Pharmacologic characteristics of a new calcium antagonist, manidipine: beneficial effects on renal circulation and vascular changes.

abstract：BACKGROUND:Studies document better survival in heart failure patients with decreased left ventricular ejection fraction (EF) and higher body mass index (BMI; kg/m(2)) compared to those with a lower BMI. However, it is unknown if this "obesity paradox" applies to heart failure patients with preserved EF or if it extends...

journal_title：American heart journal

authors： Kapoor JR,Heidenreich PA

更新日期：2010-01-01 00:00:00

abstract：:Previous studies have suggested that the contractility of isolated heart muscle removed from rabbits made hypercholesterolemic is decreased. As part of a study evaluating the effects of high-lipid diets on aortic atherosclerosis, we evaluated the contractility of perfused rabbit hearts. Six rabbits were placed on a hi...

journal_title：American heart journal

authors： Blumlein S,Sievers R,Wikman-Coffelt J,Parmley WW

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Although recent data support an early invasive management in acute coronary syndromes (ACS), overall evidence appears conflicting. We performed a metaregression to explore the impact of intracoronary stenting and aggressive antiplatelet treatment on the risk/benefit ratio of an early invasive approach. METH...

journal_title：American heart journal

authors： Biondi-Zoccai GG,Abbate A,Agostoni P,Testa L,Burzotta F,Lotrionte M,Trani C,Biasucci LM

更新日期：2005-03-01 00:00:00

abstract：:The electrocardiographic QT interval, with a wide variety of practical and theoretic applications in medicine, pharmacology, and cardiology, is critically dependent on heart rate as expressed by cycle length (RR). To account for this and permit intraindividual and interindividual comparisons of changing QT intervals, ...

journal_title：American heart journal

authors： Spodick DH,Rifkin RD,Rajasingh MC

更新日期：1990-07-01 00:00:00

abstract：:Currently available antiplatelet agents are limited in the scope and magnitude of platelet inhibition. Orally active platelet glycoprotein IIb/IIIa antagonists are currently in clinical testing. These agents may extend platelet inhibition and clinical benefit from parenteral glycoprotein IIb/IIIa antagonists. The most...

journal_title：American heart journal

authors： Kereiakes DJ

更新日期：1999-07-01 00:00:00

abstract：:We analyzed the long-term outcome of 198 patients after unsuccessful percutaneous transluminal coronary angioplasty. Forty-nine percent underwent emergency coronary artery bypass grafting surgery, 17% had elective bypass surgery, and 34% were treated medically. The in-hospital mortality rate was 4%, and myocardial inf...

journal_title：American heart journal

authors： Tuzcu M,Simpfendorfer C,Dorosti K,Franco I,Golding L,Hollman J,Whitlow P

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Stroke is a rare but serious event that complicates the course of patients with acute coronary syndromes (ACS). The type, outcome, and risk factors of stroke occurring in stabilized patients with ACS have not been previously reported. METHODS:We evaluated stroke incidence, subtypes, and outcomes, in additio...

journal_title：American heart journal

authors： Kassem-Moussa H,Mahaffey KW,Graffagnino C,Tasissa G,Sila CA,Simes RJ,White HD,Califf RM,Bhapkar MV,Newby LK,SYMPHONY and 2nd SYMPHONY Investigators.

更新日期：2004-09-01 00:00:00

abstract：:The aim of our study was to compare the outcome of patients with a first acute myocardial infarction (AMI) among three large cohorts of patients hospitalized between 1966 and 1992 in Israel, in view of changes in treatment facilities and investigation methods. Patients with a first AMI constituted 71% of all myocardia...

journal_title：American heart journal

authors： Behar S,Goldbourt U,Barbash G,Modan B

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to examine ethnic differences in depressive symptoms and antidepressant treatment in a cohort of patients undergoing diagnostic coronary angiography. BACKGROUND:Coronary heart disease (CHD) is the leading cause of mortality in the United States, with an excess of mortality in African...

journal_title：American heart journal

authors： Waldman SV,Blumenthal JA,Babyak MA,Sherwood A,Sketch M,Davidson J,Watkins LL

更新日期：2009-01-01 00:00:00

abstract：:Percutaneous transluminal coronary recanalization, a new therapeutic procedure used in acute myocardial infarction, offers significant reduction in mortality, as well as more effective limitation of the zone of infarction than has been possible with other pharmacologic treatment employed in the past. The risk of coron...

