当前位置： SCI文献检索 > AMERICAN HEART JOURNAL期刊下所有文献 > Can heart failure be prevented, delayed, or reversed?

Can heart failure be prevented, delayed, or reversed?

Abstract：

:A review of the clinical course of chronic heart failure demonstrates that current outcomes remain highly unsatisfactory both in mortality and perhaps more important in morbidity. The extraordinary satisfactory functional responses seen in patients who undergo cardiac transplantation clearly identify the primary cause as the status of the heart itself, whatever the pathophysiologic adjustments of the neuroendocrine system, and interventions of the wide variety of drugs. Since donor hearts are unlikely to be available even from younger sufferers of these clinical syndromes, prevention must be the hallmark. Protection of the viability of myocytes, such as in acute myocarditis and acute infarction, is essential. Myocardial collagen undergoes continual synthesis, and production is greatly stimulated in the presence of hypertrophy caused by increased wall stress. It is possible that excess collagen is intimately involved with diastolic ventricular dysfunction, but that this may be a reversible process if the collagen-producing stimulus is removed. Thus reduction in wall stress and reversibility of ventricular hypertrophy appear to be promising directions. However, to limit the catastrophic effects of chronic heart failure, early recognition of the precursors of these syndromes, prevention of progression, and surgical intervention in valvular heart disease at an optimal point in time are essential.

journal_name

Am Heart J

journal_title

American heart journal

authors

Swan HJ

doi

10.1016/0002-8703(90)90056-4

subject

Has Abstract

pub_date

1990-12-01 00:00:00

pages

1540-6

issue

6 Pt 2

eissn

0002-8703

issn

1097-6744

pii

0002-8703(90)90056-4

journal_volume

120

pub_type

杂志文章,评审

相关文献

AMERICAN HEART JOURNAL文献大全
  • Predictors of surgical mortality and long-term results of endocardial resection for drug-refractory ventricular tachycardia.

    abstract：:The results of surgical therapy performed in 51 consecutive patients with ventricular tachycardia were reviewed to determine short- and long-term predictors of success of such therapy in preventing recurrences of life-threatening ventricular arrhythmias. Of 41 patients (80%) who survived surgery, 40 had postoperative ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(92)90404-j

    authors： Mittleman RS,Candinas R,Dahlberg S,Vander Salm T,Moran JM,Huang SK

    更新日期：1992-11-01 00:00:00

  • Safety and efficacy of femoral vascular closure devices in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction.

    abstract：BACKGROUND:The use of vascular closure devices (VCDs) for the reduction of access site complications following percutaneous coronary intervention (PCI) remains controversial. Patients undergoing primary PCI for acute ST-segment elevation myocardial infarction (STEMI) are at high risk of femoral artery complications. A ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2011.03.009

    authors： Prada-Delgado Ó,Estévez-Loureiro R,Calviño-Santos R,Barge-Caballero E,Salgado-Fernández J,Piñón-Esteban P,Vázquez-Rodríguez JM,Aldama-López G,Flores-Ríos X,Soler-Martín MR,Vázquez-González N,Castro-Beiras A

    更新日期：2011-06-01 00:00:00

  • A comparison of standard and high-dose regimens for the initiation of amiodarone therapy.

    abstract：:The effects of two regimens for the initiation of amiodarone therapy were compared in 92 patients with inducible sustained ventricular tachycardia (VT) at baseline electrophysiologic testing. Two groups of 46 patients each received a total of 16.8 gm of oral amiodarone before follow-up electrophysiologic testing. Grou...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章

    doi：10.1016/0002-8703(92)90599-q

    authors： Summitt J,Morady F,Kadish A

    更新日期：1992-08-01 00:00:00

  • Tachyarrhythmias associated with programmable automatic atrial antitachycardia pacemakers.

