Noninvasive quantification of mitral regurgitation in dilated cardiomyopathy: correlation of two Doppler echocardiographic methods.

Abstract:

:The presence and severity of functional mitral regurgitation were quantified by Doppler echocardiography in 17 patients with dilated cardiomyopathy and no evidence of primary valvular disease. Mitral regurgitant fraction was greater than 20% in 11 of the 17 patients, and exceeded 40% in four patients. Total stroke volume, calculated from the difference between end-diastolic and end-systolic volumes obtained by two-dimensional echocardiography, correlated well with mitral valve inflow determined by Doppler echocardiography (r = 0.90, p less than 0.001). Similarly, mitral regurgitant volume, calculated as the difference between echocardiographic total stroke volume and forward aortic volume obtained by Doppler echocardiography, correlated well with regurgitant volume calculated as the difference between mitral valve inflow and forward aortic flow, both determined by Doppler echocardiography (r = 0.90, p less than 0.001). Accordingly, functional mitral regurgitation can be conveniently demonstrated in patients with dilated cardiomyopathy by two different Doppler echocardiography methods, whose results are closely correlated. Mitral regurgitant fraction is greater than 20% in two thirds of the patients with a dilated cardiomyopathy.

journal_name

Am Heart J

journal_title

American heart journal

authors

Keren G,Katz S,Strom J,Sonnenblick EH,LeJemtel TH

doi

10.1016/0002-8703(88)90334-1

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

758-64

issue

3

eissn

0002-8703

issn

1097-6744

pii

0002-8703(88)90334-1

journal_volume

116

pub_type

杂志文章
  • Value and limitations of Doppler ultrasound in the evaluation of aortic stenosis: a statistical analysis of 70 consecutive patients.

    abstract::Continuous-mode Doppler ultrasound and cardiac catheterization were performed within 1.4 +/- 2.0 days in 70 patients, aged 26 to 84 (mean 67 +/- 11) years, with suspected aortic stenosis. Optimal Doppler spectral display signal was recorded from the apical window in 43% of the patients, the second or third right paras...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(86)90694-0

    authors: Panidis IP,Mintz GS,Ross J

    更新日期:1986-07-01 00:00:00

  • Predictors of surgical mortality and long-term results of endocardial resection for drug-refractory ventricular tachycardia.

    abstract::The results of surgical therapy performed in 51 consecutive patients with ventricular tachycardia were reviewed to determine short- and long-term predictors of success of such therapy in preventing recurrences of life-threatening ventricular arrhythmias. Of 41 patients (80%) who survived surgery, 40 had postoperative ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(92)90404-j

    authors: Mittleman RS,Candinas R,Dahlberg S,Vander Salm T,Moran JM,Huang SK

    更新日期:1992-11-01 00:00:00

  • The role of the central nervous system in chronic congestive heart failure.

    abstract::Even though congestive heart failure is extremely common, the mechanisms responsible for the clinical manifestations remain a puzzle. The central and autonomic (sympathetic) nervous systems are responsible for a large part of the clinical manifestations. The role of the nervous system in CHF is discussed briefly. It i...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(78)90471-4

    authors: Burch GE

    更新日期:1978-02-01 00:00:00

  • Galectin-3 and incidence of atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) study.

    abstract:BACKGROUND:Galectin-3, a β-galactoside binding lectin involved in important regulatory roles in adhesion, inflammation, immunity, and fibrosis, may be relevant to atrial fibrillation (AF) etiology. METHODS:We included 8,436 participants free of AF at baseline (1996-1998) and with measures of plasma galectin-3 from the...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2017.07.001

    authors: Fashanu OE,Norby FL,Aguilar D,Ballantyne CM,Hoogeveen RC,Chen LY,Soliman EZ,Alonso A,Folsom AR

    更新日期:2017-10-01 00:00:00

  • Validation of a specific activity questionnaire to estimate exercise tolerance in patients referred for exercise testing.

