Mixed venous oxygen saturation for differentiating stable from unstable tachycardias.

Abstract:

:Current antitachycardia systems are incapable of adequately distinguishing stable from unstable tachycardias. Previously, integration of a pressure sensor or an impedance sensor, together with electrogram analysis, has been investigated as an improved method of identifying unstable arrhythmias. A mixed venous oxygen saturation sensor was investigated for differentiating stable from unstable paced and induced tachycardias in 10 patients. During rapid pacing at 600, 500, 400, 350, 300, and 250 msec cycle lengths, mixed venous oxygen saturation decreased as cycle length decreased. For any given cycle length, rapid ventricular pacing tended to result in greater mixed venous oxygen desaturation compared with atrial pacing. Mixed venous oxygen saturation decreased similarly during induced ventricular tachycardias at cycle lengths greater than 230 msec. However, ventricular tachycardias at cycle lengths less than or equal to 230 msec and ventricular fibrillation had no effect on mixed venous oxygen saturation until after termination. Subsequently, a mixed venous oxygen saturation-tiered therapy algorithm (cycle length less than or equal to 230 msec = unstable; cycle length greater than 230 msec and MVO2 greater than or equal to 6% over 30 seconds = unstable) was developed and was tested retrospectively in 113 paced and induced tachyarrhythmias in these 10 patients for detecting unstable tachycardias (defined as a decrease from baseline systolic arterial pressure of greater than or equal to 50 mm Hg at 15 seconds). The mixed venous oxygen algorithm had 93% sensitivity and 96% specificity compared with rate-only (rate greater than or equal to 170 beats/min) detection with 93% sensitivity and 71% specificity.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

Am Heart J

journal_title

American heart journal

authors

Cohen TJ,Liem LB

doi

10.1016/0002-8703(91)90519-n

subject

Has Abstract

pub_date

1991-09-01 00:00:00

pages

733-40

issue

3 Pt 1

eissn

0002-8703

issn

1097-6744

pii

0002-8703(91)90519-N

journal_volume

122

pub_type

杂志文章
  • The impact of implantable cardioverter defibrillator therapy on health care systems.

    abstract::Implantable cardioverter defibrillators (ICDs) are now widely used for the secondary prevention of sudden cardiac death and are being offered as a primary preventive therapy. This technology has potential for significant fiscal impact on health care budgets. Technologic innovation will result in more complex devices t...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/0002-8703(94)90109-0

    authors: Saksena S

    更新日期:1994-04-01 00:00:00

  • Postinfarction ventricular arrhythmias in children.

    abstract::Because limited information is available on significant arrhythmias after myocardial infarction in pediatric patients, this study was performed to determine the incidence and impact of ventricular tachycardia or fibrillation on the postinfarction course in patients aged 1 day to 16 years. Review of 96 such children sh...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(95)90400-x

    authors: Johnsrude CL,Towbin JA,Cecchin F,Perry JC

    更新日期:1995-06-01 00:00:00

  • Kidney function and anemia as risk factors for coronary heart disease and mortality: the Atherosclerosis Risk in Communities (ARIC) Study.

    abstract:BACKGROUND:Kidney failure causes anemia and is associated with a very high risk of coronary heart disease (CHD). Mildly to moderately decreased kidney function is far more common and also is associated with an elevated prevalence of anemia and CHD risk. Recent data suggest an even higher risk of CHD when both condition...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2005.03.055

    authors: Astor BC,Coresh J,Heiss G,Pettitt D,Sarnak MJ

    更新日期:2006-02-01 00:00:00

  • Estimation of pressure gradients by auscultation: an innovative and accurate physical examination technique.

    abstract:BACKGROUND:Knowledge of pressure gradients across valves, arteries, and ventricular septal defects (VSD) is important in patient management. It was determined how well such gradients can be estimated by auscultation of a murmur's frequencies. METHODS:In 151 patients with pulmonary stenosis (PS) (n = 77), aortic stenos...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2001.113222

    authors: Phoon CK

    更新日期:2001-03-01 00:00:00

  • Peripheral hemodynamic effects of captopril in patients with congestive heart failure.

