当前位置： SCI文献检索 > AMERICAN HEART JOURNAL期刊下所有文献 > Neurohumoral and hemodynamic effects of lower body negative pressure in patients with congestive heart failure.

Neurohumoral and hemodynamic effects of lower body negative pressure in patients with congestive heart failure.

Abstract：

:Baroreflex modulation of forearm vascular resistance (FVR) has been reported to be abnormal in patients with congestive heart failure (CHF). However, the neurohumoral mechanisms for this impairment are not defined. We assessed the responses of arterial pressure, FVR, plasma norepinephrine, and plasma renin activity to lower body negative pressure in 29 patients with compensated CHF (New York Heart Association class III and IV) and in 11 normal age-matched control subjects. Baseline mean arterial pressure (83 +/- 2 vs 84 +/- 2 mm Hg) and mean arterial pressure during LBNP (-10, -20, and -40 mm Hg) were not significantly different in the two groups. Basal FVR (43.7 +/- 4 vs 27 +/- 2 units), plasma norepinephrine (605 +/- 81 vs 155 +/- 8 pg/ml), and plasma renin activity (8.3 +/- 1.7 vs 1.2 +/- 0.2 ng/ml/hr) were significantly (p less than 0.01) higher in patients with CHF. The relative increases in FVR responses during LBNP of -10, -20, and -40 mm Hg (10 +/- 4% vs 70 +/- 12%, 17 +/- 6% vs 106 +/- 21%, and 24 +/- 9% vs 152 +/- 28%) were markedly attenuated in patients with CHF compared to control subjects. Plasma norepinephrine and plasma renin activity responses during LBNP were also attenuated in patients with heart failure. Our results suggest that baroreflex control of FVR and plasma norepinephrine and plasma renin activity is impaired in CHF because of the inability of the cardiopulmonary baroreceptors to alter sympathetic outflow.

journal_name

Am Heart J

journal_title

American heart journal

authors

Mohanty PK,Arrowood JA,Ellenbogen KA,Thames MD

doi

10.1016/0002-8703(89)90075-6

subject

Has Abstract

pub_date

1989-07-01 00:00:00

pages

78-85

issue

1

eissn

0002-8703

issn

1097-6744

pii

0002-8703(89)90075-6

journal_volume

118

pub_type

杂志文章

相关文献

AMERICAN HEART JOURNAL文献大全
  • Imaging and diagnostic testing: diastolic dysfunction after coronary artery bypass grafting: a frequent finding of clinical significance not influenced by intravenous calcium.

    abstract：BACKGROUND:Diastolic dysfunction is common immediately after coronary artery bypass surgery (CABG). The duration of this phenomenon is unknown. Intravenous calcium is frequently administered during separation from cardiopulmonary bypass (CPB). We sought to determine whether intravenous calcium influences perioperative ...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/S0002-8703(02)94786-1

    authors： Ekery DL,Davidoff R,Orlandi QG,Apstein CS,Hesselvik JF,Shemin RJ,Shapira OM

    更新日期：2003-05-01 00:00:00

  • Two-dimensional echocardiography and color Doppler imaging in patients with systolic-diastolic murmurs.

    abstract：:Characteristics of color-coded Doppler imaging combined with two-dimensional and M-mode echocardiography in six patients with systolic-diastolic murmurs are reported. PDA, congenital absence of pulmonary valve leaflets, ventricular septal defect and aortic regurgitation, two ruptured aneurysms of sinus of Valsalva, an...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(87)90551-5

    authors： Vargas-Barron J,Attie F,Skronme D,Sanchez-Ugarte T,Keirns C,Santana-Gonzalez A

    更新日期：1987-12-01 00:00:00

  • Reciprocal rhythm in patients with normal electrocardiogram: Evidence for dual conduction pathways.

    abstract：:The present study refers to six patients in whom an A-V reciprocal rhythm could be documented; in four cases it took the form of sustained tachycardia. None of the patients showed any ECG feature of ventricular pre-excitation (PR interval of more than 0.12 sec. and normal QRS configuration). The extrastimulus method s...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(76)80427-9

    authors： Touboul P,Huerta F,Porte J,Delahaye JP

    更新日期：1976-01-01 00:00:00

  • Changes occurring in the postinfarction ECG in relation to age, sex, and previous myocardial infarction.

