Dependency of premature ventricular contractions on heart rate.

Abstract:

:To identify a method for characterizing the dynamic behavior of ventricular arrhythmias at different heart rates, 201 consecutive patients with frequent premature ventricular contractions (PVCs) underwent two 24-hour electrocardiographic monitoring periods. The percentage of PVCs for each cycle length was calculated and then analyzed by linear regression analysis. On the basis of the significance of the p value, and the positive or negative value of the slope, we identified three trends: a tachycardia-enhanced pattern (p < 0.01, slope negative), a bradycardia-enhanced pattern (p < 0.01, slope positive), and an indifferent pattern (p > 0.01). During the first monitoring period, a tachycardia-enhanced pattern was present in 56 patients (28%), a bradycardia-enhanced pattern was present in 49 patients (24%), and an indifferent pattern was present in 96 patients (48%). This relationship was reproducible in 41 of the patients with a tachycardia-enhanced pattern (73%), in 29 of the patients with a bradycardia-enhanced pattern (59%), and in 70 patients with an indifferent pattern (72%). In conclusion, it is possible to identify a spontaneous trend between the incidence of ventricular arrhythmias and the length of the preceding cardiac cycle that seems to remain stable over time.

journal_name

Am Heart J

journal_title

American heart journal

authors

Pitzalis MV,Mastropasqua F,Massari F,Passantino A,Forleo C,Luzzi G,Totaro P,De Nicolò M,Rizzon P

doi

10.1016/s0002-8703(97)70203-5

subject

Has Abstract

pub_date

1997-02-01 00:00:00

pages

153-61

issue

2

eissn

0002-8703

issn

1097-6744

pii

S0002870397000239

journal_volume

133

pub_type

杂志文章
  • Changes in myocardial metabolism and transcardiac electrolytes during simulated ventricular tachycardia: effects of beta-adrenergic blockade.

    abstract::Myocardial ischemia, electrolyte changes, and fluctuations in autonomic tone may play an important role in the presentation of malignant ventricular arrhythmias. beta-Adrenoceptor blocking agents have been shown to decrease the incidence of ventricular fibrillation and sudden cardiac death in patients with coronary ar...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(94)90015-9

    authors: Peuhkurinen KJ,Huikuri HV,Linnaluoto M,Takkunen JT

    更新日期:1994-07-01 00:00:00

  • Pharmacologic characteristics of a new calcium antagonist, manidipine: beneficial effects on renal circulation and vascular changes.

    abstract::The calcium antagonist, manidipine, was developed on the basis of the hypothesis that antihypertensive drugs that act to improve renal hemodynamic alterations will be therapeutically beneficial in hypertensive patients. Manidipine shows long-lasting calcium channel-blocking action in vascular smooth muscle cells and a...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/0002-8703(93)90203-l

    authors: Nagaoka A

    更新日期:1993-02-01 00:00:00

  • Incidence of severe renal dysfunction among individuals taking warfarin and implications for non-vitamin K oral anticoagulants.

    abstract:BACKGROUND:The purpose of this study is to assess incidence and risk factors for severe renal dysfunction in patients requiring oral anticoagulation to help guide initial drug choice and provide a rational basis for interval monitoring of renal function for patients prescribed non-vitamin K oral anticoagulants. METHOD...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2016.08.017

    authors: Fanola CL,Mooney D,Cowan AJ,Ko D,Sisson EK,Henault LE,Tripodis Y,Hylek EM

    更新日期:2017-02-01 00:00:00

  • Comparison of clinical features of non-Q wave and Q wave myocardial infarction.

    abstract::The clinical spectrum and outcome of 119 patients with acute non-Q wave myocardial infarction (NQMI) were studied, in comparison with those of 354 patients with acute Q wave myocardial infarction (QMI). The patients with NQMI had a significantly higher incidence of preinfarction angina (73% vs 63%), previous myocardia...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(86)90056-6

    authors: Ogawa H,Hiramori K,Haze K,Saito M,Sumiyoshi T,Fukami K,Goto Y,Ikeda M

    更新日期:1986-03-01 00:00:00

  • Effects of immunoadsorption and subsequent immunoglobulin G substitution on cardiopulmonary exercise capacity in patients with dilated cardiomyopathy.

