Implications of inferior ST-segment depression in anterior acute myocardial infarction: electrocardiographic and angiographic correlation.

Abstract:

:This study assesses the significance of inferior ST-segment depression during anterior acute myocardial infarction (AMI) by investigating the relationship between inferior ST-segment depression and (1) the site of the left anterior descending (LAD) coronary artery lesion and (2) ST-segment deviation in the various anterior and lateral leads. We studied 126 patients with anterior AMI who underwent coronary angiography within 21 days of hospitalization. The admission 12-lead electrocardiograms were evaluated for ST-segment amplitude in each lead at 0.08 second after the J-point. Coronary angiography was evaluated for the site and severity of luminal narrowing of the coronary arteries. The site of the culprit lesion in the LAD artery, relative to the origin of the first septal and diagonal branches, was determined. In four patients no lesion was identified in the LAD artery. Of the remaining 122 patients, 40 and 53 patients had a LAD artery lesion proximal to the first septal and first diagonal branches, respectively. Additional luminal narrowing (> or = 70% of diameter) was found in the circumflex and the right coronary arteries in 27 and 37 patients, respectively. ST-segment depression of > 1 mm in leads II, III, and aVF was noted in 24, 29, and 24 patients, respectively. The prevalence of a LAD artery preseptal and prediagonal lesion was higher in patients with inferior ST-segment depression.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

Am Heart J

journal_title

American heart journal

authors

Birnbaum Y,Solodky A,Herz I,Kusniec J,Rechavia E,Sulkes J,Sclarovsky S

doi

10.1016/0002-8703(94)90372-7

subject

Has Abstract

pub_date

1994-06-01 00:00:00

pages

1467-73

issue

6

eissn

0002-8703

issn

1097-6744

pii

0002-8703(94)90372-7

journal_volume

127

pub_type

杂志文章
  • Hyponatremia in patients treated with lorcainide, a new antiarrhythmic drug.

    abstract::The effects of lorcainide, a new antiarrhythmic drug, on serum electrolytes and osmolality are described in a series of 33 patients with organic heart disease and complex ventricular arrhythmias treated with lorcainide. In eight patients, a mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L was observed after a single 2...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(84)90690-2

    authors: Somani P,Temesy-Armos PN,Leighton RF,Goodenday LS,Fraker TD Jr

    更新日期:1984-12-01 00:00:00

  • Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance: rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial.

    abstract::Patients with impaired glucose tolerance (IGT) have increased risk for developing type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Lifestyle modification and medication can prevent or delay progression to diabetes (PD), but whether such interventions also reduce the risk of CVD has not been rigorously...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2008.05.017

    authors: Califf RM,Boolell M,Haffner SM,Bethel M,McMurray J,Duggal A,Holman RR,NAVIGATOR Study Group.

    更新日期:2008-10-01 00:00:00

  • Does ST resolution achieved via different reperfusion strategies (fibrinolysis vs percutaneous coronary intervention) have different prognostic meaning in ST-elevation myocardial infarction? A systematic review.

    abstract:OBJECTIVE:We perform a systematic review to discern if ST resolution achieved via percutaneous coronary intervention (PCI) has a different meaning to that achieved via fibrinolysis. BACKGROUND:Resolution of ST-segment elevation in acute myocardial infarction has been widely used as a surrogate for treatment success. A...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ahj.2010.06.050

    authors: Wong CK,de la Barra SL,Herbison P

    更新日期:2010-11-01 00:00:00

  • Precordial ST-segment mapping 3. Stability of maps in the early phase of acute myocardial infarction.

    abstract::To evaluate the stability of precordial ST-segment mapping techniques in assessing ischemic myocardial injury, we studied 28 patients with acute anterior myocardial infarction using a 49-lead electrocardiographic system (1 mV. = 10 mm.). The sum of ST elevations in millimeters was taken as an index of ischemic injury,...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(77)80011-2

    authors: Madias JE,Hood WB Jr

    更新日期:1977-05-01 00:00:00

  • Efficacy of oral angiotensin-converting enzyme inhibition with captopril therapy in severe chronic normotensive congestive heart failure.

