Effects of dexamethasone elution on tissue reaction around stimulating electrodes of endocardial pacing leads in dogs.

abstract：BACKGROUND:Acute heart failure (AHF) remains a major public health burden with a high prevalence and poor prognosis. Relaxin is a naturally occurring peptide hormone that increases cardiac output, arterial compliance, and renal blood flow during pregnancy. The RELAX-AHF-1 study will evaluate the effect of RLX030 (recom...

journal_title：American heart journal

authors： Ponikowski P,Metra M,Teerlink JR,Unemori E,Felker GM,Voors AA,Filippatos G,Greenberg B,Teichman SL,Severin T,Mueller-Velten G,Cotter G,Davison BA

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Automated implantable cardioverter-defibrillators (ICDs) have become standard therapy for patients at high risk for sudden cardiac death. Linked data allow examination of trends in use and long-term survival after ICD implantation in an adult population. METHODS:Linked state-wide person-based data on hospit...

journal_title：American heart journal

authors： Bradshaw PJ,Stobie P,Briffa T,Hobbs MS

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:This study was designed to investigate the efficacy of alteplase double-bolus dosing compared with the front-loaded 90-minute infusion regimen in patients with acute myocardial infarction. Recent pilot studies have suggested that bolus dosing may provide improved efficacy in establishing early, complete, and...

journal_title：American heart journal

authors： Bleich SD,Adgey AA,McMechan SR,Love TW

更新日期：1998-10-01 00:00:00

abstract：:The Institute of Medicine report on the frequency and consequences of medical errors in clinical practice has stimulated physicians to evaluate current practice and means of improving medical care. In the treatment of patients with acute myocardial infarction, previous studies have found that dosing of fibrinolytic th...

journal_title：American heart journal

authors： Cannon CP

更新日期：2000-12-01 00:00:00

abstract：:The presence of a large ventricular septal defect (VSD) may affect the surgical treatment of congenital heart defects. VSD size and shape by two-dimensional echocardiography (2DE) and at autopsy were compared in 18 patients, average age 6 months, who had 2DE studies shortly prior to death. Six had isolated VSD and the...

journal_title：American heart journal

authors： Sharif DS,Huhta JC,Marantz P,Hawkins HK,Yoon GY

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVES:The objective of this study is to assess trends in evidence-based therapy use and short- and long-term mortality over time among older patients with non-ST-segment elevation myocardial infarction (NSTEMI). BACKGROUND:With the prevalence of national quality improvement efforts, the use of evidence-based ther...

journal_title：American heart journal

authors： Chin CT,Wang TY,Chen AY,Mathews R,Alexander KP,Roe MT,Peterson ED

更新日期：2014-01-01 00:00:00

abstract：:To investigate the sequence of changes in regional myocardial perfusion which precedes stress-induced angina, we measured great cardiac vein flow (GCVF), draining the anterior left ventricle, during incremental atrial pacing in 10 patients with normal anterior perfusion (group I) and in 11 patients with greater than o...

journal_title：American heart journal

authors： Wilson JR,Martin JL,Untereker WJ,Laskey W,Hirshfeld JW

更新日期：1984-02-01 00:00:00

abstract：:Even though congestive heart failure is extremely common, the mechanisms responsible for the clinical manifestations remain a puzzle. The central and autonomic (sympathetic) nervous systems are responsible for a large part of the clinical manifestations. The role of the nervous system in CHF is discussed briefly. It i...

journal_title：American heart journal

authors： Burch GE

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Aortopulmonary collaterals (APCs) are frequently observed before and after the Fontan procedure. However, the mechanism of the development of APCs is unknown. We hypothesized that one or several antiangiogenic and/or angiogenic growth factors might play a role in the development of APCs. METHODS:Eighty-five...

journal_title：American heart journal

authors： Mori Y,Shoji M,Nakanishi T,Fujii T,Nakazawa M

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Contemporary use of dual antiplatelet therapy and consistency with guideline recommendations in acute coronary syndrome patients undergoing percutaneous coronary intervention (PCI) have not been well characterized. METHODS:The COAPT was a prospective, observational, multicenter, longitudinal study of patien...

journal_title：American heart journal

authors： Déry JP,Mehta SR,Fisher HN,Zhang X,Zhu YE,Welsh RC,Lavi S,Cieza T,Henderson MA,Lutchmedial S,Siega AJ,Cheema AN,Wong BY,Kokis A,Dehghani P,Goodman SG,Canadian Observational AntiPlatelet sTudy (COAPT) Investigators.

