Present state of alpha and beta adrenergic drugs. II. The adrenergic blocking agents.

abstract：BACKGROUND:Systolic wall motion abnormality (WMA) after acute myocardial infarction (AMI) is a major determinant of outcome; the presence and importance of diastolic WMA after AMI are unknown. We therefore sought to detect diastolic WMA using color kinesis and to assess its relation to neurohormonal activation and its ...

journal_title：American heart journal

authors： Husic M,Nørager B,Egstrup K,Lang RM,Møller JE

更新日期：2005-10-01 00:00:00

abstract：:The prevalence of heart failure (HF) is high and still on the rise. In 2004, an estimated 5.2 million adults in the United States carried the diagnosis of HF with a mortality rate of >19%. The incidence of HF is higher in individuals 65 years or older. As the US population grows older, the personal and economic costs ...

journal_title：American heart journal

authors： Gradman AH,Papademetriou V

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Calcified lesions carry the risk of suboptimal stent expansion. The purpose of this study was to investigate the impact of target lesion calcification on intracoronary ultrasound (ICUS) guided stent expansion after rotational atherectomy. METHODS:Stent expansion was assessed by ICUS in 39 patients with the ...

journal_title：American heart journal

authors： Henneke KH,Regar E,König A,Werner F,Klauss V,Metz J,Theisen K,Mudra H

更新日期：1999-01-01 00:00:00

abstract：:Fenoldopam mesylate (SK&F 82526-J) is a novel benzazepine derivative. It has selective agonist activity at post-junctional (DA1) vascular dopaminergic receptors, which normally subserve renal artery vasodilation. Previous studies in normal subjects and in patients with hypertension indicate that fenoldopam increases r...

journal_title：American heart journal

authors： Francis GS,Wilson BC,Rector TS

更新日期：1988-08-01 00:00:00

abstract：:We aimed to investigate long-term (≥5 years) outcomes of percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG) for left main coronary artery disease (LMCAD) using a meta-analysis from updated published randomized trials. Our data showed that the risk of all-cause death as well as cardi...

journal_title：American heart journal

authors： Kuno T,Ueyama H,Rao SV,Cohen MG,Tamis-Holland JE,Thompson C,Takagi H,Bangalore S

更新日期：2020-09-01 00:00:00

abstract：:Interatrial septal aneurysm (IASA) has been detected with increasing frequency since the advent of two-dimensional echocardiography (2DE). In this study, we investigated the prevalence, characteristics, and predisposing factors in IASA formation in 724 infants, children, and adolescents undergoing 2DE. Among this grou...

journal_title：American heart journal

authors： Wolf WJ,Casta A,Sapire DW

更新日期：1987-05-01 00:00:00

abstract：:Recent developments have highlighted the challenges facing cardiovascular clinical research in global contemporary practice, particularly in North America, including shifting priorities for drug development targets, increasing regulatory requirements, and expensive operational approaches for conducting randomized clin...

journal_title：American heart journal

authors： Roe MT,Mahaffey KW,Ezekowitz JA,Alexander JH,Goodman SG,Hernandez A,Temple T,Berdan L,Califf RM,Harrington RA,Peterson ED,Armstrong PW

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The benefits of intra-aortic balloon pumping (IABP) usage reportedly occur through systolic unloading of the left ventricle and the augmentation of diastolic coronary flow. The aim of this study was to assess the change in intracoronary pressure distal to the coronary stenosis after the IABP by using an intr...

journal_title：American heart journal

authors： Yoshitani H,Akasaka T,Kaji S,Kawamoto T,Kume T,Neishi Y,Koyama Y,Yoshida K

更新日期：2007-10-01 00:00:00

abstract：:Our experience with the use of five new antiarrhythmic drugs for treating life-threatening arrhythmias in children will be briefly reviewed. Prevention of recurrent episodes of atrial flutter with digoxin and local anesthetic antiarrhythmic drugs often is only moderately successful, benefiting 65% of patients. Amiodar...

journal_title：American heart journal

authors： Moak JP,Smith RT,Garson A Jr

更新日期：1987-01-01 00:00:00

abstract：:The recognition that the onset of cardiovascular events follows a circadian periodicity and is frequently triggered by physical or mental stresses has created new possibilities for disease prevention. Morning peaks in occurrence are now well-documented for acute myocardial infarction, sudden cardiac death, transient m...

