Current antiplatelet therapies: benefits and limitations.

abstract：:Plasma cholesterol levels were measured in 15,892 participants of a cholesterol screening in Hartford, Connecticut. The screenees were typically health conscious as evidenced by the low prevalence of current cigarette smoking (12%). However, more than 25% of the men and 35% of the women over the age of 50 years had ch...

journal_title：American heart journal

authors： Wynder EL,Harris RE,Haley NJ

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Treatment strategies, either invasive or noninvasive, for patients with unstable coronary artery disease still vary. There are no published studies comparing the strategies for health-related quality of life. METHODS:A total of 2457 patients with unstable coronary artery disease were randomized. We prospect...

journal_title：American heart journal

authors： Janzon M,Levin LA,Swahn E

更新日期：2004-07-01 00:00:00

abstract：:Left ventricular angiography frequently produces one or more premature atrial or ventricular contractions which may make quantitative volume analysis unreliable. Three hundred left ventricular power injections were analyzed and found to produce premature ventricular contractions (PVC's) in 28 per cent of injections an...

journal_title：American heart journal

authors： Caldwell JH,Kennedy JW

更新日期：1977-02-01 00:00:00

abstract：:A multiprogrammable automatic antitachycardia pacemaker (Cybertach-60), connected to a tined "J" wire electrode, was positioned in the right atrial appendage in three patients with recurrent supraventricular tachycardia (SVT). Mechanisms of SVT included atrioventricular (AV) nodal reentry (two patients) and reciprocat...

journal_title：American heart journal

authors： Lerman BB,Waxman HL,Buxton AE,Sweeney M,Josephson ME

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:This study investigates whether pioglitazone reduces neointimal hyperplasia after coronary stenting in nondiabetic patients with metabolic syndrome (MS) using intravascular ultrasound (IVUS). Pioglitazone, a novel insulin-sensitizing thiazolidinedione, has been shown to reduce neointimal hyperplasia after co...

journal_title：American heart journal

authors： Katayama T,Ueba H,Tsuboi K,Kubo N,Yasu T,Kuroki M,Saito M,Momomura S,Kawakami M

更新日期：2007-05-01 00:00:00

abstract：:In the United States there has been a dramatic decrease in age-adjusted coronary heart disease (CHD) mortality during the last 20 years. This article investigates the reasons for this decline and concludes that most of the decline in CHD has been the result of life-style changes, particularly reduction in serum choles...

journal_title：American heart journal

authors： Goldman L

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:The optimal duration of dual antiplatelet therapy (DAPT) in acute coronary syndrome (ACS) patients treated with drug eluting stents (DES) is still under debate. Recent meta-analyses on ≤6months versus 12months DAPT suggest that bleeding rates can be reduced, without a higher rate of thrombotic complications....

journal_title：American heart journal

authors： Camaro C,Damen SA,Brouwer MA,Kedhi E,Lee SW,Verdoia M,Barbieri L,Rognoni A,van T Hof AW,Ligtenberg E,de Boer MJ,Suryapranata H,De Luca G

更新日期：2016-08-01 00:00:00

abstract：:Patients with intractable heart failure (New York Heart Association [NYHA] class III and IV) who were receiving maximal conventional treatment were enrolled in an outpatient program that included inotropic infusions, intensive patient education, and close follow-up. The effects of this approach to therapy were evaluat...

journal_title：American heart journal

authors： Marius-Nunez AL,Heaney L,Fernandez RN,Clark WA,Ranganini A,Silber E,Denes P

更新日期：1996-10-01 00:00:00

abstract：:Late potentials have been shown to predict malignant ventricular arrhythmias and sudden cardiac death. To determine whether prolonged, strenuous activity is associated with the development of ventricular late potentials, signal-averaged electrocardiography was performed on 30 marathon runners before, immediately after...

journal_title：American heart journal

authors： Smith GS,Vacek JL,Wilson DB,Hawkins JW,Boyer TA

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Despite some concern that recent aspirin ingestion increases blood loss after coronary artery surgery, there is some evidence that this may reduce thrombotic complications. In contrast, antifibrinolytic drugs can reduce blood loss in this setting, but there is concern that they may increase thrombotic compli...

journal_title：American heart journal

authors： Myles PS,Smith J,Knight J,Cooper DJ,Silbert B,McNeil J,Esmore DS,Buxton B,Krum H,Forbes A,Tonkin A,ATACAS Trial Group.