    abstract::In 14 patients with severe congestive heart failure, the effects of captopril on the forearm circulation were evaluated with strain gauge plethysmography. Changes in plasma renin activity, angiotensin II, norepinephrine, epinephrine, bradykinin, prostaglandin E2, and 6-keto-prostaglandin F1 alpha concentrations were a...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(89)90662-5

    authors: Nishimura H,Kubo S,Ueyama M,Kubota J,Kawamura K

    更新日期:1989-01-01 00:00:00

  • Isolated T wave alternans.

    abstract::Two patients with isolated T wave alternans are reported, with their vectocardiograms, their response to carotid sinus stimulation, and the response to calcium infusion in one of them with documented severe hypocalcemia. Eleven cases of the literature are briefly reviewed. The alternans of the T wave appears with seve...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(78)90369-1

    authors: Navarro-Lopez F,Cinca J,Sanz G,Periz A,Magriña J,Betriu A

    更新日期:1978-03-01 00:00:00

  • Effects of dexamethasone elution on tissue reaction around stimulating electrodes of endocardial pacing leads in dogs.

    abstract::A pair of endocardial pacemaker leads, identical except for the presence or absence of dexamethasone elution from the distal stimulating electrode, was implanted into the right ventricle of each of 12 dogs for either 3 weeks (n = six pairs) or 6 weeks (n = six pairs). Fibrous connective tissue sheaths (0.04 to 0.20 mm...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(89)90408-0

    authors: Radovsky AS,Van Vleet JF

    更新日期:1989-06-01 00:00:00

  • Meta-analysis: inhibition of renin-angiotensin system prevents new-onset atrial fibrillation.

    abstract:BACKGROUND:Epidemiologic studies suggest that inhibition of renin-angiotensin system with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may prevent development of atrial fibrillation (AF). OBJECTIVE:The objective of the study was to assess if there is significant indication for using angio...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.ahj.2006.01.007

    authors: Anand K,Mooss AN,Hee TT,Mohiuddin SM

    更新日期:2006-08-01 00:00:00

  • Reciprocal rhythm in patients with normal electrocardiogram: Evidence for dual conduction pathways.

    abstract::The present study refers to six patients in whom an A-V reciprocal rhythm could be documented; in four cases it took the form of sustained tachycardia. None of the patients showed any ECG feature of ventricular pre-excitation (PR interval of more than 0.12 sec. and normal QRS configuration). The extrastimulus method s...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(76)80427-9

    authors: Touboul P,Huerta F,Porte J,Delahaye JP

    更新日期:1976-01-01 00:00:00

  • The value of stress single photon emission computed tomography in patients without known coronary artery disease presenting with dyspnea.

    abstract:BACKGROUND:Dyspnea is a complex system with multiple etiologies, including myocardial ischemia ("anginal equivalent"). Few studies have examined the utility of stress testing to detect coronary artery disease in this setting. The purpose of this study was to examine the prevalence, severity, and prognostic value of per...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2006.03.002

    authors: Balaravi B,Miller TD,Hodge DO,Gibbons RJ

    更新日期:2006-09-01 00:00:00

  • Uncontrolled immune response in acute myocardial infarction: unraveling the thread.

    abstract::Recently, the theory that hyperinflammation is the body's primary response to potent stimulus has been challenged. Indeed, a deregulation of the immune system could be the cause of multiple organ failure. So far, clinicians have focused on the last steps of the inflammatory cascade. However, little attention has been ...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/j.ahj.2008.07.008

    authors: Bodi V,Sanchis J,Nunez J,Mainar L,Minana G,Benet I,Solano C,Chorro FJ,Llacer A

    更新日期:2008-12-01 00:00:00

  • Comparison of a new 3-item self-reported measure of adherence to medication with pharmacy claims data in patients with cardiometabolic disease.