更新日期：2016-11-01 00:00:00

abstract：:A 17-year-old man with staphylococcal endocarditis of the mitral valve developed an infective aneurysm of the posterior left ventricular wall. Echocardiography revealed an echo-free space posterior to the posterior left ventricular wall. This echo-free space undoubtedly represented the aneurysmal sac, because it could...

journal_title：American heart journal

authors： Saksena FB,Kramer NE,Towne WD,Khan M,Gamble R,Cruz JB,Gill S

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:Peripheral endothelial dysfunction (ED) quantified by the determination of flow-mediated dilation (FMD%) of the brachial artery with the use of high-resolution ultrasound is an early marker of atherosclerosis. Although a positive correlation with coronary artery disease (CAD) has been reported, the unanswere...

journal_title：American heart journal

authors： Schroeder S,Enderle MD,Ossen R,Meisner C,Baumbach A,Pfohl M,Herdeg C,Oberhoff M,Haering HU,Karsch KR

更新日期：1999-10-01 00:00:00

abstract：:The rate and form of creatine kinase-MB (CK-MB) enzyme release following reflow to ischemic myocardium has not been specifically examined in man. In this investigation, we examined the combined CK-MB time-activity curves during acute transmural myocardial infarction (AMI) in a group of patients receiving conventional ...

journal_title：American heart journal

authors： Shell W,Mickle DK,Swan HJ

更新日期：1983-10-01 00:00:00

abstract：:Atrial fibrillation is a common disease of the elderly, conferring considerable morbidity and mortality related to cardiovascular effects and thromboembolic risks. Anticoagulation, antiarrhythmic medications, and rate control are the cornerstone of contemporary management, whereas ablation and evolving surgical techni...

journal_title：American heart journal

authors： Hui DS,Morley JE,Mikolajczak PC,Lee R

更新日期：2015-04-01 00:00:00

abstract：:Meta-analyses of major outcome trials have demonstrated that the benefits of antihypertensive treatment for reduction of the incidence of stroke are entirely consistent with the benefits predicted from epidemiologic data; however, there remains a shortfall in the expected reduction of the incidence of coronary heart d...

journal_title：American heart journal

authors： Meredith PA

更新日期：1996-07-01 00:00:00

abstract：:The purpose of this study was to determine the effect of age on the in-hospital mortality of all 30,972 patients undergoing coronary artery bypass graft (CABG) surgery in New York in 1991 and 1992. Mortality rates were relatively low for patients 40-49, 50-59, and 60-64, 65-69, and 70-74 years old (1.10%, 1.65%, 2.17%...

journal_title：American heart journal

authors： Hannan EL,Burke J

更新日期：1994-12-01 00:00:00

abstract：:T-lymphocyte levels may adversely affect the clinical course and outcome of patients with acute myocardial infarction (AMI). To characterize the T-lymphocyte profile during AMI and to explore whether these cells play a detrimental role in the extent of myocardial insult, levels of T-lymphocyte subpopulations, free sol...

journal_title：American heart journal

authors： Blum A,Sclarovsky S,Rehavia E,Shohat B

更新日期：1994-05-01 00:00:00

abstract：:We evaluated the long-term angiographic outcome of balloon angioplasty by comparing original and follow-up target coronary narrowing. Rather than using restenosis to determine outcome, as in most angioplasty studies, we took an unusual approach and analyzed outcome in terms that are commonly used in progression and re...

journal_title：American heart journal

authors： Rozenman Y,Gilon D,Sapoznikov D,Lotan C,Mosseri M,Hasin Y,Gotsman MS

更新日期：1997-05-01 00:00:00

abstract：:Incidence of myonecrosis in patients undergoing rotational atherectomy was evaluated by preprocedural statin use. The incidence of any myonecrosis (24.1% vs 52.3%, P < .001) or significant myonecrosis (7.5% vs 21.8%, P < .001) was significantly lower among patients pretreated with statins. This difference remained sig...

journal_title：American heart journal

authors： Gurm HS,Breitbart Y,Vivekanathan D,Yen MH,Fathi R,Ziada KM,Whitlow PL,Ellis SG

更新日期：2006-05-01 00:00:00

abstract：:To test the hypothesis that elevated plasma levels of natriuretic peptides may serve to identify patients with left ventricular (LV) dysfunction, we assessed the predictive diagnostic value of natriuretic peptide levels, in addition to clinical and electro-cardiographic risk factors, as noninvasive indicators of cardi...

