当前位置： SCI文献检索 > AMERICAN HEART JOURNAL期刊下所有文献 > Long-term effects of smoking and smoking cessation on exercise stress testing: three-year outcomes from a randomized clinical trial.

Long-term effects of smoking and smoking cessation on exercise stress testing: three-year outcomes from a randomized clinical trial.

Abstract：

BACKGROUND:The long-term effects of smoking and smoking cessation on markers of cardiovascular disease (CVD) prognosis obtained during treadmill stress testing (TST) are unknown. The purpose of this study was to evaluate the long-term effects of smoking cessation and continued smoking on TST parameters that predict CVD risk. METHODS:In a prospective, double-blind, randomized, placebo-controlled trial of 5 smoking cessation pharmacotherapies, symptom-limited TST was performed to determine peak METs, rate-pressure product (RPP), heart rate (HR) increase, HR reserve, and 60-second HR recovery, before and 3 years after the target smoking cessation date. Relationships between TST parameters and treatments among successful abstainers and continuing smokers were evaluated using multivariable analyses. RESULTS:At baseline, the 600 current smokers (61% women) had a mean age of 43.4 (SD 11.5) years and smoked 20.7 (8.4) cigarettes per day. Their exercise capacity was 8.7 (2.3) METs, HR reserve was 86.6 (9.6)%, HR increase was 81.1 (20.9) beats/min, and HR recovery was 22.3 (11.3) beats. Cigarettes per day and pack-years were independently and inversely associated with baseline peak METs (P < .001), RPP (P < .01, pack-years only), HR increase (P < .05), and HR reserve (P < .01). After 3 years, 168 (28%) had quit smoking. Abstainers had greater improvements than continuing smokers (all P < .001) in RPP (2,055 mm Hg beats/min), HR increase (5.9 beats/min), and HR reserve (3.7%), even after statistical adjustment (all P < .001). CONCLUSIONS:Smokers with a higher smoking burden have lower exercise capacity, lower HR reserve, and a blunted exercise HR response. After 3 years, TST improvements suggestive of improved CVD prognosis were observed among successful abstainers.

journal_name

Am Heart J

journal_title

American heart journal

authors

Asthana A,Piper ME,McBride PE,Ward A,Fiore MC,Baker TB,Stein JH

doi

10.1016/j.ahj.2011.06.023

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

81-87.e1

issue

1

eissn

0002-8703

issn

1097-6744

pii

S0002-8703(11)00493-5

journal_volume

163

pub_type

杂志文章,随机对照试验

相关文献

AMERICAN HEART JOURNAL文献大全
  • Fasting glucose levels within the high normal range predict cardiovascular outcome.

    abstract：BACKGROUND:Diabetes mellitus and impaired glucose metabolism are associated with increased risk for cardiovascular disease (CVD). However, it is still not clear whether glucose levels can predict CVD risk among patients without diabetes. The primary aim of this study is to assess whether normoglycemic fasting plasma gl...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2012.03.023

    authors： Shaye K,Amir T,Shlomo S,Yechezkel S

    更新日期：2012-07-01 00:00:00

  • Reduction of neointimal hyperplasia after coronary stenting by pioglitazone in nondiabetic patients with metabolic syndrome.

    abstract：BACKGROUND:This study investigates whether pioglitazone reduces neointimal hyperplasia after coronary stenting in nondiabetic patients with metabolic syndrome (MS) using intravascular ultrasound (IVUS). Pioglitazone, a novel insulin-sensitizing thiazolidinedione, has been shown to reduce neointimal hyperplasia after co...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2007.02.022

    authors： Katayama T,Ueba H,Tsuboi K,Kubo N,Yasu T,Kuroki M,Saito M,Momomura S,Kawakami M

    更新日期：2007-05-01 00:00:00

  • Association between bleeding, blood transfusion, and costs among patients with non-ST-segment elevation acute coronary syndromes.

    abstract：BACKGROUND:Bleeding and blood transfusion are associated with increased morbidity and mortality among patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS); however, the economic consequences of these complications are not well defined. We sought to determine the relationship between bleeding, bloo...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2007.10.014

    authors： Rao SV,Kaul PR,Liao L,Armstrong PW,Ohman EM,Granger CB,Califf RM,Harrington RA,Eisenstein EL,Mark DB