    abstract:BACKGROUND:Physical activity and symptom questionnaires have been used as surrogates for exercise testing to estimate a patient's functional capacity and to individualize an exercise testing protocol in accordance with exercise testing guidelines. To validate these approaches, they must be compared with measured oxygen...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2001.118740

    authors: Myers J,Bader D,Madhavan R,Froelicher V

    更新日期:2001-12-01 00:00:00

  • The CSL112-2001 trial: Safety and tolerability of multiple doses of CSL112 (apolipoprotein A-I [human]), an intravenous formulation of plasma-derived apolipoprotein A-I, among subjects with moderate renal impairment after acute myocardial infarction.

    abstract:BACKGROUND:CSL112 (apolipoprotein A-I [human]) is a plasma-derived apolipoprotein A-I developed for early reduction of cardiovascular risk following an acute myocardial infarction (AMI). The safety of CSL112 among AMI subjects with moderate, stage 3 chronic kidney disease (CKD) is unknown. METHODS:CSL112_2001, a multi...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2018.11.008

    authors: Gibson CM,Kerneis M,Yee MK,Daaboul Y,Korjian S,Mehr AP,Tricoci P,Alexander JH,Kastelein JJP,Mehran R,Bode C,Lewis BS,Mehta R,Duffy D,Feaster J,Halabi M,Angiolillo DJ,Duerschmied D,Ophuis TO,Merkely B

    更新日期:2019-02-01 00:00:00

  • M-mode echocardiography in left bundle branch block: significance of frontal plane QRS axis.

    abstract::M-mode echocardiograms were obtained in 48 patients with complete left bundle branch block (LBBB). Of these 48 patients, 28 had LBBB with normal frontal plane QRS axis (-20 degrees to +90 degrees, mean +/- SD 18 degrees +/- 34 degrees), and 20 had LBBB with a left axis deviation (LAD) (-30 degrees to -60 degrees, mean...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(82)90010-2

    authors: Strasberg B,Rich S,Lam W,Swiryn S,Bauernfeind R,Rosen KM

    更新日期:1982-10-01 00:00:00

  • Preprocedural statin use is associated with a reduced hazard of postprocedural myonecrosis in patients undergoing rotational atherectomy--a propensity-adjusted analysis.

    abstract::Incidence of myonecrosis in patients undergoing rotational atherectomy was evaluated by preprocedural statin use. The incidence of any myonecrosis (24.1% vs 52.3%, P < .001) or significant myonecrosis (7.5% vs 21.8%, P < .001) was significantly lower among patients pretreated with statins. This difference remained sig...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2006.02.026

    authors: Gurm HS,Breitbart Y,Vivekanathan D,Yen MH,Fathi R,Ziada KM,Whitlow PL,Ellis SG

    更新日期:2006-05-01 00:00:00

  • Identification of the ischemic etiology of heart failure by cardiovascular magnetic resonance imaging: diagnostic accuracy of late gadolinium enhancement.

    abstract:BACKGROUND:A large proportion of patients with heart failure (HF) have a large and poorly contracting left ventricle. The noninvasive recognition of the ischemic etiology of such patients is difficult, and for this purpose, usually patients undergo coronary angiography. It has been shown that cardiovascular magnetic re...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2005.03.068

    authors: Casolo G,Minneci S,Manta R,Sulla A,Del Meglio J,Rega L,Gensini G

    更新日期:2006-01-01 00:00:00

  • Clinical and electrophysiologic characteristics of sinoatrial entrance block evaluated by direct sinus node electrography: prevalence, relation to antegrade sinoatrial conduction time, and relevance to sinus node disease.

    abstract::When AV conduction is normal, the absence of VA conduction is not abnormal. Analogous information about retrograde sinoatrial conduction is not available. Although the premature atrial stimulas (PAS) technique can demonstrate the presence of sinoatrial entrance block (SAEB), both its prevalence and its relationship to...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(81)90484-1

    authors: Reiffel JA,Gang E,Livelli F Jr,Gliklich J,Bigger JT Jr

    更新日期:1981-12-01 00:00:00

  • Two forms of hypertrophic cardiomyopathy distinguished by inheritance of HLA haplotypes and left ventricular outflow tract obstruction.

