Abstract:
:Sudden cardiac death syndrome remains a major health problem responsible for approximately 400,000 deaths annually in the US. Effective therapies exist but are costly and are associated with potential complications. Currently used strategies for selection of the best candidates for implantable cardioverter defibrillator (ICD) therapy are imperfect and leave a large number of high-risk patients unprotected. At the same time, many patients who received ICDs will never develop tachyarrhythmia and require ICD intervention. The article summarizes the current status and applicability of the noninvasive and invasive tests used for sudden cardiac death risk assessment with the emphasis on the increasingly recognized value of microvolt T wave alternans.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Kusmirek SL,Gold MRdoi
10.1016/j.ahj.2007.01.024subject
Has Abstractpub_date
2007-04-01 00:00:00pages
25-33issue
4 Suppleissn
0002-8703issn
1097-6744pii
S0002-8703(07)00083-Xjournal_volume
153pub_type
杂志文章,评审abstract::Reductions in mobility and cognitive function linked to accrual of brain microvascular disease related white matter hyperintensities (WMHs) on magnetic resonance imaging can occur in older hypertensive patients in as little as 2 years. We have designed a trial evaluating 2 levels of ambulatory blood pressure (ABP) con...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2012.11.008
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:The left atrium is afterload sensitive, responding to immediate changes in left ventricular (LV) diastolic pressure, and left atrial volumetric remodeling has been reported in conditions associated with abnormal diastolic function. We examined the relationship between left atrial volumetric remodeling and ob...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.07.017
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Intracranial hemorrhage is an uncommon but very dangerous complication in patients receiving thrombolytic therapy for acute myocardial infarction. Neurosurgical evacuation is often an available treatment option. However, the association between neurosurgical evacuation and clinical outcomes in these patients...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-8703(99)70152-3
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:Compared with men, women have more evidence of myocardial ischemia with no obstructive coronary artery disease. Although low endogenous estrogen levels are associated with endothelial dysfunction, the role of low-dose hormone therapy has not been fully evaluated. We postulate that a 12-week duration of low-d...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2010.03.024
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:With one-quarter of initial myocardial infarctions (MI) being unrecognized MI (UMI), recognition is critical to minimize further cardiovascular risk. Diabetes mellitus is an established risk factor for UMI. If impaired fasting glucose (IFG) also increased the risk for UMI, it would represent a significant pu...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2015.08.003
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:In adults with an atrial septal defect (ASD) transcatheter closure leads to an improvement of peak oxygen uptake (VO2), but the kinetics of recovery of VO2 after maximal exercise in this patient population and the impact of transcatheter ASD closure have never been investigated. METHODS:Twenty consecutive p...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2003.11.013
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Prior studies regarding the effect of racial status on post-myocardial infarction (MI) in subjects with diabetes have yielded conflicting results. We evaluated the effect of diabetes status on racial differences in post-MI mortality and morbidity for a 7-year period, from 1990 through 1997. METHODS:All pati...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.02.042
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:AutoCapture (AC) is a programmable feature that enables the pacemaker to both track the capture threshold and automatically adjust the output on a beat-by-beat basis. Although AC safely and significantly reduces the current drainage, some authors have argued that the longevity benefit of such a system is ove...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(03)00529-5
更新日期:2004-01-01 00:00:00
abstract::The response of S1 amplitude to exercise stress was investigated in patients with coronary heart disease. Phonocardiograms were recorded at rest and during a multistage bicycle ergometer exercise test in a group of 22 patients with angina pectoris and documented coronary disease, and in a normal control group comprise...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(75)90461-5
更新日期:1975-12-01 00:00:00
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journal_title:American heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1067/mhj.2002.120775
更新日期:2002-04-01 00:00:00
abstract::A new integrated method for quantitating temporal and spatial systolic wall motion heterogeneity was developed and applied in 15 normal subjects and 26 patients with previous myocardial infarction (MI). After frame by frame digitizing, right anterior oblique left cineventriculograms (LV) were analyzed with 90 spaced r...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(86)90465-5
更新日期:1986-10-01 00:00:00
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journal_title:American heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/S0002-8703(03)00227-8
更新日期:2003-09-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(84)90745-2
更新日期:1984-11-01 00:00:00
