Ethnic differences in cardiovascular risk factor burden among middle-aged women: Study of Women's Health Across the Nation (SWAN).

Abstract:

BACKGROUND:We evaluated ethnic differences in the 10-year risk of myocardial infarction or coronary death derived from Framingham risk equation and in a composite measure of emerging cardiovascular disease risk factors in women and whether statistical adjustments for educational attainment, geographic location, and lifestyle attenuated the magnitude of the ethnic differences in risk. METHODS:Two thousand eight hundred thirty-four premenopausal women free of stroke, heart disease, or diabetes and aged of 42 to 52 years (1400 whites, 729 African American, 226 Hispanic, 231 Chinese, and 248 Japanese) had measurements of blood pressure, lipids and lipoproteins, waist circumference, glucose, insulin, lipoprotein(a), fibrinogen, factor VII, plasminogen activator inhibitor, tissue-type plasminogen activator antigen, and high-sensitivity C-reactive protein. Framingham risk score and number of risk factors in the top quartile of the distribution of risk factors not included in the Framingham score (called composite burden) were calculated. RESULTS:The unadjusted mean values for the two summary scores were higher among African Americans and Hispanics than other groups. Statistical adjustments for education and geographical site accounted for a majority of the ethnic differences, with an additional small effect of lifestyle for the composite burden score. Largest ethnic differences were apparent for waist circumference, lipoprotein(a), high-sensitivity C-reactive protein, and untreated blood pressure. CONCLUSIONS:A substantial part of the risk associated with ethnicity can be attributed to socioeconomic status and geographical location. As the ethnic composition of the United States population becomes more diverse, it is important to appreciate the cardiovascular disease risk factor burden present in some minority groups.

journal_name

Am Heart J

journal_title

American heart journal

authors

Matthews KA,Sowers MF,Derby CA,Stein E,Miracle-McMahill H,Crawford SL,Pasternak RC

doi

10.1016/j.ahj.2004.08.027

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

1066-73

issue

6

eissn

0002-8703

issn

1097-6744

pii

S0002870304005411

journal_volume

149

pub_type

杂志文章
  • Depression and ischemic heart disease.

    abstract::Major depression is a common comorbidity associated with ischemic heart disease (IHD). There is growing evidence that psychological stress in general and depression in particular predispose to cardiovascular disease. Persons who have mental stress during daily life are at twice the risk of myocardial ischemia, and pat...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1067/mhj.2000.109979

    authors: O'connor CM,Gurbel PA,Serebruany VL

    更新日期:2000-10-01 00:00:00

  • Echocardiographic classification of complete atrioventricular canal defects.

    abstract::M-mode echocardiographic records of 26 patients with surgically proven complete atrioventricular canal defect were reviewed. Fragmentation of the interventricular septum and anterior displacement of the mitral annulus into the left ventricular outflow tract were noted in all patients. In 25 of 26 a common atrioventric...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(81)90228-3

    authors: Johnson GL,Twyman RE,Todd EP,Cottrill CM,Noonan JA

    更新日期:1981-05-01 00:00:00

  • Oral blockade of the platelet glycoprotein IIb/IIIa receptor: fact or fancy?

    abstract::Currently available antiplatelet agents are limited in the scope and magnitude of platelet inhibition. Orally active platelet glycoprotein IIb/IIIa antagonists are currently in clinical testing. These agents may extend platelet inhibition and clinical benefit from parenteral glycoprotein IIb/IIIa antagonists. The most...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1053/hj.1999.v138.99080

    authors: Kereiakes DJ

    更新日期:1999-07-01 00:00:00

  • Metabolic risk factors for coronary heart disease in women: perspective from the Framingham Study.

