Impedance measurement of absolute blood flow using an angioplasty catheter: a validation study.

Abstract:

:An angioplasty catheter was developed to allow measurement of absolute coronary blood flow during interventional procedures. This method uses electrical impedance changes induced by a 0.5 ml bolus of 5% dextrose solution and indicator-dilution principles. The indicator is injected through a port located just proximal to the dilating balloon and the resulting changes in blood impedance are measured by electrodes at the catheter tip. Excellent linear correlations were found between known flow in 2 to 4 mm to diameter plastic tubes and catheter measurements (r = 0.99) and between timed collection canine femoral artery flow and catheter measurements (r = 0.97). Final validation was performed in canine coronary arteries using electromagnetic flowmeter data as the standard (r = 0.94). Thus accurate clinical determination of absolute coronary blood flow can be accomplished using this relatively inexpensive and simple catheter technique.

journal_name

Am Heart J

journal_title

American heart journal

authors

Martin LW,Johnson RA,Scott H,Robinson S,Beauman G,Englehardt M,Vogel RA

doi

10.1016/0002-8703(91)90184-j

subject

Has Abstract

pub_date

1991-03-01 00:00:00

pages

745-52

issue

3 Pt 1

eissn

0002-8703

issn

1097-6744

pii

0002-8703(91)90184-J

journal_volume

121

pub_type

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