Reactive hyperemia: an index of the significance of coronary stenoses.

abstract：BACKGROUND:We evaluated ethnic differences in the 10-year risk of myocardial infarction or coronary death derived from Framingham risk equation and in a composite measure of emerging cardiovascular disease risk factors in women and whether statistical adjustments for educational attainment, geographic location, and lif...

journal_title：American heart journal

authors： Matthews KA,Sowers MF,Derby CA,Stein E,Miracle-McMahill H,Crawford SL,Pasternak RC

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Coronary heart disease (CHD) in women is strongly associated with estrogen deprivation. For example, risk for CHD increases dramatically after menopause. However, the role of hormone replacement therapy (HRT) in CHD prevention currently is unresolved. To better understand CHD in women, the precise mechanisms...

journal_title：American heart journal

authors： McCubbin JA,Helfer SG,Switzer FS 3rd,Price TM

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:No-reflow after primary percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) is associated with poor prognosis. Endothelin-1 (ET-1) is a potent endothelium-derived vasoconstrictor that might aggravate reperfusion injury. The aim of our study was to assess the relationship be...

journal_title：American heart journal

authors： Eitel I,Nowak M,Stehl C,Adams V,Fuernau G,Hildebrand L,Desch S,Schuler G,Thiele H

更新日期：2010-05-01 00:00:00

abstract：:A-II exerts its activity on various target tissues by binding to its receptors. The discovery of local RASs and A-II receptors within various tissues has generated interest in the clinical usefulness of RAS inhibition by directly blocking the action of A-II at the receptor level. Different A-II receptor subtypes have ...

journal_title：American heart journal

authors： Kang PM,Landau AJ,Eberhardt RT,Frishman WH

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:There are limited data regarding the clinical correlates and prognostic significance of echocardiographically defined mitral regurgitation (MR) early after acute myocardial infarction (MI). The current study addressed these issues. METHODS:Seven hundred thirty-seven patients with acute MI who underwent tran...

journal_title：American heart journal

authors： Hillis GS,Møller JE,Pellikka PA,Bell MR,Casaclang-Verzosa GC,Oh JK

更新日期：2005-12-01 00:00:00

abstract：:The present study refers to six patients in whom an A-V reciprocal rhythm could be documented; in four cases it took the form of sustained tachycardia. None of the patients showed any ECG feature of ventricular pre-excitation (PR interval of more than 0.12 sec. and normal QRS configuration). The extrastimulus method s...

journal_title：American heart journal

authors： Touboul P,Huerta F,Porte J,Delahaye JP

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:The Gly16 beta(2)-adrenergic receptor (beta(2)AR) polymorphism is a common variant of the beta(2)AR that displays depressed function caused by enhanced receptor downregulation in vitro compared with the Arg16 receptor. METHODS AND RESULTS:We studied 20 healthy, normotensive, nonsmoking white individuals who...

journal_title：American heart journal

authors： Hoit BD,Suresh DP,Craft L,Walsh RA,Liggett SB

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Cardiac pacing can be challenging after a Fontan operation, and limited data exist regarding pacing in adult Fontan patients. The objectives of our study were to determine risk factors for pacing and occurrence of device-related complications (DRCs) and pacemaker reinterventions. METHODS:We performed a retr...

journal_title：American heart journal

authors： Egbe AC,Huntley GD,Connolly HM,Ammash NM,Deshmukh AJ,Khan AR,Said SM,Akintoye E,Warnes CA,Kapa S

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:New-onset postoperative atrial fibrillation (POAF) is associated with poor short- and long-term outcomes after isolated coronary artery bypass graft (CABG). This study evaluated whether new-onset POAF is independently associated with long-term (>1 year) atrial fibrillation (AF) and mortality. METHODS:Among ...

journal_title：American heart journal

authors： Lee SH,Kang DR,Uhm JS,Shim J,Sung JH,Kim JY,Pak HN,Lee MH,Joung B

更新日期：2014-04-01 00:00:00

abstract：:The aim of this study was to examine the effect of ventricular fibrillation and a subsequent defibrillation shock on ventricular excitability and refractoriness in human beings. We studied 16 consecutive patients with implantable cardioverter-defibrillators undergoing follow-up studies. The pre- and post-shock pacing ...

