Modern approaches to the diagnosis of coronary artery disease.

abstract：BACKGROUND:Left atrial appendage flow velocity (LAAFV) is a predictor of thromboembolism in atrial fibrillation (AF) patients, as well as CHA2DS2-VASc score. However, little is known about LAAFV in sinus rhythm (SR) after catheter ablation. The aim of this study was to determine clinical predictors of low LAAFV in pati...

journal_title：American heart journal

authors： Kusa S,Komatsu Y,Taniguchi H,Uchiyama T,Takagi T,Nakamura H,Miyazaki S,Hachiya H,Iesaka Y

更新日期：2015-02-01 00:00:00

abstract：:Adverse drug events affect millions of patients each year. An important drug-drug interaction between amiodarone and vitamin K antagonists is encountered frequently in daily clinical practice. Warfarin, a commonly used anticoagulant, is a mixture of 2 optically active isomers (R and S enantiomers). The S enantiomer is...

journal_title：American heart journal

authors： Shirolkar SC,Fiuzat M,Becker RC

更新日期：2010-10-01 00:00:00

abstract：:Oxygen free radical scavengers have been found to decrease infarct size in dogs subjected to myocardial ischemia-reperfusion injury. A baboon open-chest model was used to determine if superoxide dismutase (SOD), an oxygen free radical scavenger, together with catalase would be equally effective in subhuman primates (b...

journal_title：American heart journal

authors： Watanabe BI,Premaratne S,Limm W,Mugiishi MM,McNamara JJ

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Calcified lesions carry the risk of suboptimal stent expansion. The purpose of this study was to investigate the impact of target lesion calcification on intracoronary ultrasound (ICUS) guided stent expansion after rotational atherectomy. METHODS:Stent expansion was assessed by ICUS in 39 patients with the ...

journal_title：American heart journal

authors： Henneke KH,Regar E,König A,Werner F,Klauss V,Metz J,Theisen K,Mudra H

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Afterload reduction decreases volume overload on the left ventricle and may thereby delay the need for valve replacement in chronic asymptomatic aortic regurgitation. The aims of this randomized double-blind, placebo-controlled trial were to examine short- and long-term hemodynamic effects of felodipine in c...

journal_title：American heart journal

authors： Søndergaard L,Aldershvile J,Hildebrandt P,Kelbaek H,Ståhlberg F,Thomsen C

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:The purpose of the current study was to determine whether survival after revascularization (coronary artery bypass grafting or percutaneous transluminal coronary angioplasty) is influenced by the extent of electrocardiographic (ECG) evidence of previous myocardial infarction (MI) in patients with ischemic ca...

journal_title：American heart journal

authors： Shah BR,Velazquez E,Shaw LK,Bart B,O'Connor C,Wagner GS

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Peak exercise oxygen consumption (peak VO2) is an important discriminator of survival in patients with systolic heart failure and is used to select ambulatory patients for transplantation. The major trials assessing the relationship between peak VO2 and survival have used a variety of low-level exercise prot...

journal_title：American heart journal

authors： Strzelczyk TA,Cusick DA,Pfeifer PB,Bondmass MD,Quigg RJ

更新日期：2001-09-01 00:00:00

abstract：:Adenosine infusion is accompanied by increases in coronary blood flow and myocardial blood volume. Myocardial blood volume may produce changes in diastolic left ventricular (LV) performance by increasing myocardial turgor. Diastolic dysfunction may also be the result of myocardial ischemia. The relation between change...

journal_title：American heart journal

authors： Ren JF,Pancholy SB,Kegel JG,Lighty GW Jr,Heo J,Iskandrian AS

更新日期：1995-04-01 00:00:00

abstract：:To assess the role of oxidative stress in exercise intolerance in patients with heart failure, a symptom-limited exercise test was performed with a bicycle ergometer in 12 patients with heart failure and in 7 members of a healthy control group. Level of plasma malondialdehyde, a marker of lipid peroxidation, at rest w...

journal_title：American heart journal

authors： Nishiyama Y,Ikeda H,Haramaki N,Yoshida N,Imaizumi T

更新日期：1998-01-01 00:00:00

abstract：:To investigate the significance of atrial natriuretic polypeptide (ANP) in essential hypertension, we measured plasma ANP concentrations in 43 subjects with essential hypertension uncomplicated by cardiac or renal failure, in 16 subjects with borderline hypertension, and in 17 normotensive control subjects. Plasma ANP...