journal_title：American heart journal

authors： Muller JE

更新日期：1999-04-01 00:00:00

abstract：:In patients with essential hypertension, glomerular filtration rate remains normal or elevated, whereas renal blood flow tends to be lower, which results in an increased filtration fraction. The afferent (preglomerular) arteriolar resistance determines the fraction of the pressure that is transmitted to the glomerular...

journal_title：American heart journal

authors： Larochelle P

更新日期：1991-10-01 00:00:00

abstract：:Percutaneous coronary interventions have been performed for 20 years. Despite the success and progress of these interventions, abrupt vessel closure has been a dramatic adverse event of coronary interventions. Closure has frequently led to the major complications of death, myocardial infarction, and emergency coronary...

journal_title：American heart journal

authors： Bergelson BA,Fishman RF,Tommaso CL

更新日期：1997-09-01 00:00:00

abstract：:Characteristics of color-coded Doppler imaging combined with two-dimensional and M-mode echocardiography in six patients with systolic-diastolic murmurs are reported. PDA, congenital absence of pulmonary valve leaflets, ventricular septal defect and aortic regurgitation, two ruptured aneurysms of sinus of Valsalva, an...

journal_title：American heart journal

authors： Vargas-Barron J,Attie F,Skronme D,Sanchez-Ugarte T,Keirns C,Santana-Gonzalez A

更新日期：1987-12-01 00:00:00

abstract：:The P and the Ta waves of two patient groups with A-V block were magnified with a direct-current amplifier and recorded at a high paper speed. In Group A patients (those without serious cardiovascular complications except A-V block) the P and the Ta waves were recorded in the opposite direction in every lead and there...

journal_title：American heart journal

authors： Hayashi H,Okajima M,Yamada K

更新日期：1976-06-01 00:00:00

abstract：:To understand the process of atherosclerosis, the homeostatic and protective functions of the endothelium must be considered. The endothelium serves as the interface between blood flow and the vascular tissues. It normally regulates vascular tone and structure through the release of vasoactive substances and maintenan...

journal_title：American heart journal

authors： Dzau VJ

更新日期：1994-12-01 00:00:00

abstract：:The efficacy of mexiletine used alone, and in combination with a class Ia antiarrhythmic drug, was assessed in 159 previously drug-refractory patients with ventricular tachycardia (VT) during serial electrophysiologic studies and during long-term (5-year) clinical follow-up. Electrically-inducible ventricular tachycar...

journal_title：American heart journal

authors： Whitford EG,McGovern B,Schoenfeld MH,Garan H,Newell JB,McElroy M,Ruskin JN

更新日期：1988-02-01 00:00:00

abstract：AIM:The EARISA Registry was designed to describe diagnostic and therapeutic resources used in Italian cardiology centers for patients with the epidemiologically most relevant cardiac diseases. This article focuses on patients with unstable angina; characteristics associated with invasive procedures were specifically an...

journal_title：American heart journal

authors： Maggioni AP,Schweiger C,Tavazzi L,Langiano T,Lucci D,Ramponi C,Repetto F,De Vita C

更新日期：2000-08-01 00:00:00

abstract：:Sodium-glucose cotransporter 2 inhibitor (SGLT2i) use is associated with improved cardiovascular and kidney outcomes. However, the magnitude and potential heterogeneity of effect across patients with varying types of cardiometabolic and kidney disease is unclear. To examine the effect of SGLT2i on cardiovascular and k...

journal_title：American heart journal

authors： Salah HM,Al'Aref SJ,Khan MS,Al-Hawwas M,Vallurupalli S,Mehta JL,Mounsey JP,Greene SJ,McGuire DK,Lopes RD,Fudim M

更新日期：2021-02-01 00:00:00

abstract：:To evaluate the therapeutic efficacy of oral angiotensin-converting inhibition (ACE) with captopril in chronic normotensive congestive heart failure (CHF), acute and cardiocirculatory actions were determined by cardiac catheterization and forearm plethysmography, and ambulatory effects were assessed by echocardiograph...

journal_title：American heart journal

authors： Awan NA,Evenson MK,Needham KE,Win A,Mason DT

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:To assess whether serum uric acid, which is a marker of impaired oxidative metabolism, might correlate with left ventricular systolic and diastolic dysfunction in patients with chronic heart failure (CHF). BACKGROUND:Uric acid levels, which are frequently elevated in patients with CHF, correlate with leg vas...

journal_title：American heart journal

authors： Cicoira M,Zanolla L,Rossi A,Golia G,Franceschini L,Brighetti G,Zeni P,Zardini P