更新日期：2008-02-01 00:00:00

abstract：:The rate and form of creatine kinase-MB (CK-MB) enzyme release following reflow to ischemic myocardium has not been specifically examined in man. In this investigation, we examined the combined CK-MB time-activity curves during acute transmural myocardial infarction (AMI) in a group of patients receiving conventional ...

journal_title：American heart journal

authors： Shell W,Mickle DK,Swan HJ

更新日期：1983-10-01 00:00:00

abstract：:Compared with pathologic studies coronary angiography is a relatively insensitive technique to detect early atherosclerosis. Coronary angioscopy is a new technique providing direct information on luminal vessel surface. To determine whether coronary angioscopy may detect the presence of atherosclerotic disease on angi...

journal_title：American heart journal

authors： Alfonso F,Goicolea J,Hernandez R,Segovia J,Silva JC,Perez-Vizcayno MJ,Rollan MJ,Bañuelos C,Macaya C

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:The long-term effects of smoking and smoking cessation on markers of cardiovascular disease (CVD) prognosis obtained during treadmill stress testing (TST) are unknown. The purpose of this study was to evaluate the long-term effects of smoking cessation and continued smoking on TST parameters that predict CVD...

journal_title：American heart journal

authors： Asthana A,Piper ME,McBride PE,Ward A,Fiore MC,Baker TB,Stein JH

更新日期：2012-01-01 00:00:00

abstract：:Thiazides produce an average loss of 2 L of extracellular fluid volume, of which about 300 ml is plasma volume, during the first 48 hours of administration, and this reduction is maintained without further loss for as long as the drug is given. Do thiazides lower blood pressure by volume depletion or by direct vasodil...

journal_title：American heart journal

authors： Freis ED

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Atrioventricular septal defect (AVSD) and double outlet right ventricle (DORV) with normally related great arteries and normal ventricular sizes are associated with a good long-term prognosis after biventricular (BV) repair. The outcome of cases with a borderline small left ventricle (bLV) is unclear. The pu...

journal_title：American heart journal

authors： Pitkänen OM,Hornberger LK,Miner SE,Mondal T,Smallhorn JF,Jaeggi E,Nield LE

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Long-term treatment with beta-blockers reduces mortality after acute myocardial infarction (AMI). Whether beta-blockers exert a class effect is unknown. METHODS:We analyzed mortality after AMI in Canadian patients 65 years or older who were discharged from hospital with a diagnosis of AMI from April 1996 to...

journal_title：American heart journal

authors： Rinfret S,Abrahamowicz M,Tu J,Humphries K,Eisenberg MJ,Richard H,Austin PC,Pilote L

更新日期：2007-02-01 00:00:00

abstract：:The conducting tissue of the heart was studied in 25 human cases of Chagas' myocarditis with a method which employs complete serial sections mounted on continuous transparent plastic tape. The pathological changes were correlated with electrocardiographic findings. The inflammation of the acute phase of Chagas' myocar...

journal_title：American heart journal

authors： Andrade ZA,Andrade SG,Oliveira GB,Alonso DR

更新日期：1978-03-01 00:00:00

abstract：:To test alterations in plasma potassium and magnesium levels with maximal exercise, 15 sedentary, healthy men (mean age 29 years) participated in a double-blind crossover study for 11 weeks with propranolol, atenolol, and placebo. Maximal exercise tests were done at baseline and after placebo and beta-blockade phases....

journal_title：American heart journal

authors： Fletcher GF,Sweeney ME,Fletcher BJ

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Current practice related to the management of atrial fibrillation (AF) complicating coronary artery bypass grafting (CABG) is uncertain. METHODS:We examined management of post-CABG AF in the PREVENT-IV trial, and we explored patterns of use of postoperative rhythm versus rate control and anticoagulation for...

journal_title：American heart journal

authors： Al-Khatib SM,Hafley G,Harrington RA,Mack MJ,Ferguson TB,Peterson ED,Califf RM,Kouchoukos NT,Alexander JH

更新日期：2009-11-01 00:00:00

abstract：:In this study we have performed human leukocyte antigen (HLA)-A and B typing on nine patients with hypertrophic cardiomyopathy (HCM) and their relatives. Four patients had relatives who also had the disease. HLA typing of the familial form of HCM revealed a very close association of a given HLA-A,B haplotype with the ...

journal_title：American heart journal

authors： Kishimoto C,Kaburagi T,Takayama S,Yokoyama S,Hanyu I,Takatsu Y,Tomimoto K