    abstract：:A multiprogrammable automatic antitachycardia pacemaker (Cybertach-60), connected to a tined "J" wire electrode, was positioned in the right atrial appendage in three patients with recurrent supraventricular tachycardia (SVT). Mechanisms of SVT included atrioventricular (AV) nodal reentry (two patients) and reciprocat...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(83)90648-8

    authors： Lerman BB,Waxman HL,Buxton AE,Sweeney M,Josephson ME

    更新日期：1983-11-01 00:00:00

  • Intravascular and extravascular pulmonary fluid volumes during chronic experimental left ventricular dysfunction.

    abstract：:To assess the effects of chronic left ventricular (LV) dysfunction on intravascular pulmonary blood volume (PBV) and extravascular lung water (EVLW) lung fluid volumes, 56 dogs were evaluated by means of double-indicator dilution techniques. PBV and EVLW were measured in seven control dogs, in eight dogs 4 hours after...

    journal_title：American heart journal

    pub_type： 杂志文章,收录出版

    doi：10.1016/0002-8703(84)90421-6

    authors： Slutsky RA,Olson LK

    更新日期：1984-09-01 00:00:00

  • Long-term outcomes of arrhythmia and distinct electrophysiological features in congenitally corrected transposition of the great arteries in an Asian cohort.

    abstract：:Congenitally corrected transposition of the great arteries (ccTGA) is associated with various types of arrhythmia, including supraventricular tachycardia (SVT) and complete atrioventricular block (cAVB). Our study aims to characterize the arrhythmia burden, associated risk factors, arrhythmia mechanisms, and the long-...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2020.10.057

    authors： Tseng WC,Huang CN,Chiu SN,Lu CW,Wang JK,Lin MT,Chen CA,Wu MH

    更新日期：2021-01-01 00:00:00

  • Relation of fibrinogen to cardiovascular events is independent of preclinical cardiovascular disease: the Strong Heart Study.

    abstract：BACKGROUND:It is unclear whether fibrinogen predicts cardiovascular events independently of echocardiographic cardiovascular abnormalities and traditional risk factors. METHODS:We studied 2671 American Indians who participated in the second Strong Heart Study examination (1993-1995) and were observed for an average of...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1067/mhj.2003.144

    authors： Palmieri V,Celentano A,Roman MJ,de Simone G,Best L,Lewis MR,Robbins DC,Fabsitz RR,Howard BV,Devereux RB,Strong Heart Study.

    更新日期：2003-03-01 00:00:00

  • Implications of inferior ST-segment depression in anterior acute myocardial infarction: electrocardiographic and angiographic correlation.

    abstract：:This study assesses the significance of inferior ST-segment depression during anterior acute myocardial infarction (AMI) by investigating the relationship between inferior ST-segment depression and (1) the site of the left anterior descending (LAD) coronary artery lesion and (2) ST-segment deviation in the various ant...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(94)90372-7

    authors： Birnbaum Y,Solodky A,Herz I,Kusniec J,Rechavia E,Sulkes J,Sclarovsky S

    更新日期：1994-06-01 00:00:00

  • Bradycardia and hypotension following reperfusion with streptokinase (Bezold-Jarisch reflex): a sign of coronary thrombolysis and myocardial salvage.

    abstract：:Acute myocardial infarction, particularly of the inferior wall, is frequently associated with bradycardia and hypotension. This study reports the occurrence of transient bradycardia hypotension (TBH) (Bezold-Jarisch reflex) following thrombolytic therapy with intravenous streptokinase. Of the 52 patients, 42 had succe...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(86)90508-9

    authors： Koren G,Weiss AT,Ben-David Y,Hasin Y,Luria MH,Gotsman MS

    更新日期：1986-09-01 00:00:00

  • Effect of probucol in hyperlipidemic patients during two years of administration.

