Mid-cavity obstruction in apical hypertrophy: Doppler evidence of diastolic intraventricular gradient with higher apical pressure.

Abstract:

:Three cases of apical left ventricular hypertrophy demonstrating a sequestered small left ventricular apical cavity with complete systolic and partial diastolic intraventricular obstruction are described. Doppler studies revealed that flow from the apical chamber is aborted during early systole with further emptying during diastole through a narrow intraventricular channel, where a diastolic high-velocity jet (greater than or equal to 2.5 m/sec) directed from apex to base was localized. This indicated a significantly higher pressure in early diastole in the sequestered apical cavity. Filling of the apical chamber occurred late in diastole and during isovolumic ventricular contraction. The observations by Doppler of complete intraventricular systolic and partial diastolic obstruction in apical hypertrophy are new and may have significant clinical implications.

journal_name

Am Heart J

journal_title

American heart journal

authors

Zoghbi WA,Haichin RN,Quinones MA

doi

10.1016/0002-8703(88)90730-2

subject

Has Abstract

pub_date

1988-12-01 00:00:00

pages

1469-74

issue

6 Pt 1

eissn

0002-8703

issn

1097-6744

pii

0002-8703(88)90730-2

journal_volume

116

pub_type

杂志文章
  • Race and ethnicity influences on cardiovascular and renal events in patients with diabetes mellitus.

    abstract:BACKGROUND:The incidence of end-stage renal disease (ESRD) has been consistently shown to be higher among blacks and Hispanics compared to whites with unmeasured risk factors and access to care as suggested explanations. In a high-risk cohort with frequent protocol-directed follow-up, we evaluated the influence of race...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2015.05.008

    authors: Lewis EF,Claggett B,Parfrey PS,Burdmann EA,McMurray JJ,Solomon SD,Levey AS,Ivanovich P,Eckardt KU,Kewalramani R,Toto R,Pfeffer MA

    更新日期:2015-08-01 00:00:00

  • Effectiveness of recanalization of chronic total occlusions: a systematic review and meta-analysis.

    abstract:BACKGROUND:Chronic total occlusion (CTO) recanalizations remain extremely challenging procedures. With improvements in technology and techniques, success rates for recanalization of CTO continue to improve. However, the clinical benefits of this practice remain unclear. The aim of the study was to determine the effecti...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ahj.2010.04.015

    authors: Joyal D,Afilalo J,Rinfret S

    更新日期:2010-07-01 00:00:00

  • Cardiac biomarker measurement after elective percutaneous coronary interventions in older patients: insights from the National Cardiovascular Data Registry.

    abstract:BACKGROUND:Guidelines recommend consideration of cardiac biomarker measurement after elective percutaneous coronary intervention (PCI), especially with complex cases or complicated procedures. However, the long-term prognostic implications of biomarker measurement after elective PCI have not been well characterized in ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2013.09.007

    authors: Wang TY,McCoy LA,Messenger JC,Neely ML,Ho KK,Roe MT,Anderson HV

    更新日期:2013-11-01 00:00:00

  • Prediction of survival in progressive systemic sclerosis by multivariate analysis of clinical features.

    abstract::The records of 64 patients with progressive systemic sclerosis (PSS) were reviewed. More than 100 items from the patient's history, physical examination, and laboratory tests were encoded. A two-tailed Gehan's test was used to evaluate the effect of each variable on patient survival. Variables significant at the 0.05 ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(85)90525-3

    authors: Wynn J,Fineberg N,Matzer L,Cortada X,Armstrong W,Dillon JC,Kinney EL

    更新日期:1985-07-01 00:00:00

  • Cardiac function and cardiac events 1-year postpartum in women with congenital heart disease.

    abstract:BACKGROUND:Pregnancy is increasingly common in women with congenital heart disease (CHD), but little is known about long-term cardiovascular outcome after pregnancy in these patients. We studied the incidence of cardiovascular events 1-year postpartum and compared cardiac function prepregnancy and 1-year postpartum in ...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2014.11.010

    authors: Kampman MA,Balci A,Groen H,van Dijk AP,Roos-Hesselink JW,van Melle JP,Sollie-Szarynska KM,Wajon EM,Mulder BJ,van Veldhuisen DJ,Pieper PG,ZAHARA II investigators.