    更新日期：2008-02-01 00:00:00

  • Mode of deployment of coronary Palmaz-Schatz stents after implantation with the stent delivery system: an intravascular ultrasound study.

    abstract：:The stent delivery system (SDS) is a sheath-covered Palmaz-Schatz stent mounted on a 3.0, 3.5, or 4.0 mm compliant polyethylene balloon catheter; the balloon resists maximal inflation pressures of 5.7, 6.2, or 6.0 atm, respectively. It is postulated that these pressures are too low to obtain optimal stent deployment. ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(95)90308-9

    authors： Kiemeneij F,Laarman G,Slagboom T

    更新日期：1995-04-01 00:00:00

  • Sex differences in depression after coronary artery bypass graft surgery.

    abstract：BACKGROUND:Previous research suggests that after coronary artery bypass graft (CABG) surgery, women fare worse than men. This study investigates sex differences in depression during recovery from CABG surgery. METHODS:We followed 137 patients (72 men, 65 women) undergoing elective isolated first CABG surgery between J...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2005.05.005

    authors： Mitchell RH,Robertson E,Harvey PJ,Nolan R,Rodin G,Romans S,Abramson BL,Brister SJ,Ivanov J,Stewart DE

    更新日期：2005-11-01 00:00:00

  • Incidence and clinical outcome of minor surgery in the year after drug-eluting stent implantation: results from the Evaluation of Drug-Eluting Stents and Ischemic Events Registry.

    abstract：BACKGROUND:The aim of the study was to describe the incidence and consequences of minor surgery after drug-eluting stent (DES) implantation. METHODS:The Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) Registry prospectively enrolled unselected patients undergoing percutaneous coronary intervention at 47 ...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ahj.2010.09.028

    authors： Brilakis ES,Cohen DJ,Kleiman NS,Pencina M,Nassif D,Saucedo J,Piana RN,Banerjee S,Keyes MJ,Yen CH,Berger PB

    更新日期：2011-02-01 00:00:00

  • Conduction disturbances of the bundle branches produced by lesions in the nonbranching portion of His bundle.

    abstract：:The present experiments were conducted on isolated dog hearts to demonstrate that conduction disturbances can be induced in the bundle branches by transection of about 50 per cent of the cross-sectional area of the His bundle on the right or left side. The His bundle, the posterior and anterior divisions of left bundl...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(76)80117-2

    authors： Fabregas RA,Tse WW,Han J

    更新日期：1976-09-01 00:00:00

  • Diet and incident venous thromboembolism: the Iowa Women's Health Study.

    abstract：BACKGROUND:Little is known about the role of diet in the development of venous thromboembolism (VTE). We explored the prospective relation of dietary patterns, food groups, and nutrients to incident VTE in older women. METHODS:In 1986, Iowa women aged 55 to 69 years completed a mailed survey, including a 127-item food...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2009.04.003

    authors： Lutsey PL,Steffen LM,Virnig BA,Folsom AR

    更新日期：2009-06-01 00:00:00

  • Treatment of anxiety in patients with coronary heart disease: Rationale and design of the UNderstanding the benefits of exercise and escitalopram in anxious patients WIth coroNary heart Disease (UNWIND) randomized clinical trial.

    abstract：BACKGROUND:Anxiety is highly prevalent among patients with coronary heart disease (CHD), and there is growing evidence that high levels of anxiety are associated with worse prognosis. However, few studies have evaluated the efficacy of treating anxiety in CHD patients for reducing symptoms and improving clinical outcom...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2016.03.003

    authors： Blumenthal JA,Feger BJ,Smith PJ,Watkins LL,Jiang W,Davidson J,Hoffman BM,Ashworth M,Mabe SK,Babyak MA,Kraus WE,Hinderliter A,Sherwood A

    更新日期：2016-06-01 00:00:00

  • Role of intracellular calcium in the antiarrhythmic effect of procainamide during ventricular fibrillation in rat hearts.

