Association between toll-like receptor 8 expression and adverse clinical outcomes in patients with enterovirus-associated dilated cardiomyopathy.

abstract：BACKGROUND:Today most patients with congenital heart disease survive childhood to be cared for by adult cardiologists. The number of physicians that should be trained to manage these lesions is unknown because we do not know the number of patients. METHODS:To answer this question, the expected numbers of infants with ...

journal_title：American heart journal

authors： Hoffman JI,Kaplan S,Liberthson RR

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Although quantification of the impact of treatment on survival remains the cornerstone of clinical research, the assessment of a broader range of disease outcomes is growing increasingly important. This manuscript provides an overview of the considerations made regarding quantification of a range of clinical...

journal_title：American heart journal

authors： Spertus JA,Tooley J,Jones P,Poston C,Mahoney E,Deedwania P,Hurley S,Pitt B,Weintraub WS

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) in the setting of heart failure (HF) is linked to embolic stroke and exacerbation of HF. The rate of new-onset AF in patients with left ventricular dysfunction and mild to moderate HF enrolled in the SoLVD trials was significantly lower with enalapril than with placebo (5.4% vs 24% o...

journal_title：American heart journal

authors： Wagner M,Rindress D,Desjardins B,Meilleur MC,Ducharme A,Tardif JC

更新日期：2005-11-01 00:00:00

abstract：:We investigated the incidence and mechanism of pulmonary artery hypertension (PAH) in a consecutive series of patients with aortic stenosis who were undergoing diagnostic cardiac catheterization. Forty-five patients with severe aortic stenosis were divided into two groups: group 1 comprised 13 patients (29%) with PAH ...

journal_title：American heart journal

authors： Silver K,Aurigemma G,Krendel S,Barry N,Ockene I,Alpert J

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Chronotropic incompetence and left ventricular (LV) dilatation have both been shown to be markers of an adverse cardiovascular prognosis. Chronotropic incompetence has been described in patients with symptomatic LV dilatation and dysfunction, but the effect of asymptomatic LV dilatation and hypertrophy on ex...

journal_title：American heart journal

authors： Lauer MS,Larson MG,Evans JC,Levy D

更新日期：1999-05-01 00:00:00

abstract：:T-lymphocyte levels may adversely affect the clinical course and outcome of patients with acute myocardial infarction (AMI). To characterize the T-lymphocyte profile during AMI and to explore whether these cells play a detrimental role in the extent of myocardial insult, levels of T-lymphocyte subpopulations, free sol...

journal_title：American heart journal

authors： Blum A,Sclarovsky S,Rehavia E,Shohat B

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Appropriate thromboprophylaxis for patients with atrial fibrillation or atrial flutter (AF) remains a national challenge. METHODS:We hypothesized that a shared decision-making interaction facilitated by an Atrial Fibrillation Shared Decision Making Tool (AFSDM) would improve patient knowledge about atrial f...

journal_title：American heart journal

authors： Eckman MH,Costea A,Attari M,Munjal J,Wise RE,Knochelmann C,Flaherty ML,Baker P,Ireton R,Harnett BM,Leonard AC,Steen D,Rose A,Kues J

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Coronary heart disease continues to be one of the most common chronic illnesses in the United States and most of the developed world. Clinicians and health authorities have interest in identifying individuals at increased risk of CHD. The Framingham Heart Study has over the years produced mathematical "healt...

journal_title：American heart journal

authors： D'Agostino RB,Russell MW,Huse DM,Ellison RC,Silbershatz H,Wilson PW,Hartz SC

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:The acute benefits of platelet glycoprotein IIb/IIIa inhibitors for non-ST-segment elevation acute coronary syndromes (NSTE ACS) remain unclear. METHODS:In this pilot trial, 311 patients with NSTE ACS were randomly assigned in the emergency department to double-blinded therapy with eptifibatide or placebo f...

journal_title：American heart journal

authors： Roe MT,Christenson RH,Ohman EM,Bahr R,Fesmire FM,Storrow A,Mollod M,Peacock WF,Rosenblatt JA,Yang H,Fraulo ES,Hoekstra JW,Gibler WB,EARLY Investigators.,Emergency Medicine Cardiac Research and Education Group.