    更新日期:2015-02-01 00:00:00

  • Usefulness of the VerifyNow P2Y12 assay to evaluate the antiplatelet effects of ticagrelor and clopidogrel therapies.

    abstract:OBJECTIVES:We analyzed the antiplatelet effects of different P2Y(12) receptor blockers with VerifyNow P2Y12 assay (VN-P2Y12) and light transmittance aggregometry (LTA). BACKGROUND:The point-of-care VN-P2Y12 has been used to assess the antiplatelet effects in clopidogrel-treated patients but has not been evaluated in d...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2012.03.022

    authors: Jeong YH,Bliden KP,Antonino MJ,Park KS,Tantry US,Gurbel PA

    更新日期:2012-07-01 00:00:00

  • Effect of variability in the interpretation of coronary angiograms on the appropriateness of use of coronary revascularization procedures.

    abstract:BACKGROUND:Evidence from numerous studies of coronary angiography show differences between observers' assessments of 15% to 45%. The implication of this variation is serious: If readings are erroneous, some patients will undergo revascularization procedures unnecessarily and others will be denied an essential treatment...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0002-8703(00)90316-8

    authors: Leape LL,Park RE,Bashore TM,Harrison JK,Davidson CJ,Brook RH

    更新日期:2000-01-01 00:00:00

  • A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting.

    abstract:BACKGROUND:Anginal chest pain without creatine kinase (CK) elevation is frequently observed in the first hours after coronary stenting. Possible causes of ischemic episodes are microembolism, side branch occlusion, coronary vasospasm, and disturbances of microvascular circulation. In a prospective, double-blind, random...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-8703(00)90306-5

    authors: Kurz DJ,Naegeli B,Bertel O

    更新日期:2000-01-01 00:00:00

  • Radionuclide angiographic evaluation of left ventricular performance at rest and during exercise in patients with aortic regurgitation.

    abstract::Radionuclide angiographic evaluation of LV performance at rest and during exercise in patients with AR have shown that an abnormal EF response to exercise may be observed in asymptomatic patients with normal resting LV function. The EF response to exercise has been correlated with a number of clinical and exercise mea...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(86)90019-0

    authors: Iskandrian AS,Heo J

    更新日期:1986-06-01 00:00:00

  • Effects of the thromboxane synthetase inhibitor and receptor antagonist terbogrel in patients with primary pulmonary hypertension.

    abstract:BACKGROUND:Circulating mediators, including thromboxane A2, the vasoconstrictor, platelet aggregant, and smooth muscle mitogen, may contribute to the progression of vascular narrowing in primary pulmonary hypertension (PPH). METHODS:To further understand the contribution of thromboxane and to provide novel therapy for...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1067/mhj.2002.121806

    authors: Langleben D,Christman BW,Barst RJ,Dias VC,Galiè N,Higenbottam TW,Kneussl M,Korducki L,Naeije R,Riedel A,Simonneau G,Hirsch AM,Rich S,Robbins IM,Oudiz R,McGoon MD,Badesch DB,Levy RD,Mehta S,Seeger W,Solèr M

    更新日期:2002-05-01 00:00:00

  • Cocaine use is associated with an increased risk of stent thrombosis after percutaneous coronary intervention.

    abstract:BACKGROUND:The treatment of cocaine-related acute coronary syndromes presents unique challenges. Although percutaneous coronary intervention in cocaine abusers appears to be safe in the short term, longer-term outcomes have not been reported. We postulated that cocaine use would be associated with increased risk for st...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2007.04.004

    authors: McKee SA,Applegate RJ,Hoyle JR,Sacrinty MT,Kutcher MA,Sane DC

    更新日期:2007-07-01 00:00:00

  • Quantitative Blush Evaluator accurately quantifies microvascular dysfunction in patients with ST-elevation myocardial infarction: comparison with cardiovascular magnetic resonance.

    abstract:BACKGROUND:After ST-elevation myocardial infarction (STEMI), microvascular obstruction (MVO) can be assessed using semiquantitative angiographic "blush" scores subject to interoperator variability. Quantitative Blush Evaluator (QuBE) is a free computer-calculated algorithm that evaluates myocardial blush on a continuou...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2011.04.014

    authors: Porto I,Hamilton-Craig C,De Maria GL,Vergallo R,Cautilli G,Galiuto L,Burzotta F,Leone AM,Niccoli G,Natale L,Bonomo L,Crea F

    更新日期:2011-08-01 00:00:00

  • Effect of intravenous metoprolol before hospital admission on chest pain in suspected acute myocardial infarction.

    abstract:BACKGROUND:The aim of this study was to describe the effect of intravenous metoprolol on the intensity of chest pain before hospital admission in patients with suspected acute myocardial infarction AMI). METHODS AND RESULTS:Two hundred sixty-two patients with acute chest pain and suspected AMI were randomly assigned b...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-8703(99)70405-9

    authors: Gardtman M,Dellborg M,Brunnhage C,Lindkvist J,Waagstein L,Herlitz J

    更新日期:1999-05-01 00:00:00

  • Transseptal left heart catheterization with a Swan-Ganz flow-directed catheter: review of 173 studies.

    abstract::Of 178 transseptal left heart catheterizations performed, 173 successful cases are reported, with the use of a Swan-Ganz, flow-directed, balloon-tipped catheter. By means of a modified Brockenbrough technique, which is described in detail, a 10F Teflon tube (3.3 mm outside diameter) was inserted into the left atrium. ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(85)90603-9

    authors: Bagger JP,Sennels F,Vejby-Christensen H,Rasmussen K,Thomsen PE,Gøtzsche H