    abstract：:Increased intracellular calcium (calcium overload) is considered one of the factors that can initiate ventricular fibrillation. In addition, ventricular fibrillation itself can cause and possibly maintain calcium overload. The goal of this study was to determine whether the class IA antiarrhythmic agent procainamide c...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(95)90453-0

    authors： Zaugg CE,Wu ST,Kojima S,Wikman-Coffelt J,Parmley WW,Buser PT

    更新日期：1995-08-01 00:00:00

  • Study design for the Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care (IMMEDIATE) Trial: A double-blind randomized controlled trial of intravenous glucose, insulin, and potassium for acute coronary syndr

    abstract：BACKGROUND:Experimental studies suggest that metabolic myocardial support by intravenous (IV) glucose, insulin, and potassium (GIK) reduces ischemia-induced arrhythmias, cardiac arrest, mortality, progression from unstable angina pectoris to acute myocardial infarction (AMI), and myocardial infarction size. However, tr...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2012.02.002

    authors： Selker HP,Beshansky JR,Griffith JL,D'Agostino RB,Massaro JM,Udelson JE,Rashba EJ,Ruthazer R,Sheehan PR,Desvigne-Nickens P,Rosenberg YD,Atkins JM,Sayah AJ,Aufderheide TP,Rackley CE,Opie LH,Lambrew CT,Cobb LA,Macleod BA

    更新日期：2012-03-01 00:00:00

  • Can heart failure be prevented, delayed, or reversed?

    abstract：:A review of the clinical course of chronic heart failure demonstrates that current outcomes remain highly unsatisfactory both in mortality and perhaps more important in morbidity. The extraordinary satisfactory functional responses seen in patients who undergo cardiac transplantation clearly identify the primary cause...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/0002-8703(90)90056-4

    authors： Swan HJ

    更新日期：1990-12-01 00:00:00

  • Validation of the accuracy of pretest and exercise test scores in women with a low prevalence of coronary disease: the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE) study.

    abstract：BACKGROUND:Recently revised American College of Cardiology/American Heart Association guidelines have suggested that exercise test scores be used in decisions concerning patients with suspected coronary artery disease (CAD). Pretest and exercise test scores derived for use in women without known CAD have not been teste...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/j.ahj.2003.12.034

    authors： Morise AP,Olson MB,Merz CN,Mankad S,Rogers WJ,Pepine CJ,Reis SE,Sharaf BL,Sopko G,Smith K,Pohost GM,Shaw L

    更新日期：2004-06-01 00:00:00

  • New-onset atrial fibrillation predicts long-term newly developed atrial fibrillation after coronary artery bypass graft.

    abstract：BACKGROUND:New-onset postoperative atrial fibrillation (POAF) is associated with poor short- and long-term outcomes after isolated coronary artery bypass graft (CABG). This study evaluated whether new-onset POAF is independently associated with long-term (>1 year) atrial fibrillation (AF) and mortality. METHODS:Among ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2013.12.010

    authors： Lee SH,Kang DR,Uhm JS,Shim J,Sung JH,Kim JY,Pak HN,Lee MH,Joung B

    更新日期：2014-04-01 00:00:00

  • Serum chromium in patients with recent and old myocardial infarction.

    abstract：:The serum chromium in 45 subjects with no clinical evidence of ischemic heart disease was found to be 1.71 parts per billion (ppb) (S.E. +/- 0.14). In 34 patients with a previously documented myocardial infarction, it was 1.84 ppb (S.E. +/- 0.18). The difference was not significant nor was there any difference with ag...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(80)90734-6

    authors： Abraham AS,Sonnenblick M,Eni M,Shemesh O,Batt AP

    更新日期：1980-05-01 00:00:00

  • Low restenosis rate of the NIR coronary stent: results of the Danish multicenter stent study (DANSTENT)--a randomized trial comparing a first-generation stent with a second-generation stent.

    abstract：BACKGROUND:Larger studies evaluating the angiographic results of second-generation stents are scarce. The objectives of this study were to assess current standards of angiographic and clinical outcomes after implantation of the second-generation stainless steel stent, NIR (Medinol Ltd, Tel Aviv, Israel), and to compare...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1067/mhj.2003.32

    authors： Jørgensen E,Kelbaek H,Helqvist S,Jensen GV,Saunamäki K,Kastrup J,Madsen JK,Kløvgaard L,Thuesen L,Villadsen A,van Weert AW,Reiber JH,Danish multicenter stent study (DANSTENT).