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Multidisciplinary disease management programs (MDMP) have demonstrated reduced hospitalizations in motivated pretransplant heart failure populations, but little is known about their effectiveness in largely indigent patients who are not transplant candidates. METHODS AND RESULTS:We studied 35 patients with ...

journal_title：American heart journal

authors： O'Connell AM,Crawford MH,Abrams J

更新日期：2001-02-01 00:00:00

abstract：:Repetitive 10-hour ECG recordings of 289 patients obtained within a year after myocardial infarction were analyzed for the presence of ventricular runs, and their association with various types of ventricular ectopic activity (VEA), average rate of premature ventricular complexes (PVCs), and coupling interval of PVCs ...

journal_title：American heart journal

authors： Thanavaro S,Kleiger RE,Miller JP,Province MA,Friedman E,Oliver GC

更新日期：1983-09-01 00:00:00

abstract：:Plasma cholesterol levels were measured in 15,892 participants of a cholesterol screening in Hartford, Connecticut. The screenees were typically health conscious as evidenced by the low prevalence of current cigarette smoking (12%). However, more than 25% of the men and 35% of the women over the age of 50 years had ch...

journal_title：American heart journal

authors： Wynder EL,Harris RE,Haley NJ

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:The relationship of changes in weight to outcomes in patients after myocardial infarction (MI) is controversial. METHODS:From the ENRICHD trial data, we assessed weight change, and the associations of baseline weight and change at follow-up with outcomes and interactions between psychosocial factors. RESUL...

journal_title：American heart journal

authors： Lopez-Jimenez F,Wu CO,Tian X,O'Connor C,Rich MW,Burg MM,Sheps D,Raczynski J,Somers VK,Jaffe AS

更新日期：2008-03-01 00:00:00

abstract：:Antiplatelet therapy is the current criterion standard for the treatment of patients undergoing percutaneous coronary intervention and patients who have acute coronary syndromes. Clopidogrel in combination with aspirin is the current standard of care for reducing cardiovascular events in these patients. However, patie...

journal_title：American heart journal

authors： Angiolillo DJ,Guzman LA,Bass TA

更新日期：2008-08-01 00:00:00

abstract：:The actions of the beta-adrenergic receptor antagonist, d,l-nadolol, were examined in anesthetized dogs subjected to circumflex coronary artery ligation in the presence of previous anterior myocardial infarction. With circumflex ligation, control dogs (N = 18) developed premature ventricular beats and ventricular tach...

journal_title：American heart journal

authors： Patterson E,Lucchesi BR

更新日期：1988-11-01 00:00:00

abstract：:We tested the efficacy of microwave-frequency energy for ablating atrial tachycardia in eight open-chest dogs. Five other dogs served as controls. Atrial tachycardia was induced by direct application of aconitine crystals to the epicardial atrial surface or by injection of aconitine solution (0.15 mg/ml) into the righ...

journal_title：American heart journal

authors： Rho TH,Ito M,Pride HP,Waller B,Zipes DP

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:We aim to validate the diagnostic performance of the first fully automatic, electronic heart failure (HF) identification algorithm and evaluate the implementation of an HF Dashboard system with 2 components: real-time identification of decompensated HF admissions and accurate characterization of disease char...

journal_title：American heart journal

authors： Cox ZL,Lewis CM,Lai P,Lenihan DJ

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Trimethylamine N-oxide (TMAO), a gut-related metabolite, is associated with heart failure (HF) outcomes. However, TMAO is the final product of a complex metabolic pathway (ie, choline/carnitine) that has never been entirely investigated in HF. The present study investigates a panel of metabolites involved in...

journal_title：American heart journal

authors： Israr MZ,Bernieh D,Salzano A,Cassambai S,Yazaki Y,Heaney LM,Jones DJL,Ng LL,Suzuki T

更新日期：2021-01-14 00:00:00

abstract：:The clinical spectrum and outcome of 119 patients with acute non-Q wave myocardial infarction (NQMI) were studied, in comparison with those of 354 patients with acute Q wave myocardial infarction (QMI). The patients with NQMI had a significantly higher incidence of preinfarction angina (73% vs 63%), previous myocardia...

journal_title：American heart journal

authors： Ogawa H,Hiramori K,Haze K,Saito M,Sumiyoshi T,Fukami K,Goto Y,Ikeda M

更新日期：1986-03-01 00:00:00