当前位置： SCI文献检索 > AMERICAN HEART JOURNAL期刊下所有文献 > Predicting significant coronary artery disease in patients with left ventricular dysfunction.

Predicting significant coronary artery disease in patients with left ventricular dysfunction.

Abstract：

BACKGROUND:Because coronary artery disease (CAD) is a prevalent comorbidity in patients with low ejection function (EF), a number of patients with heart failure undergo diagnostic cardiac catheterization. The objective of this study was to develop a model to assist clinicians in determining the likelihood of CAD before cardiac catheterization. METHODS:This study was a retrospective analysis using the Duke Databank for Cardiovascular Disease. From the databank, 2054 patients who underwent cardiac catheterization between 1992 and 2002 that was preceded by echocardiography with an EF of < 45% were identified. The patients' median age was 63 years, and the median EF was 30%. Patients were considered to have significant CAD if any major epicardial vessel had > or = 75% stenosis. A multivariable model of CAD was generated using stepwise logistic regression. We included demographic, clinical, electrocardiographic, and echocardiographic parameters, including segmental wall motion abnormality. RESULTS:Of the patients who met the criteria, 1184 (58%) had significant CAD and 870 (42%) did not. Significant predictors of CAD, in the order of their ability to predict significant CAD, included history of myocardial infarction, age, diabetes mellitus, Q wave on electrocardiogram, male sex, and segmental wall motion abnormality (all P < .0001). The area under the receiver operating characteristic curve was 0.865. CONCLUSIONS:By using baseline demographic and clinical characteristics, we developed a highly discriminatory diagnostic model for predicting CAD in patients with heart failure. Given the high prevalence of patients without CAD in this cohort, accurate baseline assessment of patients with left ventricular dysfunction for CAD might avoid unnecessary invasive procedures.

journal_name

Am Heart J

journal_title

American heart journal

authors

Whellan DJ,Tuttle RH,Velazquez EJ,Shaw LK,Jollis JG,Ellis W,O'Connor CM,Califf RM,Borges-Neto S

doi

10.1016/j.ahj.2005.12.001

subject

Has Abstract

pub_date

2006-08-01 00:00:00

pages

340-7

issue

2

eissn

0002-8703

issn

1097-6744

pii

S0002-8703(05)01051-3

journal_volume

152

pub_type

杂志文章

相关文献

AMERICAN HEART JOURNAL文献大全
  • Effects of exercise training on left ventricular volumes and function in patients with nonischemic cardiomyopathy: application of magnetic resonance myocardial tagging.

    abstract：BACKGROUND:Exercise training is now an accepted component of the therapeutic regimen in patients with heart failure and underlying ischemia, but few data are available on the effects of training in patients with nonischemic dilated cardiomyopathy. METHODS:Twenty-four patients (mean age 55 +/- 9 years, mean ejection fr...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1067/mhj.2002.124401

    authors： Myers J,Wagner D,Schertler T,Beer M,Luchinger R,Klein M,Rickli H,Muller P,Mayer K,Schwitter J,Dubach P

    更新日期：2002-10-01 00:00:00

  • Natural history of subarterial infundibular ventricular septal defect.

    abstract：:Development of aortic valvular deformities was studied retrospectively in 395 inpatients with subarterial infundibular ventricular septal defect (siVSD). Aortic valvular deformities included prolapse into siVSD without aortic regurgitation (77 patients), prolapse and aortic regurgitation (95 patients), and aneurysm of...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(84)90759-2

    authors： Momma K,Toyama K,Takao A,Ando M,Nakazawa M,Hirosawa K,Imai Y

    更新日期：1984-11-01 00:00:00

  • Systemic, noncerebral, arterial embolism in 21,105 patients with atrial fibrillation randomized to edoxaban or warfarin: results from the Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction

    abstract：BACKGROUND:Atrial fibrillation (AF) is a major risk factor for stroke and systemic embolism. Trials comparing warfarin with non-vitamin K oral anticoagulants (NOACs) have demonstrated that, when compared with warfarin, the NOACs are at least as effective in preventing stroke, although detailed analyses characterizing s...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2015.06.020

    authors： Geller BJ,Giugliano RP,Braunwald E,Murphy SA,Hanyok JJ,Jin J,Mercuri M,Antman EM,Ruff CT

