Acute electrocardiographic effects of captopril in the initial treatment of malignant or severe hypertension.

Abstract:

:We evaluated electrocardiographically the acute effect of captopril in the initial treatment of malignant or severe hypertension and the findings were compared with the data obtained with diazoxide. The captopril group included seven patients treated with captopril or with a combination of diuretics. The diazoxide group included seven patients initially treated with diazoxide. A significant and similar degree of reduction in blood pressure was observed the second day after treatment in both groups. From 15 to 60 minutes after treatment, however, the reduction in mean blood pressure was more pronounced in the diazoxide group and was followed by a reflex tachycardia. In the diazoxide group, two patients went into shock and another three had nausea and vomiting, whereas in the captopril group there were no complications in any of the patients. In the captopril group ECG ST-T findings in leads V5 and V6 did not deteriorate, while in the diazoxide group there was a significant deterioration (p = 0.01). Thus captopril may be an effective and safe compound for the initial treatment of malignant or severe hypertension.

journal_name

Am Heart J

journal_title

American heart journal

authors

Abe I,Kawasaki T,Kawazoe N,Omae T

doi

10.1016/0002-8703(83)90702-0

subject

Has Abstract

pub_date

1983-09-01 00:00:00

pages

558-62

issue

3

eissn

0002-8703

issn

1097-6744

pii

0002-8703(83)90702-0

journal_volume

106

pub_type

杂志文章
  • Adherence to practice guidelines: the role of specialty society guidelines.

    abstract:BACKGROUND:Physician adherence to guidelines is often poor, but the reasons have not been completely studied. We investigated whether physician adherence to guidelines for percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass grafting (CABG) varied by source, development methods, or the exten...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2003.35

    authors: Leape LL,Weissman JS,Schneider EC,Piana RN,Gatsonis C,Epstein AM

    更新日期:2003-01-01 00:00:00

  • Safety assessment of perflenapent emulsion for echocardiographic contrast enhancement in patients with congestive heart failure or chronic obstructive pulmonary disease.

    abstract:BACKGROUND:Perflenapent injectable emulsion is a newer echocardiographic contrast agent that provides chamber opacification and improved endocardial border delineation. In >1000 patients tested, adverse effects have been minimal. However, previous studies have included few patients with congestive heart failure (CHF) o...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1067/mhj.2000.106612

    authors: Kitzman DW,Wesley DJ

    更新日期:2000-06-01 00:00:00

  • Efficacy and safety of dual antiplatelet therapy after coronary stenting in patients with chronic kidney disease.

    abstract:BACKGROUND:We compared efficacy and safety of short- (3 or 6 months) versus long-term (≥12 months) dual antiplatelet therapy (DAPT) after drug-eluting stent (DES) implantation, according to the presence of chronic kidney disease (CKD). METHODS:Patient-level pooled analysis was performed with 7242 patients (87.2% with ...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2017.11.013

    authors: Hwang D,Park KW,Lee JM,Rhee TM,Hong MK,Jang Y,Valgimigli M,Colombo A,Gilard M,Palmerini T,Stone GW,Kim HS

    更新日期:2018-03-01 00:00:00

  • Spaced administration of PA32540 and clopidogrel results in greater platelet inhibition than synchronous administration of enteric-coated aspirin and enteric-coated omeprazole and clopidogrel.

    abstract:BACKGROUND:A common regimen for patients requiring dual-antiplatelet therapy who are at risk for gastrointestinal complications is the synchronous administration of enteric-coated (EC) aspirin, a proton pump inhibitor, and clopidogrel, although proton pump inhibitors have the potential for pharmacodynamic interaction w...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2012.07.032

    authors: Gurbel PA,Bliden KP,Fort JG,Jeong YH,Shuldiner A,Chai S,Gesheff T,Antonino M,Gesheff M,Zhang Y,Tantry US

    更新日期:2013-02-01 00:00:00

  • Association between bleeding, blood transfusion, and costs among patients with non-ST-segment elevation acute coronary syndromes.

    abstract:BACKGROUND:Bleeding and blood transfusion are associated with increased morbidity and mortality among patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS); however, the economic consequences of these complications are not well defined. We sought to determine the relationship between bleeding, bloo...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2007.10.014

    authors: Rao SV,Kaul PR,Liao L,Armstrong PW,Ohman EM,Granger CB,Califf RM,Harrington RA,Eisenstein EL,Mark DB

    更新日期:2008-02-01 00:00:00

  • Brachytherapy and bivalirudin evaluation study.

    abstract:BACKGROUND:Bivalirudin is shown to be a competent substitute for heparin in percutaneous coronary intervention (PCI). The safety and efficacy of bivalirudin in patients undergoing PCI and vascular brachytherapy (VBT) are not known. This study aimed to assess the safety and efficacy of bivalirudin as a single antithromb...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2004.11.013

    authors: Kuchulakanti P,Wolfram R,Torguson R,Rha SW,Cheneau E,Pinnow EE,Canos D,Satler LF,Pichard AD,Kent KM,Waksman R