    更新日期：2003-02-01 00:00:00

  • Cardiovascular outcomes are predicted by exercise-stress myocardial perfusion imaging: Impact on death, myocardial infarction, and coronary revascularization procedures.

    abstract：BACKGROUND:The aim of this study was to determine the impact of myocardial perfusion imaging (MPI) on the outcomes of death, myocardial infarction (MI), and late coronary revascularization procedures. METHODS:In patients undergoing exercise-stress MPI (January 1, 2003-March 31, 2007), we determined the impact of summe...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2011.01.019

    authors： Lee DS,Verocai F,Husain M,Al Khdair D,Wang X,Freeman M,Iwanochko RM

    更新日期：2011-05-01 00:00:00

  • Temporal trends and patterns of early clopidogrel use across the spectrum of acute coronary syndromes.

    abstract：BACKGROUND:Randomized trials have established efficacy of clopidogrel in various types of acute coronary syndromes (ACS). The objective of this study was to examine the temporal trends and patterns of early clopidogrel use (within the first 24 hours of hospitalization) across the spectrum of patients with ACS in Canada...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ahj.2009.01.002

    authors： Rao RV,Goodman SG,Yan RT,Spencer FA,Fox KA,DeYoung JP,Rose B,Grondin FR,Gallo R,Gore JM,Yan AT,Canadian Global Registry of Acute Coronary Events (GRACE\/GRACE(2)) Investigators.

    更新日期：2009-04-01 00:00:00

  • Maturational changes in cardiac muscle myosin adenosine triphosphatase activity relative to hemodynamic alterations in newborn lambs.

    abstract：:We performed a chronologic investigation of left (LV) and right (RV) ventricular myosin ATPase activity and hemodynamics in newborn lambs. We found an elevation in myosin ATPase activity for the LV, which was achieved by 6 to 8 weeks of age and which correlated directly with increasing ventricular stroke work. Myosin ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(82)90396-9

    authors： Riemenschneider TA,Brenner RA,Wikman-Coffelt J,Mason DT

    更新日期：1982-05-01 00:00:00

  • Delivering heart failure disease management in 3 tertiary care centers: key clinical components and venues of care.

    abstract：BACKGROUND:Little data exist to assist to help those organizing and managing heart failure (HF) disease management (DM) programs. We aimed to describe the intensity of outpatient HF care (clinic visits and telephone calls) and medical and nonpharmacological interventions in the outpatient setting. METHODS:This was a p...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2007.12.026

    authors： Shah MR,Whellan DJ,Peterson ED,Nohria A,Hasselblad V,Xue Z,Bowers MT,O'Connor CM,Califf RM,Stevenson LW

    更新日期：2008-04-01 00:00:00

  • Integrative noetic therapies as adjuncts to percutaneous intervention during unstable coronary syndromes: Monitoring and Actualization of Noetic Training (MANTRA) feasibility pilot.

    abstract：BACKGROUND:Patients undergoing percutaneous coronary intervention (PCI) for unstable coronary syndromes have substantial emotional and spiritual distress that may promote procedural complications. Noetic (nonpharmacologic) therapies may reduce anxiety, pain and distress, enhance the efficacy of pharmacologic agents, or...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1067/mhj.2001.119138

    authors： Krucoff MW,Crater SW,Green CL,Maas AC,Seskevich JE,Lane JD,Loeffler KA,Morris K,Bashore TM,Koenig HG

    更新日期：2001-11-01 00:00:00

  • Assessment of patent foramen ovale in carcinoid heart disease.

    abstract：BACKGROUND AND OBJECTIVE:Carcinoid syndrome may involve right carcinoid heart disease (CHD), secondary to the release of vasoactive substances. Left CHD is rare, as the inactivation of serotonin by the lung protects the left heart. We attempted to evaluate the prevalence of CHD and patent foramen ovale (PFO) with seria...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2006.02.019

    authors： Mansencal N,Mitry E,Forissier JF,Martin F,Redheuil A,Lepère C,Farcot JC,Joseph T,Lacombe P,Rougier P,Dubourg O

    更新日期：2006-05-01 00:00:00

  • High fasting glucose levels as a predictor of worse clinical outcome in patients with coronary artery disease: results from the Bezafibrate Infarction Prevention (BIP) study.