    abstract:BACKGROUND:Recent data indicate that cardiac antibodies play an active role in the pathogenesis of dilated cardiomyopathy (DCM) and may contribute to cardiac dysfunction in patients with DCM. The present study investigated the influence of immunoadsorption with subsequent immunoglobulin G substitution (IA/IgG) on cardi...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2010.01.012

    authors: Herda LR,Trimpert C,Nauke U,Landsberger M,Hummel A,Beug D,Kieback A,Dörr M,Empen K,Knebel F,Ewert R,Angelow A,Hoffmann W,Felix SB,Staudt A

    更新日期:2010-05-01 00:00:00

  • The Italian Registry for hypertrophic cardiomyopathy: a nationwide survey.

    abstract:BACKGROUND:National registries are advocated as instrumental to the solution of rarity-related problems for patients with hypertrophic cardiomyopathy (HCM), including limited access to advanced treatment options. Thus, an Italian Registry for HCM was created to assess the clinical profile and the level of care nationwi...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2005.01.005

    authors: Cecchi F,Olivotto I,Betocchi S,Rapezzi C,Conte MR,Sinagra G,Zachara E,Gavazzi A,Rordorf R,Carnemolla G,Porcu M,Nistri S,Gruppillo P,Giampaoli S

    更新日期:2005-11-01 00:00:00

  • Is long-term pharmacist-managed anticoagulation service efficient? A pragmatic randomized controlled trial.

    abstract:BACKGROUND:Some pharmacist-managed anticoagulation services (PMAS) provide initial follow-up to patients on oral anticoagulant, who are transferred to their physician once they are stabilized. This may be as effective as and less expensive than long-term PMAS follow-up. METHODS:Once PMAS patients were stabilized and r...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2008.02.009

    authors: Lalonde L,Martineau J,Blais N,Montigny M,Ginsberg J,Fournier M,Berbiche D,Vanier MC,Blais L,Perreault S,Rodrigues I

    更新日期:2008-07-01 00:00:00

  • Modifiable factors associated with failure to attain low-density lipoprotein cholesterol goal at 6 months after acute myocardial infarction.

    abstract:BACKGROUND:Although controversial, reducing low-density lipoprotein cholesterol (LDL-C) to target levels remains a common therapeutic goal after acute myocardial infarction (AMI). We sought to illuminate patient and provider characteristics associated with LDL-C goal nonattainment after AMI. METHODS:In an observationa...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2012.10.005

    authors: Martin SS,Gosch K,Kulkarni KR,Spertus JA,Mathews R,Ho PM,Maddox TM,Newby LK,Alexander KP,Wang TY

    更新日期:2013-01-01 00:00:00

  • Resting thallium-201 myocardial perfusion patterns in patients with severe left ventricular dysfunction: differences between patients with primary cardiomyopathy, chronic coronary artery disease, or acute myocardial infarction.

    abstract::This study examined the value of resting thallium-201 imaging in differentiating patients with primary cardiomyopathy from those with ischemic cardiomyopathy. There were 15 patients with primary cardiomyopathy (group I); 20 with chronic CAD (group II); and 25 with acute Q wave myocardial infarction (group III). All pa...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(86)90113-4

    authors: Iskandrian AS,Hakki AH,Kane S

    更新日期:1986-04-01 00:00:00

  • Diet and incident venous thromboembolism: the Iowa Women's Health Study.

    abstract:BACKGROUND:Little is known about the role of diet in the development of venous thromboembolism (VTE). We explored the prospective relation of dietary patterns, food groups, and nutrients to incident VTE in older women. METHODS:In 1986, Iowa women aged 55 to 69 years completed a mailed survey, including a 127-item food...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2009.04.003

    authors: Lutsey PL,Steffen LM,Virnig BA,Folsom AR

    更新日期:2009-06-01 00:00:00

  • Abnormal quinidine binding in survivors of prehospital cardiac arrest.