    abstract::To evaluate the therapeutic efficacy of oral angiotensin-converting inhibition (ACE) with captopril in chronic normotensive congestive heart failure (CHF), acute and cardiocirculatory actions were determined by cardiac catheterization and forearm plethysmography, and ambulatory effects were assessed by echocardiograph...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(81)90379-3

    authors: Awan NA,Evenson MK,Needham KE,Win A,Mason DT

    更新日期:1981-01-01 00:00:00

  • Analysis of pulmonary venous flow velocity patterns in hypertensive hearts: its complementary value in the interpretation of mitral flow velocity patterns.

    abstract::Although the Doppler mitral flow velocity pattern changes in accordance with the degree of left ventricular diastolic dysfunction, it is "normalized" in the presence of heart failure. In this study the pulmonary venous flow velocity pattern was characterized in 43 hypertensive patients with and without heart failure t...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(92)90982-2

    authors: Masuyama T,Lee JM,Yamamoto K,Tanouchi J,Hori M,Kamada T

    更新日期:1992-10-01 00:00:00

  • Hemodynamic evaluation by M-mode echocardiography in acute myocardial infarction.

    abstract::We assessed the relationship between echocardiographic and hemodynamic parameters in 28 patients with documented acute myocardial infarction (AMI), who underwent M-mode echocardiography and Swan-Ganz catheterization during the same hospitalization. Patients with valvular heart disease were excluded from the study. On ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(84)90542-8

    authors: Nador F,De Martini M,Binda A,Radrizzani D,Cirò E,Lotto A

    更新日期:1984-07-01 00:00:00

  • Balloon angioplasty of the aorta in Takayasu's arteritis: initial and long-term results.

    abstract::Percutaneous transluminal balloon angioplasty for stenosis of the aorta was performed in 36 patients with Takayasu's arteritis (age range, 8 to 36 years; mean, 19.1 +/- 7.7 years). Balloon dilatation was successful in 34 patients and resulted in a decrease in the mean peak systolic pressure gradient (PSG) from 75.2 +/...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(92)90967-z

    authors: Tyagi S,Kaul UA,Nair M,Sethi KK,Arora R,Khalilullah M

    更新日期:1992-10-01 00:00:00

  • Early and late outcome following deployment of a new flexible tantalum intracoronary stent in dogs.

    abstract::A new radiopaque, highly flexible balloon-expandable tantalum stent was tested. Thirty-six of 40 stents were successfully deployed percutaneously in the coronary arteries of 31 dogs. The dogs were given aspirin before, intravenous heparin during, and aspirin alone after the procedure. One dog died at 24 hours because ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(92)90992-5

    authors: Muhlestein JB,Phillips HR,Quigley PJ,Bauman RP,Gammon RS,Chapman GD,Mikat EM,Palmos LE,Overman AB,Stack RS

    更新日期:1992-10-01 00:00:00

  • Changes in the QRS complex and ST segment in transmural and subendocardial myocardial infarctions. A clinicopathologic study.

    abstract::The QRS complex and ST segment in the ECGs of 80 patients who died of an acute myocardial infarction (MI) were studied in relation to the extent of the MI (subendocardial vs. transmural). Changes in the QRS complex developed in nine out of the 15 cases with an acute subendocardial MI. Five of these cases fulfilled the...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(79)90219-9

    authors: Raunio H,Rissanen V,Romppanen T,Jokinen Y,Rehnberg S,Helin M,Pyörälä K

    更新日期:1979-08-01 00:00:00

  • Correlation of "critical" left coronary artery lesions with positive submaximal exercise tests in patients with chest pain.

