Abstract:
:A new integrated method for quantitating temporal and spatial systolic wall motion heterogeneity was developed and applied in 15 normal subjects and 26 patients with previous myocardial infarction (MI). After frame by frame digitizing, right anterior oblique left cineventriculograms (LV) were analyzed with 90 spaced radii. For each radius shortening fractions at sequential systolic time points relative to end diastole were correlated with corresponding normalized time points using linear regression method, yielding the radial correlation coefficient (r) and the radial regression slope (b) for temporal and spatial information. High radial r values with small standard deviations were observed in normal LV (0.972 +/- 0.016) and in non-MI regions (0.964 +/- 0.018), indicating temporally homogeneous radial shortening. A significant temporal heterogeneity in wall motion was demonstrated in MI regions (0.480 +/- 0.304) (p less than 0.001). In comparison with normal b values (0.449 +/- 0.106), there were decreased b values in MI regions (0.203 +/- 0.211) (p less than 0.001) and increased b values in non-MI regions (0.695 +/- 0.213) (p less than 0.001), suggesting hypokinetic and compensative hyperkinetic contraction in corresponding regions. Thus, temporal and spatial wall motion throughout systole could be assessed quantitatively by the present computer-assisted method with two simple integrated parameters.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Chen CG,Bonzel T,Just H,Seiffert G,Zeiher A,Kasper W,Wollschlaeger Hdoi
10.1016/0002-8703(86)90465-5subject
Has Abstractpub_date
1986-10-01 00:00:00pages
712-21issue
4eissn
0002-8703issn
1097-6744pii
0002-8703(86)90465-5journal_volume
112pub_type
杂志文章abstract::Reperfusion therapy has lowered the mortality in patients suffering acute myocardial infarction. Failure to reperfuse is associated with significantly higher risk of short- and long-term mortality. Detection of reperfusion is thus important. In a prospective pilot study, we used continuous on-line computerized vectorc...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90455-q
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVE:To analyze the effect of delay times on racial differences in thrombolysis for acute myocardial infarction. BACKGROUND:Lower rates of thrombolytic therapy in blacks with acute myocardial infarction have recently been reported, but the reasons for this disparity are unknown. We hypothesized that lower rates o...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2000.109644
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:The APEX trial assessed the safety and efficacy of extended-duration thromboprophylaxis using betrixaban versus standard dosing of enoxaparin among hospitalized, acutely ill medical patients. The 80-mg betrixaban dose was halved to 40 mg among subjects with severe renal insufficiency and those receiving a co...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2016.12.004
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Limited data are available on the care of patients with acute severe hypertension requiring hospitalization. We characterized contemporary practice patterns and outcomes for this population. METHODS:STAT is a 25-institution, US registry of consecutive patients with acute severe hypertension (>180 mm Hg syst...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2009.07.020
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Few data are available concerning the effects on clinical outcome and left ventricular function of abciximab administration in patients undergoing rescue percutaneous transluminal coronary angioplasty (PTCA) after failed thrombolysis for acute myocardial infarction. The aim of the study was to investigate su...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1067/mhj.2002.119762
更新日期:2002-02-01 00:00:00
abstract::Results of recent studies have suggested that routine cardiac catheterization may be unnecessary after reperfusion therapy for acute myocardial infarction. Therefore to better define the short-term prognostic value of early coronary angiography, and specifically the prognostic significance of multivessel coronary arte...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/0002-8703(91)90661-z
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND:The Amplatzer septal occluder (ASO) allows the percutaneous closure of small to very large atrial septal defects (ASDs). The CardioSEAL/STARflex (CS/SF) can be used only for closure of small to moderate ASDs (stretch size up to 18 mm). These 2 devices are widely used in clinical practice. Therefore, a compar...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.03.013
更新日期:2004-09-01 00:00:00
abstract::To examine the recovery time of left atrial mechanical function after electrical cardioversion of atrial fibrillation, we recorded transmitral flow, pulmonary venous flow velocities, and interatrial septal motion during atrial systole within 24 hours (16 +/- 5 hours) and 10 days after cardioversion in 25 patients with...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(96)90353-1
更新日期:1996-02-01 00:00:00
abstract::The medical records of 254 patients with atrial fibrillation were reviewed to determine the incidence of embolic events in relation to type of cardiovascular disease, duration of atrial fibrillation, and use of anticoagulants. During a total follow-up of 833 patient-years in atrial fibrillation, there were 32 instance...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(86)90318-2
更新日期:1986-11-01 00:00:00
abstract:CLINICAL SCENARIO:A 67-year-old man is referred to your cardiology clinic complaining of worsening angina and dyspnea on exertion. Physical examination reveals a harsh grade IV/VI late-peaking crescendo-decresendo systolic murmur, loudest at the upper sternal border. The aortic closure sound is diminished. Echocardiogr...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.05.031
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to examine ethnic differences in depressive symptoms and antidepressant treatment in a cohort of patients undergoing diagnostic coronary angiography. BACKGROUND:Coronary heart disease (CHD) is the leading cause of mortality in the United States, with an excess of mortality in African...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2008.08.013
更新日期:2009-01-01 00:00:00
abstract::Current antitachycardia systems are incapable of adequately distinguishing stable from unstable tachycardias. Previously, integration of a pressure sensor or an impedance sensor, together with electrogram analysis, has been investigated as an improved method of identifying unstable arrhythmias. A mixed venous oxygen s...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90519-n
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND:Endothelin 1 is a potent endogenous vasoconstrictor neurohormone, and endothelin 1 plasma concentrations predict adverse outcomes in patients with acute heart failure (AHF). Tezosentan, an intravenous endothelin receptor antagonist, improved hemodynamics in patients with AHF; however, its effects on morbidit...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.04.035
更新日期:2005-07-01 00:00:00
abstract::The QRS complex and ST segment in the ECGs of 80 patients who died of an acute myocardial infarction (MI) were studied in relation to the extent of the MI (subendocardial vs. transmural). Changes in the QRS complex developed in nine out of the 15 cases with an acute subendocardial MI. Five of these cases fulfilled the...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(79)90219-9
更新日期:1979-08-01 00:00:00
abstract::Three kinds of torso surface isopotential maps (measured, simulated, and difference maps) were delineated at every 1.5 (or 3) msec. during the QRS duration from the 85 unipolar lead ECG's led from the surface of a cylindrical torso model filled with perfusate and containing a canine heart undergoing Langendorff's perf...