    更新日期：2015-10-01 00:00:00

  • Adjuvant metoprolol improves efficacy of class I antiarrhythmic drugs in patients with inducible sustained monomorphic ventricular tachycardia.

    abstract：:Inducible ventricular tachycardia frequently persists despite solitary class I antiarrhythmic drug therapy. To determine the effect of metoprolol as adjuvant therapy, 19 patients with clinical ventricular tachycardia with baseline inducible sustained monomorphic ventricular tachycardia and persistently inducible ventr...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(92)90270-6

    authors： Brodsky MA,Chough SP,Allen BJ,Capparelli EV,Orlov MV,Caudillo G

    更新日期：1992-09-01 00:00:00

  • The effects of periodontal therapy on vascular endothelial function: a pilot trial.

    abstract：BACKGROUND:Chronic periodontal infection is associated with an increased risk of coronary heart disease. Although the mechanism responsible for the relationship between periodontal disease and cardiovascular events is not fully understood, it is hypothesized that the chronic inflammatory burden of periodontal disease m...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2005.10.002

    authors： Elter JR,Hinderliter AL,Offenbacher S,Beck JD,Caughey M,Brodala N,Madianos PN

    更新日期：2006-01-01 00:00:00

  • Achieving rapid reperfusion with primary percutaneous coronary intervention remains a challenge: insights from American Heart Association's Get With the Guidelines program.

    abstract：BACKGROUND:The speed of reperfusion (door-to-balloon [D2B] time) is a well established performance metric for patients with ST-elevation myocardial infarction. Although preferably D2B times should be

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2008.01.010

    authors： Mehta RH,Bufalino VJ,Pan W,Hernandez AF,Cannon CP,Fonarow GC,Peterson ED,American Heart Association Get With the Guidelines Investigators.

    更新日期：2008-06-01 00:00:00

  • Variant angina pectoris: a clinical and coronary arteriographic spectrum.

    abstract：:The clinical course and coronary arteriographic findings in eight patients with Prinzmetal's variant angina pectoris are reviewed and contrasted to previously reported cases. In six patients with S-T-elevation inferiorly, three had normal coronary arteriograms, one had complete right coronary artery occlusion, one ha...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(75)90501-3

    authors： Donsky MS,Harris MD,Curry GC,Blomqvist CG,Willerson JT,Mullins CB

    更新日期：1975-05-01 00:00:00

  • Optimized duration of clopidogrel therapy following treatment with the Endeavor zotarolimus-eluting stent in real-world clinical practice (OPTIMIZE) trial: rationale and design of a large-scale, randomized, multicenter study.

    abstract：BACKGROUND:Current recommendations for antithrombotic therapy after drug-eluting stent (DES) implantation include prolonged dual antiplatelet therapy (DAPT) with aspirin and clopidogrel ≥12 months. However, the impact of such a regimen for all patients receiving any DES system remains unclear based on scientific eviden...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2012.09.009

    authors： Feres F,Costa RA,Bhatt DL,Leon MB,Botelho RV,King SB 3rd,de Paula JE,Mangione JA,Salvadori D Jr,Gusmão MO,Castello H Jr,Nicolela E Jr,Perin MA,Devito FS,Marin-Neto JA,Abizaid A

    更新日期：2012-12-01 00:00:00

  • Relationship between changes in ST segment elevation and patency of the infarct-related coronary artery in acute myocardial infarction.

    abstract：:Forty-one patients with acute myocardial infarction and ST segment elevation were studied to determine the relationship between early changes in ST segment elevation, time to peak serum creatine kinase (CK), peak serum CK, left ventricular function, and patency of the infarct-related artery. ST segment elevation decre...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(86)90262-0

    authors： Hackworthy RA,Vogel MB,Harris PJ

    更新日期：1986-08-01 00:00:00

  • Spironolactone-induced renal insufficiency and hyperkalemia in patients with heart failure.

