Primary prevention in patients with hypertension: comments on the clinical implications of the MAPHY Study. Metoprolol Atherosclerosis Prevention in Hypertensives Study.

abstract：BACKGROUND:Performing preoperative coronary angiography (CA) before surgical repair of a type A acute aortic dissection (TA-AAD) remains controversial. Although the information provided by CA may be useful in planning the surgical approach, the potential delay to surgery and complications of CA may confer added risk of...

journal_title：American heart journal

authors： Ramanath VS,Eagle KA,Nienaber CA,Isselbacher EM,Froehlich JB,Montgomery DG,Cooper JV,Gu X,Evangelista A,Voehringer M,Beckman J,Myrmel T,Pape L,Pyeritz RE,Hirsch AT,Gilon D,Bossone E

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to examine prospectively the incidence, predisposing cardiovascular conditions, and risk factors for sudden death in women compared with men. METHODS AND RESULT:The study design was a prospective general population examination of a cohort of 2873 women for development of sudd...

journal_title：American heart journal

authors： Kannel WB,Wilson PW,D'Agostino RB,Cobb J

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Myxomas, the most common cardiac tumor in adults, occur in the atria and are prone to embolization. Obstructive valvular tumors in infants occur in pulmonic and aortic valves and generally have a more benign course. METHODS:We conducted a review of our experience in infants with tumors obstructing the right...

journal_title：American heart journal

authors： Guntheroth WG,Fujioka MC,Reichenbach DD

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Among patients receiving thrombolytic therapy for myocardial infarction, the outcome for those with a history of infarction is dramatically worse than for those with their first event. Methods And Results We performed a post hoc analysis of patients with a history of myocardial infarction enrolled in the Glo...

journal_title：American heart journal

authors： Brieger DB,Mak KH,Miller DP,Califf RM,Topol EJ

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Anemia is now recognized as being a common finding in CHF and is associated with increased mortality and morbidity. However, it is uncertain whether the anemia is actually causing the worse prognosis or is merely a marker of more severe cardiac disease. Previous intervention studies with subcutaneous (s.c.) ...

journal_title：American heart journal

authors： Palazzuoli A,Silverberg D,Iovine F,Capobianco S,Giannotti G,Calabrò A,Campagna SM,Nuti R

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Complications of vascular access are one of the most common adverse events after coronary angiography and percutaneous coronary intervention (PCI) and are reported to occur in 1% to 9% of cases. There are conflicting reports of the association of vascular complications with the use of vascular closure device...

journal_title：American heart journal

authors： Arora N,Matheny ME,Sepke C,Resnic FS

更新日期：2007-04-01 00:00:00

abstract：:Repetitive 10-hour ECG recordings of 289 patients obtained within a year after myocardial infarction were analyzed for the presence of ventricular runs, and their association with various types of ventricular ectopic activity (VEA), average rate of premature ventricular complexes (PVCs), and coupling interval of PVCs ...

journal_title：American heart journal

authors： Thanavaro S,Kleiger RE,Miller JP,Province MA,Friedman E,Oliver GC

更新日期：1983-09-01 00:00:00

abstract：:The aim of this prospective study was to compare the short-term reproducibility of the signal-averaged ECG (SAECG) with three analysis techniques, conventional time-domain analysis, spectral-temporal mapping (STM), and spectral-turbulence analysis (STA), in a large series of normal subjects and patients with acute myo...

journal_title：American heart journal

authors： Vázquez R,Caref EB,Torres F,Reina M,Ortega F,el-Sherif N

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:The study aimed to compare the short-term costs and long-term cost-effectiveness of 2 antithrombotics, fondaparinux and enoxaparin, for non-ST-elevation acute coronary syndrome in the United States. METHODS:It was based on a large randomized trial of 20,078 patients Fifth Organization to Assess Strategies i...

journal_title：American heart journal

authors： Sculpher MJ,Lozano-Ortega G,Sambrook J,Palmer S,Ormanidhi O,Bakhai A,Flather M,Steg PG,Mehta SR,Weintraub W

更新日期：2009-05-01 00:00:00

abstract：:To determine whether a dose of 5 mg of nifedipine would be useful in the treatment of hypertensive emergencies, we compared the acute hypotensive effects of two different doses of nifedipine, 5 mg and 10 mg, in patients with severe hypertension. In this prospective, randomized, double-blind study, 30 consecutive black...