    abstract::In over 30 years of surveillance of 2873 women, 574 developed initial clinical manifestations of CHD. A number of antecedent metabolic risk factors proved atherogenic, including blood lipids, glucose tolerance, uric acid, and menopause. Serum total cholesterol predicts as strongly in women as in men. The predictive po...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(87)90511-4

    authors: Kannel WB

    更新日期:1987-08-01 00:00:00

  • Percutaneous coronary implantation of sirolimus-eluting stents in unselected patients and lesions: clinical results and multiple outcome predictors.

    abstract:BACKGROUND:Sirolimus-eluting stents (SES) prevent restenosis and repeat percutaneous coronary intervention (PCI), but safety data in unselected patients are limited, especially for intermediate-term follow-up. METHODS:All patients undergoing SES implantation at 4 Italian centers were enrolled into a dedicated database...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2008.06.030

    authors: Sangiorgi G,Romagnoli E,Biondi-Zoccai G,Margheri M,Tamburino C,Barbagallo R,Falchetti E,Vittori G,Agostoni P,Cosgrave J,Colombo A,RECIPE (Real-world Eluting-stent Comparative Italian retrosPective Evaluation) Study Investigators.

    更新日期:2008-11-01 00:00:00

  • Segmental wall motion abnormalities in the absence of clinically documented myocardial infarction: clinical significance and evidence of hibernating myocardium.

    abstract::To determine the frequency and significance of left ventricular wall motion abnormalities in patients without clinical evidence of myocardial infarction, we reviewed the two-dimensional echocardiograms of 252 patients who had no history or electrocardiographic evidence of myocardial infarction and who subsequently und...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(91)90666-6

    authors: Lewis SJ,Sawada SG,Ryan T,Segar DS,Armstrong WF,Feigenbaum H

    更新日期:1991-04-01 00:00:00

  • Development and validation of a simple exercise test score for use in women with symptoms of suspected coronary artery disease.

    abstract:BACKGROUND:Recently revised American College of Cardiology/American Heart Association guidelines for exercise electrocardiography (ExECG) have suggested that ExECG scores be used to assist in management decisions in patients with suspected coronary artery disease (CAD). METHODS:We used 442 women who underwent both ExE...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2002.125835

    authors: Morise AP,Lauer MS,Froelicher VF

    更新日期:2002-11-01 00:00:00

  • Effects of recombinant human erythropoietin on platelet activation in acute myocardial infarction: results of a double-blind, placebo-controlled, randomized trial.

    abstract:BACKGROUND:Erythropoietin mitigates myocardial damage and improves ventricular performance after experimental ischemic injury. This study assessed safety and efficacy markers relevant to the biological activity of recombinant human erythropoietin (rHuEpo) in patients with acute myocardial infarction (MI). METHODS:We c...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2009.06.032

    authors: Tang YD,Hasan F,Giordano FJ,Pfau S,Rinder HM,Katz SD

    更新日期:2009-12-01 00:00:00

  • HLA-DR typing and lymphocyte subset evaluation in rheumatic heart disease: a search for immune response factors.

    abstract::Several autoimmune diseases have been associated with increased frequencies of specific histocompatibility (HLA) antigens, particularly for the D (DR) locus, that may be linked to immune response genes. Rheumatic valvular heart disease (RHD) has been postulated to have autoimmune features, but HLA associations have no...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(86)90311-x

    authors: Anastasiou-Nana MI,Anderson JL,Carlquist JF,Nanas JN

    更新日期:1986-11-01 00:00:00

  • Variant angina pectoris: a clinical and coronary arteriographic spectrum.

    abstract::The clinical course and coronary arteriographic findings in eight patients with Prinzmetal's variant angina pectoris are reviewed and contrasted to previously reported cases. In six patients with S-T-elevation inferiorly, three had normal coronary arteriograms, one had complete right coronary artery occlusion, one ha...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(75)90501-3

    authors: Donsky MS,Harris MD,Curry GC,Blomqvist CG,Willerson JT,Mullins CB

    更新日期:1975-05-01 00:00:00

  • Shortcomings of the Lown grading system for observational or experimental studies in ischemic heart disease.