    abstract：:Minnesota codes (MC), expressing Q-QS, ST segment, and T wave abnormalities in ECGs taken during the acute event and at a 1-year follow-up were studied in 256 survivors of myocardial infarction (MI). On the 1-year ECGs large Q waves (MC 1.1) were more common in patients with a history of previous MI than in those with...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(86)90141-9

    authors： Rissanen V,Raunio H,Halinen MO,Rehnberg S

    更新日期：1986-02-01 00:00:00

  • Enhancement of pulsed-dye laser ablation of arterial tissues with blood medium: effects of laser-induced shock waves.

    abstract：:The influence of blood medium on tissue ablation by a pulsed dye laser and its selectivity for atheroma were investigated. The role of shock waves on tissue ablation was also evaluated. Normal and atherosclerotic human aortas were irradiated by a 480 nm pulsed dye laser activated at 5 Hz. The laser was coupled with a ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(91)90529-q

    authors： Tomaru T,Geschwind HJ,Lange F,Boussignac G

    更新日期：1991-09-01 00:00:00

  • Restenosis revisited: insights provided by quantitative coronary angiography.

    abstract：:In this editorial, the problem of restenosis after coronary balloon angioplasty and other transluminal interventions is reviewed from the perspective of quantitative coronary angiography. The review is largely based on the experience of the Thoraxcentre in the application of quantitative angiography to the study of re...

    journal_title：American heart journal

    pub_type： 社论

    doi：10.1016/0002-8703(93)90689-7

    authors： Serruys PW,Foley DP,Kirkeeide RL,King SB 3rd

    更新日期：1993-11-01 00:00:00

  • Design and rationale of the TRI-stent adjudication study (TRIAS) program.

    abstract：BACKGROUND:In the treatment of coronary artery disease, a "pro-healing" approach for prevention of in-stent restenosis and late stent thrombosis is intuitively favored over the use of cytotoxic or cytostatic drugs released from a drug-eluting stent (DES). Promoting accelerated endothelial coverage of the stent surface,...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2009.07.022

    authors： Klomp M,Beijk MA,Verouden NJ,Tijssen JG,de Winter RJ,TRIAS Investigators.

    更新日期：2009-10-01 00:00:00

  • Evaluation of coronary artery calcium screening strategies focused on risk categories: the Dallas Heart Study.

    abstract：BACKGROUND:A strategy using coronary artery calcium (CAC) screening to refine coronary heart disease risk assessment in moderately high risk (MHR) subjects (10-year risk 10%-20%) has been suggested. The potential impact of this strategy is unknown. METHODS:Coronary artery calcium screening strategies focused on MHR su...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2009.03.018

    authors： Patel MJ,de Lemos JA,McGuire DK,See R,Lindsey JB,Murphy SA,Grundy SM,Khera A

    更新日期：2009-06-01 00:00:00

  • The role of the emergency department in acute heart failure clinical trials--enriching patient identification and enrollment.

    abstract：:Nearly 800,000 of the 1 million patients hospitalized with acute heart failure (AHF) every year are initially treated by emergency physicians. Signs and symptoms are typically most severe at initial presentation, but with timely diagnostic and therapeutic management, rapid improvement can be achieved. As a direct resu...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/j.ahj.2013.03.009

    authors： Collins SP,Levy PD,Pang PS,Gheorghiade M

    更新日期：2013-06-01 00:00:00

  • Baseline characteristics, adenosine diphosphate receptor inhibitor treatment patterns, and in-hospital outcomes of myocardial infarction patients undergoing percutaneous coronary intervention in the prospective Canadian Observational AntiPlatelet sTudy (C

    abstract：BACKGROUND:Contemporary use of dual antiplatelet therapy and consistency with guideline recommendations in acute coronary syndrome patients undergoing percutaneous coronary intervention (PCI) have not been well characterized. METHODS:The COAPT was a prospective, observational, multicenter, longitudinal study of patien...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2016.07.014

    authors： Déry JP,Mehta SR,Fisher HN,Zhang X,Zhu YE,Welsh RC,Lavi S,Cieza T,Henderson MA,Lutchmedial S,Siega AJ,Cheema AN,Wong BY,Kokis A,Dehghani P,Goodman SG,Canadian Observational AntiPlatelet sTudy (COAPT) Investigators.