更新日期：1983-06-01 00:00:00

abstract：:Currently, automated systems for quantitative analysis by intracoronary ultrasound (ICUS) are restricted to the detection of the lumen. The aim of this study was to determine the accuracy and reproducibility of a new semiautomated contour detection method, providing off-line identification of the intimal leading edge ...

journal_title：American heart journal

authors： von Birgelen C,Di Mario C,Li W,Schuurbiers JC,Slager CJ,de Feyter PJ,Roelandt JR,Serruys PW

更新日期：1996-09-01 00:00:00

abstract：:Increased intracellular calcium (calcium overload) is considered one of the factors that can initiate ventricular fibrillation. In addition, ventricular fibrillation itself can cause and possibly maintain calcium overload. The goal of this study was to determine whether the class IA antiarrhythmic agent procainamide c...

journal_title：American heart journal

authors： Zaugg CE,Wu ST,Kojima S,Wikman-Coffelt J,Parmley WW,Buser PT

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Several studies have shown that patency of the epicardial vessel does not guarantee optimal myocardial perfusion in patients undergoing primary angioplasty for ST-segment elevation myocardial infarction (STEMI). The aim of the current study was to identify clinical and angiographic correlates of unsuccessful...

journal_title：American heart journal

authors： De Luca G,van 't Hof AW,Ottervanger JP,Hoorntje JC,Gosselink AT,Dambrink JH,Zijlstra F,de Boer MJ,Suryapranata H

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Percutaneous coronary intervention (PCI) of saphenous vein graft (SVG) is associated with frequent postprocedural enzyme elevation and late cardiac events. New strategies are proposed to minimize distal embolization and to improve the outcome of patients treated with stenting for SVG lesions. The objectives ...

journal_title：American heart journal

authors： Leborgne L,Cheneau E,Pichard A,Ajani A,Pakala R,Yazdi H,Satler L,Kent K,Suddath WO,Pinnow E,Canos D,Waksman R

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Relationships between long-term use and level of dual antiplatelet therapy and outcomes after drug-eluting stent implantation are not well established. METHODS:This is a retrospective cohort study of 9,256 patients receiving drug-eluting stents between January 2003 and August 2006. We classified patients ac...

journal_title：American heart journal

authors： Petersen JL,Barron JJ,Hammill BG,Cziraky MJ,Anstrom KJ,Wahl PM,Eisenstein EL,Krucoff MW,Califf RM,Schulman KA,Curtis LH

更新日期：2010-03-01 00:00:00

abstract：:Three cases of rupture of the interventricular septum occurring coincident with acute inferior myocardial infarction are reported and the relevant literature is reviewed. One patient under-went successful surgical repair and, in addition, had an aneurysmectomy. Clues and pitfalls in diagnosis as well as the possible c...

journal_title：American heart journal

authors： Longo EA,Cohen LS

更新日期：1976-07-01 00:00:00

abstract：OBJECTIVE:To analyze the effect of delay times on racial differences in thrombolysis for acute myocardial infarction. BACKGROUND:Lower rates of thrombolytic therapy in blacks with acute myocardial infarction have recently been reported, but the reasons for this disparity are unknown. We hypothesized that lower rates o...

journal_title：American heart journal

authors： Syed M,Khaja F,Rybicki BA,Wulbrecht N,Alam M,Sabbah HN,Goldstein S,Borzak S

更新日期：2000-10-01 00:00:00

abstract：:We assessed the safety of early (2 to 4 days) intravenous dipyridamole infusion in conjunction with technetium 99m sestamibi tomographic myocardial perfusion imaging in patients with first myocardial infarction (MI). Early risk stratification with myocardial perfusion imaging of patients after acute MI may be useful t...

journal_title：American heart journal

authors： Heller GV,Brown KA,Landin RJ,Haber SB

更新日期：1997-07-01 00:00:00

abstract：:Left circumflex coronary blood flow was increased significantly (20 per cent) during stimulation of somatic afferent fibers. The change in CBF was associated with significant increases in heart rate and arterial pressure and significant decrease in coronary vascular resistance. Controlling heart rate or preventing car...

journal_title：American heart journal

authors： Kline RL

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:The independent prognostic value of blood pressure (BP) variability in essential hypertension and particularly in uncomplicated mild hypertension is not yet completely clear. We investigated the relationship between BP variability, evaluated by noninvasive monitoring, and cardiovascular outcome in uncomplica...

journal_title：American heart journal

authors： Pierdomenico SD,Lapenna D,Bucci A,Manente BM,Mancini M,Cuccurullo F,Mezzetti A

更新日期：2005-05-01 00:00:00