更新日期：2003-12-01 00:00:00

abstract：:Symptoms of myocardial ischemia, such as chest pain (sometimes with anginal features), acute myocardial infarction, and segmental wall motion abnormalities (including left ventricular apical aneurysm), frequently occur in patients with Chagas' heart disease. Because these clinical findings occur in the presence of nor...

journal_title：American heart journal

authors： Torres FW,Acquatella H,Condado JA,Dinsmore R,Palacios IF

更新日期：1995-05-01 00:00:00

abstract：:Following pulmonary infarction, three patients developed the classical signs and symptoms of the Dressler syndrome associated with persistent left pleural effusion. Each responded dramatically to corticosteroid therapy. While the pathogenesis of this "Post-Pulmonary Infarction syndrome," like the Dressler syndrome, is...

journal_title：American heart journal

authors： Sklaroff HJ

更新日期：1979-12-01 00:00:00

abstract：:The QRS complex and ST segment in the ECGs of 80 patients who died of an acute myocardial infarction (MI) were studied in relation to the extent of the MI (subendocardial vs. transmural). Changes in the QRS complex developed in nine out of the 15 cases with an acute subendocardial MI. Five of these cases fulfilled the...

journal_title：American heart journal

authors： Raunio H,Rissanen V,Romppanen T,Jokinen Y,Rehnberg S,Helin M,Pyörälä K

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:The speed of reperfusion (door-to-balloon [D2B] time) is a well established performance metric for patients with ST-elevation myocardial infarction. Although preferably D2B times should be

journal_title：American heart journal

authors： Mehta RH,Bufalino VJ,Pan W,Hernandez AF,Cannon CP,Fonarow GC,Peterson ED,American Heart Association Get With the Guidelines Investigators.

更新日期：2008-06-01 00:00:00

abstract：:Estimating left ventricular wall stress has recognized applications, but formulae for global stress cannot be applied to ischemic ventricles. A mathematic method for estimating regional stress in infarcted ventricles has been described. The hypothesis tested was that exercise-induced ischemia increases end-systolic wa...

journal_title：American heart journal

authors： Ginzton LE,Rodrigues D,Shapiro SM,Laks MM,Conant R,Lobodzinski SM

更新日期：1996-10-01 00:00:00

abstract：:While the total ischemic burden on the left ventricle represents the combined effects of both symptomatic and asymptomatic myocardial ischemia, the total vascular burden has many components including an increased systemic peripheral vascular resistance, an increased pulmonary vascular resistance, and an increased coro...

journal_title：American heart journal

authors： Opie LH,Commerford PJ

更新日期：1988-01-01 00:00:00

abstract：:Doxorubicin (Adriamycin) is an effective anticancer agent but its therapeutic value is limited by its myocardial cardiotoxicity. To improve early detection of doxorubicin cardiotoxicity, studies were performed in patients with long-term doxorubicin treatment using pulsed Doppler echocardiography to assess the changes ...

journal_title：American heart journal

authors： Marchandise B,Schroeder E,Bosly A,Doyen C,Weynants P,Kremer R,Pouleur H

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Many young investigators are interested in cardiovascular (CV) outcomes research; however, the current training experience of early investigators across the United States is uncertain. METHODS:From April to November 2014, we surveyed mentees and mentors of early-stage CV outcomes investigators across the Un...

journal_title：American heart journal

authors： Khazanie P,Al-Khatib SM,Wang TY,Crowley MJ,Kressin NR,Krumholz HM,Kiefe CI,Wells BL,O'Brien SM,Peterson ED,Sanders GD

更新日期：2018-02-01 00:00:00

abstract：:This case report presents a young adult with asymmetric septal hypertrophy (ASH) and syncope. Infranodal complete heart block was demonstrated as his cause for syncope. Therapy consisted of implantation of a A-V sequential pacemaker. Cardiac output determinations and systolic time intervals demonstrated the beneficial...

journal_title：American heart journal

authors： Chmielewski CA,Riley RS,Mahendran A,Most AS

更新日期：1977-01-01 00:00:00

abstract：UNLABELLED:Antiarrhythmic agents enhance maintenance of sinus rhythm (SR) after direct current cardioversion (DCC) for atrial fibrillation but there are few comparative trials. BACKGROUND:The aims of the study were (1) to establish whether patients successfully cardioverted to SR are more likely to stay in SR over 6 m...

journal_title：American heart journal

authors： Vijayalakshmi K,Whittaker VJ,Sutton A,Campbell P,Wright RA,Hall JA,Harcombe AA,Linker NJ,Stewart MJ,Davies A,de Belder MA

更新日期：2006-04-01 00:00:00

abstract：:The present study refers to six patients in whom an A-V reciprocal rhythm could be documented; in four cases it took the form of sustained tachycardia. None of the patients showed any ECG feature of ventricular pre-excitation (PR interval of more than 0.12 sec. and normal QRS configuration). The extrastimulus method s...