    abstract::The Lown grading system uses three levels of frequency and four complex features to grade ventricular arrhythmias. The seven Lown grades are mutually exclusive (a patient can be in only one grade) and hierarchical (higher grades indicate increased likelihood of death). We evaluated the ability of the Lown arrhythmia g...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(80)90217-3

    authors: Bigger JT Jr,Weld FM

    更新日期:1980-12-01 00:00:00

  • Accuracy and reproducibility of clinically acquired two-dimensional echocardiographic mass measurements.

    abstract::Left ventricular mass (LVM) measurements made by the truncated ellipsoid algorithm from clinical two-dimensional echocardiograms (2DE) were compared to autopsy weights in 37 patients. All six 2DE instruments were calibrated with an ultrasound phantom to standardize LVM measurements. Measurements were made by an experi...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(89)90083-5

    authors: Byrd BF 3rd,Finkbeiner W,Bouchard A,Silverman NH,Schiller NB

    更新日期:1989-07-01 00:00:00

  • Prognostic significance of the Karnofsky Performance Status score in patients with acute myocardial infarction: comparison with the left ventricular ejection fraction and the exercise treadmill test performance. The MILIS Study Group.

    abstract::The prognostic significance of functional status has not been previously studied in the setting of acute myocardial infarction. We assessed the Karnofsky Performance Status (KPS) score, a simple functional status scale that is commonly used to categorize physical ability, in 849 patients with acute myocardial infarcti...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/0002-8703(91)90141-4

    authors: Brezinski D,Stone PH,Muller JE,Tofler GH,Davis V,Parker C,Hartley LH,Braunwald E

    更新日期:1991-05-01 00:00:00

  • A simple bedside test of 1-minute heart rate variability during deep breathing as a prognostic index after myocardial infarction.

    abstract:BACKGROUND:We evaluate a simple, bedside test that measures 1-minute heart rate variability in deep breathing as a predictor of death after myocardial infarction. METHODS:Bedside heart rate variability was assessed in 185 consecutive patients 5.1 +/- 2.5 days after a first myocardial infarction. Patients were instruct...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(99)70242-5

    authors: Katz A,Liberty IF,Porath A,Ovsyshcher I,Prystowsky EN

    更新日期:1999-07-01 00:00:00

  • Short- and long-term changes in myocardial function, morphology, edema, and infarct mass after ST-segment elevation myocardial infarction evaluated by serial magnetic resonance imaging.

    abstract:BACKGROUND:Knowledge of the natural course after an ST-elevation myocardial infarction (STEMI) treated according to guidelines is limited because comprehensive serial magnetic resonance imaging (MRI) of systolic left ventricular function, edema, perfusion, and infarct size after STEMI has not been undertaken. The aim o...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2007.06.038

    authors: Ripa RS,Nilsson JC,Wang Y,Søndergaard L,Jørgensen E,Kastrup J

    更新日期:2007-11-01 00:00:00

  • Predictors of response to cardiac resynchronization therapy (PROSPECT)--study design.

    abstract:BACKGROUND:Cardiac resynchronization therapy (CRT) is currently indicated in patients with moderate to severe heart failure, a wide QRS complex and significant left ventricular dysfunction despite optimal medical therapy. Adoption of these criteria for CRT results in a favorable response in only two thirds of candidate...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2004.12.013

    authors: Yu CM,Abraham WT,Bax J,Chung E,Fedewa M,Ghio S,Leclercq C,León AR,Merlino J,Nihoyannopoulos P,Notabartolo D,Sun JP,Tavazzi L,PROSPECT Investigators.