    更新日期:2005-10-01 00:00:00

  • The association between body mass index and coronary artery disease severity: a comparison of black and white patients.

    abstract:INTRODUCTION:Despite known associations between obesity and cardiovascular disease, the relationship between obesity as reflected by body mass index (BMI) and angiographic coronary artery disease (CAD) is not fully understood. Moreover, this relationship has not been adequately defined in black patients, a group demons...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2013.12.009

    authors: Stalls CM,Triplette MA,Viera AJ,Pathman DE,Cohen MG,Rossi JS

    更新日期:2014-04-01 00:00:00

  • The association between socioeconomic status of high-risk patients with coronary heart disease and the treatment rates of evidence-based medicine for coronary heart disease secondary prevention in China: Results from the Bridging the Gap on CHD Secondary

    abstract:BACKGROUND:In China, low socioeconomic status (SES) may be a barrier for patients with coronary heart disease (CHD) to receive adequate treatment because of their inadequate access to health resources. This study aims to evaluate whether and to what extent SES is associated with the treatment of CHD patients. METHODS:...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2008.12.009

    authors: Niu S,Zhao D,Zhu J,Liu J,Liu Q,Liu J,Wang W,Smith SC Jr,BRIG project.

    更新日期:2009-04-01 00:00:00

  • Hemodynamic effects of molsidomine in patients with acute myocardial infarction.

    abstract::The hemodynamic effects of molsidomine were studied in 48 patients with acute myocardial infarction and compared with hemodynamic properties in a control group of 24 patients. The most pronounced decrease in pulmonary artery diastolic pressure occurs between 30 and 60 minutes after oral administration of 8 to 12 mg (n...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-8703(85)90688-x

    authors: Reifart N,Neidl K,Kaltenbach M,Bussmann WD

    更新日期:1985-03-01 00:00:00

  • Randomized evaluation of short-term dual antiplatelet therapy in patients with acute coronary syndrome treated with the COMBO dual therapy stent: rationale and design of the REDUCE trial.

    abstract:BACKGROUND:The optimal duration of dual antiplatelet therapy (DAPT) in acute coronary syndrome (ACS) patients treated with drug eluting stents (DES) is still under debate. Recent meta-analyses on ≤6months versus 12months DAPT suggest that bleeding rates can be reduced, without a higher rate of thrombotic complications....

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2016.04.016

    authors: Camaro C,Damen SA,Brouwer MA,Kedhi E,Lee SW,Verdoia M,Barbieri L,Rognoni A,van T Hof AW,Ligtenberg E,de Boer MJ,Suryapranata H,De Luca G

    更新日期:2016-08-01 00:00:00

  • Normal intima-media thickness on carotid ultrasound reliably excludes an ischemic cause of cardiomyopathy.

    abstract:BACKGROUND:Coronary artery disease (CAD) is the most common cause of left ventricular systolic dysfunction (LVSD). Patients with ischemia as the cause of LVSD may warrant revascularization. Angiography is the most accurate method of CAD diagnosis but is invasive, expensive, and associated with some risk. Noninvasive im...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.ahj.2010.03.026

    authors: Reynolds HR,Steckman DA,Tunick PA,Kronzon I,Lobach I,Rosenzweig BP

    更新日期:2010-06-01 00:00:00

  • Effect of age on mortality in coronary artery bypass surgery in New York, 1991-1992.

    abstract::The purpose of this study was to determine the effect of age on the in-hospital mortality of all 30,972 patients undergoing coronary artery bypass graft (CABG) surgery in New York in 1991 and 1992. Mortality rates were relatively low for patients 40-49, 50-59, and 60-64, 65-69, and 70-74 years old (1.10%, 1.65%, 2.17%...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(94)90750-1

    authors: Hannan EL,Burke J

    更新日期:1994-12-01 00:00:00

  • Three-dimensional echocardiographic evaluation of left ventricular volume: comparison of Doppler myocardial imaging and standard gray-scale imaging with cineventriculography--an in vitro and in vivo study.

    abstract:BACKGROUND:Standard gray-scale imaging (GSI), three-dimensional (3D) echocardiography has been shown to be superior to two-dimensional echocardiography in measuring left ventricular volume. However, the often relatively poor quality of transthoracic gray-scale data can limit the potential application of this technique....

