Hemodynamic, renal, and neurohumoral effects of a selective oral DA1 receptor agonist (fenoldopam) in patients with congestive heart failure.

abstract：BACKGROUND:We evaluated the influence of peak respiratory exchange ratio (pRER), as an index of effort adequacy, on peak VO2 prognostic reliability in patients with chronic heart failure (CHF) and reduced exercise capacity, whose peak VO2 may be underestimated because of poor patient motivation. METHODS:A cardiopulmon...

journal_title：American heart journal

authors： Mezzani A,Corrà U,Bosimini E,Giordano A,Giannuzzi P

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:This study was designed to investigate the efficacy of alteplase double-bolus dosing compared with the front-loaded 90-minute infusion regimen in patients with acute myocardial infarction. Recent pilot studies have suggested that bolus dosing may provide improved efficacy in establishing early, complete, and...

journal_title：American heart journal

authors： Bleich SD,Adgey AA,McMechan SR,Love TW

更新日期：1998-10-01 00:00:00

abstract：:Nitrates are widely used for the management of congestive heart failure (CHF), as well as angina pectoris. In both situations, nitrates significantly increase exercise capacity. The mechanism of this beneficial effect is unclear, especially in CHF. Isosorbide dinitrate reduces pulmonary capillary wedge pressure (PCWP)...

journal_title：American heart journal

authors： Franciosa JA

更新日期：1985-07-01 00:00:00

abstract：:The effects of lorcainide, a new antiarrhythmic drug, on serum electrolytes and osmolality are described in a series of 33 patients with organic heart disease and complex ventricular arrhythmias treated with lorcainide. In eight patients, a mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L was observed after a single 2...

journal_title：American heart journal

authors： Somani P,Temesy-Armos PN,Leighton RF,Goodenday LS,Fraker TD Jr

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Whether low-molecular-weight heparin (LMWH) is superior to unfractionated heparin (UFH) in acute ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) with drug-eluting stents (DESs) remains unclear. METHODS:A total of 3,372 STEMI patients wh...

journal_title：American heart journal

authors： Li YJ,Rha SW,Chen KY,Poddar KL,Jin Z,Minami Y,Wang L,Dang Q,Li GP,Ramasamy S,Park JY,Choi CU,Kim JW,Kim EJ,Park CG,Seo HS,Oh DJ,Jeong MH,Ahn YK,Hong TJ,Park JS,Kim YJ,Hur SH,Seong IW,Chae JK,Cho MC,Bae

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Platelet inhibition is critical in reducing both short- and long-term atherothrombotic risks after acute myocardial infarction (MI), especially among patients managed with percutaneous coronary intervention (PCI). Currently available antiplatelet medications, including adenosine diphosphate (ADP) receptor in...

journal_title：American heart journal

authors： Chin CT,Wang TY,Anstrom KJ,Zhu B,Maa JF,Messenger JC,Ryan KA,Davidson-Ray L,Zettler M,Effron MB,Mark DB,Peterson ED

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Previous research suggests that after coronary artery bypass graft (CABG) surgery, women fare worse than men. This study investigates sex differences in depression during recovery from CABG surgery. METHODS:We followed 137 patients (72 men, 65 women) undergoing elective isolated first CABG surgery between J...

journal_title：American heart journal

authors： Mitchell RH,Robertson E,Harvey PJ,Nolan R,Rodin G,Romans S,Abramson BL,Brister SJ,Ivanov J,Stewart DE

更新日期：2005-11-01 00:00:00

abstract：:To test the feasibility of synchronized retroperfusion (SRP) as a support device of percutaneous transluminal coronary angioplasty (PTCA) for high-risk patients, 10 patients with left main trunk or near left main trunk obstruction underwent PTCA with SRP. An 8.5F retroperfusion catheter was inserted from the antecubit...

journal_title：American heart journal

authors： Nanto S,Nishida K,Hirayama A,Mishima M,Komamura K,Masai M,Sakakibara T,Kodama K

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Heart failure still maintains a high mortality. Biomarkers reflecting different pathophysiological pathways are under evaluation to better stratify the mortality risk. The objective was to assess high-sensitivity cardiac troponin T (hs-cTnT) in combination with N-terminal pro-B type natriuretic peptide (NT-p...

journal_title：American heart journal

authors： de Antonio M,Lupon J,Galan A,Vila J,Urrutia A,Bayes-Genis A

更新日期：2012-05-01 00:00:00

abstract：:A new mechanically rotated 20 MHz intravascular ultrasound guide wire (0.032 inch) with a transducer core was placed through the central lumen of a peripheral arterial balloon-expandable stent. Using an anesthetized canine model, 11 stents were then deployed into the iliac or femoral arteries. Eight stents were succes...