    abstract：BACKGROUND:A high fasting glucose level may be a marker not only for microvascular complications, but also for macrovascular complications. We evaluated the clinical significance of a high fasting glucose level (> or =110 mg/dL), detected either at baseline or during follow-up, in the Bezafibrate Infarction Prevention ...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.ahj.2003.09.013

    authors： Arcavi L,Behar S,Caspi A,Reshef N,Boyko V,Knobler H

    更新日期：2004-02-01 00:00:00

  • Hemodynamic effects of alinidine (ST 567) at rest and during exercise in patients with chronic congestive heart failure.

    abstract：:Selective inhibition of sinus node function offers the possibility to decrease heart rate and reduce myocardial oxygen consumption in patients with impaired cardiac function, if myocardial contractility is not further attenuated. To study the influence of a specific sinus node inhibitor on myocardial function, alinidi...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(05)80185-1

    authors： Koenig W,Stauch M,Sund M,Wanjura D,Henze E

    更新日期：1990-06-01 00:00:00

  • Systemic and renal hemodynamic effects of bupicomide: a new vasodilator.

    abstract：:The systemic and renal hemodyanmic effects of bupicomide were studied in 10 male patients with uncomplicated essential hypertension of moderate severity. Bupicomide significantly reduced systolic, diastolic, and mean arterial pressure and peripheral vascular resistance and this hypotensive effect was associated with a...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0002-8703(76)80114-7

    authors： Chrysant SG,Adamopoulos P,Tsuchiya M,Frohlich ED

    更新日期：1976-09-01 00:00:00

  • Successful left ventricular opacification following peripheral venous injection of sonicated contrast agent: an experimental evaluation.

    abstract：:A new agent for use in contrast echocardiography that is capable of passing through the pulmonary circulation and opacifying the left ventricular cavity after intravenous injection was evaluated in a canine model. Air-filled albumin microbubbles were produced by sonication. A Coulter counter was used to size and count...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(87)90754-x

    authors： Keller MW,Feinstein SB,Watson DD

    更新日期：1987-09-01 00:00:00

  • Impact of contrast-induced acute kidney injury definition on clinical outcomes.

    abstract：BACKGROUND:Contrast-induced acute kidney injury (CIAKI) is a frequent complication after infusion of contrast media in patients undergoing percutaneous coronary intervention. A wide range of CIAKI rates occurs after intervention between 3% and 30%, depending on the definition. The aim of this study was to identify whic...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2011.02.004

    authors： Budano C,Levis M,D'Amico M,Usmiani T,Fava A,Sbarra P,Burdese M,Segoloni GP,Colombo A,Marra S

    更新日期：2011-05-01 00:00:00

  • An integrated approach to diagnosis and therapeutic management of patients with systolic heart failure in the Copenhagen metropolitan area.

    abstract：BACKGROUND:Studies on the effect of heart failure clinics have been encouraging and convincing with respect to reduced hospitalizations, improved quality of life, and reduced cost. However, previous results have been derived from patient populations either recently discharged and with specific exclusion criteria or fro...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1067/mhj.2002.123841

    authors： Galatius S,Gustafsson F,Nielsen PH,Atar D,Hildebrandt PR

    更新日期：2002-08-01 00:00:00

  • Adenosine in myocardial perfusion imaging using positron emission tomography.

    abstract：:Because of its unique ability to demonstrate the metabolic consequences of myocardial ischemia, positron emission tomography (PET) is extremely valuable in assessing myocardial viability. PET imaging can identify the myocardial segments that are likely to improve after revascularization and may be more sensitive and s...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/0002-8703(91)90803-p

    authors： Gupta NC,Esterbrooks D,Mohiuddin S,Hilleman D,Sunderland J,Shiue CY,Frick MP

    更新日期：1991-07-01 00:00:00

  • Postoperative abnormalities of interventricular septal motion: two-dimensional and M-mode echocardiographic correlations.

    abstract：:Our hypothesis was that the postoperative abnormalities in septal motion observed by M-mode echocardiography (MME) are due to changes of either ventricular shape or of total cardiac motion within the thorax. We obtained preoperative and early and late postoperative MME and two-dimensional echocardiograms on 25 patient...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(82)90202-2

    authors： Kerber RE,Litchfield R

    更新日期：1982-08-01 00:00:00