journal_title：American heart journal

authors： Kohno M,Yasunari K,Matsuura T,Murakawa K,Takeda T

更新日期：1987-05-01 00:00:00

abstract：:An 84-year-old female who previously underwent repair of an atrial septal defect had evidence of increased reflectiveness of the posterior tricuspid anulus in the apical four-chamber view and the right ventricular two-chamber view. In addition, the inferior vena cava was dilated and during contrast echocardiography, c...

journal_title：American heart journal

authors： Mattleman S,Panidis I,Kotler MN,Mintz GS,Morganroth J,Ross J,Victor M

更新日期：1984-05-01 00:00:00

abstract：:The relation of alcohol consumption to coronary heart disease (CHD) was examined in a cohort of 1910 employed men aged 38 to 55 years enrolled in the Albany Study, a prospective investigation of factors related to cardiovascular disease. Two follow-up periods were examined, one between 1953-54 and 1971-72, the other a...

journal_title：American heart journal

authors： Gordon T,Doyle JT

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Erectile dysfunction (ED) is a common disorder in middle-aged men and is significantly influenced by cardiovascular risk factors (CVRFs) and cardiovascular disease. The substudy of the ONTARGET/TRANSCEND trials evaluates the relationship of erectile function to baseline characteristics and current treatment ...

journal_title：American heart journal

authors： Böhm M,Baumhäkel M,Probstfield JL,Schmieder R,Yusuf S,Zhao F,Koon T,ONTARGET\/TRANSCEND ED-Investigators.

更新日期：2007-07-01 00:00:00

abstract：:Baroreflex modulation of forearm vascular resistance (FVR) has been reported to be abnormal in patients with congestive heart failure (CHF). However, the neurohumoral mechanisms for this impairment are not defined. We assessed the responses of arterial pressure, FVR, plasma norepinephrine, and plasma renin activity to...

journal_title：American heart journal

authors： Mohanty PK,Arrowood JA,Ellenbogen KA,Thames MD

更新日期：1989-07-01 00:00:00

abstract：:In 30 years of follow-up in the Framingham study, routine biennial ECG examinations revealed 315 subjects with ECG-LVH and 164 with unrecognized ECG-MI without previous cardiac explanation. Among subjects initially free of clinically evident coronary heart disease and both ECG abnormalities, the incidence of ECG-LVH w...

journal_title：American heart journal

authors： Kannel WB,Abbott RD

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Left atrial (LA) volume is a prognostic index in chronic mitral regurgitation (MR). However, little is known about LA function in this setting. We hypothesized that LA dysfunction is related to pulmonary hypertension in chronic MR. METHODS:Seventy-one patients with organic chronic MR who underwent real-time...

journal_title：American heart journal

authors： Saraiva RM,Yamano T,Matsumura Y,Takasaki K,Toyono M,Agler DA,Greenberg N,Thomas JD,Shiota T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Insulin, in addition to its known metabolic effects, has sympatho-excitatory and vasodilatory actions on muscular blood vessels. The goal of this study was to evaluate insulin sensitivity in young women with vasovagal syncope and positive tilt test results (HUT+) and to compare it with that in patients with ...

journal_title：American heart journal

authors： Ruiz GA,Calvar C,Hermes R,Rivadeneira D,Bengolea V,Chirife R,Tentori MC,Gelpi RJ

更新日期：2003-05-01 00:00:00

abstract：:The clinical course and coronary arteriographic findings in eight patients with Prinzmetal's variant angina pectoris are reviewed and contrasted to previously reported cases. In six patients with S-T-elevation inferiorly, three had normal coronary arteriograms, one had complete right coronary artery occlusion, one ha...

journal_title：American heart journal

authors： Donsky MS,Harris MD,Curry GC,Blomqvist CG,Willerson JT,Mullins CB

更新日期：1975-05-01 00:00:00

abstract：:This study sought to determine whether early treatment with angiotensin-converting enzyme (ACE) inhibitors in patients with acute myocardial infarction (AMI) is useful for the improvement of fibrinolytic function, as well as left ventricular function. This study was designed to examine the levels of plasma plasminogen...

journal_title：American heart journal

authors： Oshima S,Ogawa H,Mizuno Y,Yamashita S,Noda K,Saito T,Sumida H,Suefuji H,Kaikita K,Soejima H,Yasue H

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:There are limited data assessing statin therapy in patients with nonobstructive coronary plaque on coronary computed tomography angiography (CCTA). METHODS:Two hundred six consecutive patients with mild noncalcified plaque on CCTA were enrolled in this multicenter prospective observational study. Subjects w...

