Maturational changes in cardiac muscle myosin adenosine triphosphatase activity relative to hemodynamic alterations in newborn lambs.

abstract：:In 14 patients with severe congestive heart failure, the effects of captopril on the forearm circulation were evaluated with strain gauge plethysmography. Changes in plasma renin activity, angiotensin II, norepinephrine, epinephrine, bradykinin, prostaglandin E2, and 6-keto-prostaglandin F1 alpha concentrations were a...

journal_title：American heart journal

authors： Nishimura H,Kubo S,Ueyama M,Kubota J,Kawamura K

更新日期：1989-01-01 00:00:00

abstract：:Few studies have examined metabolic consequences of coronary occlusion and reperfusion using phosphorus31 nuclear magnetic resonance (31P-NMR) in an intact animal model. Accordingly, we developed a model to study serial changes in myocardial metabolism in the intact open-chest rabbit. Ten animals underwent 20 +/- 2 mi...

journal_title：American heart journal

authors： Kavanaugh KM,Aisen AM,Fechner KP,Chenevert TL,Dunham WR,Buda AJ

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVES:To define the incidence and cumulative risk of atrial fibrillation (AF) in a population-based cohort of whites and African Americans. BACKGROUND:African-Americans reportedly have a lower risk of AF than whites despite their higher exposure to AF risk factors. However, precise estimates of AF incidence in Af...

journal_title：American heart journal

authors： Alonso A,Agarwal SK,Soliman EZ,Ambrose M,Chamberlain AM,Prineas RJ,Folsom AR

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:In adults with an atrial septal defect (ASD) transcatheter closure leads to an improvement of peak oxygen uptake (VO2), but the kinetics of recovery of VO2 after maximal exercise in this patient population and the impact of transcatheter ASD closure have never been investigated. METHODS:Twenty consecutive p...

journal_title：American heart journal

authors： Giardini A,Donti A,Specchia S,Coutsoumbas G,Formigari R,Prandstraller D,Bronzetti G,Bonvicini M,Picchio FM

更新日期：2004-05-01 00:00:00

abstract：:To assess the relation between myocardial ischemia, ventricular arrhythmias (VA), and left ventricular (LV) dysfunction, we evaluated 74 patients with coronary artery disease (CAD) using radionuclide angiography (to determine the resting ejection fraction [EF]), resting thallium-201 scintigraphy (to ascertain the exte...

journal_title：American heart journal

authors： Edlin DE,Morganroth J,Iskandrian AS,Speilman SR,Horowitz LN,Kay H

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the impact of myocardial perfusion imaging (MPI) on the outcomes of death, myocardial infarction (MI), and late coronary revascularization procedures. METHODS:In patients undergoing exercise-stress MPI (January 1, 2003-March 31, 2007), we determined the impact of summe...

journal_title：American heart journal

authors： Lee DS,Verocai F,Husain M,Al Khdair D,Wang X,Freeman M,Iwanochko RM

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Limited information is available about recent trends in the incidence and death rates from atrial fibrillation (AF) complicating acute myocardial infarction (AMI). The purpose of this study was to examine the impact and trends over time of AF complicating initial AMI. METHODS:We conducted a longitudinal stu...

journal_title：American heart journal

authors： Goldberg RJ,Yarzebski J,Lessard D,Wu J,Gore JM

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:A high fasting glucose level may be a marker not only for microvascular complications, but also for macrovascular complications. We evaluated the clinical significance of a high fasting glucose level (> or =110 mg/dL), detected either at baseline or during follow-up, in the Bezafibrate Infarction Prevention ...

journal_title：American heart journal

authors： Arcavi L,Behar S,Caspi A,Reshef N,Boyko V,Knobler H

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:In patients with atrial fibrillation, incomplete adherence to anticoagulants increases risk of stroke. Non-warfarin oral anticoagulants (NOACs) are expensive; we evaluated whether higher copayments are associated with lower NOAC adherence. METHODS:Using a national claims database of commercially-insured pat...

journal_title：American heart journal

authors： Rome BN,Gagne JJ,Avorn J,Kesselheim AS

更新日期：2021-01-14 00:00:00

abstract：BACKGROUND:Current acetylsalicylic acid (ASA) dosing algorithms for the prevention of secondary thrombotic events in acute coronary syndrome (ACS) patients are inconsistent and lack sufficient data support. METHODS:We performed a systematic review of the literature for studies that assessed clinical outcomes in patien...