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(98)70061-4

    authors: Lange A,Palka P,Nowicki A,Olszewski R,Anderson T,Adamus J,Sutherland GR,Fox KA

    更新日期:1998-06-01 00:00:00

  • Survival of DDD pacing mode after atrioventricular junction ablation and pacing for refractory atrial fibrillation.

    abstract:BACKGROUND:Patients with recurrent forms of atrial fibrillation may receive dual-chamber pacemakers after atrioventricular junction ablation for refractory symptoms. These patients are at risk for chronic atrial fibrillation, which would negate the benefits of dual-chamber pacing. The purpose of this study was to exami...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s0002-8703(99)70223-1

    authors: Wood MA,Curtis AB,Takle-Newhouse TA,Ellenbogen KA

    更新日期:1999-04-01 00:00:00

  • Validation of pressure-volume data obtained in patients by initial transit radionuclide angiocardiography.

    abstract::In order to validate the measurement of pressure-volume loops and stroke work in humans, simultaneous digital subtraction ventriculography (DSA) and first-pass radionuclide angiocardiography (RNA) coupled with high-fidelity micromanometer left ventricular pressure measurements were undertaken in 34 patients, mean age ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(89)90234-2

    authors: Harpole DH,Skelton TN,Davidson CJ,Jones RH,Bashore TM

    更新日期:1989-11-01 00:00:00

  • Borderline left ventricles in prenatally diagnosed atrioventricular septal defect or double outlet right ventricle: echocardiographic predictors of biventricular repair.

    abstract:BACKGROUND:Atrioventricular septal defect (AVSD) and double outlet right ventricle (DORV) with normally related great arteries and normal ventricular sizes are associated with a good long-term prognosis after biventricular (BV) repair. The outcome of cases with a borderline small left ventricle (bLV) is unclear. The pu...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2006.04.018

    authors: Pitkänen OM,Hornberger LK,Miner SE,Mondal T,Smallhorn JF,Jaeggi E,Nield LE

    更新日期:2006-07-01 00:00:00

  • Association between toll-like receptor 8 expression and adverse clinical outcomes in patients with enterovirus-associated dilated cardiomyopathy.

    abstract:BACKGROUND:In recent reports, human toll-like receptor (TLR) 8 mediates the antiviral response by recognizing single-stranded RNA. The inflammatory response against enteroviral (EV) RNA replication may play an important role in dilated cardiomyopathy (DCM). The purpose of this study was to determine whether TLR8 was ex...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2007.05.010

    authors: Satoh M,Akatsu T,Ishikawa Y,Minami Y,Takahashi Y,Nakamura M

    更新日期:2007-09-01 00:00:00

  • Angiotensin inhibition in renovascular disease: a population-based cohort study.

    abstract:BACKGROUND:Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers effectively reduce blood pressure in patients with renovascular disease (RVD); yet, randomized cardiovascular prevention trials of these drugs typically exclude individuals with this condition. PATIENTS AND METHODS:We studied the ass...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2008.05.013

    authors: Hackam DG,Duong-Hua ML,Mamdani M,Li P,Tobe SW,Spence JD,Garg AX

    更新日期:2008-09-01 00:00:00

  • Pre-excitation of the ventricle associated with total intra His bundle block.

    abstract::A case with total intra-His bundle block and intermittent pre-excitation syndrome is presented. During A-V conduction there was a P-delta interval of 130 msec. with a P-A interval of 20 msec., an A-H interval of 60 msec. and an H-V interval of 50 msec. During rapid atrial pacing the P-delta interval increased primaril...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(77)80350-5

    authors: Probst P,Pachinger O,Steinbach K,Kaindl F

    更新日期:1977-07-01 00:00:00

  • Echocardiographic characterization of left ventricular adaptation in a genetically determined heart failure rat model.

    abstract::This study uses echocardiography to characterize the pattern of left ventricular hypertrophy in a new hypertensive heart failure-prone rat strain designated SHHF/Mcc-cp (SHHF). M-mode echocardiograms of the left ventricle in nine 10- to 12-month old SHHF rats and nine age-matched spontaneously hypertensive rats (SHR) ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(95)90081-0

    authors: Haas GJ,McCune SA,Brown DM,Cody RJ

    更新日期:1995-10-01 00:00:00

  • Plasma levels of immunoreactive atrial natriuretic factor increase during supraventricular tachycardia.

    abstract::A significant diuretic and natriuretic response occurs during paroxysmal supraventricular tachycardia (SVT). Although the diuresis may be secondary to suppression of vasopressin secretion, the etiology of the natriuresis remains unexplained. To determine if atrial natriuretic factor (ANF) could contribute to the polyu...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(86)90301-7

    authors: Nicklas JM,DiCarlo LA,Koller PT,Morady F,Diltz EA,Shenker Y,Grekin RJ

    更新日期:1986-11-01 00:00:00

  • Comparison of the dose-response relationships of 2 lipid-lowering agents: a Bayesian meta-analysis.