    更新日期:1985-02-01 00:00:00

  • Survival of DDD pacing mode after atrioventricular junction ablation and pacing for refractory atrial fibrillation.

    abstract:BACKGROUND:Patients with recurrent forms of atrial fibrillation may receive dual-chamber pacemakers after atrioventricular junction ablation for refractory symptoms. These patients are at risk for chronic atrial fibrillation, which would negate the benefits of dual-chamber pacing. The purpose of this study was to exami...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s0002-8703(99)70223-1

    authors: Wood MA,Curtis AB,Takle-Newhouse TA,Ellenbogen KA

    更新日期:1999-04-01 00:00:00

  • Primary and subsequent coronary risk appraisal: new results from the Framingham study.

    abstract:BACKGROUND:Coronary heart disease continues to be one of the most common chronic illnesses in the United States and most of the developed world. Clinicians and health authorities have interest in identifying individuals at increased risk of CHD. The Framingham Heart Study has over the years produced mathematical "healt...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2000.96469

    authors: D'Agostino RB,Russell MW,Huse DM,Ellison RC,Silbershatz H,Wilson PW,Hartz SC

    更新日期:2000-02-01 00:00:00

  • Atrial T(Ta) wave and atrial gradient in patients with A-V block.

    abstract::The P and the Ta waves of two patient groups with A-V block were magnified with a direct-current amplifier and recorded at a high paper speed. In Group A patients (those without serious cardiovascular complications except A-V block) the P and the Ta waves were recorded in the opposite direction in every lead and there...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(76)80533-9

    authors: Hayashi H,Okajima M,Yamada K

    更新日期:1976-06-01 00:00:00

  • Prognostic implications of creatine kinase-MB measurements in ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention.

    abstract:BACKGROUND:Peak creatine kinase (CK)-MB concentration is related to reperfusion success and clinical outcomes after fibrinolytic therapy for acute myocardial infarction. However, prognostic implications of CK-MB measurements after primary percutaneous coronary intervention (PCI), which provides more predictable and con...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2014.06.008

    authors: Bagai A,Schulte PJ,Granger CB,Mahaffey KW,Christenson RH,Bell G,Lopes RD,Green CL,Lincoff AM,Armstrong PW,Roe MT

    更新日期:2014-10-01 00:00:00

  • Kidney function and anemia as risk factors for coronary heart disease and mortality: the Atherosclerosis Risk in Communities (ARIC) Study.

    abstract:BACKGROUND:Kidney failure causes anemia and is associated with a very high risk of coronary heart disease (CHD). Mildly to moderately decreased kidney function is far more common and also is associated with an elevated prevalence of anemia and CHD risk. Recent data suggest an even higher risk of CHD when both condition...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2005.03.055

    authors: Astor BC,Coresh J,Heiss G,Pettitt D,Sarnak MJ

    更新日期:2006-02-01 00:00:00

  • Predicting significant coronary artery disease in patients with left ventricular dysfunction.

    abstract:BACKGROUND:Because coronary artery disease (CAD) is a prevalent comorbidity in patients with low ejection function (EF), a number of patients with heart failure undergo diagnostic cardiac catheterization. The objective of this study was to develop a model to assist clinicians in determining the likelihood of CAD before...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2005.12.001

    authors: Whellan DJ,Tuttle RH,Velazquez EJ,Shaw LK,Jollis JG,Ellis W,O'Connor CM,Califf RM,Borges-Neto S

    更新日期:2006-08-01 00:00:00

  • A randomized, placebo-controlled trial of early eptifibatide for non-ST-segment elevation acute coronary syndromes.

    abstract:BACKGROUND:The acute benefits of platelet glycoprotein IIb/IIIa inhibitors for non-ST-segment elevation acute coronary syndromes (NSTE ACS) remain unclear. METHODS:In this pilot trial, 311 patients with NSTE ACS were randomly assigned in the emergency department to double-blinded therapy with eptifibatide or placebo f...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/S0002-8703(03)00517-9

    authors: Roe MT,Christenson RH,Ohman EM,Bahr R,Fesmire FM,Storrow A,Mollod M,Peacock WF,Rosenblatt JA,Yang H,Fraulo ES,Hoekstra JW,Gibler WB,EARLY Investigators.,Emergency Medicine Cardiac Research and Education Group.