    abstract::In this study we have performed human leukocyte antigen (HLA)-A and B typing on nine patients with hypertrophic cardiomyopathy (HCM) and their relatives. Four patients had relatives who also had the disease. HLA typing of the familial form of HCM revealed a very close association of a given HLA-A,B haplotype with the ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(83)90401-5

    authors: Kishimoto C,Kaburagi T,Takayama S,Yokoyama S,Hanyu I,Takatsu Y,Tomimoto K

    更新日期:1983-06-01 00:00:00

  • Effects of peripheral blood stem cell mobilization with granulocyte-colony stimulating factor and their transcoronary transplantation after primary stent implantation for acute myocardial infarction.

    abstract:BACKGROUND:There is increasing evidence that transplantation of autologous stem cells improves cardiac function after acute myocardial infarction (AMI). For propagation of peripheral blood stem cells (PBSCs), application of granulocyte-colony stimulating factor (G-CSF) has been shown to be feasible, effective, and safe...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.ahj.2006.03.012

    authors: Steinwender C,Hofmann R,Kammler J,Kypta A,Pichler R,Maschek W,Schuster G,Gabriel C,Leisch F

    更新日期:2006-06-01 00:00:00

  • Heart rate variability in cocaine-exposed newborn infants.

    abstract:BACKGROUND:Infants born to cocaine-using mothers have a 3- to 8-fold increase in sudden infant death syndrome. Its underlying cause, in part, may be attributed to abnormal autonomic function. We proposed to study heart rate variability, reflecting autonomic control of the heart, in cocaine-exposed infants. METHODS:Fro...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2001.118112

    authors: Mehta SK,Super DM,Salvator A,Singer L,Connuck D,Fradley LG,Harcar-Sevcik RA,Kaufman ES

    更新日期:2001-11-01 00:00:00

  • Aging and pain perception in ischemic heart disease.

    abstract::Age is a recognized risk factor for coronary artery disease, but the relationship between age and silent ischemia is not well understood. We analyzed the data from 35 rest/stress radionuclide ventriculography examinations in patients with documented ischemic coronary artery disease who had experienced 1 mm ST segment ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(90)90156-r

    authors: Miller PF,Sheps DS,Bragdon EE,Herbst MC,Dalton JL,Hinderliter AL,Koch GG,Maixner W,Ekelund LG

    更新日期:1990-07-01 00:00:00

  • Holter-guided identification of premature ventricular contractions susceptible to suppression by beta-blockers.

    abstract::To evaluate whether the identification of the different types of relations between premature ventricular contractions (PVCs) and the preceding sinus cycle length is capable of predicting the effect of beta-blockers on the PVCs themselves, 55 patients (43 men, 12 women, mean age 52.6 +/- 15.6 years) with different card...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0002-8703(96)90529-3

    authors: Pitzalis MV,Mastropasqua F,Massari F,Totaro P,Di Maggio M,Rizzon P

    更新日期:1996-03-01 00:00:00

  • Hemodynamic, renal, and neurohumoral effects of a selective oral DA1 receptor agonist (fenoldopam) in patients with congestive heart failure.

    abstract::Fenoldopam mesylate (SK&F 82526-J) is a novel benzazepine derivative. It has selective agonist activity at post-junctional (DA1) vascular dopaminergic receptors, which normally subserve renal artery vasodilation. Previous studies in normal subjects and in patients with hypertension indicate that fenoldopam increases r...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(88)90620-5

    authors: Francis GS,Wilson BC,Rector TS

    更新日期:1988-08-01 00:00:00

  • Study design for the Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care (IMMEDIATE) Trial: A double-blind randomized controlled trial of intravenous glucose, insulin, and potassium for acute coronary syndr

    abstract:BACKGROUND:Experimental studies suggest that metabolic myocardial support by intravenous (IV) glucose, insulin, and potassium (GIK) reduces ischemia-induced arrhythmias, cardiac arrest, mortality, progression from unstable angina pectoris to acute myocardial infarction (AMI), and myocardial infarction size. However, tr...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2012.02.002

    authors: Selker HP,Beshansky JR,Griffith JL,D'Agostino RB,Massaro JM,Udelson JE,Rashba EJ,Ruthazer R,Sheehan PR,Desvigne-Nickens P,Rosenberg YD,Atkins JM,Sayah AJ,Aufderheide TP,Rackley CE,Opie LH,Lambrew CT,Cobb LA,Macleod BA