journal_title：American heart journal

authors： Berger JS,Sallum RH,Katona B,Maya J,Ranganathan G,Xu Y,Mwamburi M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:All patients who present to an emergency department (ED) are triaged. The ED triage score may determine when patients are seen by a physician. Half of patients with acute myocardial infarction (AMI) were given a low priority score in Ontario in 2000/2001. We assessed the appropriateness of ED triage and its ...

journal_title：American heart journal

authors： Atzema CL,Schull MJ,Austin PC,Tu JV

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Dyspnea is a complex system with multiple etiologies, including myocardial ischemia ("anginal equivalent"). Few studies have examined the utility of stress testing to detect coronary artery disease in this setting. The purpose of this study was to examine the prevalence, severity, and prognostic value of per...

journal_title：American heart journal

authors： Balaravi B,Miller TD,Hodge DO,Gibbons RJ

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Vesnarinone has yielded controversial results on morbidity in patients with congestive heart failure. We tested the hypothesis that vesnarinone may have a beneficial effect on cardiac remodeling and function. METHODS:Thirty-four patients with left ventricular ejection fraction (LVEF) <30% (17 treated with v...

journal_title：American heart journal

authors： Scherrer-Crosbie M,Cocca-Spofford D,DiSalvo TG,Semigran MJ,Dec GW,Picard MH

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Embolization of atherothrombotic material is common during percutaneous coronary intervention (PCI) in acute myocardial infarction (MI). This may lead to distal vessel occlusion resulting in impaired myocardial perfusion, which is associated with larger infarct size and increased mortality. Adj...

journal_title：American heart journal

authors： Svilaas T,van der Horst IC,Zijlstra F

更新日期：2006-03-01 00:00:00

abstract：:We evaluated electrocardiographically the acute effect of captopril in the initial treatment of malignant or severe hypertension and the findings were compared with the data obtained with diazoxide. The captopril group included seven patients treated with captopril or with a combination of diuretics. The diazoxide gro...

journal_title：American heart journal

authors： Abe I,Kawasaki T,Kawazoe N,Omae T

更新日期：1983-09-01 00:00:00

abstract：:In this overview we studied evidence for the occurrence of silent myocardial ischemia, its pathophysiologic mechanisms, and the circadian distribution of ischemic episodes. The correlation between many hemodynamic parameters and their potential as drug targets was assessed. ECG evidence of myocardial ischemia (ST segm...

journal_title：American heart journal

authors： Fox K,Mulcahy D,Keegan J,Wright C

更新日期：1989-11-01 00:00:00

abstract：:To evaluate the mechanisms involved in nitrate tolerance, we randomized 23 patients with congestive heart failure resulting from coronary artery disease to an isosorbide dinitrate or a molsidomine infusion. The drugs were titrated to decrease pulmonary capillary wedge pressure by > or = 30% or > or = 10 mm Hg. Then is...

journal_title：American heart journal

authors： Unger P,Vachiery JL,de Cannière D,Staroukine M,Berkenboom G

更新日期：1994-09-01 00:00:00

abstract：:Stress has been identified as contributing to the development of cardiovascular disease. The pathophysiologic link between stress and disease still remains unclear. Because experimental stress testing in the laboratory permits the examination of the underlying mechanism for stress-induced blood pressure, analyses of c...

journal_title：American heart journal

authors： Rüddel H,Langewitz W,Schächinger H,Schmieder R,Schulte W

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Ideal cardiovascular health (ICH) aims at primordial prevention of cardiovascular diseases in the population. However, there is a lack of research describing ICH in youth from middle-income countries. The aims of this study were to describe the prevalence of ICH at 18 and 22-years old and to investigate the ...

journal_title：American heart journal

authors： Oliveira RS,Schneider BC,Callo-Quinte G,Oliveira IO,Gonçalves H,Wehrmeister F,Menezes AMB

更新日期：2021-01-25 00:00:00

abstract：:The hemodynamic effects of intravenous and intracoronary prostacyclin (PGI2) were evaluated in anesthetized, open-chest instrumented dogs. Coronary artery and aortic blood flows, aortic and left ventricular (LV) diastolic pressure, and heart rate were measured continuously. With intravenous PGI2 both left anterior des...