    更新日期:2003-12-01 00:00:00

  • Effects of aging on left ventricular structure and function.

    abstract::To better characterize the cardiac structural and functional changes that are associated with aging, Doppler-echocardiography was performed on 23 young (mean age, 25 years) and 30 old (mean age, 70 years) healthy normotensive subjects. Left ventricular cavity dimensions and wall thickness were determined and left vent...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(91)90201-r

    authors: Pearson AC,Gudipati CV,Labovitz AJ

    更新日期:1991-03-01 00:00:00

  • Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes.

    abstract:BACKGROUND:Coronary artery disease (CAD) and, increasingly, diabetes are recognized as having an inflammatory basis. Membrane toll-like receptors (TLRs) activate signaling pathways that up-regulate inflammation. We evaluated whether the Asp299Gly polymorphism in the TLR4 gene, which impairs inflammatory responses, is a...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2004.05.049

    authors: Kolek MJ,Carlquist JF,Muhlestein JB,Whiting BM,Horne BD,Bair TL,Anderson JL

    更新日期:2004-12-01 00:00:00

  • Meta-analysis: inhibition of renin-angiotensin system prevents new-onset atrial fibrillation.

    abstract:BACKGROUND:Epidemiologic studies suggest that inhibition of renin-angiotensin system with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may prevent development of atrial fibrillation (AF). OBJECTIVE:The objective of the study was to assess if there is significant indication for using angio...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.ahj.2006.01.007

    authors: Anand K,Mooss AN,Hee TT,Mohiuddin SM

    更新日期:2006-08-01 00:00:00

  • Application of noninvasive techniques for measuring cardiac output in hypertensive patients.

    abstract::The hemodynamic hallmark of hypertension is increased systemic vascular resistance, although this variable is usually not determined in hypertensive patients because it has generally required invasive procedures to measure cardiac output. Reliable, totally noninvasive methods are now available that measure cardiac out...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/0002-8703(88)90565-0

    authors: Franciosa JA

    更新日期:1988-08-01 00:00:00

  • Impact of smoking on antiplatelet effect of clopidogrel and prasugrel after loading dose and on maintenance therapy.

    abstract:BACKGROUND:Pharmacodynamic studies reported an amplified on-clopidogrel platelet inhibition in smokers potentially caused by an increased metabolic drug activation via induction of cytochrome P450 1A2. The aims of this analysis were to evaluate the impact of smoking on the antiplatelet effect of clopidogrel and prasugr...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2011.06.005

    authors: Hochholzer W,Trenk D,Mega JL,Morath T,Stratz C,Valina CM,O'Donoghue ML,Bernlochner I,Contant CF,Guo J,Sabatine MS,Schömig A,Neumann FJ,Kastrati A,Wiviott SD,Sibbing D

    更新日期:2011-09-01 00:00:00

  • M-mode echocardiography in left bundle branch block: significance of frontal plane QRS axis.

    abstract::M-mode echocardiograms were obtained in 48 patients with complete left bundle branch block (LBBB). Of these 48 patients, 28 had LBBB with normal frontal plane QRS axis (-20 degrees to +90 degrees, mean +/- SD 18 degrees +/- 34 degrees), and 20 had LBBB with a left axis deviation (LAD) (-30 degrees to -60 degrees, mean...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(82)90010-2

    authors: Strasberg B,Rich S,Lam W,Swiryn S,Bauernfeind R,Rosen KM

    更新日期:1982-10-01 00:00:00

  • Echocardiographic classification of complete atrioventricular canal defects.

    abstract::M-mode echocardiographic records of 26 patients with surgically proven complete atrioventricular canal defect were reviewed. Fragmentation of the interventricular septum and anterior displacement of the mitral annulus into the left ventricular outflow tract were noted in all patients. In 25 of 26 a common atrioventric...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(81)90228-3

    authors: Johnson GL,Twyman RE,Todd EP,Cottrill CM,Noonan JA

    更新日期:1981-05-01 00:00:00

  • Trends in the pharmacologic management of atrial fibrillation: Data from the Veterans Affairs health system.

    abstract:BACKGROUND:Prescribing rate control medications with or without antiarrhythmic drugs is often the first course treatment for atrial fibrillation (AF). Clinical trial data suggest that antiarrhythmic drugs are only marginally effective and have multiple drawbacks, whereas rate control alone is sufficient for most patien...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2014.03.024

    authors: Vaughan-Sarrazin MS,Mazur A,Chrischilles E,Cram P

    更新日期:2014-07-01 00:00:00

  • Ancrod decreases the frequency of cyclic flow variations and causes thrombolysis following acute coronary thrombosis.

    abstract::The potential use of ancrod, a purified isolate from the venom of the Malaysian pit viper, Agkistrodon rhodostoma, in decreasing the frequency of cyclic flow variations in severely stenosed canine coronary arteries and causing thrombolysis of an acute coronary thrombus induced by a copper coil was evaluated. Open-ches...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(87)90050-0

    authors: Apprill PG,Ashton J,Guerrero J,Glas-Greenwalt P,Buja LM,Willerson JT

    更新日期:1987-04-01 00:00:00