    更新日期:2012-03-01 00:00:00

  • Subclinical coronary atherosclerosis: racial profiling is necessary!

    abstract:OBJECTIVES:We aim to review the studies comparing coronary calcification across different ethnic groups. BACKGROUND:There is still uncertainty regarding ethnic differences in the prevalence, progression, and risk of coronary artery disease. Clues to possible racial differences in rates of coronary heart disease (CHD) ...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/j.ahj.2006.08.008

    authors: Orakzai SH,Orakzai RH,Nasir K,Santos RD,Edmundowicz D,Budoff MJ,Blumenthal RS

    更新日期:2006-11-01 00:00:00

  • Lifestyle changes and 14-year change in high-density lipoprotein cholesterol in a cohort of male physicians.

    abstract:BACKGROUND:Although cross-sectional studies have identified lifestyle factors associated with high-density lipoprotein cholesterol (HDL-C), no studies have examined the association between changes in lifestyle factors and long-term changes in HDL-C. METHODS:We examined the association between changes in lifestyle fact...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2010.12.015

    authors: Rahilly-Tierney C,Sesso HD,Djoussé L,Gaziano JM

    更新日期:2011-04-01 00:00:00

  • Effects of carvedilol therapy on restrictive diastolic filling pattern in chronic heart failure.

    abstract:BACKGROUND:Carvedilol therapy during congestive heart failure demonstrated a good efficacy in mortality rate reduction and in improvement of left ventricular (LV) systolic performance. However, currently there is not any finding about the drug's effect on diastolic filling. The aim of this study was to evaluate the eff...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-8703(03)00525-8

    authors: Palazzuoli A,Carrera A,Calabria P,Puccetti L,Pastrorelli M,Pasqui AL,Auteri A,Bruni F

    更新日期:2004-01-01 00:00:00

  • Transient appearance of collaterals during vasospastic occlusion in patients without obstructive coronary atherosclerosis.

    abstract::Coronary angiography of both right and left coronary arteries, using the Sones technique, was performed during the attack of total spastic obstruction in 11 patients with clinically documented history of variant angina. None of the patients had more than 70% stenosis of organic atherosclerosis in any coronary artery a...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(85)90635-0

    authors: Matsuda Y,Ogawa H,Moritani K,Matsuda M,Katayama K,Fujii T,Kohno M,Miura T,Kohtoku S,Kusukawa R

    更新日期:1985-04-01 00:00:00

  • Ancrod decreases the frequency of cyclic flow variations and causes thrombolysis following acute coronary thrombosis.

    abstract::The potential use of ancrod, a purified isolate from the venom of the Malaysian pit viper, Agkistrodon rhodostoma, in decreasing the frequency of cyclic flow variations in severely stenosed canine coronary arteries and causing thrombolysis of an acute coronary thrombus induced by a copper coil was evaluated. Open-ches...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(87)90050-0

    authors: Apprill PG,Ashton J,Guerrero J,Glas-Greenwalt P,Buja LM,Willerson JT

    更新日期:1987-04-01 00:00:00

  • Noninvasive determination of endothelium-mediated vasodilation as a screening test for coronary artery disease: pilot study to assess the predictive value in comparison with angina pectoris, exercise electrocardiography, and myocardial perfusion imaging.

    abstract:BACKGROUND:Peripheral endothelial dysfunction (ED) quantified by the determination of flow-mediated dilation (FMD%) of the brachial artery with the use of high-resolution ultrasound is an early marker of atherosclerosis. Although a positive correlation with coronary artery disease (CAD) has been reported, the unanswere...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(99)70189-4

    authors: Schroeder S,Enderle MD,Ossen R,Meisner C,Baumbach A,Pfohl M,Herdeg C,Oberhoff M,Haering HU,Karsch KR