journal_title：American heart journal

authors： Tenaglia AN,Kisslo K,Kelly S,Hamm MA,Crowley R,Davidson CJ

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:The impact of valve prosthesis-patient mismatch on long-term outcome after aortic valve replacement estimated by various variables such as projected indexed effective orifice area and internal geometric orifice area obtained from in vivo or in vitro published data is still controversial. METHODS:The effecti...

journal_title：American heart journal

authors： Florath I,Albert A,Rosendahl U,Ennker IC,Ennker J

更新日期：2008-06-01 00:00:00

abstract：:Repetitive 10-hour ECG recordings of 289 patients obtained within a year after myocardial infarction were analyzed for the presence of ventricular runs, and their association with various types of ventricular ectopic activity (VEA), average rate of premature ventricular complexes (PVCs), and coupling interval of PVCs ...

journal_title：American heart journal

authors： Thanavaro S,Kleiger RE,Miller JP,Province MA,Friedman E,Oliver GC

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Heparin is ubiquitously used in cardiac catheterization but predisposes to the development of heparin-induced thrombocytopenia. The objective was to examine prospectively the prevalence of anti-platelet factor 4 (PF4)/heparin antibodies and heparin-induced thrombocytopenia in the population undergoing cardia...

journal_title：American heart journal

authors： Foo SY,Everett BM,Yeh RW,Criss D,Laposata M,Van Cott EM,Jang IK

更新日期：2006-08-01 00:00:00

abstract：:Sudden cardiac death syndrome remains a major health problem responsible for approximately 400,000 deaths annually in the US. Effective therapies exist but are costly and are associated with potential complications. Currently used strategies for selection of the best candidates for implantable cardioverter defibrillat...

journal_title：American heart journal

authors： Kusmirek SL,Gold MR

更新日期：2007-04-01 00:00:00

abstract：:Left circumflex coronary blood flow was increased significantly (20 per cent) during stimulation of somatic afferent fibers. The change in CBF was associated with significant increases in heart rate and arterial pressure and significant decrease in coronary vascular resistance. Controlling heart rate or preventing car...

journal_title：American heart journal

authors： Kline RL

更新日期：1979-07-01 00:00:00

abstract：:To evaluate the antiischemic effects of intravenous milrinone, 20 patients with angiographically proved coronary artery disease and stable angina were studied at rest and during exercise under control conditions and after an intravenous loading injection of milrinone (50 micrograms/kg/10 min) followed by an infusion w...

journal_title：American heart journal

authors： Mitrovic V,Stöhring R,Schlepper M

更新日期：1991-06-01 00:00:00

abstract：AIM:The aim of the study was to assess and compare the safety of antiarrhythmic drugs (AADs) in an unselected real-world population of patients with atrial fibrillation (AF). METHODS AND RESULTS:This is a study of all patients with diagnosed AF in the Swedish Patient register who filled a prescription for sotalol, ami...

journal_title：American heart journal

authors： Friberg L

更新日期：2018-11-01 00:00:00

abstract：:The effects of alcohol intake on serum lipids and lipoproteins depend on the dose and mode of alcohol intake, individual susceptibility, genetic variables, and dietary factors. Therefore the changes of lipoprotein pattern are different among moderate and heavy drinkers. Moderate intake of alcohol increases the concent...

journal_title：American heart journal

authors： Taskinen MR,Nikkilä EA,Välimäki M,Sane T,Kuusi T,Kesäniemi A,Ylikahri R

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Many chronic heart failure (CHF) patients have low vitamin D (VitD) and high plasma renin activity (PRA), which are both associated with poor prognosis. Vitamin D may inhibit renin transcription and lower PRA. We investigated whether vitamin D3 (VitD3) supplementation lowers PRA in CHF patients. METHODS AND...

journal_title：American heart journal

authors： Schroten NF,Ruifrok WP,Kleijn L,Dokter MM,Silljé HH,Lambers Heerspink HJ,Bakker SJ,Kema IP,van Gilst WH,van Veldhuisen DJ,Hillege HL,de Boer RA

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Practice guidelines for patients with non-ST-segment elevation (NSTE) acute coronary syndromes (ACS) recommend targeting evidence-based therapies for the highest-risk patients. We characterized guideline adherence for NSTE ACS by risk status. METHODS:We analyzed inhospital treatments and outcomes for 77760 ...