journal_title：American heart journal

authors： Muders F,Kromer EP,Griese DP,Pfeifer M,Hense HW,Riegger GA,Elsner D

更新日期：1997-09-01 00:00:00

abstract：:There has been skepticism since the early days of open heart surgery that good long-term or even short-term results were possible with repair of pure mitral insufficiency. The authors report 145 patients in whom a markedly insufficient mitral valve was repaired 6 months to 17 years previously and another 55 patients i...

journal_title：American heart journal

authors： Kay JH,Zubiate P,Mendez MA,Vanstrom N,Yokoyama T

更新日期：1978-08-01 00:00:00

abstract：:To determine the clinical usefulness of echocardiography in patients with anteroseptal myocardial infarction, echocardiograms were performed within 24 hours of admission on 40 patients with acute transmural anteroseptal myocardial infarction. Twenty-one patients had normal septal motion and septal systolic thickening,...

journal_title：American heart journal

authors： Wiener I,Meller J,Packer M,Herman MV,Teichholz LE

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:High-intensity interval training has been shown to be superior to moderate continuous exercise training in improving exercise capacity and endothelial function in patients with coronary artery disease. The objective of this study was to evaluate this training model on in-stent restenosis following percutaneo...

journal_title：American heart journal

authors： Munk PS,Staal EM,Butt N,Isaksen K,Larsen AI

更新日期：2009-11-01 00:00:00

abstract：:To explore the contribution of reperfusion injury to final infarct size after a short duration of ischemia, closed-chest dogs underwent 40 minutes of proximal left anterior descending artery occlusion followed by 3 days of reperfusion. Animals randomly received intracoronary adenosine (n = 8) at 3.75 mg/min during the...

journal_title：American heart journal

authors： Velasco CE,Turner M,Cobb MA,Virmani R,Forman MB

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Endothelin 1 is a potent endogenous vasoconstrictor neurohormone, and endothelin 1 plasma concentrations predict adverse outcomes in patients with acute heart failure (AHF). Tezosentan, an intravenous endothelin receptor antagonist, improved hemodynamics in patients with AHF; however, its effects on morbidit...

journal_title：American heart journal

authors： Teerlink JR,McMurray JJ,Bourge RC,Cleland JG,Cotter G,Jondeau G,Krum H,Metra M,O'Connor CM,Parker JD,Torre-Amione G,Van Veldhuisen DJ,Frey A,Rainisio M,Kobrin I,VERITAS Investigators.

更新日期：2005-07-01 00:00:00

abstract：:Left ventricular (LV) outflow obstruction may result from retaining the anterior mitral leaflet when a mitral prosthesis is inserted in the mitral anulus. We retrospectively reviewed the echocardiograms (two-dimensional Doppler and Doppler color flow imaging, or transesophageal with color flow imaging) obtained in sev...

journal_title：American heart journal

authors： Waggoner AD,Pérez JE,Barzilai B,Rosenbloom M,Eaton MH,Cox JL

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:In animal models, physical activity (PA) prevents cardiac myocyte cell death. Data for PA mitigating myocyte injury in humans are limited to observational studies. Using a randomized controlled trial design, we sought to determine if introducing moderate PA to previously sedentary older adults could reduce t...

journal_title：American heart journal

authors： deFilippi CR,de Lemos JA,Newman AB,Guralnik JM,Christenson RH,Pahor M,Church T,Espeland M,Krithevsky SB,Stafford R,Seliger SL,LIFE Study Group.

更新日期：2016-09-01 00:00:00

abstract：:The serum chromium in 45 subjects with no clinical evidence of ischemic heart disease was found to be 1.71 parts per billion (ppb) (S.E. +/- 0.14). In 34 patients with a previously documented myocardial infarction, it was 1.84 ppb (S.E. +/- 0.18). The difference was not significant nor was there any difference with ag...

journal_title：American heart journal

authors： Abraham AS,Sonnenblick M,Eni M,Shemesh O,Batt AP

更新日期：1980-05-01 00:00:00

abstract：:Resting measurements of left ventricular systolic function do not reliably predict exercise capacity in patients with cardiac disease. Therefore left ventricular filling shortly after a myocardial infarction was prospectively studied to determine whether it could predict subsequent exercise time. Consecutive patients ...

journal_title：American heart journal

authors： Finkelhor RS,Sun JP,Bahler RC

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Complications of vascular access are one of the most common adverse events after coronary angiography and percutaneous coronary intervention (PCI) and are reported to occur in 1% to 9% of cases. There are conflicting reports of the association of vascular complications with the use of vascular closure device...

journal_title：American heart journal

authors： Arora N,Matheny ME,Sepke C,Resnic FS

更新日期：2007-04-01 00:00:00