Abstract:
:This prospective study evaluated the accuracy of phase analysis of scintigraphic imaging in defining the site of earliest ventricular activation in pediatric patients with electrophysiologic disorders. Twenty patients (10.8 +/- 5.5 years) with preexcitation (n = 16) or ventricular tachycardia (VT) (n = 4) were independently evaluated by phase image analysis and endocardial catheter mapping. The earliest phase angle (contraction), which was common to three scintigraphic imaging planes during preexcited sinus rhythm or VT, was compared with the earliest retrograde atrial activation during reciprocating tachycardia or the origin of VT, as defined by catheter mapping. Phase analysis of earliest contraction was concordant with catheter mapping of electrical activation in all 13 free-wall accessory connections and in three of four patients with VT. Inconclusive definition of activation occurred only in paraseptal accessory connections or VT. In conclusion, phase analysis accurately defines anomalous ventricular activation that is due to free-wall accessory connections or VT. In patients with complex anatomy or small size, phase analysis allows noninvasive localization of the anatomic substrates of tachycardia.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Silka MJ,Chelsky R,Kron J,Wilson RAdoi
10.1016/0002-8703(93)90015-2subject
Has Abstractpub_date
1993-02-01 00:00:00pages
372-80issue
2 Pt 1eissn
0002-8703issn
1097-6744pii
0002-8703(93)90015-2journal_volume
125pub_type
杂志文章abstract::Besides reperfusion treatment, which is the most powerful approach to the underlying pathophysiological cause of myocardial infarction, adjunctive therapies should be considered to reduce clinical symptoms, and improve left ventricular function and mortality rates. Randomized clinical trials and overviews of adjunctiv...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/s0002-8703(99)70341-8
更新日期:1999-08-01 00:00:00
abstract::The short-term hemodynamic effects of molsidomine (4 mg sublingually) were evaluated in 13 patients with congestive heart failure following acute myocardial infarction. Right heart catheterization was performed by means of a Swan-Ganz thermodilution catheter. Hemodynamic measurements were made 30, 60, 120, and 180 min...
journal_title:American heart journal
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::The acute effects of diltiazem on coronary reactive hyperemia were studied in 12 patients with flow-limiting coronary stenosis. Reactive hyperemia was elicited by injection of 8 ml contrast medium into the left coronary artery, while coronary sinus blood flow and left ventricular and aortic pressures were continuously...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(86)90353-4
更新日期:1986-12-01 00:00:00
abstract::Eight patients with multifocal atrial tachycardia received 7 to 12 gm of magnesium sulfate intravenously over a 5-hour period. Potassium supplements were given initially or added later. Initial arterial blood gases showed mean pH 7.48 +/- 0.03, PcO2 39.7 torr, PO2 72 torr, HCO-3 29.8 +/- 4.5 mEq/L, and base excess 6.8...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(85)90458-2
更新日期:1985-10-01 00:00:00
abstract:BACKGROUND:Embolic events to the central nervous system are a major cause of morbidity and mortality in patients with infective endocarditis (IE). The appropriate role of valvular surgery in reducing such embolic events is unclear. The purpose of this study was to determine the relationship between the initiation of an...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2007.07.023
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Patients with diabetes mellitus (DM) experience higher rates of in-stent restenosis and greater benefit from drug-eluting stents implant at the time of percutaneous coronary intervention (PCI), necessitating prolonged dual anti-platelet therapy (DAPT). While DAPT reduces risk of ischemic events post-PCI, it ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2016.09.010
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Standard gray-scale imaging (GSI), three-dimensional (3D) echocardiography has been shown to be superior to two-dimensional echocardiography in measuring left ventricular volume. However, the often relatively poor quality of transthoracic gray-scale data can limit the potential application of this technique....
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(98)70061-4
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Cardiac resynchronization therapy (CRT) improves symptoms, reduces heart failure (HF)-related hospitalizations, and reverses left ventricular remodeling in some patients with moderate to severe HF and ventricular dyssynchrony defined by a prolonged QRS duration. The effects of CRT on HF outcomes in patients ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.03.002
更新日期:2006-02-01 00:00:00
abstract::We compared the pauses that followed the spontaneous termination of supraventricular tachyarrhythmias with the pauses that followed the cessation of atrial overdrive pacing in 21 patients. In 10 patients with abnormal sinus node function and in 11 patients with normal sinus node function we recorded the spontaneous te...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(83)90515-x
更新日期:1983-02-01 00:00:00
abstract::The antiarrhythmic efficacy and safety of intravenous amiodarone were evaluated in 13 patients with recurrent sustained ventricular tachycardia. All patients had been refractory to at least three prior antiarrhythmic agents (mean, 3.3 per patient), and 11 had multiple direct current cardioversions. Intravenous amiodar...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(88)90523-6
更新日期:1988-01-01 00:00:00
abstract::Fingolimod, a sphingosine-1-phosphate receptor (S1PR) modulator, was the first oral disease-modifying therapy approved for relapsing forms of multiple sclerosis; it reduces autoreactive lymphocytes' egress from lymphoid tissues by down-regulating S1PRs. Sphingosine-1-phosphate signaling is implicated in a range of phy...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2014.06.028
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Pacing leads with a small electrode surface for high-impedance stimulation have been shown to prolong pacemaker longevity, but no sufficient data is available on the safety and feasibility of a defibrillation lead with this novel design. METHODS:We evaluated the clinical performance of a tined, steroid-elut...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/S0002-8703(03)00411-3