    abstract::Quinidine binding was studied in 15 survivors of prehospital cardiac arrest and was compared to 18 normal individuals and 20 patients with coronary artery disease. The unbound quinidine fraction was 6.3 +/- 2.8% in the survivors of prehospital cardiac arrest, a value significantly lower than normal individuals (unboun...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(84)90312-0

    authors: Kessler KM,Lisker B,Conde C,Silver J,Ho-Tung P,Hamburg C,Myerburg RJ

    更新日期:1984-04-01 00:00:00

  • Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies.

    abstract:BACKGROUND:Multiple genetic loci are associated with clinical cardiovascular (CV) disease and individual CV risk factors. Individuals with ideal levels of all major CV risk factors have very low risk for CV disease morbidity or mortality. Ideal levels of risk factors can be attained by lifestyle modifications; however,...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.ahj.2015.12.022

    authors: Allen NB,Lloyd-Jones D,Hwang SJ,Rasmussen-Torvik L,Fornage M,Morrison AC,Baldridge AS,Boerwinkle E,Levy D,Cupples LA,Fox CS,Thanassoulis G,Dufresne L,Daviglus M,Johnson AD,Reis J,Rotter J,Palmas W,Allison M,Pankow J

    更新日期:2016-05-01 00:00:00

  • The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chr

    abstract:OBJECTIVES:The DANHEART trial is a multicenter, randomized (1:1), parallel-group, double-blind, placebo-controlled study in chronic heart failure patients with reduced ejection fraction (HFrEF). This investigator driven study will include 1500 HFrEF patients and test in a 2 × 2 factorial design: 1) if hydralazine-isoso...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2020.09.020

    authors: Wiggers H,Køber L,Gislason G,Schou M,Poulsen MK,Vraa S,Nielsen OW,Bruun NE,Nørrelund H,Hollingdal M,Barasa A,Bøttcher M,Dodt K,Hansen VB,Nielsen G,Knudsen AS,Lomholdt J,Mikkelsen KV,Jonczy B,Brønnum-Schou J,Poenar

    更新日期:2021-01-01 00:00:00

  • Safety of elective--including "high risk"--percutaneous coronary interventions without on-site cardiac surgery.

    abstract:BACKGROUND:Current guidelines (American College of Cardiology/American Heart Association) for percutaneous coronary intervention (PCI) limit the performance of elective cases to hospitals with the capability for cardiac surgery. The number of hospitals in the United States with this capability is limited, which restric...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2004.03.040

    authors: Zavala-Alarcon E,Cecena F,Ashar R,Patel R,Van Poppel S,Carlson R

    更新日期:2004-10-01 00:00:00

  • Adverse diastolic remodeling after reperfused ST-elevation myocardial infarction: An important prognostic indicator.

    abstract:OBJECTIVES:We sought to determine the relationship of adverse diastolic remodeling (ie, worsening diastolic or persistent restrictive filling) with infarct scar characteristics, and to evaluate its prognostic value after ST-segment elevation myocardial infarction (STEMI). BACKGROUND:Severe diastolic dysfunction (restr...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2016.05.020

    authors: Nguyen TL,Phan J,Hogan J,Hee L,Moses D,Otton J,Premawardhana U,Rajaratnam R,Juergens CP,Dimitri H,French JK,Richards D,Thomas L

    更新日期:2016-10-01 00:00:00

  • Coronary artery bypass surgery in patients with acute coronary syndromes is difficult to predict.

    abstract:BACKGROUND:Although the use of clopidogrel in patients "unlikely" to require coronary artery bypass grafting (CABG) is recommended in current guidelines of acute coronary syndrome (ACS) management, an important minority of patients require CABG. We assessed the ability to predict need for CABG from demographics known a...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2007.12.002

    authors: Chew DP,Mahaffey KW,White HD,Huang Z,Hoekstra JW,Ferguson JJ,Califf RM,Aylward PE

    更新日期:2008-05-01 00:00:00

  • Incidence and clinical relevance of supraventricular tachyarrhythmias in pulmonary hypertension.

    abstract:BACKGROUND:In patients with severe pulmonary hypertension (PH), right ventricular function is a main determinant of clinical stability and outcome. Supraventricular tachyarrhythmias (SVTs) may compromise cardiac function and threaten prognosis in patients with PH, but the incidence and clinical relevance of SVTs in PH ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2006.09.008

    authors: Tongers J,Schwerdtfeger B,Klein G,Kempf T,Schaefer A,Knapp JM,Niehaus M,Korte T,Hoeper MM