journal_title：American heart journal

authors： Maharaj B,van der Byl K

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:The prodrug clopidogrel requires activation by cytochrome P-450 (CYP) enzymes for its antiplatelet effect. The genes encoding enzymes for clopidogrel activation are polymorphic, leading to reduced or increased function, depending on the respective genotype. Reduced-function alleles have been associated with ...

journal_title：American heart journal

authors： Tiroch KA,Sibbing D,Koch W,Roosen-Runge T,Mehilli J,Schömig A,Kastrati A

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The follow-up of patients with mitral and tricuspid regurgitation is important for their clinical treatment. We aimed to evaluate the reproducibility of the flow convergence method in mitral and tricuspid regurgitation. METHODS:The proximal flow convergence region was imaged with color Doppler ultrasound sc...

journal_title：American heart journal

authors： Grossmann G,Hoffmeister A,Imhof A,Giesler M,Hombach V,Spiess J

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:A common regimen for patients requiring dual-antiplatelet therapy who are at risk for gastrointestinal complications is the synchronous administration of enteric-coated (EC) aspirin, a proton pump inhibitor, and clopidogrel, although proton pump inhibitors have the potential for pharmacodynamic interaction w...

journal_title：American heart journal

authors： Gurbel PA,Bliden KP,Fort JG,Jeong YH,Shuldiner A,Chai S,Gesheff T,Antonino M,Gesheff M,Zhang Y,Tantry US

更新日期：2013-02-01 00:00:00

abstract：:To investigate the mechanisms of restenosis and detect useful interventions to prevent it, reliable quantitative measurements must be evaluated. Coronary arteries of domestic and minipigs (n = 18) were mechanically injured by balloon overstretching and killed at different intervals (2 to 25 weeks) after quantitative a...

journal_title：American heart journal

authors： Bonan R,Paiement P,Scortichini D,Cloutier MJ,Leung TK

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:The study evaluates whether Optison used during dobutamine stress echocardiography (DSE) will improve endocardial border definition and whether this will translate to an improvement in sensitivity and specificity of the test in patients with poor echocardiographic windows. DSE is extremely valuable in the wo...

journal_title：American heart journal

authors： Dolan MS,Riad K,El-Shafei A,Puri S,Tamirisa K,Bierig M,St Vrain J,McKinney L,Havens E,Habermehl K,Pyatt L,Kern M,Labovitz AJ

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:There is growing interest in assessing therapy for acute myocardial infarction. Because thrombolysis was not a study therapy in the GISSI-3 trial, the decision about thrombolysis was left to the responsible physicians. We evaluated the data on thrombolytic therapy among patients with acute myocardial infarct...

journal_title：American heart journal

authors： Bobbio M,Bergerone S,Maggioni AP,Malacrida R,Franzosi MG,Barlera S,Tognoni G,GISSI-3 Investigators.

更新日期：1998-03-01 00:00:00

abstract：:The possibility of demonstrating noninvasively with C-11 palmitate and positron emission tomography (PET) changes in myocardial substrate metabolism in normal and diseased human myocardium in response to altered substrate availability in blood and disease-related abnormalities was examined in five normal volunteers an...

journal_title：American heart journal

authors： Schelbert HR,Henze E,Sochor H,Grossman RG,Huang SC,Barrio JR,Schwaiger M,Phelps ME

更新日期：1986-06-01 00:00:00

abstract：:An 84-year-old female who previously underwent repair of an atrial septal defect had evidence of increased reflectiveness of the posterior tricuspid anulus in the apical four-chamber view and the right ventricular two-chamber view. In addition, the inferior vena cava was dilated and during contrast echocardiography, c...

journal_title：American heart journal

authors： Mattleman S,Panidis I,Kotler MN,Mintz GS,Morganroth J,Ross J,Victor M

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:The pulmonary venous flow signal measured by transesophageal echocardiography is generally recorded from the left upper pulmonary vein in the left lateral decubitus position, whereas that by transthoracic echocardiography is from the right upper pulmonary vein in the left semi-lateral decubitus position. The...

journal_title：American heart journal

authors： Izumi C,Iga K,Himura Y,Gen H,Konishi T

更新日期：1999-03-01 00:00:00

abstract：:Fifty adult men with mild to moderate hypertension were recruited to participate in a double-blind crossover study. Each subject received 14 days of drug treatment and 14 days of placebo treatment (random order). Half the subjects were assigned to a metoprolol (150 mg/day) vs placebo treatment regimen and half to an a...