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:We evaluated ethnic differences in the 10-year risk of myocardial infarction or coronary death derived from Framingham risk equation and in a composite measure of emerging cardiovascular disease risk factors in women and whether statistical adjustments for educational attainment, geographic location, and lif...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.08.027
更新日期:2005-06-01 00:00:00
abstract::The expansion of antiarrhythmic therapy beyond pharmacologic agents to include surgery, devices, and ablation procedures, plus the reaffirmation by the Cardiac Arrhythmia Suppression Trial (CAST) of the need for concurrent placebo-controlled trials to establish a mortality benefit, have resulted in the need to conside...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(94)90097-3
更新日期:1994-04-01 00:00:00
abstract::Thiazides produce an average loss of 2 L of extracellular fluid volume, of which about 300 ml is plasma volume, during the first 48 hours of administration, and this reduction is maintained without further loss for as long as the drug is given. Do thiazides lower blood pressure by volume depletion or by direct vasodil...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(83)90116-3
更新日期:1983-07-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2009.11.009
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Aortopulmonary collaterals (APCs) are frequently observed before and after the Fontan procedure. However, the mechanism of the development of APCs is unknown. We hypothesized that one or several antiangiogenic and/or angiogenic growth factors might play a role in the development of APCs. METHODS:Eighty-five...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2007.03.009
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Prescribing rate control medications with or without antiarrhythmic drugs is often the first course treatment for atrial fibrillation (AF). Clinical trial data suggest that antiarrhythmic drugs are only marginally effective and have multiple drawbacks, whereas rate control alone is sufficient for most patien...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2014.03.024
更新日期:2014-07-01 00:00:00
abstract::Progress in our understanding diabetic angiopathy has been slow, but we are now learning a number of lessons of interest to the cardiologist. Diabetic angiopathy is a collective term for conditions specific to the diabetic state and related to its duration more than to patient age. The angiopathy produces calcificatio...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(78)90053-4
更新日期:1978-09-01 00:00:00
abstract::Atrial antitachycardia pacing was tested in 23 children and young adults. The majority of these patients had had operative repair of congenital cardiac defects and had both bradycardia and tachycardia. Pacemakers were usually implanted by the transvenous technique using bipolar leads. In each patient it was possible t...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90534-o
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND:Coronary heart disease continues to be one of the most common chronic illnesses in the United States and most of the developed world. Clinicians and health authorities have interest in identifying individuals at increased risk of CHD. The Framingham Heart Study has over the years produced mathematical "healt...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2000.96469
更新日期:2000-02-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(99)70486-2
更新日期:1999-03-01 00:00:00
abstract::This study evaluated the efficacy of a comprehensive transthoracic Doppler echocardiographic examination for correct detection of SVA and its associated lesions of VSD and aortic insufficiency. A consecutive series of 36 patients was obtained; all had surgical confirmation of the anatomic defects. The location of the ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(95)90153-1
更新日期:1995-12-01 00:00:00
abstract::Hypertensive cardiovascular risk may be related primarily to vascular overload, the sum of three vascular abnormalities: increased arteriolar resistance, increased large-artery stiffness, and the effect of increased early pulse-wave reflection. A method for quantifying vascular overload as an index can be derived from...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(94)90278-x
更新日期:1994-10-01 00:00:00
abstract::Coronary artery disease remains the leading cause of death in developed countries despite significant progress in primary prevention and treatment strategies. Older patients are at particularly high risk of poor outcomes following acute coronary syndrome and impaired nutrition, including low vitamin D levels, may play...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2013.11.012
更新日期:2014-03-01 00:00:00
abstract::The calcium antagonist, manidipine, was developed on the basis of the hypothesis that antihypertensive drugs that act to improve renal hemodynamic alterations will be therapeutically beneficial in hypertensive patients. Manidipine shows long-lasting calcium channel-blocking action in vascular smooth muscle cells and a...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(93)90203-l
更新日期:1993-02-01 00:00:00
abstract::It has been shown that brief episodes of myocardial ischemia can render the heart more resistant to a prolonged subsequent ischemic episode. This phenomenon, called "preconditioning," has been described in human beings during coronary angioplasty with the use of clinical, electrocardiographic (ECG), or metabolic param...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(97)70200-x
更新日期:1997-04-01 00:00:00
abstract:BACKGROUND:Gastrointestinal bleeding (GIB) after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) and coronary artery disease (CAD) is associated with high morbidity and mortality. METHODS:The NIS database from 1998 to 2006 was used to identify 1,216,759 PCIs performed for ACS and CAD. We sou...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2011.09.009
更新日期:2011-12-01 00:00:00
abstract::With the availability of percutaneous transluminal coronary angioplasty (PTCA), the management of patients who present with recurrent angina following coronary artery bypass surgery (CABG) has changed. From January 1987 to December 1988, 149 symptomatic post CABG patients underwent coronary angiography at our institut...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(90)90121-d
更新日期:1990-11-01 00:00:00
abstract::The efficacy of aspirin to prevent ischemic cardiovascular disease has received considerable attention recently. To determine the prevalence of aspirin use for cardiovascular disease prevention, the Minnesota Heart Survey examined population-based samples of Twin Cities' adults in 1981 to 82 and 1985 to 86. Over the 4...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(88)90344-4
更新日期:1988-09-01 00:00:00