    更新日期:2007-01-01 00:00:00

  • Atrial fibrillation: A major risk factor for cognitive decline.

    abstract::Atrial fibrillation is a common disease of the elderly, conferring considerable morbidity and mortality related to cardiovascular effects and thromboembolic risks. Anticoagulation, antiarrhythmic medications, and rate control are the cornerstone of contemporary management, whereas ablation and evolving surgical techni...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/j.ahj.2014.12.015

    authors: Hui DS,Morley JE,Mikolajczak PC,Lee R

    更新日期:2015-04-01 00:00:00

  • The alpha1-adrenergic blocker urapidil improves contractile function in patients 3 months after coronary stenting: a randomized, double-blinded study.

    abstract:BACKGROUND:The recovery of left ventricular function (LVF) after revascularization takes time. alpha-Adrenergic blockade acutely improves coronary blood flow and LVF, whereas the effects of more prolonged alpha-adrenergic blockade on LVF recovery after stenting are unknown. METHODS:In 32 patients (age 58 +/- 12 y) wit...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.ahj.2003.08.005

    authors: Kozàkovà M,Marco J,Heusch G,Bernies M,Bossi IM,Palombo C,Anguissola GB,Donatelli F,Laurent JP,Gregorini L

    更新日期:2004-02-01 00:00:00

  • High-dose, brief intravenous streptokinase early in acute myocardial infarction.

    abstract::An acute thrombus at the proximal border of a high-grade atherosclerotic obstruction is the usual cause of myocardial infarction. Although intracoronary thrombolysis is potentially an exciting new therapy for reducing the extent of myocardial infarction by lysing coronary clot, a number of major difficulties limit its...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-8703(82)90267-8

    authors: Spann JF,Sherry S,Carabello BA,Mann RH,McCann WD,Gault JH,Gentzler RD,Rosenberg KM,Maurer AH,Denenberg BS,Warner HF,Rubin RN,Malmud LS,Comerota A

    更新日期:1982-10-01 00:00:00

  • Mitral valve prolapse in anxiety neurosis (panic disorder).

    abstract::Our purpose was to determine the incidence of mitral valve prolapse in patients with anxiety neurosis or panic disorder, with symptoms including recurrent anxiety attacks, dyspnea, palpitations, chest pain, dizziness, and paresthesias. Twenty-one patients and 20 age- and sex-matched normal controls were studied. Objec...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(80)90142-8

    authors: Venkatesh A,Pauls DL,Crowe R,Noyes R Jr,Van Valkenburg C,Martins JB,Kerber RE

    更新日期:1980-09-01 00:00:00

  • Variable inhibition of high-shear-induced platelet plug formation by eptifibatide and tirofiban under conditions of platelet activation and high von Willebrand release: a randomized, placebo-controlled, clinical trial.

    abstract:BACKGROUND:Glycoprotein (GP) IIb/IIIa antagonists have become a mainstay for the treatment of acute coronary syndromes. Yet, they have rarely been evaluated under relevant pathophysiologic conditions, for example, high shear rates in the presence of physiologic calcium concentrations. We compared the efficacy of eptifi...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.ahj.2003.11.003

    authors: Derhaschnig U,Pachinger C,Jilma B

    更新日期:2004-04-01 00:00:00

  • Dronedarone and vitamin K antagonists: a review of drug-drug interactions.

    abstract::Adverse drug events affect millions of patients each year. An important drug-drug interaction between amiodarone and vitamin K antagonists is encountered frequently in daily clinical practice. Warfarin, a commonly used anticoagulant, is a mixture of 2 optically active isomers (R and S enantiomers). The S enantiomer is...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/j.ahj.2010.07.008

    authors: Shirolkar SC,Fiuzat M,Becker RC

    更新日期:2010-10-01 00:00:00

  • Congenital pericardial defect associated with cardiac incarceration: case report.