    abstract：BACKGROUND:A previous randomized controlled trial evaluating the use of spironolactone in heart failure patients reported a low risk of hyperkalemia (2%) and renal insufficiency (0%). Because treatments for heart failure have changed since the benefits of spironolactone were reported, the prevalence of these complicati...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2004.10.005

    authors： Tamirisa KP,Aaronson KD,Koelling TM

    更新日期：2004-12-01 00:00:00

  • Should we cross the valve: the risk of retrograde catheterization of the left ventricle in patients with aortic stenosis.

    abstract：CLINICAL SCENARIO:A 67-year-old man is referred to your cardiology clinic complaining of worsening angina and dyspnea on exertion. Physical examination reveals a harsh grade IV/VI late-peaking crescendo-decresendo systolic murmur, loudest at the upper sternal border. The aortic closure sound is diminished. Echocardiogr...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2004.05.031

    authors： Meine TJ,Harrison JK

    更新日期：2004-07-01 00:00:00

  • Diabetic angiopathy--its lessons in vascular physiology.

    abstract：:Progress in our understanding diabetic angiopathy has been slow, but we are now learning a number of lessons of interest to the cardiologist. Diabetic angiopathy is a collective term for conditions specific to the diabetic state and related to its duration more than to patient age. The angiopathy produces calcificatio...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/0002-8703(78)90053-4

    authors： McMillan DE

    更新日期：1978-09-01 00:00:00

  • Arrhythmia inducibility and ventricular vulnerability in a chronic feline infarction model.

    abstract：:Ventricular tachyarrhythmias are the cause of sudden cardiac death in ischemic heart disease. Reliable animal models are necessary to study techniques for identifying individuals at risk and to develop effective modes of therapy. The purpose of the present study was to evaluate the inducibility of ventricular tachyarr...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(85)90191-7

    authors： Wetstein L,Mark R,Kelliher GJ,Friehling T,O'Connor KM,Kowey PR

    更新日期：1985-11-01 00:00:00

  • Cardiac biomarker measurement after elective percutaneous coronary interventions in older patients: insights from the National Cardiovascular Data Registry.

    abstract：BACKGROUND:Guidelines recommend consideration of cardiac biomarker measurement after elective percutaneous coronary intervention (PCI), especially with complex cases or complicated procedures. However, the long-term prognostic implications of biomarker measurement after elective PCI have not been well characterized in ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2013.09.007

    authors： Wang TY,McCoy LA,Messenger JC,Neely ML,Ho KK,Roe MT,Anderson HV

    更新日期：2013-11-01 00:00:00

  • Primary prevention in patients with hypertension: comments on the clinical implications of the MAPHY Study. Metoprolol Atherosclerosis Prevention in Hypertensives Study.

    abstract：:The MAPHY Study was conducted to investigate whether metoprolol, a relatively beta 1-selective beta-blocker, given as initial antihypertensive treatment, would lower cardiovascular complications of high blood pressure to a greater extent than do thiazide diuretics as initial treatment at similar blood pressure control...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-8703(88)90112-3

    authors： Wikstrand J

    更新日期：1988-07-01 00:00:00

  • Effect of low doses of n-3 fatty acids on cardiovascular diseases in 4,837 post-myocardial infarction patients: design and baseline characteristics of the Alpha Omega Trial.

    abstract：BACKGROUND:Weekly fish consumption has been related to a lower risk of fatal coronary heart disease (CHD) and incident stroke in populations with a low fish intake. This relation has mainly been attributed to n-3 fatty acids in fish, that is, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). It is at present ...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2009.12.033

    authors： Geleijnse JM,Giltay EJ,Schouten EG,de Goede J,Oude Griep LM,Teitsma-Jansen AM,Katan MB,Kromhout D,Alpha Omega Trial Group.

