Abstract:
BACKGROUND:The purpose of the current study was to determine whether survival after revascularization (coronary artery bypass grafting or percutaneous transluminal coronary angioplasty) is influenced by the extent of electrocardiographic (ECG) evidence of previous myocardial infarction (MI) in patients with ischemic cardiomyopathy by use of the 50-criteria, 31-point Selvester QRS scoring system. METHODS:Patients with ischemic cardiomyopathy documented by a left ventricular ejection fraction (LVEF) < or =30% undergoing coronary angiography between January 1984 and July 1996, with no acute MI within the last 30 days, follow-up through 1996, and > or =75% occlusion in at least 1 major coronary artery at catheterization were included. These patients were subdivided on the basis of subsequent treatment: revascularization or no revascularization. The complete Selvester QRS system was applied to each patient's ECG and the subgroups were further subdivided by QRS score. RESULTS:The 141 patients receiving revascularization had better survival at 5 years compared with the 298 patients receiving no revascularization (adjusted 5-year survival rate 73% vs 47%, P =.0001). No significant treatment differences were observed for low (< or =3 points) versus high (>3 points) QRS levels in either of the 2 treatment groups (revascularized patients: P =.215, patients without revascularization: P =.126) between the 2 treatment groups. Although all patients had LVEF < or =30%, only 8% of patients had QRS scores >10 points, the level that would be expected if the decrease in LVEF could be attributed entirely to infarcted myocardium. CONCLUSIONS:Hibernating myocardium may contribute significantly to the decreased function in patients with ischemic cardiomyopathy, and the QRS score cannot be used as an independent predictor of survival in those patients with a marked decrease in LVEF but small to moderate infarct sizes.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Shah BR,Velazquez E,Shaw LK,Bart B,O'Connor C,Wagner GSdoi
10.1067/mhj.2002.119996subject
Has Abstractpub_date
2002-01-01 00:00:00pages
111-7issue
1eissn
0002-8703issn
1097-6744pii
S0002870302802344journal_volume
143pub_type
杂志文章abstract::Since many patients with chest pain cannot exercise adequately, an alternative stress would be useful to evaluate coronary reserve. We studied the physiologic responses to epinephrine to assess its potential. We report on 39 patients with chest pain. Doses from 0.03 to 0.30 micrograms/kg/min were administered intraven...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(83)90477-5
更新日期:1983-04-01 00:00:00
abstract::There has been skepticism since the early days of open heart surgery that good long-term or even short-term results were possible with repair of pure mitral insufficiency. The authors report 145 patients in whom a markedly insufficient mitral valve was repaired 6 months to 17 years previously and another 55 patients i...
journal_title:American heart journal
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abstract:BACKGROUND:The presence of depression after an acute coronary syndrome (ACS) is associated with worse prognosis and lower adherence to risk-reducing behaviors. We reported earlier that an enhanced depression care intervention reduces depression symptoms and major adverse cardiac events. This study evaluates the impact ...
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更新日期:2012-10-01 00:00:00
abstract::Early postexercise polarcardiographic (PCG) changes in the ST segment vector, as reflected in the variable MS X theta, are reported to clearly distinguish normal subjects from those with myocardial ischemia. We prospectively assessed the value of this test in detecting coronary artery disease (CAD) during treadmill ex...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(85)90019-5
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journal_title:American heart journal
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doi:10.1067/mhj.2002.123110
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abstract::The effects of lorcainide, a new antiarrhythmic drug, on serum electrolytes and osmolality are described in a series of 33 patients with organic heart disease and complex ventricular arrhythmias treated with lorcainide. In eight patients, a mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L was observed after a single 2...
journal_title:American heart journal
pub_type: 杂志文章
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abstract::Fifty adult men with mild to moderate hypertension were recruited to participate in a double-blind crossover study. Each subject received 14 days of drug treatment and 14 days of placebo treatment (random order). Half the subjects were assigned to a metoprolol (150 mg/day) vs placebo treatment regimen and half to an a...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:American heart journal
pub_type: 杂志文章
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journal_title:American heart journal
pub_type: 杂志文章
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90195-n
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:Elevations of creatine kinase-MB (CK-MB) and cardiac troponin T (cTnT) have an uncertain long-term prognostic value after coronary artery bypass graft (CABG) surgery. We aimed to test the hypothesis that CK-MB and cTnT are predictors of long-term survival after CABG and to assess which of these 2 biomarkers ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2012.05.027
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:There are limited data assessing statin therapy in patients with nonobstructive coronary plaque on coronary computed tomography angiography (CCTA). METHODS:Two hundred six consecutive patients with mild noncalcified plaque on CCTA were enrolled in this multicenter prospective observational study. Subjects w...
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pub_type: 杂志文章,多中心研究
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更新日期:2016-10-01 00:00:00
abstract::An expression representative of the rate of change of ventricular power during ejection was derived. The primary advantages of the expression are its theoretical value and its ability to characterize ventricular performance. The rate of change of ventricular power, measured during ejection, is virtually free of assump...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(76)80577-7
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90666-6
更新日期:1991-04-01 00:00:00
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更新日期:2008-10-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(88)90565-0
更新日期:1988-08-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90184-j
更新日期:1991-03-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(93)90929-4
更新日期:1993-09-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2014-10-01 00:00:00
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更新日期:1983-08-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(93)90015-2
更新日期:1993-02-01 00:00:00
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journal_title:American heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:1998-04-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2014.10.011
更新日期:2015-01-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:2009-04-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2009.02.001
更新日期:2009-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.ahj.2005.11.010
更新日期:2006-03-01 00:00:00