journal_title：American heart journal

authors： Rutsch W,Schartl M,Mathey D,Kuck K,Merx W,Dörr R,Rentrop P,Blanke H

更新日期：1981-12-01 00:00:00

abstract：:Calcium channel blockers and central alpha-agonists are among the classes of antihypertensive drugs that yield the most favorable overall effects on risk factors for hypertension-related end-organ damage. An open-label prospective trial in 42 patients with a mean baseline blood pressure of 144/102 mm Hg sought to asse...

journal_title：American heart journal

authors： Houston MC,Hays L

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:The few available studies of the Centers for Medicare and Medicaid Services Hospital Inpatient Quality Reporting (IQR) care process indicators have not linked receipt of recommended care processes in heart failure (HF) with lower mortality. Because the Veterans Health Administration (VHA) also tracks hospita...

journal_title：American heart journal

authors： Wu WC,Jiang L,Friedmann PD,Trivedi A

更新日期：2014-11-01 00:00:00

abstract：:Acute ventricular septal rupture in the setting of acute myocardial infarction continues to present clinicians with a difficult therapeutic dilemma. The role of surgical intervention and its timing remains unresolved. A collaborative study from three institutions was undertaken to examine various clinical outcomes in ...

journal_title：American heart journal

authors： Held AC,Cole PL,Lipton B,Gore JM,Antman EM,Hockman JS,Corrao J,Goldberg RJ,Alpert JS

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Although cross-sectional studies have identified lifestyle factors associated with high-density lipoprotein cholesterol (HDL-C), no studies have examined the association between changes in lifestyle factors and long-term changes in HDL-C. METHODS:We examined the association between changes in lifestyle fact...

journal_title：American heart journal

authors： Rahilly-Tierney C,Sesso HD,Djoussé L,Gaziano JM

更新日期：2011-04-01 00:00:00

abstract：:Quantitation of coronary luminal diameter with a 20 MHz mechanically rotating intravascular ultrasound (IVUS) catheter was compared with orthogonal-view cineangiography by use of a semiautomated edge-detection algorithm in 48 patients undergoing coronary angioplasty. Quantitative comparison of 196 matched segments was...

journal_title：American heart journal

authors： De Scheerder I,De Man F,Herregods MC,Wilczek K,Barrios L,Raymenants E,Desmet W,De Geest H,Piessens J

更新日期：1994-02-01 00:00:00

abstract：:Atherosclerotic coronary artery disease is a serious clinical problem. Clinicians dealing with patients can make a diagnosis of coronary disease in several ways. Unfortunately all too often the diagnosis is made via sudden death or acute myocardial infarction. At other times the diagnosis is made by evaluation of pati...

journal_title：American heart journal

authors： Anderson HV,King SB 3rd

更新日期：1992-05-01 00:00:00

abstract：:Pressor response to norepinephrine, cardiopulmonary blood volume, and hemodynamic parameters were studied in 41 borderline hypertensive patients in comparison with 42 permanent essential hypertensive patients and 28 normal subjects. Borderline hypertensive subjects had high cardiac index (p less than 0.0001), normal t...

journal_title：American heart journal

authors： Safar ME,London GM,Weiss YA,Milliez PL

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:The conventional use of 16-slice multidetector computed tomography (MDCT) remains somewhat limited for evaluating stenoses in vein graft distal anastomotic sites and in coronary arteries. We investigated the diagnostic accuracy of 64-slice MDCT for assessment of both grafts and coronary arteries in patients ...

journal_title：American heart journal

authors： Onuma Y,Tanabe K,Chihara R,Yamamoto H,Miura Y,Kigawa I,Fukuda S,Miyairi T,Nakajima H,Hara K

更新日期：2007-09-01 00:00:00

abstract：:This study correlates the anatomic pathologic coronary anatomy found by arteriography in each of three groups of symptomatic patients, all with coronary artery disease, divided according to the magnitude of ST-segment depression after an adequate submaximal treadmill exercise test. Group I consists of 45 patients with...

journal_title：American heart journal

authors： Cheitlin MD,Davia JE,de Castro CM,Barrow EA,Anderson WT

更新日期：1975-03-01 00:00:00

abstract：:We previously reported that single-head SPECT imaging with teboroxime is feasible. However, excessive hepatic uptake in some patients may interfere with image interpretation. This study examined the feasibility of improving image quality by use of a preprocessing masking technique to subtract hepatic activity. A band ...

journal_title：American heart journal

authors： Heo J,Iskandrian B,Cave V,Iskandrian AS

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVE:To date, few studies have evaluated asymptomatic patients with organic mitral regurgitation (MR). The goal of the present study was to assess the presence of independent predictive factors for progression of symptoms and/or left ventricular dysfunction (SLVSD) in this population. METHODS:We prospectively eva...