    更新日期：2016-11-01 00:00:00

  • Influence of gradually increased slow balloon inflation on restenosis after coronary angioplasty.

    abstract：BACKGROUND:Balloon inflation during coronary angioplasty results in shear stress-induced vessel wall injury with development of restenosis. This randomized trial compared the impact of two different balloon inflation strategies (slow versus fast) on restenosis after coronary angioplasty. METHODS:Two hundred seven pati...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0002-8703(98)70290-x

    authors： Miketic S,Carlsson J,Tebbe U

    更新日期：1998-04-01 00:00:00

  • The role of transesophageal echocardiography in cardiac donor screening.

    abstract：:Transthoracic echocardiography has played a useful role in the screening of cardiac transplant donors. However, transthoracic echocardiograms may be suboptimal in many patients on ventilators. The role of transesophageal echocardiography in cardiac donor screening is unknown. Therefore we compared the potential benefi...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(93)90758-2

    authors： Stoddard MF,Longaker RA

    更新日期：1993-06-01 00:00:00

  • No variants in the cardiac actin gene in Finnish patients with dilated or hypertrophic cardiomyopathy.

    abstract：BACKGROUND:Dilated and hypertrophic cardiomyopathies are primary myocardial diseases that cause considerable morbidity and mortality. Although these cardiomyopathies are clinically heterogeneous, genetic factors play an important role in their etiology and pathogenesis. The defects in the cardiac actin (ACTC) gene can ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1067/mhj.2002.122514

    authors： Kärkkäinen S,Peuhkurinen K,Jääskeläinen P,Miettinen R,Kärkkäinen P,Kuusisto J,Laakso M

    更新日期：2002-06-01 00:00:00

  • A randomized controlled trial of low-dose hormone therapy on myocardial ischemia in postmenopausal women with no obstructive coronary artery disease: results from the National Institutes of Health/National Heart, Lung, and Blood Institute-sponsored Women'

    abstract：BACKGROUND:Compared with men, women have more evidence of myocardial ischemia with no obstructive coronary artery disease. Although low endogenous estrogen levels are associated with endothelial dysfunction, the role of low-dose hormone therapy has not been fully evaluated. We postulate that a 12-week duration of low-d...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2010.03.024

    authors： Merz CN,Olson MB,McClure C,Yang YC,Symons J,Sopko G,Kelsey SF,Handberg E,Johnson BD,Cooper-DeHoff RM,Sharaf B,Rogers WJ,Pepine CJ

    更新日期：2010-06-01 00:00:00

  • Unsuccessful reperfusion in patients with ST-segment elevation myocardial infarction treated by primary angioplasty.

    abstract：BACKGROUND:Several studies have shown that patency of the epicardial vessel does not guarantee optimal myocardial perfusion in patients undergoing primary angioplasty for ST-segment elevation myocardial infarction (STEMI). The aim of the current study was to identify clinical and angiographic correlates of unsuccessful...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2004.10.044

    authors： De Luca G,van 't Hof AW,Ottervanger JP,Hoorntje JC,Gosselink AT,Dambrink JH,Zijlstra F,de Boer MJ,Suryapranata H

    更新日期：2005-09-01 00:00:00

  • Race and ethnicity influences on cardiovascular and renal events in patients with diabetes mellitus.

    abstract：BACKGROUND:The incidence of end-stage renal disease (ESRD) has been consistently shown to be higher among blacks and Hispanics compared to whites with unmeasured risk factors and access to care as suggested explanations. In a high-risk cohort with frequent protocol-directed follow-up, we evaluated the influence of race...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2015.05.008

    authors： Lewis EF,Claggett B,Parfrey PS,Burdmann EA,McMurray JJ,Solomon SD,Levey AS,Ivanovich P,Eckardt KU,Kewalramani R,Toto R,Pfeffer MA