    abstract：:Probucol, a new cholesterol-lowering agent, was administered to ambulatory outpatients representing several classes of hyperlipoproteinemia (HL) for two years without dietary restriction. In 32 patients with Type II HL and 12 with Type IIB HL, statistically significant reduction in mean serum cholesterol levels occurr...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章

    doi：10.1016/0002-8703(78)90088-1

    authors： Parsons WB Jr

    更新日期：1978-08-01 00:00:00

  • The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chr

    abstract：OBJECTIVES:The DANHEART trial is a multicenter, randomized (1:1), parallel-group, double-blind, placebo-controlled study in chronic heart failure patients with reduced ejection fraction (HFrEF). This investigator driven study will include 1500 HFrEF patients and test in a 2 × 2 factorial design: 1) if hydralazine-isoso...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2020.09.020

    authors： Wiggers H,Køber L,Gislason G,Schou M,Poulsen MK,Vraa S,Nielsen OW,Bruun NE,Nørrelund H,Hollingdal M,Barasa A,Bøttcher M,Dodt K,Hansen VB,Nielsen G,Knudsen AS,Lomholdt J,Mikkelsen KV,Jonczy B,Brønnum-Schou J,Poenar

    更新日期：2021-01-01 00:00:00

  • Pulmonary function in hypertensive patients treated with pindolol: a report of two studies.

    abstract：:Pulmonary function was measured serially in two separate randomized trials of pindolol in the treatment of essential hypertension. Patients with overt obstructive airways disease were excluded. In study 1, 131 hypertensive patients were randomized to placebo (31) and 15 mg (33), 30 mg (33), and 60 mg (34) of pindolol....

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-8703(82)90135-1

    authors： Hamilton BP,Hamilton J,Kirkendall WM

    更新日期：1982-08-01 00:00:00

  • Diagnostic value of 12-lead electrocardiogram during dobutamine echocardiographic studies.

    abstract：BACKGROUND:The diagnostic value of 12-lead electrocardiography during dobutamine stress echocardiography (DSE) is not well documented. METHODS AND RESULTS:We reviewed the records of 116 patients referred for DSE and coronary angiography, 52 of whom were excluded because of abnormal ST segment or inadequate DSE. Of the...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(98)70163-2

    authors： Shaheen J,Luria D,Klutstein MW,Rosenmann D,Tzivoni D

    更新日期：1998-12-01 00:00:00

  • Diet and incident venous thromboembolism: the Iowa Women's Health Study.

    abstract：BACKGROUND:Little is known about the role of diet in the development of venous thromboembolism (VTE). We explored the prospective relation of dietary patterns, food groups, and nutrients to incident VTE in older women. METHODS:In 1986, Iowa women aged 55 to 69 years completed a mailed survey, including a 127-item food...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2009.04.003

    authors： Lutsey PL,Steffen LM,Virnig BA,Folsom AR

    更新日期：2009-06-01 00:00:00

  • Relationships among clinic, home, and ambulatory blood pressures with small vessel disease of the brain and functional status in older people with hypertension.

    abstract：BACKGROUND:Subcortical small vessel disease, represented as white matter hyperintensity (WMH) on magnetic resonance images (MRI) is associated with functional decline in older people with hypertension. We evaluated the relationships of clinic and out-of-office blood pressures (BP) with WMH and functional status in olde...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.ahj.2018.08.002

    authors： White WB,Jalil F,Wakefield DB,Kaplan RF,Bohannon RW,Hall CB,Moscufo N,Fellows D,Guttmann CRG,Wolfson L

    更新日期：2018-11-01 00:00:00

  • Efficacy of prolonged infusion of urodilatin [ANP-(95-126)] in patients with congestive heart failure.

    abstract：:Urodilatin [ANP-95-126] is a new natriuretic peptide of renal origin not subjected to tolerance in experimental congestive heart failure (CHF). To evaluate its therapeutic potentials in CHF, we investigated the efficacy of a prolonged infusion of urodilatin (15 ng/kg/min for 10 hours) in 12 patients with CHF (New York...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-8703(95)90328-3

    authors： Elsner D,Muders F,Müntze A,Kromer EP,Forssmann WG,Riegger GA

    更新日期：1995-04-01 00:00:00

  • Left ventricular ejection fraction to predict early mortality in patients with non-ST-segment elevation acute coronary syndromes.