    更新日期:1999-10-01 00:00:00

  • Effect of exercise training on ventricular function, dyssynchrony, resting myocardial perfusion, and clinical outcomes in patients with heart failure: a nuclear ancillary study of Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Tra

    abstract:BACKGROUND:Technetium Tc 99m gated single photon emission computed tomography (SPECT) has become the cornerstone of noninvasive risk stratification in patients with ischemic heart disease, but its role in patients with heart failure is not as well established. STUDY DESIGN:This study is a substudy of the Heart Failure...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2007.03.045

    authors: Bensimhon DR,Adams GL,Whellan DJ,Pagnanelli RA,Trimble M,Lee BA,Lee KL,Ellis SJ,Kraus WE,Rendall DS,Iskandrian AE,O'Connor CM,Borges-Neto S,HF-ACTION Trial Investigators.

    更新日期:2007-07-01 00:00:00

  • Relationship between exercise echocardiography and perfusion single-photon emission computed tomography in patients with single-vessel coronary artery disease.

    abstract::The aim of this study was to assess the relative value of exercise echocardiography and perfusion single-photon emission computed tomography (SPECT) in identifying the presence and severity of coronary artery stenosis. Accordingly, 44 consecutive patients with stenosis in one vessel performed simultaneous postexercise...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(92)90922-i

    authors: Salustri A,Pozzoli MM,Hermans W,Ilmer B,Cornel JH,Reijs AE,Roelandt JR,Fioretti PM

    更新日期:1992-07-01 00:00:00

  • Clinical profile and outcome of restrictive cardiomyopathy in children.

    abstract::The clinical profile and outcome of idiopathic restrictive cardiomyopathy in a group of eight children are reviewed. There were six girls and two boys. Age at presentation was 4.0 +/- 2.6 years (range 1.3 to 9.5 years). All patients had evidence of congestive heart failure with systemic venous congestion. Right or lef...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(92)90814-c

    authors: Lewis AB

    更新日期:1992-06-01 00:00:00

  • Drinking and coronary heart disease: the Albany Study.

    abstract::The relation of alcohol consumption to coronary heart disease (CHD) was examined in a cohort of 1910 employed men aged 38 to 55 years enrolled in the Albany Study, a prospective investigation of factors related to cardiovascular disease. Two follow-up periods were examined, one between 1953-54 and 1971-72, the other a...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(85)90152-8

    authors: Gordon T,Doyle JT

    更新日期:1985-08-01 00:00:00

  • Quinidine therapy in hospitalized patients with ventricular arrhythmias.

    abstract::Quinidine serum levels and pharmacokinetic data were assessed during steady state therapy with oral quinidine sulfate in 19 hospitalized patients who were being treated for ventricular arrhythmias. A new high performance liquid chromatography assay was employed. Four patients were studied both after the first dose of ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(79)90467-8

    authors: Carliner NH,Crouthamel WG,Fisher ML,Mugmon MA,Vassar DL,Narang PK,Plotnick GD

    更新日期:1979-12-01 00:00:00

  • Abnormal quinidine binding in survivors of prehospital cardiac arrest.

    abstract::Quinidine binding was studied in 15 survivors of prehospital cardiac arrest and was compared to 18 normal individuals and 20 patients with coronary artery disease. The unbound quinidine fraction was 6.3 +/- 2.8% in the survivors of prehospital cardiac arrest, a value significantly lower than normal individuals (unboun...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(84)90312-0

    authors: Kessler KM,Lisker B,Conde C,Silver J,Ho-Tung P,Hamburg C,Myerburg RJ

    更新日期:1984-04-01 00:00:00

  • Computer analysis of exercise-induced changes in QRS duration in patients with angina pectoris and in normal subjects.

    abstract::Exercise-induced changes in QRS duration were assessed in 25 normal subjects and in 17 patients with stable ischemic heart disease. None had bundle branch block or were taking medications, and all patients had angina pectoris induced during the test. QRS duration and ST60 amplitude were measured by computer during res...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(86)90640-x

    authors: Ahnve S,Sullivan M,Myers J,Froelicher V

    更新日期:1986-05-01 00:00:00