journal_title：American heart journal

authors： Krauss J,Pizarro R,Oberti PF,Falconi M,Cagide A

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Weekly fish consumption has been related to a lower risk of fatal coronary heart disease (CHD) and incident stroke in populations with a low fish intake. This relation has mainly been attributed to n-3 fatty acids in fish, that is, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). It is at present ...

journal_title：American heart journal

authors： Geleijnse JM,Giltay EJ,Schouten EG,de Goede J,Oude Griep LM,Teitsma-Jansen AM,Katan MB,Kromhout D,Alpha Omega Trial Group.

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The long-term prognostic significance of early (<48 hours) ventricular fibrillation (VF) or sustained ventricular tachycardia (VT) in patients with an acute myocardial infarction remains controversial. Emerging data suggest that some of the benefit of renin-angiotensin-aldosterone system (RAAS) antagonism ma...

journal_title：American heart journal

authors： Askari AT,Shishehbor MH,Kaminski MA,Riley MJ,Hsu A,Lincoff AM,GUSTO-V Investigators.

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Intramyocardial injection of autologous bone marrow (ABM) may induce angiogenesis. We tested the safety and feasibility of catheter-based direct percutaneous intramyocardial delivery of ABM in patients with refractory angina pectoris. METHODS:Ten patients (9 men, 67 +/- 8 years) with refractory angina (Cana...

journal_title：American heart journal

authors： Briguori C,Reimers B,Sarais C,Napodano M,Pascotto P,Azzarello G,Bregni M,Porcellini A,Vinante O,Zanco P,Peschle C,Condorelli G,Colombo A

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:As stenting practice has evolved to include greater numbers of stents and adjunctive balloon catheters per case, concern has focused on the increasing costs of equipment for the delivery of stents. METHODS AND RESULTS:To evaluate temporal changes in costs of intracoronary stenting, we examined total costs, ...

journal_title：American heart journal

authors： Vaitkus PT,Adele C,Wells SK,Zehnacker JP

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:To examine the safety and efficacy of cangrelor in patients with single-vessel disease (SVD) and multi-vessel disease (MVD). BACKGROUND:Cangrelor, an intravenous, rapidly acting P2Y12 inhibitor, is superior to clopidogrel in reducing ischemic events among patients receiving percutaneous coronary intervention...

journal_title：American heart journal

authors： Abnousi F,Sundaram V,Yong CM,Prats J,Deliargyris EN,Stone GW,Hamm CW,Steg PG,Gibson CM,White HD,Price MJ,Généreux P,Desai M,Yang L,Ding VY,Harrington RA,Bhatt DL,Mahaffey KW

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The follow-up of patients with mitral and tricuspid regurgitation is important for their clinical treatment. We aimed to evaluate the reproducibility of the flow convergence method in mitral and tricuspid regurgitation. METHODS:The proximal flow convergence region was imaged with color Doppler ultrasound sc...

journal_title：American heart journal

authors： Grossmann G,Hoffmeister A,Imhof A,Giesler M,Hombach V,Spiess J

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Cell adhesion molecules are key regulators of atherosclerotic plaque development, but circulating levels of soluble fragments, such as intercellular adhesion molecule (sICAM-1) and vascular cell adhesion molecule (sVCAM-1), have yielded conflicting associations with atherosclerotic cardiovascular disease (AS...

journal_title：American heart journal

authors： Ren HY,Khera A,de Lemos JA,Ayers CR,Rohatgi A

更新日期：2017-09-01 00:00:00

abstract：:The relationship between myocardial sites with late activation during sinus rhythm and sites critical for the initiation and sustentation of reentrant ventricular tachycardia was systematically examined in the 4-day-old postinfarction canine heart. The critical sites for prevention of the initiation of reentry and for...

journal_title：American heart journal

authors： Assadi M,Restivo M,Gough WB,el-Sherif N

更新日期：1990-05-01 00:00:00

abstract：OBJECTIVES:SUPPORT-HF 2 tests the hypothesis that home monitoring with information technology-supported specialist management is more effective in optimizing medical therapy than is home monitoring alone for patients with heart failure. METHODS AND RESULTS:The study was designed as a 2-armed partially blinded parallel...

journal_title：American heart journal

authors： SUPPORT-HF 2 Investigators and Committees. Electronic address: kazem.rahimi@georgeinstitute.ox.ac.uk.

更新日期：2019-02-01 00:00:00