journal_title：American heart journal

authors： Yu JC,Lauer MR,Young C,Liem B,Peterson J,Ottoboni L,Sung RJ

更新日期：1996-06-01 00:00:00

abstract：:This prospective study evaluated the accuracy of phase analysis of scintigraphic imaging in defining the site of earliest ventricular activation in pediatric patients with electrophysiologic disorders. Twenty patients (10.8 +/- 5.5 years) with preexcitation (n = 16) or ventricular tachycardia (VT) (n = 4) were indepen...

journal_title：American heart journal

authors： Silka MJ,Chelsky R,Kron J,Wilson RA

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:The effect of age on diagnostic and prognostic performance of high-sensitivity cardiac troponin T (hs-cTnT) has not been addressed adequately, so far. METHODS:High-sensitivity cardiac troponin T was measured serially in patients with acute symptoms presenting to our emergency department. We tested the diagn...

journal_title：American heart journal

authors： Normann J,Mueller M,Biener M,Vafaie M,Katus HA,Giannitsis E

更新日期：2012-11-01 00:00:00

abstract：:We have explored the systolic time intervals of 52 patients with angina pectoris at the time of their hospitalization in our wards. Our results are in close agreement with published data, essentially indicating prolongation of the preejection time and shortening of the ejection time. These alterations of systolic time...

journal_title：American heart journal

authors： Randazzo A,Sardella F,Martinotti R,Daffara G,Parziale M,Cremonesi G

更新日期：1983-05-01 00:00:00

abstract：:We performed a chronologic investigation of left (LV) and right (RV) ventricular myosin ATPase activity and hemodynamics in newborn lambs. We found an elevation in myosin ATPase activity for the LV, which was achieved by 6 to 8 weeks of age and which correlated directly with increasing ventricular stroke work. Myosin ...

journal_title：American heart journal

authors： Riemenschneider TA,Brenner RA,Wikman-Coffelt J,Mason DT

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Multidisciplinary disease management programs (MDMP) have demonstrated reduced hospitalizations in motivated pretransplant heart failure populations, but little is known about their effectiveness in largely indigent patients who are not transplant candidates. METHODS AND RESULTS:We studied 35 patients with ...

journal_title：American heart journal

authors： O'Connell AM,Crawford MH,Abrams J

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:In recent reports, human toll-like receptor (TLR) 8 mediates the antiviral response by recognizing single-stranded RNA. The inflammatory response against enteroviral (EV) RNA replication may play an important role in dilated cardiomyopathy (DCM). The purpose of this study was to determine whether TLR8 was ex...

journal_title：American heart journal

authors： Satoh M,Akatsu T,Ishikawa Y,Minami Y,Takahashi Y,Nakamura M

更新日期：2007-09-01 00:00:00

abstract：:Women with coronary artery disease are less likely to undergo percutaneous transluminal coronary angioplasty (PTCA) because of the potential referral bias in favor of men with coronary artery disease in the use of invasive diagnostic procedures and interventions. This difference may represent a sex bias in the deliver...

journal_title：American heart journal

authors： Hussain KM,Estrada AQ,Kogan A,Dadkhah S,Foschi A

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:It is unclear whether fibrinogen predicts cardiovascular events independently of echocardiographic cardiovascular abnormalities and traditional risk factors. METHODS:We studied 2671 American Indians who participated in the second Strong Heart Study examination (1993-1995) and were observed for an average of...

journal_title：American heart journal

authors： Palmieri V,Celentano A,Roman MJ,de Simone G,Best L,Lewis MR,Robbins DC,Fabsitz RR,Howard BV,Devereux RB,Strong Heart Study.

更新日期：2003-03-01 00:00:00

abstract：:Patients with impaired glucose tolerance (IGT) have increased risk for developing type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Lifestyle modification and medication can prevent or delay progression to diabetes (PD), but whether such interventions also reduce the risk of CVD has not been rigorously...

journal_title：American heart journal

authors： Califf RM,Boolell M,Haffner SM,Bethel M,McMurray J,Duggal A,Holman RR,NAVIGATOR Study Group.