    abstract::This study correlates the anatomic pathologic coronary anatomy found by arteriography in each of three groups of symptomatic patients, all with coronary artery disease, divided according to the magnitude of ST-segment depression after an adequate submaximal treadmill exercise test. Group I consists of 45 patients with...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(75)90080-0

    authors: Cheitlin MD,Davia JE,de Castro CM,Barrow EA,Anderson WT

    更新日期:1975-03-01 00:00:00

  • The effect of Aliskiren on exercise capacity in older patients with heart failure and preserved ejection fraction: A randomized, placebo-controlled, double-blind trial.

    abstract::In older patients (70 ± 7 years) with chronic well-compensated heart failure with preserved ejection and controlled blood pressure, 6 months treatment with aliskiren (direct renin inhibitor) showed non-significant trends for modest improvements in peak exercise oxygen consumption (14.9 ± 0.2 mL kg-1 min-1 versus 14.4 ...

    journal_title:American heart journal

    pub_type: 信件

    doi:10.1016/j.ahj.2018.03.019

    authors: Upadhya B,Brubaker PH,Morgan TM,Eggebeen JD,Jao GT,Stewart KP,Kitzman DW

    更新日期:2018-07-01 00:00:00

  • Combination of B-type natriuretic peptide and peak oxygen consumption improves risk stratification in outpatients with chronic heart failure.

    abstract:BACKGROUND:Peak oxygen consumption is a cornerstone for prognostic determination in patients with congestive heart failure. The purpose of this study was to assess whether plasma B-type natriuretic peptide (BNP) provided any additional prognostic information. METHODS:Plasma concentrations of atrial natriuretic peptide...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/S0002-8703(03)00365-X

    authors: Isnard R,Pousset F,Chafirovskaïa O,Carayon A,Hulot JS,Thomas D,Komajda M

    更新日期:2003-10-01 00:00:00

  • The CSL112-2001 trial: Safety and tolerability of multiple doses of CSL112 (apolipoprotein A-I [human]), an intravenous formulation of plasma-derived apolipoprotein A-I, among subjects with moderate renal impairment after acute myocardial infarction.

    abstract:BACKGROUND:CSL112 (apolipoprotein A-I [human]) is a plasma-derived apolipoprotein A-I developed for early reduction of cardiovascular risk following an acute myocardial infarction (AMI). The safety of CSL112 among AMI subjects with moderate, stage 3 chronic kidney disease (CKD) is unknown. METHODS:CSL112_2001, a multi...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2018.11.008

    authors: Gibson CM,Kerneis M,Yee MK,Daaboul Y,Korjian S,Mehr AP,Tricoci P,Alexander JH,Kastelein JJP,Mehran R,Bode C,Lewis BS,Mehta R,Duffy D,Feaster J,Halabi M,Angiolillo DJ,Duerschmied D,Ophuis TO,Merkely B

    更新日期:2019-02-01 00:00:00

  • Sudden death and silent myocardial ischemia.

    abstract::Recent research indicates that silent myocardial ischemia may play a role in sudden cardiac death. To what extent treatment can reduce occurrence of silent ischemia remains to be assessed. Three classes of silent ischemia patients are identified: type 1--totally asymptomatic; type 2--post myocardial infarction; and ty...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(89)90673-x

    authors: Sheps DS,Heiss G

    更新日期:1989-01-01 00:00:00

  • Microwave ablation of canine atrial tachycardia induced by aconitine.

    abstract::We tested the efficacy of microwave-frequency energy for ablating atrial tachycardia in eight open-chest dogs. Five other dogs served as controls. Atrial tachycardia was induced by direct application of aconitine crystals to the epicardial atrial surface or by injection of aconitine solution (0.15 mg/ml) into the righ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(95)90126-4

    authors: Rho TH,Ito M,Pride HP,Waller B,Zipes DP

    更新日期:1995-05-01 00:00:00

  • Correlates of resting and maximal exercise systolic blood pressure after repair of coarctation of the aorta: a multivariable analysis.