    更新日期:2005-04-01 00:00:00

  • Outcomes and cost among Medicare beneficiaries hospitalized for heart failure assigned to accountable care organizations.

    abstract::Little is known about the impact of accountable care organizations (ACO) on hospitalized heart failure (HF) patients, a high-cost and high-risk population. OBJECTIVE:We linked Medicare fee-for-service claims from 2013 to 2015 with data from American Heart Association Get With The Guidelines-HF registry to compare HF ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2020.04.028

    authors: Luo N,Hammill BG,DeVore AD,Xu H,Fonarow GC,Albert NM,Matsouaka RA,Hernandez AF,Yancy C,Mentz RJ

    更新日期:2020-08-01 00:00:00

  • Incidence of severe renal dysfunction among individuals taking warfarin and implications for non-vitamin K oral anticoagulants.

    abstract:BACKGROUND:The purpose of this study is to assess incidence and risk factors for severe renal dysfunction in patients requiring oral anticoagulation to help guide initial drug choice and provide a rational basis for interval monitoring of renal function for patients prescribed non-vitamin K oral anticoagulants. METHOD...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2016.08.017

    authors: Fanola CL,Mooney D,Cowan AJ,Ko D,Sisson EK,Henault LE,Tripodis Y,Hylek EM

    更新日期:2017-02-01 00:00:00

  • Recent trends in the incidence rates of and death rates from atrial fibrillation complicating initial acute myocardial infarction: a community-wide perspective.

    abstract:BACKGROUND:Limited information is available about recent trends in the incidence and death rates from atrial fibrillation (AF) complicating acute myocardial infarction (AMI). The purpose of this study was to examine the impact and trends over time of AF complicating initial AMI. METHODS:We conducted a longitudinal stu...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1067/mhj.2002.120410

    authors: Goldberg RJ,Yarzebski J,Lessard D,Wu J,Gore JM

    更新日期:2002-03-01 00:00:00

  • The effects of exercise on cardiovascular biomarkers in patients with chronic heart failure.

    abstract:BACKGROUND:Exercise training is recommended for chronic heart failure (HF) patients to improve functional status and reduce risk of adverse outcomes. Elevated plasma levels of amino-terminal pro-brain natriuretic peptide (NT-proBNP), high-sensitivity C-reactive protein (hs-CRP), and cardiac troponin T (cTnT) are associ...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2013.10.018

    authors: Ahmad T,Fiuzat M,Mark DB,Neely B,Neely M,Kraus WE,Kitzman DW,Whellan DJ,Donahue M,Zannad F,Piña IL,Adams K,O'Connor CM,Felker GM

    更新日期:2014-02-01 00:00:00

  • Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS)--study design.

    abstract:BACKGROUND AND OBJECTIVE:Embolization of atherothrombotic material is common during percutaneous coronary intervention (PCI) in acute myocardial infarction (MI). This may lead to distal vessel occlusion resulting in impaired myocardial perfusion, which is associated with larger infarct size and increased mortality. Adj...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2005.11.010

    authors: Svilaas T,van der Horst IC,Zijlstra F

    更新日期:2006-03-01 00:00:00

  • Diet and incident venous thromboembolism: the Iowa Women's Health Study.

    abstract:BACKGROUND:Little is known about the role of diet in the development of venous thromboembolism (VTE). We explored the prospective relation of dietary patterns, food groups, and nutrients to incident VTE in older women. METHODS:In 1986, Iowa women aged 55 to 69 years completed a mailed survey, including a 127-item food...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2009.04.003

    authors: Lutsey PL,Steffen LM,Virnig BA,Folsom AR

    更新日期:2009-06-01 00:00:00

  • Left ventricular ejection fraction to predict early mortality in patients with non-ST-segment elevation acute coronary syndromes.

    abstract:BACKGROUND:Improvement in risk stratification of patients with non-ST-segment elevation acute coronary syndrome (ACS) is a gateway to a more judicious treatment. This study examines whether the routine determination of left ventricular ejection fraction (EF) adds significant prognostic information to currently recommen...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2004.09.027

    authors: Bosch X,Théroux P

    更新日期:2005-08-01 00:00:00

  • Use and long-term outcomes of implantable cardioverter-defibrillators, 1990 to 2009.