journal_title：American heart journal

authors： Touboul P,Huerta F,Porte J,Delahaye JP

更新日期：1976-01-01 00:00:00

abstract：:We studied 16 patients with chronic aortic insufficiency to compare a method for measuring regurgitant volume with color Doppler flow mapping to stroke count ratio determined by radionuclide ventriculography and to ventricular volumes assessed by two-dimensional echocardiography. A real-time color flow map of the left...

journal_title：American heart journal

authors： Bouchard A,Yock P,Schiller NB,Blumlein S,Botvinick EH,Greenberg B,Cheitlin M,Massie BM

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Cohort studies have suggested little effect of coffee consumption on risk of acute myocardial infarction. The effect of coffee consumption on prognosis after myocardial infarction is uncertain. METHODS:In a population-based inception cohort study, we followed 1,369 patients hospitalized with a confirmed fir...

journal_title：American heart journal

authors： Mukamal KJ,Hallqvist J,Hammar N,Ljung R,Gémes K,Ahlbom A,Ahnve S,Janszky I

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Kidney failure causes anemia and is associated with a very high risk of coronary heart disease (CHD). Mildly to moderately decreased kidney function is far more common and also is associated with an elevated prevalence of anemia and CHD risk. Recent data suggest an even higher risk of CHD when both condition...

journal_title：American heart journal

authors： Astor BC,Coresh J,Heiss G,Pettitt D,Sarnak MJ

更新日期：2006-02-01 00:00:00

abstract：:We compared the pauses that followed the spontaneous termination of supraventricular tachyarrhythmias with the pauses that followed the cessation of atrial overdrive pacing in 21 patients. In 10 patients with abnormal sinus node function and in 11 patients with normal sinus node function we recorded the spontaneous te...

journal_title：American heart journal

authors： Gang ES,Reiffel JA,Livelli FD Jr,Bigger JT Jr

更新日期：1983-02-01 00:00:00

abstract：:The MAPHY Study was conducted to investigate whether metoprolol, a relatively beta 1-selective beta-blocker, given as initial antihypertensive treatment, would lower cardiovascular complications of high blood pressure to a greater extent than do thiazide diuretics as initial treatment at similar blood pressure control...

journal_title：American heart journal

authors： Wikstrand J

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Arterial compliance is related to left ventricular hypertrophy and risk for cardiovascular disease events; however, its association with coronary artery stenosis remains uncertain. We sought to assess the relation between lower extremity arterial compliance and presence of angiographically defined coronary a...

journal_title：American heart journal

authors： Herrington DM,Kesler K,Reiber Jh,Davis W,Brown WV,Helms R,Mallon SM,Raines J

更新日期：2003-10-01 00:00:00

abstract：:Coronary heart disease is the single largest cause of morbidity and mortality in the United States. The link between elevated low-density lipoprotein cholesterol (LDL-C) levels and coronary heart disease (CHD) has been clearly established. However, triglycerides (TG) are increasingly believed to be independently assoc...

journal_title：American heart journal

authors： Szapary PO,Rader DJ

更新日期：2004-08-01 00:00:00

abstract：:The relation of alcohol consumption to coronary heart disease (CHD) was examined in a cohort of 1910 employed men aged 38 to 55 years enrolled in the Albany Study, a prospective investigation of factors related to cardiovascular disease. Two follow-up periods were examined, one between 1953-54 and 1971-72, the other a...

journal_title：American heart journal

authors： Gordon T,Doyle JT

更新日期：1985-08-01 00:00:00

abstract：:An angioplasty catheter was developed to allow measurement of absolute coronary blood flow during interventional procedures. This method uses electrical impedance changes induced by a 0.5 ml bolus of 5% dextrose solution and indicator-dilution principles. The indicator is injected through a port located just proximal ...

journal_title：American heart journal

authors： Martin LW,Johnson RA,Scott H,Robinson S,Beauman G,Englehardt M,Vogel RA

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:The ODYSSEY COMBO I study (http://clinicaltrials.gov/show/NCT01644175) evaluated efficacy and safety of alirocumab as add-on therapy to stable maximally tolerated daily statin with or without other lipid-lowering therapy in high cardiovascular risk patients with suboptimally controlled hypercholesterolemia. ...

journal_title：American heart journal

authors： Kereiakes DJ,Robinson JG,Cannon CP,Lorenzato C,Pordy R,Chaudhari U,Colhoun HM

更新日期：2015-06-01 00:00:00