journal_title：American heart journal

authors： Li Z,Hou Z,Yin W,Liu K,Gao Y,Xu H,Yu F,Ma Z,Yu W,Yang L,Lu B

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Although recent data support an early invasive management in acute coronary syndromes (ACS), overall evidence appears conflicting. We performed a metaregression to explore the impact of intracoronary stenting and aggressive antiplatelet treatment on the risk/benefit ratio of an early invasive approach. METH...

journal_title：American heart journal

authors： Biondi-Zoccai GG,Abbate A,Agostoni P,Testa L,Burzotta F,Lotrionte M,Trani C,Biasucci LM

更新日期：2005-03-01 00:00:00

abstract：:The neutral alkaloid, ryanodine, has several actions on cardiac muscle. To delineate better its mode of action, we studied ryanodine's effect upon contracting cat papillary muscles under changing loading conditions and stimulation frequencies. We also studied ryanodine's physiologic and metabolic effects upon isolated...

journal_title：American heart journal

authors： Blumlein SL,Sievers R,Wikman-Coffelt J,Parmley WW,Rouleau JL

更新日期：1985-08-01 00:00:00

abstract：:We tested the efficacy of microwave-frequency energy for ablating atrial tachycardia in eight open-chest dogs. Five other dogs served as controls. Atrial tachycardia was induced by direct application of aconitine crystals to the epicardial atrial surface or by injection of aconitine solution (0.15 mg/ml) into the righ...

journal_title：American heart journal

authors： Rho TH,Ito M,Pride HP,Waller B,Zipes DP

更新日期：1995-05-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) produces high-resolution images of great-vessel anatomy in pediatric patients. In this study seven patients, aged 6 to 27 months were evaluated by using gated MRI and two-dimensional echocardiography 4 to 26 months after arterial switch operation for D-transposition of the great arteri...

journal_title：American heart journal

authors： Hardy CE,Helton GJ,Kondo C,Higgins SS,Young NJ,Higgins CB

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:In patients with atrial fibrillation, incomplete adherence to anticoagulants increases risk of stroke. Non-warfarin oral anticoagulants (NOACs) are expensive; we evaluated whether higher copayments are associated with lower NOAC adherence. METHODS:Using a national claims database of commercially-insured pat...

journal_title：American heart journal

authors： Rome BN,Gagne JJ,Avorn J,Kesselheim AS

更新日期：2021-01-14 00:00:00

abstract：BACKGROUND:Preoperative use of angiotensin-blocking drug therapy (ABDT) with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and its link to occurrence of postoperative atrial fibrillation (POAF), a common marker of poor outcomes after cardiac surgery, remain controversial. METHODS:From 19...

journal_title：American heart journal

authors： Rader F,Van Wagoner DR,Gillinov AM,Blackstone EH

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Balloon inflation during coronary angioplasty results in shear stress-induced vessel wall injury with development of restenosis. This randomized trial compared the impact of two different balloon inflation strategies (slow versus fast) on restenosis after coronary angioplasty. METHODS:Two hundred seven pati...

journal_title：American heart journal

authors： Miketic S,Carlsson J,Tebbe U

更新日期：1998-04-01 00:00:00

abstract：:To evaluate the stability of precordial ST-segment mapping techniques in assessing ischemic myocardial injury, we studied 28 patients with acute anterior myocardial infarction using a 49-lead electrocardiographic system (1 mV. = 10 mm.). The sum of ST elevations in millimeters was taken as an index of ischemic injury,...

journal_title：American heart journal

authors： Madias JE,Hood WB Jr

更新日期：1977-05-01 00:00:00

abstract：:The expansion of antiarrhythmic therapy beyond pharmacologic agents to include surgery, devices, and ablation procedures, plus the reaffirmation by the Cardiac Arrhythmia Suppression Trial (CAST) of the need for concurrent placebo-controlled trials to establish a mortality benefit, have resulted in the need to conside...

journal_title：American heart journal

authors： Myerburg RJ,Kessler KM,Chakko S,Cox MM,Fernandez P,Interian A Jr,Castellanos A

更新日期：1994-04-01 00:00:00

abstract：:The purpose of this study were to determine the specificity of the head-up tilt test in normal subjects when a graded isoproterenol infusion is used, and to evaluate the role of dynamic ventricular volume change during head-up tilt as a mechanism of syncope. We prospectively studied 12 normal volunteers, each of whom ...

journal_title：American heart journal

authors： Nwosu EA,Rahko PS,Hanson P,Grogan EW Jr

更新日期：1994-07-01 00:00:00