abstract:BACKGROUND:Elevations of creatine kinase-MB (CK-MB) and cardiac troponin T (cTnT) have an uncertain long-term prognostic value after coronary artery bypass graft (CABG) surgery. We aimed to test the hypothesis that CK-MB and cTnT are predictors of long-term survival after CABG and to assess which of these 2 biomarkers ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2012.05.027
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:Chest pain in the absence of obstructive coronary artery disease (CAD) is common in women; it is frequently associated with debilitating symptoms and repeated evaluations and may be caused by coronary microvascular dysfunction. However, the prevalence and determinants of microvascular dysfunction in these wo...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2001.114198
更新日期:2001-05-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90272-j
更新日期:1991-12-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2020.06.012
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The diagnostic value of 12-lead electrocardiography during dobutamine stress echocardiography (DSE) is not well documented. METHODS AND RESULTS:We reviewed the records of 116 patients referred for DSE and coronary angiography, 52 of whom were excluded because of abnormal ST segment or inadequate DSE. Of the...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(98)70163-2
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:Previous studies have suggested that thrombolysis is used less often in blacks than in whites. However, whether the greater prevalence of contraindications or less specific electrocardiographic manifestations of myocardial infarction (MI) account for this difference is unclear. METHODS AND RESULTS:We studie...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2000.107173
更新日期:2000-08-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2011.07.011
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Previous studies have demonstrated that the adenosine monophosphate deaminase 1 (AMPD1) C34T polymorphism may be associated with survival in cardiac populations with a protective effect of the T allele. However, these studies included limited number of patients with few cardiovascular events. METHODS:We pro...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2006.04.003
更新日期:2006-10-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2000.107997
更新日期:2000-08-01 00:00:00
abstract::Four hundred and ninety-two patients with coronary artery disease underwent analysis of their electrocardiograms, coronary arteriograms, and ventriculograms. Significant Q-waves were correlated with critical coronary occlusions (greater than or equal 75 per cent obstruction) and ventricular contractility. It was found...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(75)90425-1
更新日期:1975-10-01 00:00:00
abstract:BACKGROUND:Chronic infection with Chlamydia pneumoniae (Cpn) has been associated with atherosclerotic cardiovascular disease in sero-epidemiological, pathological and animal-model studies. Inflammation and immune activation has been proposed as the pathophysiological link between chronic infection and atherosclerosis. ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/S0002-8703(03)00101-7
更新日期:2003-07-01 00:00:00
abstract::Forty-eight patients with predominant aortic stenosis underwent His bundle electrography (HBE) at the time of diagnostic catheterization. Patients were divided into four groups based upon severity of calcification of the aortic valve fluoroscopically as judged independently by three angiographers. Of 48 patients, thre...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(85)90514-9
更新日期:1985-07-01 00:00:00
abstract:BACKGROUND:Procoagulant stress responses may contribute to atherosclerosis development and acute coronary thrombosis. In the present study, we examined the role of beta2-adrenergic receptor function and plasma catecholamines in the stress-induced increase in the 2 hypercoagulability markers thrombin-antithrombin III (T...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2002.123146
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:All patients who present to an emergency department (ED) are triaged. The ED triage score may determine when patients are seen by a physician. Half of patients with acute myocardial infarction (AMI) were given a low priority score in Ontario in 2000/2001. We assessed the appropriateness of ED triage and its ...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2011.05.015
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:The aim of this study was to compare rate of onset, magnitude, and consistency of platelet inhibition after administration of prasugrel or clopidogrel and to relate platelet inhibition to systemic exposure to each active metabolite. Thienopyridines are prodrugs, metabolized in vivo to active metabolites that...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2006.10.010
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:Our purpose was to determine the effect of postoperative beta-blocker withdrawal on mortality and cardiovascular events after vascular surgery. METHODS:Detailed data were collected on perioperative cardiovascular medication use and discontinuation and cardiovascular risk factors among consecutive major vascu...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2001.111547
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Cohort studies have suggested little effect of coffee consumption on risk of acute myocardial infarction. The effect of coffee consumption on prognosis after myocardial infarction is uncertain. METHODS:In a population-based inception cohort study, we followed 1,369 patients hospitalized with a confirmed fir...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2008.11.009
更新日期:2009-03-01 00:00:00