    abstract:BACKGROUND:Less than half of patients with cardiometabolic disease consistently take prescribed medications. While health insurers and some delivery organizations use claims to measure adherence, most clinicians do not have access during routine interactions. Self-reported scales exist, but their practical utility is o...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2020.06.012

    authors: Lauffenburger JC,Fontanet CP,Isaac T,Gopalakrishnan C,Sequist TD,Gagne JJ,Jackevicius CA,Fischer MA,Solomon DH,Choudhry NK

    更新日期:2020-10-01 00:00:00

  • Factors associated with non-vitamin K antagonist oral anticoagulants for stroke prevention in patients with new-onset atrial fibrillation: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II).

    abstract:BACKGROUND:Several non-vitamin K antagonist oral anticoagulant (NOAC) alternatives to warfarin are available for stroke prevention in atrial fibrillation (AF). We aimed to describe the factors associated with selection of NOACs versus warfarin in patients with new onset AF. METHODS:The ORBIT-AF II study is a national,...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/j.ahj.2017.03.024

    authors: Steinberg BA,Shrader P,Thomas L,Ansell J,Fonarow GC,Gersh BJ,Hylek E,Kowey PR,Mahaffey KW,O'Brien EC,Singer DE,Peterson ED,Piccini JP,Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Investigato

    更新日期:2017-07-01 00:00:00

  • A randomized trial of prophylactic antiarrhythmic agents (amiodarone and sotalol) in patients with atrial fibrillation for whom direct current cardioversion is planned.

    abstract:UNLABELLED:Antiarrhythmic agents enhance maintenance of sinus rhythm (SR) after direct current cardioversion (DCC) for atrial fibrillation but there are few comparative trials. BACKGROUND:The aims of the study were (1) to establish whether patients successfully cardioverted to SR are more likely to stay in SR over 6 m...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2005.09.009

    authors: Vijayalakshmi K,Whittaker VJ,Sutton A,Campbell P,Wright RA,Hall JA,Harcombe AA,Linker NJ,Stewart MJ,Davies A,de Belder MA

    更新日期:2006-04-01 00:00:00

  • Optimized duration of clopidogrel therapy following treatment with the Endeavor zotarolimus-eluting stent in real-world clinical practice (OPTIMIZE) trial: rationale and design of a large-scale, randomized, multicenter study.

    abstract:BACKGROUND:Current recommendations for antithrombotic therapy after drug-eluting stent (DES) implantation include prolonged dual antiplatelet therapy (DAPT) with aspirin and clopidogrel ≥12 months. However, the impact of such a regimen for all patients receiving any DES system remains unclear based on scientific eviden...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2012.09.009

    authors: Feres F,Costa RA,Bhatt DL,Leon MB,Botelho RV,King SB 3rd,de Paula JE,Mangione JA,Salvadori D Jr,Gusmão MO,Castello H Jr,Nicolela E Jr,Perin MA,Devito FS,Marin-Neto JA,Abizaid A

    更新日期:2012-12-01 00:00:00

  • Ebstein's anomaly of the tricuspid valve and prolapse of the mitral valve.

    abstract::The hearts from 10 necropsy patients with Ebstein's anomaly of the tricuspid valve were examined for abnormalities of the mitral valve. Five patients were under 1 year of age and none had an abnormal mitral valve. The other five patients were ages 18 to 72 years (mean 36 years); all had focal fibrous thickening of the...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(81)90663-3

    authors: Cabin HS,Roberts WC

    更新日期:1981-02-01 00:00:00

  • The effects of the angiotensin-converting enzyme inhibitor imidapril on plasma plasminogen activator inhibitor activity in patients with acute myocardial infarction.

    abstract::This study sought to determine whether early treatment with angiotensin-converting enzyme (ACE) inhibitors in patients with acute myocardial infarction (AMI) is useful for the improvement of fibrinolytic function, as well as left ventricular function. This study was designed to examine the levels of plasma plasminogen...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-8703(97)80021-x

    authors: Oshima S,Ogawa H,Mizuno Y,Yamashita S,Noda K,Saito T,Sumida H,Suefuji H,Kaikita K,Soejima H,Yasue H