journal_title:American heart journal
pub_type: 杂志文章
doi:
更新日期:1976-08-01 00:00:00
abstract:BACKGROUND:The activated coagulation time (ACT) is a rapid measurement of a patient's level of heparin anticoagulation during cardiac catheterization. Patients receiving warfarin therapy occasionally are seen at the catheterization laboratory for emergent procedures. The effects of warfarin on ACT activity have not bee...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(98)70223-6
更新日期:1998-09-01 00:00:00
abstract::Fenoldopam mesylate (SK&F 82526-J) is a novel benzazepine derivative. It has selective agonist activity at post-junctional (DA1) vascular dopaminergic receptors, which normally subserve renal artery vasodilation. Previous studies in normal subjects and in patients with hypertension indicate that fenoldopam increases r...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(88)90620-5
更新日期:1988-08-01 00:00:00
abstract::The efficacy and safety of sotalol therapy for ventricular arrhythmias was evaluated in 133 patients with drug-refractory ventricular arrhythmias. All patients had baseline electrophysiologic studies before and after oral sotalol therapy. Sixty-six patients were discharged home, treated with sotalol (52 patients witho...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(96)90008-3
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Standard gray-scale imaging (GSI), three-dimensional (3D) echocardiography has been shown to be superior to two-dimensional echocardiography in measuring left ventricular volume. However, the often relatively poor quality of transthoracic gray-scale data can limit the potential application of this technique....
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(98)70061-4
更新日期:1998-06-01 00:00:00
abstract::The appearance of perivalvular cavities (PCs) in patients with infectious endocarditis (IE) was studied by transesophageal echocardiography (TEE) color Doppler examinations to determine whether the color Doppler TEE presentation was in keeping with the current concept of PCs representing abscesses. Two heart centers p...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(95)90241-4
更新日期:1995-07-01 00:00:00
abstract::Affected members of early coronary pedigrees in Utah are at markedly increased risk for the development of clinical coronary heart disease (CHD). The relationship between the presence of coronary risk factors and the severity of angiographic coronary artery disease (CAD) in 53 members of high-risk Utah pedigrees was e...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(92)90635-9
更新日期:1992-02-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(89)90656-x
更新日期:1989-01-01 00:00:00
abstract::In this study of 14 patients hospitalized with a first event of myocardial infarction, maximal ST segment depression in precordial leads V2 and V3 was the sole ECG finding during chest pain in the first 24 hours of evolving posterolateral infarction, based upon further two-dimensional echocardiographic examination and...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(87)90916-1
更新日期:1987-05-01 00:00:00
abstract::Adenosine thallium stress testing has a demonstrated utility in the detection of coronary artery disease. The optimal dose for diagnostic efficacy with minimal side effects has not been critically evaluated. A randomized 3- and 6-minute infusion of adenosine (140 micrograms/kg/min) was performed in 11 subjects. Subjec...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-8703(07)80015-9
更新日期:1993-07-01 00:00:00
abstract::Clinically available automatic implantable defibrillators use a monophasic truncated exponential waveform shock; after delivery the charge remaining on the device's capacitors is "dumped" internally and wasted. The efficacy of a monophasic and biphasic truncated exponential defibrillation waveform produced by a single...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(89)90779-5
更新日期:1989-02-01 00:00:00
abstract:BACKGROUND:Heart failure (HF) remains a major public health issue. Data on long-term trends in the incidence of HF and survival after its onset are limited. METHODS:A prospective cohort study conducted between 1985 and 2004 in 21,906 participants of the Physicians' Health Study I who were alive and free of HF on Janua...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2007.07.004
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Half of patients with hypertension have poor blood pressure (BP) control. Recent models for treating hypertension have integrated disease monitoring and telephone-based interventions delivered in patients' homes. This study evaluated the costs of the Hypertension Intervention Nurse Telemedicine Study (HINTS)...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2012.03.016
更新日期:2012-06-01 00:00:00
abstract::The effects of captopril (CPT), an oral angiotensin-converting enzyme (ACE) inhibitor, on systemic failure (CHF). In 15 patients, CPT decreased mean arterial pressure from 75 +/- 3 to 60 +/- 3 mm Hg associated with a 16% increase in cardiac output, a 24% reduction in systemic vascular resistance, and a 36% decrease in...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(82)90052-7
更新日期:1982-11-01 00:00:00
abstract:BACKGROUND:Tailored Antiplatelet Initiation to Lessen Outcomes Due to Decreased Clopidogrel Response after Percutaneous Coronary Intervention (TAILOR-PCI) is the largest cardiovascular genotype-based randomized pragmatic trial (NCT#01742117) to evaluate the role of genotype-guided selection of oral P2Y12 inhibitor ther...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2020.10.069
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Current guidelines recommend anticoagulation therapy during primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI). However, whether anticoagulation should be continued after pPCI has not been well investigated. METHODS/DESIGN:The RIGHT trial is a prospectiv...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2020.06.005
更新日期:2020-09-01 00:00:00