journal_title：American heart journal

authors： Streufert S,DePadova A,McGlynn T,Pogash R,Piasecki M

更新日期：1988-07-01 00:00:00

abstract：INTRODUCTION:It has been demonstrated that skin tissue cholesterol (SkinTc) is associated with angiographic disease. Now, we further delineate the relative risk of multivessel disease (>50% stenosis in at least two vessels) in the conjoint presence of high SkinTc and high traditional risk burden. METHODS:Patients sche...

journal_title：American heart journal

authors： Sprecher DL,Pearce GL

更新日期：2006-10-01 00:00:00

abstract：:The effects of amiodarone on delayed afterdepolarization (DAD) and triggered automaticity induced by low potassium (0.5 mEq/L) were evaluated on isolated rabbit right ventricular muscles, by means of standard microelectrode techniques. Triggered automaticity was induced in 6 of 10 muscles in the control group, in four...

journal_title：American heart journal

authors： Ohta M,Karagueuzian HS,Mandel WJ,Peter T

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:The timely and accurate identification of symptoms of acute coronary syndrome (ACS) is a challenge for patients and clinicians. It is unknown whether response times and clinical outcomes differ with specific symptoms. We sought to identify which ACS symptoms are related-symptom clusters-and to determine if s...

journal_title：American heart journal

authors： Riegel B,Hanlon AL,McKinley S,Moser DK,Meischke H,Doering LV,Davidson P,Pelter MM,Dracup K

更新日期：2010-03-01 00:00:00

abstract：:A study of nonbacterial thrombotic endocarditis has been carried out in a series of 3,404 autopsies performed upon atomic bomb survivors in Hiroshima in the period 1953-1970. The prevalence of the lesion was 2.4 per cent, with a greater frequency among the elderly and among females, and with a significant relationship...

journal_title：American heart journal

authors： Chino F,Kodama A,Otake M,Dock DS

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is associated with increased risk of death, thromboembolic complications, and a lowered quality of life. Despite this burden, pharmacologic agents for prevention of AF in patients who achieved normal sinus rhythm are of limited utility, mostly because of serious and frequent side eff...

journal_title：American heart journal

authors： Macchia A,Varini S,Grancelli H,Nul D,Laffaye N,Ferrante D,Tognoni G,Doval HC,FORomegaARD investigators.

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Drug-eluting stents (DES) have largely replaced bare-metal stents (BMS) for percutaneous coronary intervention (PCI). It is uncertain, however, whether introduction of DES had a significant impact on the comparative effectiveness of PCI versus coronary artery bypass graft surgery (CABG) for death and myocard...

journal_title：American heart journal

authors： Hlatky MA,Boothroyd DB,Baker LC,Go AS

更新日期：2015-01-01 00:00:00

abstract：:It has been shown that brief episodes of myocardial ischemia can render the heart more resistant to a prolonged subsequent ischemic episode. This phenomenon, called "preconditioning," has been described in human beings during coronary angioplasty with the use of clinical, electrocardiographic (ECG), or metabolic param...

journal_title：American heart journal

authors： Eltchaninoff H,Cribier A,Tron C,Derumeaux G,Koning R,Hecketsweiller B,Letac B

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Clinical trials have helped clarify the efficacy of clopidogrel for the treatment and prevention of vascular disease. Costs for its use exceeded $5.9 billion in 2005, making it the second greatest source of drug expenditure in the world. However, little is known about the appropriateness of that use. Overuse...

journal_title：American heart journal

authors： Choudhry NK,Levin R,Avorn J

更新日期：2008-05-01 00:00:00

abstract：:Functional, ambulatory, community-dwelling subjects (n = 423, aged 75 to 85 years) underwent baseline 24-hour ambulatory electrocardiography (ECG) examinations as part of the Bronx Aging Study, a 10-year prospective cohort study designed to identify risk factors and disease markers for cardiovascular, cerebrovascular,...

journal_title：American heart journal

authors： Frishman WH,Heiman M,Karpenos A,Ooi WL,Mitzner A,Goldkorn R,Greenberg S

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Women with X-chromosome monosomy or Turner syndrome (TS) are at increased risk for aortic dilation and dissection. To better understand the pathology and develop tools to monitor the risk of aortic disease, we investigated N-terminal pro-brain natriuretic peptide (BNP) (NT-proBNP) levels in women with TS and...

journal_title：American heart journal

authors： Gutin LS,Bakalov VK,Rosing DR,Arai AE,Gharib AM,Bondy CA

更新日期：2012-09-01 00:00:00