journal_title：American heart journal

authors： Roe MT,Peterson ED,Newby LK,Chen AY,Pollack CV Jr,Brindis RG,Harrington RA,Christenson RH,Smith SC Jr,Califf RM,Braunwald E,Gibler WB,Ohman EM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Female sex independently predicts bleeding risk after percutaneous coronary intervention (PCI). Bivalirudin is safer than abciximab plus heparin in patients with non-ST-segment elevation myocardial infarction (NSTEMI). Thus, a greater benefit of bivalirudin in women would be expected. METHODS:We performed a...

journal_title：American heart journal

authors： Mehilli J,Neumann FJ,Ndrepepa G,King L,Schulz S,Maimer Rodrigues da Cunha F,Jochheim D,Byrne RA,Hausleiter J,Ott I,Massberg S,Kastrati A,Pache J

更新日期：2013-04-01 00:00:00

abstract：:Angina pectoris before and after MI was evaluated in a sample of 729 men and women from a general population in whom MI developed during a 36-year period of follow-up. Relations of AP to subsequent CHD events and mortality after initial MI were analyzed by proportional hazards regression models and were adjusted for c...

journal_title：American heart journal

authors： Brand FN,Larson M,Friedman LM,Kannel WB,Castelli WP

更新日期：1996-07-01 00:00:00

abstract：:We evaluated the usefulness of peripherally injected sonicated albumin microbubbles in transesophageal echo-Doppler cardiographic assessment of the left atrial appendage in 19 patients (age 61 +/- 19 [range 21 to 86] years; 12 [63%] women). Multiplane transesophageal echocardiography was performed before and after int...

journal_title：American heart journal

authors： Yao SS,Ilercil A,Meisner JS,Strom JA,Shirani J

更新日期：1997-04-01 00:00:00

abstract：:Plasma catecholamine levels were determined in 26 cases of uncomplicated myocardial infarction within 24 hours of onset of acute chest pain. Blood samples were collected at time of entry and at 4-hour intervals during the 48 hours following admission. Average values of plasma catecholamines within 1 hour of onset of p...

journal_title：American heart journal

authors： Nadeau RA,de Champlain J

更新日期：1979-11-01 00:00:00

abstract：:In order to correlate the antiarrhythmic and electrophysiological effects of disopyramide phosphate during acute myocardial ischemia, we performed experiments in 17 mongrel dogs. Refractory periods obtained by the extrastimulus method and conduction times recorded from local electrograms were determined in potentially...

journal_title：American heart journal

authors： Levites R,Anderson GJ

更新日期：1979-09-01 00:00:00

abstract：:Baroreflex modulation of forearm vascular resistance (FVR) has been reported to be abnormal in patients with congestive heart failure (CHF). However, the neurohumoral mechanisms for this impairment are not defined. We assessed the responses of arterial pressure, FVR, plasma norepinephrine, and plasma renin activity to...

journal_title：American heart journal

authors： Mohanty PK,Arrowood JA,Ellenbogen KA,Thames MD

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Stroke in patients with heart failure is associated with poor outcomes. Risk stratification schemes may improve clinical decision making in this patient population. This study investigated whether female sex is a risk factor for stroke in patients with heart failure in sinus rhythm. METHODS:This is a popula...

journal_title：American heart journal

authors： Melgaard L,Gorst-Rasmussen A,Lip GY,Rasmussen LH,Larsen TB

更新日期：2015-03-01 00:00:00

abstract：:Twenty-six patients with Ebstein's anomaly were classified into three types according to their clinical features, heart catheterization data, angiocardiographic and anatomical findings which were obtained on surgery or autopsy. The hemodynamics in each type were discussed. 1. Tricuspid Stenosis Dominant Type. Eight pa...

journal_title：American heart journal

authors： Takayasu S,Obunai Y,Konno S

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Although more than one million patients in the United States have permanent pacemakers, little is known about their cause of death. We evaluated the cause of death in 404 patients who died in the Mode Selection Trial (MOST). METHODS:In MOST, patients received a dual-chamber pacemaker randomly programmed to ...

journal_title：American heart journal

authors： Flaker G,Greenspon A,Tardiff B,Schron E,Goldman L,Hellkamp A,Lee K,Lamas G,Mode Selection Trial (MOST) Investigators.

更新日期：2003-11-01 00:00:00

abstract：:Patients with impaired glucose tolerance (IGT) have increased risk for developing type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Lifestyle modification and medication can prevent or delay progression to diabetes (PD), but whether such interventions also reduce the risk of CVD has not been rigorously...

journal_title：American heart journal

authors： Califf RM,Boolell M,Haffner SM,Bethel M,McMurray J,Duggal A,Holman RR,NAVIGATOR Study Group.

更新日期：2008-10-01 00:00:00