    更新日期：2010-04-01 00:00:00

  • Efficacy and safety of dual antiplatelet therapy after coronary stenting in patients with chronic kidney disease.

    abstract：BACKGROUND:We compared efficacy and safety of short- (3 or 6 months) versus long-term (≥12 months) dual antiplatelet therapy (DAPT) after drug-eluting stent (DES) implantation, according to the presence of chronic kidney disease (CKD). METHODS:Patient-level pooled analysis was performed with 7242 patients (87.2% with ...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2017.11.013

    authors： Hwang D,Park KW,Lee JM,Rhee TM,Hong MK,Jang Y,Valgimigli M,Colombo A,Gilard M,Palmerini T,Stone GW,Kim HS

    更新日期：2018-03-01 00:00:00

  • Safety assessment of perflenapent emulsion for echocardiographic contrast enhancement in patients with congestive heart failure or chronic obstructive pulmonary disease.

    abstract：BACKGROUND:Perflenapent injectable emulsion is a newer echocardiographic contrast agent that provides chamber opacification and improved endocardial border delineation. In >1000 patients tested, adverse effects have been minimal. However, previous studies have included few patients with congestive heart failure (CHF) o...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1067/mhj.2000.106612

    authors： Kitzman DW,Wesley DJ

    更新日期：2000-06-01 00:00:00

  • Cardiac rehabilitation participation predicts lower rehospitalization costs.

    abstract：:The effect of participation in cardiac rehabilitation on medical costs was determined by measuring hospitalization charges for cardiac admissions over a 3-year period in 580 post-coronary event patients (58% after coronary bypass surgery, 42% after myocardial infarction), of whom 230 entered a cardiac rehabilitation p...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(92)90696-s

    authors： Ades PA,Huang D,Weaver SO

    更新日期：1992-04-01 00:00:00

  • Identification of the ischemic etiology of heart failure by cardiovascular magnetic resonance imaging: diagnostic accuracy of late gadolinium enhancement.

    abstract：BACKGROUND:A large proportion of patients with heart failure (HF) have a large and poorly contracting left ventricle. The noninvasive recognition of the ischemic etiology of such patients is difficult, and for this purpose, usually patients undergo coronary angiography. It has been shown that cardiovascular magnetic re...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2005.03.068

    authors： Casolo G,Minneci S,Manta R,Sulla A,Del Meglio J,Rega L,Gensini G

    更新日期：2006-01-01 00:00:00

  • Present state of alpha and beta adrenergic drugs. II. The adrenergic blocking agents.

    abstract：:There are selective blocking agents (antagonists) for alpha receptors and beta receptors. These blocking agents prevent the response to injected agonists and neurogenically released norepinephrine. The principal cardiovascular response to alpha blockade is postural hypotension with reflexly induced cardiac stimulation...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(76)80020-8

    authors： Ahlquist RP

    更新日期：1976-12-01 00:00:00

  • Abnormal mitral valve motion associated with ventricular septal defect following acute myocardial infarction.

    abstract：:It is often difficult to make the clinical distinction between acute mitral regurgitation caused by papillary muscle dysfunction or rupture and ventricular septal defect complicating an acute myocardial infarction. A case of a patient with rapidly progressive congestive heart failure and a loud murmur is presented. Ec...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/0002-8703(79)90291-6

    authors： Rosenthal R,Kleid JJ,Cohen MV

    更新日期：1979-11-01 00:00:00

  • Platelet activation in patients with congestive heart failure: do we have enough evidence to consider clopidogrel?

    abstract：:Our understanding of the pathogenesis of congestive heart failure (CHF) has improved remarkably in recent years. However, despite better knowledge and novel pharmaceutical strategies, this disease is still one of the most brutal killers in the Western world. The pathophysiology of CHF is complex, and much of our compr...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1067/mhj.2003.163

    authors： Malinin AI,O'Connor CM,Dzhanashvili AI,Sane DC,Serebruany VL

    更新日期：2003-03-01 00:00:00

  • Review of primary prevention trials.

