficacy for the diagnosis of coronary artery disease. Although dobutamine has been classified as "exercise simulating," the mechanisms of ischemia with dobutamine and exercise have not been well studied. This study sought to compar...

journal_title：American heart journal

authors： Mairesse GH,Vanoverschelde JL,Robert A,Climov D,Detry JM,Marwick TH

更新日期：1998-07-01 00:00:00

abstract：:Calcium channel blockers and central alpha-agonists are among the classes of antihypertensive drugs that yield the most favorable overall effects on risk factors for hypertension-related end-organ damage. An open-label prospective trial in 42 patients with a mean baseline blood pressure of 144/102 mm Hg sought to asse...

journal_title：American heart journal

authors： Houston MC,Hays L

更新日期：1993-10-01 00:00:00

abstract：:The objective of the current editorial is to introduce a new concept ("maimed myocardium") that we believe describes more accurately the incomplete, delayed recovery of LV function that may occur late after reperfusion after AMI. It has been demonstrated previously that myocardium remains viable for a prolonged period...

journal_title：American heart journal

authors： Boden WE,Brooks WW,Conrad CH,Bing OH,Hood WB Jr

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:The 6-minute walk test is a submaximal exercise test that is widely used as an outcomes measure in clinical trials and cardiopulmonary rehabilitation. An initial learning effect with repeated administration is well documented, but it is unknown whether this learning effect persists with time. METHODS:This s...

journal_title：American heart journal

authors： Wu G,Sanderson B,Bittner V

更新日期：2003-07-01 00:00:00

abstract：:Atherosclerosis and its vascular sequela are responsible for considerable morbidity and mortality rates. Several risk factors have been implicated in the pathogenesis of atherosclerosis, and the search for other risk factors continues on the medical horizon. Renin-angiotensin system (RAS), a multienzyme, multilocale a...

journal_title：American heart journal

authors： Malik FS,Lavie CJ,Mehra MR,Milani RV,Re RN

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:In patients with severe pulmonary hypertension (PH), right ventricular function is a main determinant of clinical stability and outcome. Supraventricular tachyarrhythmias (SVTs) may compromise cardiac function and threaten prognosis in patients with PH, but the incidence and clinical relevance of SVTs in PH ...

journal_title：American heart journal

authors： Tongers J,Schwerdtfeger B,Klein G,Kempf T,Schaefer A,Knapp JM,Niehaus M,Korte T,Hoeper MM

更新日期：2007-01-01 00:00:00

abstract：:We compared the pauses that followed the spontaneous termination of supraventricular tachyarrhythmias with the pauses that followed the cessation of atrial overdrive pacing in 21 patients. In 10 patients with abnormal sinus node function and in 11 patients with normal sinus node function we recorded the spontaneous te...

journal_title：American heart journal

authors： Gang ES,Reiffel JA,Livelli FD Jr,Bigger JT Jr

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Comparing the dose-response of a new drug to that of a previously studied drug can aid in understanding their relative potencies. Two dose-finding studies addressed the effect of a new drug, rosuvastatin, on its ability to decrease low-density lipoprotein cholesterol (LDL-C) levels. One of these studies incl...

journal_title：American heart journal

authors： Berry DA,Berry SM,McKellar J,Pearson TA

更新日期：2003-06-01 00:00:00

abstract：:The electrocardiographic QT interval, with a wide variety of practical and theoretic applications in medicine, pharmacology, and cardiology, is critically dependent on heart rate as expressed by cycle length (RR). To account for this and permit intraindividual and interindividual comparisons of changing QT intervals, ...

journal_title：American heart journal

authors： Spodick DH,Rifkin RD,Rajasingh MC

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:The acute benefits of platelet glycoprotein IIb/IIIa inhibitors for non-ST-segment elevation acute coronary syndromes (NSTE ACS) remain unclear. METHODS:In this pilot trial, 311 patients with NSTE ACS were randomly assigned in the emergency department to double-blinded therapy with eptifibatide or placebo f...

journal_title：American heart journal

authors： Roe MT,Christenson RH,Ohman EM,Bahr R,Fesmire FM,Storrow A,Mollod M,Peacock WF,Rosenblatt JA,Yang H,Fraulo ES,Hoekstra JW,Gibler WB,EARLY Investigators.,Emergency Medicine Cardiac Research and Education Group.

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Current acetylsalicylic acid (ASA) dosing algorithms for the prevention of secondary thrombotic events in acute coronary syndrome (ACS) patients are inconsistent and lack sufficient data support. METHODS:We performed a systematic review of the literature for studies that assessed clinical outcomes in patien...

journal_title：American heart journal

authors： Berger JS,Sallum RH,Katona B,Maya J,Ranganathan G,Xu Y,Mwamburi M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Heart failure (HF) is one of the leading causes of morbidity and mortality among Americans. Despite increased interest in end-of-life care, the implications of do-not-resuscitate (DNR) orders in acutely ill patients with HF remain unclear. The goals of this observational study were to describe the use of DNR...

journal_title：American heart journal

authors： Chen JL,Sosnov J,Lessard D,Goldberg RJ

更新日期：2008-07-01 00:00:00

abstract：:The systemic and renal hemodyanmic effects of bupicomide were studied in 10 male patients with uncomplicated essential hypertension of moderate severity. Bupicomide significantly reduced systolic, diastolic, and mean arterial pressure and peripheral vascular resistance and this hypotensive effect was associated with a...