    abstract::Repair of coarctation of the aorta may not prevent the subsequent development of elevated systemic blood pressure at rest or with exercise. The correlates of late postoperative resting systolic blood pressure and maximal exercise systolic blood pressure levels were investigated in a retrospective study of 42 patients ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(87)90277-8

    authors: Daniels SR,James FW,Loggie JM,Kaplan S

    更新日期:1987-02-01 00:00:00

  • Use of intensive lipid-lowering therapy in patients hospitalized with acute coronary syndrome: An analysis of 65,396 hospitalizations from 344 hospita participating in Get With The Guidelines (GWTG).

    abstract:OBJECTIVES:The study aimed to analyze the use of intensive lipid-lowering therapy (I-LLT) at discharge in a broad population of patients hospitalized with acute coronary syndrome (ACS). BACKGROUND:Early and intensive statin therapy in ACS has been shown to reduce cardiovascular morbidity and mortality. Utilization and...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2010.12.014

    authors: Javed U,Deedwania PC,Bhatt DL,Cannon CP,Dai D,Hernandez A,Peterson ED,Fonarow GC

    更新日期:2011-02-01 00:00:00

  • Physiologic responses to epinephrine infusion: the basis for a new stress test for coronary artery disease.

    abstract::Since many patients with chest pain cannot exercise adequately, an alternative stress would be useful to evaluate coronary reserve. We studied the physiologic responses to epinephrine to assess its potential. We report on 39 patients with chest pain. Doses from 0.03 to 0.30 micrograms/kg/min were administered intraven...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(83)90477-5

    authors: Schechter E,Wilson MF,Kong YS

    更新日期:1983-04-01 00:00:00

  • Right ventricular myocardial infarction with anterior wall left ventricular infarction: an autopsy study.

    abstract::Right ventricular myocardial infarction has been reported to occur exclusively in association with inferior left ventricular infarction. To determine the frequency of right ventricular myocardial infarction in association with anterior left ventricular myocardial infarction, all hearts with anterior myocardial infarct...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(87)90004-4

    authors: Cabin HS,Clubb KS,Wackers FJ,Zaret BL

    更新日期:1987-01-01 00:00:00

  • Effect of thromboxane synthetase inhibition on vulnerability to ventricular arrhythmia following coronary occlusion.

    abstract::Release of thromboxane (TXA2) during acute myocardial infarction may be an important contributing factor in the genesis of ventricular fibrillation (VF). We assessed the effect of selective TXA2 inhibition on vulnerability to VF after total occlusion of the anterior descending coronary artery in chloralose-anesthetize...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(86)90099-2

    authors: O'Connor KM,Friehling TD,Kelliher GJ,MacNab MW,Wetstein L,Kowey PR

    更新日期:1986-04-01 00:00:00

  • Exercise-induced alterations of signal-averaged electrocardiograms in marathon runners.

    abstract::Late potentials have been shown to predict malignant ventricular arrhythmias and sudden cardiac death. To determine whether prolonged, strenuous activity is associated with the development of ventricular late potentials, signal-averaged electrocardiography was performed on 30 marathon runners before, immediately after...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(89)90010-0

    authors: Smith GS,Vacek JL,Wilson DB,Hawkins JW,Boyer TA

    更新日期:1989-12-01 00:00:00

  • C-Reactive protein and coronary artery disease: additional evidence of the implication of an inflammatory process in acute coronary syndromes.

    abstract:BACKGROUND:Inflammation might promote the development of atherosclerosis, and high levels of C-reactive protein (CRP) and fibrinogen are associated with an increased risk of acute coronary events. OBJECTIVE:We assessed the levels of CRP and other risk factors in patients with angiographically documented coronary arter...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1053/hj.1999.v137.92052

    authors: Abdelmouttaleb I,Danchin N,Ilardo C,Aimone-Gastin I,Angioï M,Lozniewski A,Loubinoux J,Le Faou A,Guéant JL

    更新日期:1999-02-01 00:00:00

  • Response of B-type natriuretic peptide to exercise in hypertensive patients with suspected diastolic heart failure: correlation with cardiac function, hemodynamics, and workload.

    abstract:BACKGROUND:Diastolic heart failure (DHF) is characterized by dyspnea due to increased left ventricular (LV) filling pressures during stress. We sought the relationship of exercise-induced increases in B-type natriuretic peptide (BNP) to LV filling pressures and parameters of cardiovascular performance in suspected DHF....