    更新日期：2015-08-01 00:00:00

  • Long-term outcome after heart transplantation for peripartum cardiomyopathy.

    abstract：:To elucidate the long-term outcome and frequency of complications after heart transplantation for peripartum cardiomyopathy (PPCM), we compared the courses of eight consecutive patients undergoing transplantation for PPCM with those of nine female age-matched control subjects undergoing transplantation for idiopathic ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(94)90051-5

    authors： Rickenbacher PR,Rizeq MN,Hunt SA,Billingham ME,Fowler MB

    更新日期：1994-05-01 00:00:00

  • Atrial septal aneurysms in infants and children.

    abstract：:Interatrial septal aneurysm (IASA) has been detected with increasing frequency since the advent of two-dimensional echocardiography (2DE). In this study, we investigated the prevalence, characteristics, and predisposing factors in IASA formation in 724 infants, children, and adolescents undergoing 2DE. Among this grou...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(87)90927-6

    authors： Wolf WJ,Casta A,Sapire DW

    更新日期：1987-05-01 00:00:00

  • Fondaparinux versus Enoxaparin in non-ST-elevation acute coronary syndromes: short-term cost and long-term cost-effectiveness using data from the Fifth Organization to Assess Strategies in Acute Ischemic Syndromes Investigators (OASIS-5) trial.

    abstract：BACKGROUND:The study aimed to compare the short-term costs and long-term cost-effectiveness of 2 antithrombotics, fondaparinux and enoxaparin, for non-ST-elevation acute coronary syndrome in the United States. METHODS:It was based on a large randomized trial of 20,078 patients Fifth Organization to Assess Strategies i...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2009.02.017

    authors： Sculpher MJ,Lozano-Ortega G,Sambrook J,Palmer S,Ormanidhi O,Bakhai A,Flather M,Steg PG,Mehta SR,Weintraub W

    更新日期：2009-05-01 00:00:00

  • Epidemiology of angina pectoris: role of natural language processing of the medical record.

    abstract：BACKGROUND:The diagnosis of angina is challenging because it relies on symptom descriptions. Natural language processing (NLP) of the electronic medical record (EMR) can provide access to such information contained in free text that may not be fully captured by conventional diagnostic coding. OBJECTIVE:To test the hyp...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2006.12.022

    authors： Pakhomov SS,Hemingway H,Weston SA,Jacobsen SJ,Rodeheffer R,Roger VL

    更新日期：2007-04-01 00:00:00

  • Saphenous vein graft failure and clinical outcomes: toward a surrogate end point in patients following coronary artery bypass surgery?

    abstract：:Saphenous vein graft (SVG) failure is a common finding in patients following coronary artery bypass graft (CABG) surgery. In the literature SVG failure rates have been reported from 25 to over 50% within 10 years. Although common, it remains unclear to what extent SVG failure affects clinical outcome, due to differenc...

    journal_title：American heart journal

    pub_type： 社论

    doi：10.1016/j.ahj.2013.01.019

    authors： Harskamp RE,Williams JB,Hill RC,de Winter RJ,Alexander JH,Lopes RD

    更新日期：2013-05-01 00:00:00

  • Peripheral hemodynamic effects of captopril in patients with congestive heart failure.

    abstract：:In 14 patients with severe congestive heart failure, the effects of captopril on the forearm circulation were evaluated with strain gauge plethysmography. Changes in plasma renin activity, angiotensin II, norepinephrine, epinephrine, bradykinin, prostaglandin E2, and 6-keto-prostaglandin F1 alpha concentrations were a...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(89)90662-5

    authors： Nishimura H,Kubo S,Ueyama M,Kubota J,Kawamura K

    更新日期：1989-01-01 00:00:00

  • Optimal features of a new beta-blocker.