journal_title：American heart journal

authors： Mehta J,Nichols WW,Mehta P,Pepine C,Conti CR

更新日期：1981-11-01 00:00:00

abstract：:In over 30 years of surveillance of 2873 women, 574 developed initial clinical manifestations of CHD. A number of antecedent metabolic risk factors proved atherogenic, including blood lipids, glucose tolerance, uric acid, and menopause. Serum total cholesterol predicts as strongly in women as in men. The predictive po...

journal_title：American heart journal

authors： Kannel WB

更新日期：1987-08-01 00:00:00

abstract：:A retrospective analysis of our experience with intraprocedural thrombus complicating percutaneous transluminal coronary angioplasty (PTCA) was undertaken. Of 983 PTCA procedures reviewed, 62 (6.3%) were complicated by thrombus. Patients were managed conservatively (group I, n = 18), with redilation (group II, n = 17)...

journal_title：American heart journal

authors： Vaitkus PT,Herrmann HC,Laskey WK

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The prodrug clopidogrel requires activation by cytochrome P-450 (CYP) enzymes for its antiplatelet effect. The genes encoding enzymes for clopidogrel activation are polymorphic, leading to reduced or increased function, depending on the respective genotype. Reduced-function alleles have been associated with ...

journal_title：American heart journal

authors： Tiroch KA,Sibbing D,Koch W,Roosen-Runge T,Mehilli J,Schömig A,Kastrati A

更新日期：2010-09-01 00:00:00

abstract：:Detection of mild hypertension by a small number of casual blood pressures may be inaccurate for the determination of average blood pressure. Nonetheless, casual pressures remain the basis for the diagnosis and treatment of hypertensive patients. We compared casual and noninvasive ambulatory blood pressure monitoring ...

journal_title：American heart journal

authors： Krakoff LR,Eison H,Phillips RH,Leiman SJ,Lev S

更新日期：1988-10-01 00:00:00

abstract：:There has been considerable debate regarding the value of programmed electrical stimulation in patients who present with asymptomatic, or minimally symptomatic, nonsustained VT. Unfortunately, there has never been a sufficiently large study of an untreated group of patients to make any sense of the issue. We culled th...

journal_title：American heart journal

authors： Kowey PR,Taylor JE,Marinchak RA,Rials SJ

更新日期：1992-02-01 00:00:00

abstract：:The response of the right ventricle to exercise was examined in 19 patients with heart disease by constructing right ventricular function curves and determining the relationship between right ventricular afterload and preload. Simultaneous cardiac output and right heart pressures were measured at rest, during exercise...

journal_title：American heart journal

authors： Weiner BH,Alpert JS,Dalen JE,Ockene IS

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND:Most analyses of complications after percutaneous coronary intervention have been limited to angiographic predictors of abrupt closure. We sought to determine the relation between baseline clinical and angiographic characteristics and clinical ischemic events and whether treatment with the platelet glycoprot...

journal_title：American heart journal

authors： Thel MC,Califf RM,Tcheng JE,Sigmon KN,Lincoff AM,Topol EJ,Ellis SG

更新日期：1999-02-01 00:00:00

abstract：:Estimating left ventricular wall stress has recognized applications, but formulae for global stress cannot be applied to ischemic ventricles. A mathematic method for estimating regional stress in infarcted ventricles has been described. The hypothesis tested was that exercise-induced ischemia increases end-systolic wa...

journal_title：American heart journal

authors： Ginzton LE,Rodrigues D,Shapiro SM,Laks MM,Conant R,Lobodzinski SM

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Pulmonary vein antrum isolation (PVI) as a treatment of paroxysmal atrial fibrillation (AF) is associated with a high rate of success; however, outcomes for treating persistent and long-standing persistent AF with PVI alone are substantially lower and often require multiple procedures to maintain long-term f...

journal_title：American heart journal

authors： Lee RJ,Lakkireddy D,Mittal S,Ellis C,Connor JT,Saville BR,Wilber D

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Glycoprotein (GP) IIb/IIIa inhibitors can improve outcomes in patients with non-ST-segment elevation acute coronary syndromes but raise the risk of bleeding, particularly if dosed in excess. The impact of GP IIb/IIIa dosing feedback on safety and major bleeding is unknown. METHODS:Glycoprotein IIb/IIIa dosi...

journal_title：American heart journal

authors： Mudrick DW,Chen AY,Roe MT,Newby LK,Gibler WB,Ohman EM,Peterson ED,Alexander KP

更新日期：2010-12-01 00:00:00