    abstract:BACKGROUND:Comparing the dose-response of a new drug to that of a previously studied drug can aid in understanding their relative potencies. Two dose-finding studies addressed the effect of a new drug, rosuvastatin, on its ability to decrease low-density lipoprotein cholesterol (LDL-C) levels. One of these studies incl...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/S0002-8703(03)00106-6

    authors: Berry DA,Berry SM,McKellar J,Pearson TA

    更新日期:2003-06-01 00:00:00

  • Prolongation of refractoriness and activation time in normal canine ventricular myocardium following bolus administration of lidocaine.

    abstract::This study examines the electrophysiologic effects of an intravenous bolus of lidocaine in the normal canine ventricle. In 14 open-chest dogs, left ventricular effective refractory period, ventricular repolarization time, and activation time were measured continuously during ventricular pacing (150/min) before, during...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(85)90559-9

    authors: Martins JB,Kelly KJ

    更新日期:1985-03-01 00:00:00

  • Clinical outcomes after percutaneous revascularization versus medical management in patients with significant renal artery stenosis: a meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:We sought to systematically evaluate whether percutaneous revascularization is associated with additional clinical benefit in patients with renal artery stenosis (RAS) as compared with medical management alone. METHODS:We included randomized controlled trials that compared percutaneous revascularization in ...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.ahj.2010.12.006

    authors: Kumbhani DJ,Bavry AA,Harvey JE,de Souza R,Scarpioni R,Bhatt DL,Kapadia SR

    更新日期:2011-03-01 00:00:00

  • Ebstein's anomaly of the tricuspid valve and prolapse of the mitral valve.

    abstract::The hearts from 10 necropsy patients with Ebstein's anomaly of the tricuspid valve were examined for abnormalities of the mitral valve. Five patients were under 1 year of age and none had an abnormal mitral valve. The other five patients were ages 18 to 72 years (mean 36 years); all had focal fibrous thickening of the...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(81)90663-3

    authors: Cabin HS,Roberts WC

    更新日期:1981-02-01 00:00:00

  • Percutaneous coronary implantation of sirolimus-eluting stents in unselected patients and lesions: clinical results and multiple outcome predictors.

    abstract:BACKGROUND:Sirolimus-eluting stents (SES) prevent restenosis and repeat percutaneous coronary intervention (PCI), but safety data in unselected patients are limited, especially for intermediate-term follow-up. METHODS:All patients undergoing SES implantation at 4 Italian centers were enrolled into a dedicated database...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2008.06.030

    authors: Sangiorgi G,Romagnoli E,Biondi-Zoccai G,Margheri M,Tamburino C,Barbagallo R,Falchetti E,Vittori G,Agostoni P,Cosgrave J,Colombo A,RECIPE (Real-world Eluting-stent Comparative Italian retrosPective Evaluation) Study Investigators.

    更新日期:2008-11-01 00:00:00

  • Morbidity and mortality rates in elderly patients undergoing percutaneous coronary transluminal angioplasty.

    abstract::Although successful dilatation of a target lesion by means of percutaneous transluminal coronary angioplasty (PTCA) can be attained as frequently in elderly as in younger patients, elderly patients have a higher risk of complications. Furthermore, cohorts of patients older than 75 years and undergoing PTCA include mor...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(94)90267-4

    authors: Lindsay J Jr,Reddy VM,Pinnow EE,Little T,Pichard AD

    更新日期:1994-10-01 00:00:00

  • Programmed left ventricular contrast injection. A method to minimize left ventricular irritability during angiography.

    abstract::Left ventricular angiography frequently produces one or more premature atrial or ventricular contractions which may make quantitative volume analysis unreliable. Three hundred left ventricular power injections were analyzed and found to produce premature ventricular contractions (PVC's) in 28 per cent of injections an...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(77)80305-0

    authors: Caldwell JH,Kennedy JW

    更新日期:1977-02-01 00:00:00

  • Short-term infarct vessel patency with aspirin and dipyridamole started 24 to 36 hours after intravenous streptokinase.

    abstract::The duration of intravenous heparin therapy required to maintain patency of the infarct-related artery after intravenous streptokinase is uncertain. Twenty-eight patients were prospectively treated with 1.5 million units of intravenous streptokinase within 4 hours of onset of chest pain. Intravenous heparin was begun ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(88)90870-8

    authors: Hays LJ,Beller GA,Moore CA,Burwell LR,Craddock GB,Gascho JA,Smucker ML,Tedesco C,Nygaard TW

    更新日期:1988-04-01 00:00:00

  • Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance: rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial.

    abstract::Patients with impaired glucose tolerance (IGT) have increased risk for developing type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Lifestyle modification and medication can prevent or delay progression to diabetes (PD), but whether such interventions also reduce the risk of CVD has not been rigorously...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2008.05.017

    authors: Califf RM,Boolell M,Haffner SM,Bethel M,McMurray J,Duggal A,Holman RR,NAVIGATOR Study Group.

    更新日期:2008-10-01 00:00:00