journal_title：American heart journal

authors： Chrysant SG,Adamopoulos P,Tsuchiya M,Frohlich ED

更新日期：1976-09-01 00:00:00

abstract：:Coronary arterial stenosis of varying severity and length were created in open-chest dogs. The reactive hyperemic responses (RHR) to 15 second occlusions were used to produce flow increases and judge the physiological significance of the narrowings. RHR are sensitive indices of functional impairment when resting flow ...

journal_title：American heart journal

authors： Hillis WS,Friesinger GC

更新日期：1976-12-01 00:00:00

abstract：OBJECTIVE:Racial differences in cardiovascular mortality among women remain largely unexplained. Preliminary data suggest that African American and Caucasian differences in endothelial function may parallel differential cardiovascular disease (CVD) risk in women. To further study differences in endothelial function bet...

journal_title：American heart journal

authors： Loehr LR,Espeland MA,Sutton-Tyrrell K,Burke GL,Crouse JR 3rd,Herrington DM

更新日期：2004-10-01 00:00:00

abstract：:The occurrence of thrombotic events is central to the course of polycythemia vera. Myocardial, cerebral, peripheral, and pulmonary infarctions are frequent and are consequences of throbmoses in small and medium caliber arteries. Thrombosis in large caliber arteries is a rare event. Thrombosis within the chambers of th...

journal_title：American heart journal

authors： Ali M,Fayemi AO,Malcolm D,Braun EV

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:During daytime working hours, outcomes may be worse when percutaneous coronary intervention (PCI) is performed later in the day because of operator fatigue and differences in process of care. METHODS:Using the APPROACH database, we analyzed 2,492 consecutive nonurgent PCI procedures performed during working...

journal_title：American heart journal

authors： Cantor WJ,Strauss BH,Graham MM,Southern DA,Woo K,Tyrrell B,Knudtson M,Ghali WA

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Although cross-sectional studies have identified lifestyle factors associated with high-density lipoprotein cholesterol (HDL-C), no studies have examined the association between changes in lifestyle factors and long-term changes in HDL-C. METHODS:We examined the association between changes in lifestyle fact...

journal_title：American heart journal

authors： Rahilly-Tierney C,Sesso HD,Djoussé L,Gaziano JM

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:In the United States, there continues to be debate about whether certain types of hospitals deliver improved patient outcomes. We sought to assess the association between hospital organizational characteristics and in-hospital outcomes for percutaneous coronary intervention (PCI). METHODS:Retrospective anal...

journal_title：American heart journal

authors： Cram P,House JA,Messenger JC,Piana RN,Horwitz PA,Spertus JA

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Single center studies using serial cerebral diffusion-weighted magnetic resonance imaging in patients having cardiac catheterization have suggested that cerebral microembolism might be responsible for silent cerebral infarct (SCI) as high as 15% to 22%. We evaluated in a multicenter trial the incidence of SC...

journal_title：American heart journal

authors： Hamon M,Lipiecki J,Carrié D,Burzotta F,Durel N,Coutance G,Boudou N,Colosimo C,Trani C,Dumonteil N,Morello R,Viader F,Claise B,Hamon M

更新日期：2012-10-01 00:00:00

abstract：:In order to correlate the antiarrhythmic and electrophysiological effects of disopyramide phosphate during acute myocardial ischemia, we performed experiments in 17 mongrel dogs. Refractory periods obtained by the extrastimulus method and conduction times recorded from local electrograms were determined in potentially...

journal_title：American heart journal

authors： Levites R,Anderson GJ

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Circulating mediators, including thromboxane A2, the vasoconstrictor, platelet aggregant, and smooth muscle mitogen, may contribute to the progression of vascular narrowing in primary pulmonary hypertension (PPH). METHODS:To further understand the contribution of thromboxane and to provide novel therapy for...

journal_title：American heart journal

authors： Langleben D,Christman BW,Barst RJ,Dias VC,Galiè N,Higenbottam TW,Kneussl M,Korducki L,Naeije R,Riedel A,Simonneau G,Hirsch AM,Rich S,Robbins IM,Oudiz R,McGoon MD,Badesch DB,Levy RD,Mehta S,Seeger W,Solèr M

更新日期：2002-05-01 00:00:00

abstract：:ECGs taken from four patients with concealed atrial bigeminy were analyzed to find the mechanisms of disappearance and reappearance of extrasystoles. Observations in three patients showing the classic form of concealed bigeminy suggest that when the extrasystole disappeared, the first sinus impulse after the last mani...

journal_title：American heart journal

authors： Kinoshita S,Kato Y,Nakagawa K,Yasukouchi T

更新日期：1984-05-01 00:00:00

abstract：:The effect of participation in cardiac rehabilitation on medical costs was determined by measuring hospitalization charges for cardiac admissions over a 3-year period in 580 post-coronary event patients (58% after coronary bypass surgery, 42% after myocardial infarction), of whom 230 entered a cardiac rehabilitation p...

journal_title：American heart journal

authors： Ades PA,Huang D,Weaver SO

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Peak exercise oxygen consumption (peak VO2) is an important discriminator of survival in patients with systolic heart failure and is used to select ambulatory patients for transplantation. The major trials assessing the relationship between peak VO2 and survival have used a variety of low-level exercise prot...

journal_title：American heart journal

authors： Strzelczyk TA,Cusick DA,Pfeifer PB,Bondmass MD,Quigg RJ

更新日期：2001-09-01 00:00:00