    abstract::1. A 4-year-old boy with the congenital partial defect of the left pericardium who presented with myocardial infarction, died of incarceration of the left ventricle. 2. This is the fourth reported case of death from this anomaly in the world. 3. Because this anomaly occasionally causes sudden death, it is important to...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(80)90068-x

    authors: Saito R,Hotta F

    更新日期:1980-12-01 00:00:00

  • Two-dimensional echocardiographic study of right ventricular outflow and great artery anatomy in pulmonary atresia with ventricular septal defects and in truncus arteriosus.

    abstract::In this study, we reviewed M-mode and two-dimensional (2DE) echocardiographic observations in 13 patients with pulmonary atresia with ventricular septal defect and in six patients with truncus arteriosus in order to attempt to identify echocardiographic features distinguishing these two abnormalities in which no anato...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(83)90528-8

    authors: Vargas Barron J,Sahn DJ,Attie F,Valdes-Cruz LM,Grenadier E,Allen HD,Oliveira Lima C,Goldberg SJ

    更新日期:1983-02-01 00:00:00

  • The triglyceride-high-density lipoprotein axis: an important target of therapy?

    abstract::Coronary heart disease is the single largest cause of morbidity and mortality in the United States. The link between elevated low-density lipoprotein cholesterol (LDL-C) levels and coronary heart disease (CHD) has been clearly established. However, triglycerides (TG) are increasingly believed to be independently assoc...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/j.ahj.2004.03.037

    authors: Szapary PO,Rader DJ

    更新日期:2004-08-01 00:00:00

  • Combined use of high-sensitivity cardiac troponin T and N-terminal pro-B type natriuretic peptide improves measurements of performance over established mortality risk factors in chronic heart failure.

    abstract:BACKGROUND:Heart failure still maintains a high mortality. Biomarkers reflecting different pathophysiological pathways are under evaluation to better stratify the mortality risk. The objective was to assess high-sensitivity cardiac troponin T (hs-cTnT) in combination with N-terminal pro-B type natriuretic peptide (NT-p...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2012.03.004

    authors: de Antonio M,Lupon J,Galan A,Vila J,Urrutia A,Bayes-Genis A

    更新日期:2012-05-01 00:00:00

  • Outcomes and cost among Medicare beneficiaries hospitalized for heart failure assigned to accountable care organizations.

    abstract::Little is known about the impact of accountable care organizations (ACO) on hospitalized heart failure (HF) patients, a high-cost and high-risk population. OBJECTIVE:We linked Medicare fee-for-service claims from 2013 to 2015 with data from American Heart Association Get With The Guidelines-HF registry to compare HF ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2020.04.028

    authors: Luo N,Hammill BG,DeVore AD,Xu H,Fonarow GC,Albert NM,Matsouaka RA,Hernandez AF,Yancy C,Mentz RJ

    更新日期:2020-08-01 00:00:00

  • Short-term vitamin D3 supplementation lowers plasma renin activity in patients with stable chronic heart failure: an open-label, blinded end point, randomized prospective trial (VitD-CHF trial).

    abstract:BACKGROUND:Many chronic heart failure (CHF) patients have low vitamin D (VitD) and high plasma renin activity (PRA), which are both associated with poor prognosis. Vitamin D may inhibit renin transcription and lower PRA. We investigated whether vitamin D3 (VitD3) supplementation lowers PRA in CHF patients. METHODS AND...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2013.05.009

    authors: Schroten NF,Ruifrok WP,Kleijn L,Dokter MM,Silljé HH,Lambers Heerspink HJ,Bakker SJ,Kema IP,van Gilst WH,van Veldhuisen DJ,Hillege HL,de Boer RA

    更新日期:2013-08-01 00:00:00

  • Reproducibility of the signal-averaged electrocardiogram.

    abstract::Variation in measurements made from signal-averaged electrocardiograms was examined. Averaging 200 beats in 18 normal subjects, pairs of high-frequency QRS and low-amplitude signal durations correlated at immediate, short-term, and long-term intervals. The percent high-frequency (60 Hz to 120 Hz) voltages in the late ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(91)90283-n

    authors: Engel TR,Pierce DL,Patil KD

    更新日期:1991-12-01 00:00:00