    更新日期:1997-11-01 00:00:00

  • Myocardial contractile reserve predicts improvement in left ventricular function after cardiac resynchronization therapy.

    abstract:BACKGROUND:Myocardial contractile reserve has been shown to provide important prognostic information in patients with heart failure. We hypothesized that myocardial contractile reserve would predict left ventricular (LV) reverse remodeling after cardiac resynchronization therapy (CRT). METHODS:Thirty-one consecutive p...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2007.07.035

    authors: Ypenburg C,Sieders A,Bleeker GB,Holman ER,van der Wall EE,Schalij MJ,Bax JJ

    更新日期:2007-12-01 00:00:00

  • Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies.

    abstract:BACKGROUND:Multiple genetic loci are associated with clinical cardiovascular (CV) disease and individual CV risk factors. Individuals with ideal levels of all major CV risk factors have very low risk for CV disease morbidity or mortality. Ideal levels of risk factors can be attained by lifestyle modifications; however,...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.ahj.2015.12.022

    authors: Allen NB,Lloyd-Jones D,Hwang SJ,Rasmussen-Torvik L,Fornage M,Morrison AC,Baldridge AS,Boerwinkle E,Levy D,Cupples LA,Fox CS,Thanassoulis G,Dufresne L,Daviglus M,Johnson AD,Reis J,Rotter J,Palmas W,Allison M,Pankow J

    更新日期:2016-05-01 00:00:00

  • Percutaneous coronary mid-infra-red laser angioplasty.

    abstract::A pilot study was performed to determine the safety and efficacy of coronary pulsed mid-infra-red laser angioplasty. The laser was coupled with a novel 2.0 mm multifiber catheter consisting of 37 optical fibers of 150 microns each arranged concentrically around a 0.018-inch central lumen and a soft leading tapered dis...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(91)91015-f

    authors: Geschwind HJ,Dubois-Rande JL,Zelinsky R,Morelle JF,Boussignac G

    更新日期:1991-08-01 00:00:00

  • Gender differences in dehydration-induced mitral valve prolapse.

    abstract::Mitral valve prolapse (MVP) is a common cardiac valve abnormality that affects women more frequently than men. We have previously shown that mild dehydration induces echocardiographic signs of MVP in approximately 50% of healthy asthenic women with previously normal cardiac findings. The present study was designed to ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(95)90047-0

    authors: Aufderheide S,Lax D,Goldberg SJ

    更新日期:1995-01-01 00:00:00

  • Return to the workforce following infective endocarditis-A nationwide cohort study.

    abstract:BACKGROUND:The ability to return to work after infective endocarditis (IE) holds important socioeconomic consequences for both patients and society, yet data on this issue are sparse. We examined return to the workforce and associated factors in IE patients of working age. METHODS:Using Danish nationwide registries, w...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2017.09.009

    authors: Butt JH,Kragholm K,Dalager-Pedersen M,Rørth R,Kristensen SL,Chaudry MS,Valeur N,Østergaard L,Torp-Pedersen C,Gislason GH,Køber L,Fosbøl EL

    更新日期:2018-01-01 00:00:00

  • Surgical treatment of anomalous left coronary artery from pulmonary artery: follow-up in teenagers and adults.

    abstract::To determine which method of surgical therapy might be optimal for patients with anomalous left coronary artery from the pulmonary artery (ALCAPA), a follow-up study was performed. Twenty-nine teenagers and adults who had ALCAPA diagnosed during life at age 13 years or older were identified mainly by literature search...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(79)90248-5

    authors: Wilson CL,Dlabal PW,McGuire SA

    更新日期:1979-10-01 00:00:00

  • Uniform platelet activation exists before coronary stent implantation despite aspirin therapy.