    abstract：:The main threat to patients with mild to moderate hypertension is coronary heart disease (CHD), but controlled trials of antihypertensive drug therapy have given disappointing results: overall, the reduction in CHD mortality (11%) and morbidity (10%) were small and nonsignificant. Recent trials comparing a beta blocke...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章

    doi：10.1016/0002-8703(87)90602-8

    authors： Rose G

    更新日期：1987-10-01 00:00:00

  • Validation of an automated electronic algorithm and "dashboard" to identify and characterize decompensated heart failure admissions across a medical center.

    abstract：BACKGROUND:We aim to validate the diagnostic performance of the first fully automatic, electronic heart failure (HF) identification algorithm and evaluate the implementation of an HF Dashboard system with 2 components: real-time identification of decompensated HF admissions and accurate characterization of disease char...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2016.10.001

    authors： Cox ZL,Lewis CM,Lai P,Lenihan DJ

    更新日期：2017-01-01 00:00:00

  • Ten-year clinical follow-up after sirolimus-eluting stent implantation.

    abstract：BACKGROUND:Little is known on the "very" long-term incidence of major adverse cardiac events (MACE), target-lesion revascularization (TLR), target-vessel revascularization and stent thrombosis after sirolimus-eluting stent (SES) implantation. We present the first study to provide a 10-year clinical follow-up in an unse...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2013.12.013

    authors： Palhais N,Arroyo D,Lehmann S,Togni M,Kaufmann U,Puricel SG,Stauffer JC,Goy JJ,Cook S

    更新日期：2014-06-01 00:00:00

  • Assessment of diastolic function in normal and hypertrophied hearts: comparison of Doppler echocardiography and M-mode echocardiography.

    abstract：:Left ventricular (LV) filling was examined by Doppler and M-mode echocardiography in 24 patients with LV hypertrophy (five with aortic stenosis, six with hypertrophic cardiomyopathy, and 13 with LV hypertrophy secondary to systemic hypertension) and in 18 normal subjects. Patients with LV hypertrophy had significantly...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(87)90657-0

    authors： Pearson AC,Labovitz AJ,Mrosek D,Williams GA,Kennedy HL

    更新日期：1987-06-01 00:00:00

  • Clinical outcomes after percutaneous revascularization versus medical management in patients with significant renal artery stenosis: a meta-analysis of randomized controlled trials.

    abstract：BACKGROUND:We sought to systematically evaluate whether percutaneous revascularization is associated with additional clinical benefit in patients with renal artery stenosis (RAS) as compared with medical management alone. METHODS:We included randomized controlled trials that compared percutaneous revascularization in ...

    journal_title：American heart journal

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.ahj.2010.12.006

    authors： Kumbhani DJ,Bavry AA,Harvey JE,de Souza R,Scarpioni R,Bhatt DL,Kapadia SR

    更新日期：2011-03-01 00:00:00

  • Effects of nadolol treatment on renal and hepatic hemodynamics and function in cirrhotic patients with portal hypertension.

    abstract：:Twelve cirrhotic patients with portal hypertension and esophageal varices were treated with nadolol for 1 month, and the effects on renal and hepatic hemodynamics and function were studied. A significant decrease in cardiac output, portohepatic gradient, and effective hepatic blood flow was found, whereas mean arteria...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(84)90602-1

    authors： Gatta A,Sacerdoti D,Merkel C,Milani L,Battaglia G,Zuin R

    更新日期：1984-10-01 00:00:00

  • Evaluation of cardiac magnetic resonance imaging parameters to detect anatomically and hemodynamically significant coronary artery disease.

    abstract：BACKGROUND:Cardiac magnetic resonance (cMR) perfusion imaging is a promising technique to assess coronary artery disease (CAD). Our objective was to evaluate accuracy of various cMR imaging parameters to detect significant CAD as compared with angiography or fractional flow reserve (FFR). METHODS:We prospectively enro...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2007.04.024

    authors： Futamatsu H,Wilke N,Klassen C,Shoemaker S,Angiolillo DJ,Siuciak A,Morikawa-Futamatsu K,Suzuki N,von Ziegler F,Bass TA,Costa MA

    更新日期：2007-08-01 00:00:00