    abstract:BACKGROUND:Automated implantable cardioverter-defibrillators (ICDs) have become standard therapy for patients at high risk for sudden cardiac death. Linked data allow examination of trends in use and long-term survival after ICD implantation in an adult population. METHODS:Linked state-wide person-based data on hospit...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2013.02.007

    authors: Bradshaw PJ,Stobie P,Briffa T,Hobbs MS

    更新日期:2013-05-01 00:00:00

  • Benefits of lipid lowering on vascular reactivity in patients with coronary artery disease and average cholesterol levels: a mechanism for reducing clinical events?

    abstract:BACKGROUND:The favorable effects of lowering low-density lipoprotein (LDL)-cholesterol on reducing clinical events in patients with coronary disease have been well established. The mechanisms responsible for this benefit, however, have not been fully understood. This study examined the impact of lipid-lowering therapy ...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0002-8703(00)90057-7

    authors: Cohen JD,Drury JH,Ostdiek J,Finn J,Babu BR,Flaker G,Belew K,Donohue T,Labovitz A

    更新日期:2000-04-01 00:00:00

  • Mid-cavity obstruction in apical hypertrophy: Doppler evidence of diastolic intraventricular gradient with higher apical pressure.

    abstract::Three cases of apical left ventricular hypertrophy demonstrating a sequestered small left ventricular apical cavity with complete systolic and partial diastolic intraventricular obstruction are described. Doppler studies revealed that flow from the apical chamber is aborted during early systole with further emptying d...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(88)90730-2

    authors: Zoghbi WA,Haichin RN,Quinones MA

    更新日期:1988-12-01 00:00:00

  • Mode of stimulation versus response: validation of a protocol for induction of ventricular tachycardia.

    abstract::Electrophysiologic studies were prospectively performed in 91 consecutive patients referred for evaluation of sustained ventricular tachycardia or sudden cardiac death. Fifty-two patients had a history of sustained ventricular tachycardia and 39 patients had a history of sudden cardiac death. The identical stimulation...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(85)90088-2

    authors: Oseran DS,Gang ES,Hamer AW,Zaher CA,Rosenthal ME,Mandel WJ,Peter T

    更新日期:1985-09-01 00:00:00

  • Sudden death and silent myocardial ischemia.

    abstract::Recent research indicates that silent myocardial ischemia may play a role in sudden cardiac death. To what extent treatment can reduce occurrence of silent ischemia remains to be assessed. Three classes of silent ischemia patients are identified: type 1--totally asymptomatic; type 2--post myocardial infarction; and ty...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(89)90673-x

    authors: Sheps DS,Heiss G

    更新日期:1989-01-01 00:00:00

  • Pulmonary valve annulus grows after balloon dilatation of neonatal critical pulmonary valve stenosis.

    abstract:BACKGROUND:Neonates with critical pulmonary valve stenosis often demonstrate small or hypoplastic right ventricular structures. Relief of the obstruction enhances forward flow across the right ventricle and reduces its pressure load. Growth of the right ventricle and especially of the pulmonary valve annulus was evalua...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1053/hj.1998.v136.89576

    authors: Gildein HP,Kleinert S,Goh TH,Wilkinson JL

    更新日期:1998-08-01 00:00:00

  • Phosphodiesterase III inhibition or adrenoreceptor stimulation: milrinone as an alternative to dobutamine in the treatment of severe heart failure.

    abstract::High levels of endogenous plasma catecholamines in patients with severe congestive heart failure induce a down-regulation of the myocardial beta-adrenoreceptors and thus cause adrenoreceptor agonists, such as dobutamine, to be less effective in the treatment of these patients. Phosphodiesterase III inhibitors work ind...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-8703(91)90834-5

    authors: Mager G,Klocke RK,Kux A,Höpp HW,Hilger HH

    更新日期:1991-06-01 00:00:00