    abstract：BACKGROUND:Improvement in risk stratification of patients with non-ST-segment elevation acute coronary syndrome (ACS) is a gateway to a more judicious treatment. This study examines whether the routine determination of left ventricular ejection fraction (EF) adds significant prognostic information to currently recommen...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ahj.2004.09.027

    authors： Bosch X,Théroux P

    更新日期：2005-08-01 00:00:00

  • Dependency of premature ventricular contractions on heart rate.

    abstract：:To identify a method for characterizing the dynamic behavior of ventricular arrhythmias at different heart rates, 201 consecutive patients with frequent premature ventricular contractions (PVCs) underwent two 24-hour electrocardiographic monitoring periods. The percentage of PVCs for each cycle length was calculated a...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(97)70203-5

    authors： Pitzalis MV,Mastropasqua F,Massari F,Passantino A,Forleo C,Luzzi G,Totaro P,De Nicolò M,Rizzon P

    更新日期：1997-02-01 00:00:00

  • Baseline characteristics of patients in the coronary artery bypass graft (CABG) Patch Trial.

    abstract：BACKGROUND:Patients with left ventricular dysfunction who undergo coronary artery bypass graft (CABG) surgery frequently have late sudden cardiac death. The CABG Patch Trial is a prospective, randomized, multicenter clinical trial that randomized patients at high risk at the completion of CABG surgery to implantation o...

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0002-8703(97)80001-4

    authors： Curtis AB,Cannom DS,Bigger JT Jr,DiMarco JP,Estes NA 3rd,Steinman RC,Parides MK

    更新日期：1997-11-01 00:00:00

  • New phenotype of familial dilated cardiomyopathy and conduction disorders.

    abstract：BACKGROUND:Familial dilated cardiomyopathy (FDCM) is attributed to defects in cytoskeletal proteins, and different patterns of inheritance and phenotypic expressions according to assorted-protein modifications have been identified to date. We describe a clinical family study with 24 individuals in 3 generations affecte...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1067/mhj.2003.141

    authors： Oropeza ES,Cadena CN

    更新日期：2003-02-01 00:00:00

  • Selection criteria for placement of left ventricular assist devices.

    abstract：:The 2,000 heart donors available annually continue to be inadequate for the 50,000 patients with end-stage congestive heart failure who require heart transplantation to survive. This discrepancy has led to the successful use of long-term implantable LVADs as a bridge to transplantation and has raised the issue of perm...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(95)90056-x

    authors： Oz MC,Rose EA,Levin HR

    更新日期：1995-01-01 00:00:00

  • Hemodynamic effects of molsidomine in patients with heart failure following acute myocardial infarction.

    abstract：:The short-term hemodynamic effects of molsidomine (4 mg sublingually) were evaluated in 13 patients with congestive heart failure following acute myocardial infarction. Right heart catheterization was performed by means of a Swan-Ganz thermodilution catheter. Hemodynamic measurements were made 30, 60, 120, and 180 min...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：

    authors： Cantelli I,Lolli C,Brunelli A,Bracchetti D

    更新日期：1985-03-01 00:00:00

  • Pathophysiologic significance of free and conjugated dopamines in congestive heart failure.

    abstract：:sulfoconjugated dopamine constitutes the major portion of circulating or excreted dopamine, but its physiologic significance is still unknown. To test whether conjugated dopamine serves as a source of free dopamine in response to acute stress, plasma concentrations of free and conjugated dopamine were measured during ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(94)90671-8

    authors： Nakaya Y,Katayama T,Nomura M,Ishimura Y,Ohuchi T,Oka M,Yamamoto M,Mizobuchi S

    更新日期：1994-03-01 00:00:00

  • Noninvasive evaluation of right ventricular and pulmonary artery systolic pressures in patients with ventricular septal defects: simultaneous study of Doppler and catheterization data.