    abstract：:Therapeutics involves the careful balance between treatment disadvantages and advantages--the so-called risk-benefit ratio. Even after 20 years beta-blockers must be selected carefully to suit the patient's needs. This review examines several problems associated with beta-blockade. Generally, beta1-cardioselectivity i...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/0002-8703(88)90130-5

    authors： Reid JL

    更新日期：1988-11-01 00:00:00

  • The effects of atrial pacing on the signal-averaged electrocardiogram in patients with coronary artery disease.

    abstract：:The effects of atrial pacing on the signal-averaged electrocardiogram were studied in 14 patients with remote myocardial infarction and a history of cardiac arrest or sustained ventricular tachycardia (group I) and in 13 patients with coronary artery disease and no history of sustained ventricular tachyarrhythmia (gro...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(05)80077-8

    authors： Greenspon AJ,Volosin K

    更新日期：1990-01-01 00:00:00

  • Predicting significant coronary artery disease in patients with left ventricular dysfunction.

    abstract：BACKGROUND:Because coronary artery disease (CAD) is a prevalent comorbidity in patients with low ejection function (EF), a number of patients with heart failure undergo diagnostic cardiac catheterization. The objective of this study was to develop a model to assist clinicians in determining the likelihood of CAD before...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2005.12.001

    authors： Whellan DJ,Tuttle RH,Velazquez EJ,Shaw LK,Jollis JG,Ellis W,O'Connor CM,Califf RM,Borges-Neto S

    更新日期：2006-08-01 00:00:00

  • Cardiovascular manifestations of Lyme disease.

    abstract：:Although the cardiac manifestations of Lyme disease may be diverse, in general they are treatable with currently available therapies. A high index of suspicion is required to make a diagnosis, especially for patients who may lack a suggestive history of tick exposure or residence in an endemic region. Lyme disease-rel...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/0002-8703(91)90589-a

    authors： Cox J,Krajden M

    更新日期：1991-11-01 00:00:00

  • Short-term infarct vessel patency with aspirin and dipyridamole started 24 to 36 hours after intravenous streptokinase.

    abstract：:The duration of intravenous heparin therapy required to maintain patency of the infarct-related artery after intravenous streptokinase is uncertain. Twenty-eight patients were prospectively treated with 1.5 million units of intravenous streptokinase within 4 hours of onset of chest pain. Intravenous heparin was begun ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(88)90870-8

    authors： Hays LJ,Beller GA,Moore CA,Burwell LR,Craddock GB,Gascho JA,Smucker ML,Tedesco C,Nygaard TW

    更新日期：1988-04-01 00:00:00

  • Erythropoietin as a treatment of anemia in heart failure: systematic review of randomized trials.

    abstract：BACKGROUND:Anemia in heart failure is both common and associated with worse symptoms and increased mortality. Several small randomized controlled trials (RCTs) have assessed erythropoiesis-stimulating agents (ESAs), but definitive evaluation and clinical guidance are required. We sought to systematically review the eff...

    journal_title：American heart journal

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.ahj.2011.02.013

    authors： Kotecha D,Ngo K,Walters JA,Manzano L,Palazzuoli A,Flather MD

    更新日期：2011-05-01 00:00:00

  • Effect of rosuvastatin on C-reactive protein and progression of aortic stenosis.

    abstract：BACKGROUND:Elevated C-reactive protein (CRP) is a common finding in patients with aortic stenosis (AS) and may be associated with rapid AS progression and worse outcome. The purpose of the study was to examine the role of high-sensitivity CRP and its interaction with rosuvastatin on the progression of AS. METHODS:We m...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2011.03.016

    authors： Chan KL,Dumesnil JG,Tam J,Ni A,Teo K

    更新日期：2011-06-01 00:00:00

  • PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: summary of the literature and implications for genetic testing.

    abstract：BACKGROUND:hypertrophic cardiomyopathy (HCM) is a major cause of sudden death in young athletes and one of the most common inherited cardiovascular diseases, affecting 1 in 500 individuals. Often viewed as a disease of the cardiac sarcomere, mutations in genes encoding myofilament proteins are associated with disease p...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2010.08.001

    authors： Landstrom AP,Adekola BA,Bos JM,Ommen SR,Ackerman MJ

    更新日期：2011-01-01 00:00:00