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2004.02.012

    authors: Mottram PM,Haluska BA,Marwick TH

    更新日期:2004-08-01 00:00:00

  • Effects of prostacyclin on systemic and coronary hemodynamics in the dog.

    abstract::The hemodynamic effects of intravenous and intracoronary prostacyclin (PGI2) were evaluated in anesthetized, open-chest instrumented dogs. Coronary artery and aortic blood flows, aortic and left ventricular (LV) diastolic pressure, and heart rate were measured continuously. With intravenous PGI2 both left anterior des...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(81)90033-8

    authors: Mehta J,Nichols WW,Mehta P,Pepine C,Conti CR

    更新日期:1981-11-01 00:00:00

  • Abnormal changes in transmitral flow after acute exposure to nitroglycerin and nifedipine in uncomplicated insulin-dependent diabetes mellitus: a Doppler echocardiographic study.

    abstract::To study the left ventricular (LV) diastolic function in uncomplicated insulin-dependent diabetic patients without hypertension (n = 25) and comparable controls (n = 15), the effect of acute administration of nitroglycerin and nifedipine on cavity dimensions and transmitral flow pattern was investigated by Doppler ech...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(93)90542-h

    authors: Gøtzsche O,Sihm I,Lund S,Schmitz O

    更新日期:1993-12-01 00:00:00

  • Percutaneous transluminal coronary angioplasty in acute myocardial infarction.

    abstract::Percutaneous transluminal coronary angioplasty (PTCA) has, in general, been restricted to therapy for patients with angina pectoris. Thrombolytic therapy and guide wire recanalization have been used to recanalize coronary arteries in patients with evolving myocardial infarction. Recently we and others have examined th...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(84)90352-1

    authors: Pepine CJ,Prida X,Hill JA,Feldman RL,Conti CR

    更新日期:1984-04-01 00:00:00

  • How to use ACE-inhibitors, beta-blockers, and newer therapies in AMI.

    abstract::Besides reperfusion treatment, which is the most powerful approach to the underlying pathophysiological cause of myocardial infarction, adjunctive therapies should be considered to reduce clinical symptoms, and improve left ventricular function and mortality rates. Randomized clinical trials and overviews of adjunctiv...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/s0002-8703(99)70341-8

    authors: Maggioni AP,Latini R

    更新日期:1999-08-01 00:00:00

  • Apixaban compared with parenteral heparin and/or vitamin K antagonist in patients with nonvalvular atrial fibrillation undergoing cardioversion: Rationale and design of the EMANATE trial.

    abstract:BACKGROUND:Stroke prevention in anticoagulation-naïve patients with atrial fibrillation undergoing cardioversion has not been systematically studied. OBJECTIVE:To determine outcomes in anticoagulation-naïve patients (defined as those receiving an anticoagulant for <48 hours during the index episode of atrial fibrillat...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2016.06.008

    authors: Ezekowitz MD,Pollack CV,Sanders P,Halperin JL,Spahr J,Cater N,Petkun W,Breazna A,Kirchhof P,Oldgren J

    更新日期:2016-09-01 00:00:00

  • Oxygen uptake efficiency slope, a new submaximal parameter in evaluating exercise capacity in chronic heart failure patients.

    abstract:BACKGROUND:The oxygen uptake efficiency slope (OUES) is a new submaximal parameter which objectively predicts the maximal exercise capacity in children and healthy subjects. However, the usefulness of OUES in adult patients with and without advanced heart failure remains undetermined. The present study investigates the...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2004.07.004

    authors: Van Laethem C,Bartunek J,Goethals M,Nellens P,Andries E,Vanderheyden M

    更新日期:2005-01-01 00:00:00