更新日期：2008-10-01 00:00:00

abstract：:Cross-sectional echocardiography identified two abnormal patterns of mitral valve closure in 14 patients with mitral regurgitation due to papillary muscle dysfunction: (1) in three patients with an akinetic inferior-posterior wall but normal cavity size, papillary muscle fibrosis was associated with late systolic mitr...

journal_title：American heart journal

authors： Ogawa S,Hubbard FE,Mardelli TJ,Dreifus LS

更新日期：1979-03-01 00:00:00

abstract：:Flow beyond a stenotic aortic valve (AS) is dynamically complex. Numerous hydraulic studies have demonstrated that at least four well-known major flow areas occur distal to a stenotic valve. These include a jet, an area alongside the jet (the parajet), an area of flow disturbance, and an area in which disturbed flow a...

journal_title：American heart journal

authors： Goldberg SJ,Kececioglu-Draelos Z,Sahn DJ,Valdes-Cruz LM,Allen HD

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Heparin is ubiquitously used in cardiac catheterization but predisposes to the development of heparin-induced thrombocytopenia. The objective was to examine prospectively the prevalence of anti-platelet factor 4 (PF4)/heparin antibodies and heparin-induced thrombocytopenia in the population undergoing cardia...

journal_title：American heart journal

authors： Foo SY,Everett BM,Yeh RW,Criss D,Laposata M,Van Cott EM,Jang IK

更新日期：2006-08-01 00:00:00

abstract：:The MAPHY Study was conducted to investigate whether metoprolol, a relatively beta 1-selective beta-blocker, given as initial antihypertensive treatment, would lower cardiovascular complications of high blood pressure to a greater extent than do thiazide diuretics as initial treatment at similar blood pressure control...

journal_title：American heart journal

authors： Wikstrand J

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:In the TRACER trial, vorapaxar, a protease-activated receptor-1 antagonist, plus standard care in non-ST-segment elevation acute coronary syndrome (NSTE ACS) patients did not significantly reduce the primary composite end point but reduced a key secondary end point and significantly increased bleeding. Histo...

journal_title：American heart journal

authors： Jones WS,Tricoci P,Huang Z,Moliterno DJ,Harrington RA,Sinnaeve PR,Strony J,Van de Werf F,White HD,Held C,Armstrong PW,Aylward PE,Chen E,Patel MR,Mahaffey KW

更新日期：2014-10-01 00:00:00

abstract：:To evaluate the antiischemic effects of intravenous milrinone, 20 patients with angiographically proved coronary artery disease and stable angina were studied at rest and during exercise under control conditions and after an intravenous loading injection of milrinone (50 micrograms/kg/10 min) followed by an infusion w...

journal_title：American heart journal

authors： Mitrovic V,Stöhring R,Schlepper M

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Chronotropic incompetence and left ventricular (LV) dilatation have both been shown to be markers of an adverse cardiovascular prognosis. Chronotropic incompetence has been described in patients with symptomatic LV dilatation and dysfunction, but the effect of asymptomatic LV dilatation and hypertrophy on ex...

journal_title：American heart journal

authors： Lauer MS,Larson MG,Evans JC,Levy D

更新日期：1999-05-01 00:00:00

abstract：:Atrial depressurization time measurement by Doppler ultrasound can be used to quantify stenotic mitral valve area. In this report, we present the results of a blinded trial comparing the standard Doppler method for "pressure half-time" (A) and another Doppler method we devised (B) for measurement of atrial depressuriz...

journal_title：American heart journal

authors： Pearlman JD,Gibson RS

更新日期：1987-04-01 00:00:00

abstract：:To compare the effects of two thrombolytic agents, streptokinase and recombinant tissue-type plasminogen activator (rTPA) with early heparinization, on left ventricular function, coronary patency and reinfarction rates, bleeding complications, and short- and long-term mortality, we studied 122 patients with acute myoc...

journal_title：American heart journal

authors： Cherng WJ,Chiang CW,Kuo CT,Lee CP,Lee YS

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Prior studies regarding the effect of racial status on post-myocardial infarction (MI) in subjects with diabetes have yielded conflicting results. We evaluated the effect of diabetes status on racial differences in post-MI mortality and morbidity for a 7-year period, from 1990 through 1997. METHODS:All pati...

journal_title：American heart journal

authors： Kamalesh M,Subramanian U,Ariana A,Sawada S,Peterson E

更新日期：2005-11-01 00:00:00

abstract：:Compared with pathologic studies coronary angiography is a relatively insensitive technique to detect early atherosclerosis. Coronary angioscopy is a new technique providing direct information on luminal vessel surface. To determine whether coronary angioscopy may detect the presence of atherosclerotic disease on angi...

journal_title：American heart journal

authors： Alfonso F,Goicolea J,Hernandez R,Segovia J,Silva JC,Perez-Vizcayno MJ,Rollan MJ,Bañuelos C,Macaya C

更新日期：1995-11-01 00:00:00