    abstract：:The method for evaluating right ventricular and pulmonary artery systolic pressures by subtracting the systolic pressure gradient across the ventricular septal defect from the cuff systolic blood pressure is documented. To confirm the reliability and accuracy of this method, simultaneous continuous wave Doppler echoca...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(93)90116-q

    authors： Ge Z,Zhang Y,Kang W,Fan D,Ji X,Duran C

    更新日期：1993-04-01 00:00:00

  • Pulmonary valve annulus grows after balloon dilatation of neonatal critical pulmonary valve stenosis.

    abstract：BACKGROUND:Neonates with critical pulmonary valve stenosis often demonstrate small or hypoplastic right ventricular structures. Relief of the obstruction enhances forward flow across the right ventricle and reduces its pressure load. Growth of the right ventricle and especially of the pulmonary valve annulus was evalua...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1053/hj.1998.v136.89576

    authors： Gildein HP,Kleinert S,Goh TH,Wilkinson JL

    更新日期：1998-08-01 00:00:00

  • Rationale and design of the Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation (ARTESiA) trial.

    abstract：BACKGROUND:Device-detected subclinical atrial fibrillation (AF) refers to infrequent, short-lasting, asymptomatic AF that is detected only with long-term continuous monitoring. Subclinical AF is common and associated with an increased risk of stroke; however, the risk of stroke with subclinical AF is lower than for cli...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2017.04.008

    authors： Lopes RD,Alings M,Connolly SJ,Beresh H,Granger CB,Mazuecos JB,Boriani G,Nielsen JC,Conen D,Hohnloser SH,Mairesse GH,Mabo P,Camm AJ,Healey JS

    更新日期：2017-07-01 00:00:00

  • Pharmacologic characteristics of a new calcium antagonist, manidipine: beneficial effects on renal circulation and vascular changes.

    abstract：:The calcium antagonist, manidipine, was developed on the basis of the hypothesis that antihypertensive drugs that act to improve renal hemodynamic alterations will be therapeutically beneficial in hypertensive patients. Manidipine shows long-lasting calcium channel-blocking action in vascular smooth muscle cells and a...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/0002-8703(93)90203-l

    authors： Nagaoka A

    更新日期：1993-02-01 00:00:00

  • Long-term economic outcomes associated with intensive versus moderate lipid-lowering therapy in coronary artery disease: results from the Treating to New Targets (TNT) Trial.

    abstract：BACKGROUND:In 10,001 patients with stable coronary artery disease (CAD) enrolled in the Treating to New Targets (TNT) trial, 80 mg/d of atorvastatin (high-dose regimen) reduced the composite primary end point of death from CAD, nonfatal myocardial infarction, resuscitation from cardiac arrest, or stroke by 22% relative...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2008.05.032

    authors： Mark DB,Knight JD,Cowper PA,Davidson-Ray L,Anstrom KJ

    更新日期：2008-10-01 00:00:00

  • Mitral valve prolapse in anxiety neurosis (panic disorder).

    abstract：:Our purpose was to determine the incidence of mitral valve prolapse in patients with anxiety neurosis or panic disorder, with symptoms including recurrent anxiety attacks, dyspnea, palpitations, chest pain, dizziness, and paresthesias. Twenty-one patients and 20 age- and sex-matched normal controls were studied. Objec...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(80)90142-8

    authors： Venkatesh A,Pauls DL,Crowe R,Noyes R Jr,Van Valkenburg C,Martins JB,Kerber RE

    更新日期：1980-09-01 00:00:00

  • Outcomes after STEMI in old multimorbid patients with complex health needs and the effect of invasive management.

    abstract：BACKGROUND:The aim of this study was to assess one-year outcomes of invasive and non-invasive strategies in ST-elevation myocardial infarction (STEMI) among multimorbid older people with complex health needs. METHODS:We included patients, registered between 2006 and 2013 in the SWEDEHEART registry, who were 70 years o...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2019.01.008

    authors： Gudnadottir GS,James SK,Andersen K,Lagerqvist B,Thrainsdottir IS,Ravn-Fischer A,Varenhorst C,Gudnason T

    更新日期：2019-05-01 00:00:00