    abstract:BACKGROUND:Platelets play an important role in the natural history of coronary artery disease. Enhanced platelet aggregation and receptor expression unquestionably occur after coronary stent implantation; however, the functional characteristics of platelets before stenting have not been fully elucidated. METHODS:Plate...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2001.116478

    authors: Serebruany VL,Cummings CC,Malinin AI,Steinhubl SR,Gurbel PA

    更新日期:2001-10-01 00:00:00

  • Influence of intrinsic limb vasodilator capacity on exercise tolerance in patients with recent myocardial infarction.

    abstract::To investigate the influence of intrinsic limb vasodilator capacity on exercise performance, limb reactive hyperemic flows and their relations to exercise capacity during upright bicycle exercise were examined in 52 patients with recent myocardial infarction. Reactive hyperemic flow was measured in the forearm and the...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(96)90243-4

    authors: Hattori T,Sumimoto T,Yuasa F,Kaida M,Jikuhara T,Hikosaka M,Sugiura T,Iwasaka T

    更新日期:1996-09-01 00:00:00

  • Is there an association between aspirin dosing and cardiac and bleeding events after treatment of acute coronary syndrome? A systematic review of the literature.

    abstract:BACKGROUND:Current acetylsalicylic acid (ASA) dosing algorithms for the prevention of secondary thrombotic events in acute coronary syndrome (ACS) patients are inconsistent and lack sufficient data support. METHODS:We performed a systematic review of the literature for studies that assessed clinical outcomes in patien...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ahj.2012.04.001

    authors: Berger JS,Sallum RH,Katona B,Maya J,Ranganathan G,Xu Y,Mwamburi M

    更新日期:2012-08-01 00:00:00

  • Reduction of neointimal hyperplasia after coronary stenting by pioglitazone in nondiabetic patients with metabolic syndrome.

    abstract:BACKGROUND:This study investigates whether pioglitazone reduces neointimal hyperplasia after coronary stenting in nondiabetic patients with metabolic syndrome (MS) using intravascular ultrasound (IVUS). Pioglitazone, a novel insulin-sensitizing thiazolidinedione, has been shown to reduce neointimal hyperplasia after co...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2007.02.022

    authors: Katayama T,Ueba H,Tsuboi K,Kubo N,Yasu T,Kuroki M,Saito M,Momomura S,Kawakami M

    更新日期:2007-05-01 00:00:00

  • Ten-year clinical follow-up after sirolimus-eluting stent implantation.

    abstract:BACKGROUND:Little is known on the "very" long-term incidence of major adverse cardiac events (MACE), target-lesion revascularization (TLR), target-vessel revascularization and stent thrombosis after sirolimus-eluting stent (SES) implantation. We present the first study to provide a 10-year clinical follow-up in an unse...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2013.12.013

    authors: Palhais N,Arroyo D,Lehmann S,Togni M,Kaufmann U,Puricel SG,Stauffer JC,Goy JJ,Cook S

    更新日期:2014-06-01 00:00:00

  • Supported angioplasty with synchronized retroperfusion in high-risk patients with left main trunk or near left main trunk obstruction.

    abstract::To test the feasibility of synchronized retroperfusion (SRP) as a support device of percutaneous transluminal coronary angioplasty (PTCA) for high-risk patients, 10 patients with left main trunk or near left main trunk obstruction underwent PTCA with SRP. An 8.5F retroperfusion catheter was inserted from the antecubit...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(93)90004-s

    authors: Nanto S,Nishida K,Hirayama A,Mishima M,Komamura K,Masai M,Sakakibara T,Kodama K

    更新日期:1993-02-01 00:00:00

  • Chlamydia pneumoniae infection and atherosclerotic coronary disease.

    abstract:BACKGROUND:Previous works have suggested an association between Chlamydia pneumoniae infection and coronary heart disease. We evaluated the prevalence of C. pneumoniae infection in patients with acute myocardial infarction (AMI) and coronary heart disease (CHD). METHODS AND RESULTS:Ninety-eight patients with AMI, 80 p...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(99)70371-6

    authors: Sessa R,Di Pietro M,Santino I,del Piano M,Varveri A,Dagianti A,Penco M

    更新日期:1999-06-01 00:00:00