Oral blockade of the platelet glycoprotein IIb/IIIa receptor: fact or fancy?

abstract：BACKGROUND:Although outcomes data on transcatheter aortic valve replacement (TAVR) and transcatheter mitral valve repair (Mitraclip) are available via the Transcatheter Valve Therapy (TVT) registry, dissemination of TVT data is often delayed. The Food and Drug Administration's Manufacturer and User Facility Device Expe...

journal_title：American heart journal

authors： Galper BZ,Beery DE,Leighton G,Englander LL

更新日期：2018-04-01 00:00:00

abstract：:An optimal method for determining left ventricular ejection fraction (LVEF) by echocardiography should be rapid, reliable, and widely applicable in order to be utilized routinely in a busy clinical laboratory. Most methods reported in the literature are reliable in selected, high-quality echocardiograms. Most require ...

journal_title：American heart journal

authors： Amico AF,Lichtenberg GS,Reisner SA,Stone CK,Schwartz RG,Meltzer RS

更新日期：1989-12-01 00:00:00

abstract：:The effects of nadolol (N) and propranolol (P) were studied in atrial and ventricular tachyarrhythmias. Interpretation of the results should take into account the dependence of the arrhythmia on the sympathetic tone, and the drug effect on the sinus node frequency. The day/night ratio of the sinus rate is too sensitiv...

journal_title：American heart journal

authors： Coumel P,Escoubet B,Attuel P

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Plasma levels of brain natriuretic peptide (BNP) are increased in patients with left heart failure. In patients with severe pulmonary embolism (PE), primary right ventricular (RV) dysfunction is frequent. Little is known about BNP secretion in acute RV failure. METHODS:We prospectively studied 50 consecutiv...

journal_title：American heart journal

authors： Krüger S,Graf J,Merx MW,Koch KC,Kunz D,Hanrath P,Janssens U

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Recent work has demonstrated a link between retinopathy, a marker of microvascular disease, and the development of heart failure, a finding particularly relevant in individuals with diabetes. Our objective was to assess the relationship between retinopathy and cardiac structure and function in a cohort of in...

journal_title：American heart journal

authors： Aguilar D,Hallman DM,Piller LB,Klein BE,Klein R,Devereux RB,Arnett DK,Gonzalez VH,Hanis CL

更新日期：2009-03-01 00:00:00

abstract：:The acute hemodynamic and electrophysiologic effects of flecainide in tachycardia-induced ventricular dysfunction were investigated using an animal model. Seven swine were initially (CON) evaluated by echocardiography and then by right heart catheterization and provocative electrical ventricular stimulation both befor...

journal_title：American heart journal

authors： Trippel DL,Harold ME,Spinale FG,Buckles DS,Gillette PC

更新日期：1991-06-01 00:00:00

abstract：:The antihypertensive efficacy, safety, and lipid effects of doxazosin, a selective alpha 1-inhibitor, were assessed in a general practice setting. Three hundred twenty-six patients were entered into the study, which involved three phases: (1) a 2-week baseline period, (2) an 8-week period in which patients received 1 ...

journal_title：American heart journal

authors： Naber FB

更新日期：1991-01-01 00:00:00

abstract：:M-mode echocardiograms were obtained in 48 patients with complete left bundle branch block (LBBB). Of these 48 patients, 28 had LBBB with normal frontal plane QRS axis (-20 degrees to +90 degrees, mean +/- SD 18 degrees +/- 34 degrees), and 20 had LBBB with a left axis deviation (LAD) (-30 degrees to -60 degrees, mean...

journal_title：American heart journal

authors： Strasberg B,Rich S,Lam W,Swiryn S,Bauernfeind R,Rosen KM

更新日期：1982-10-01 00:00:00

abstract：:Percutaneous transluminal coronary recanalization, a new therapeutic procedure used in acute myocardial infarction, offers significant reduction in mortality, as well as more effective limitation of the zone of infarction than has been possible with other pharmacologic treatment employed in the past. The risk of coron...

journal_title：American heart journal

authors： Rutsch W,Schartl M,Mathey D,Kuck K,Merx W,Dörr R,Rentrop P,Blanke H

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Preoperative use of angiotensin-blocking drug therapy (ABDT) with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and its link to occurrence of postoperative atrial fibrillation (POAF), a common marker of poor outcomes after cardiac surgery, remain controversial. METHODS:From 19...

journal_title：American heart journal

authors： Rader F,Van Wagoner DR,Gillinov AM,Blackstone EH

更新日期：2010-08-01 00:00:00

abstract：:Early postexercise polarcardiographic (PCG) changes in the ST segment vector, as reflected in the variable MS X theta, are reported to clearly distinguish normal subjects from those with myocardial ischemia. We prospectively assessed the value of this test in detecting coronary artery disease (CAD) during treadmill ex...

journal_title：American heart journal

authors： Lam JC,Chaitman BR,Hanson JS,Bernard P,Bourassa MG

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) ablation is superior to pharmacologic therapy in achieving maintenance of normal sinus rhythm in selected patient populations. However, the procedure is resource intensive, and repeat ablations are sometimes required. We examined the predictors and trends of repeat ablation using a l...

journal_title：American heart journal

authors： Al-Hijji MA,Deshmukh AJ,Yao X,Mwangi R,Sangaralingham LR,Friedman PA,Asirvatham SJ,Packer DL,Shah ND,Noseworthy PA

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:In the treatment of coronary artery disease, a "pro-healing" approach for prevention of in-stent restenosis and late stent thrombosis is intuitively favored over the use of cytotoxic or cytostatic drugs released from a drug-eluting stent (DES). Promoting accelerated endothelial coverage of the stent surface,...

journal_title：American heart journal

authors： Klomp M,Beijk MA,Verouden NJ,Tijssen JG,de Winter RJ,TRIAS Investigators.

更新日期：2009-10-01 00:00:00

abstract：:Reperfusion therapy has lowered the mortality in patients suffering acute myocardial infarction. Failure to reperfuse is associated with significantly higher risk of short- and long-term mortality. Detection of reperfusion is thus important. In a prospective pilot study, we used continuous on-line computerized vectorc...

journal_title：American heart journal

authors： Dellborg M,Topol EJ,Swedberg K

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to estimate the cost-effectiveness of beta-blocker therapy with either metoprolol or carvedilol in addition to conventional therapy for patients with heart failure (HF) in Canada. DESIGN:A Markov simulation was used to estimate the costs and life expectancy for treating patients...

journal_title：American heart journal

authors： Levy AR,Briggs AH,Demers C,O'Brien BJ

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:The relationship of changes in weight to outcomes in patients after myocardial infarction (MI) is controversial. METHODS:From the ENRICHD trial data, we assessed weight change, and the associations of baseline weight and change at follow-up with outcomes and interactions between psychosocial factors. RESUL...

journal_title：American heart journal

authors： Lopez-Jimenez F,Wu CO,Tian X,O'Connor C,Rich MW,Burg MM,Sheps D,Raczynski J,Somers VK,Jaffe AS

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:A subset of patients hospitalized with acute heart failure experiences in-hospital worsening heart failure, defined as persistent or worsening signs or symptoms requiring an escalation of therapy. METHODS:We analyzed data from the Acute Decompensated Heart Failure National Registry (ADHERE) linked to Medica...

journal_title：American heart journal

authors： DeVore AD,Greiner MA,Sharma PP,Qualls LG,Schulte PJ,Cooper LB,Mentz RJ,Pang PS,Fonarow GC,Curtis LH,Hernandez AF

更新日期：2016-08-01 00:00:00

abstract：:Chronic maintenance tocainide therapy was effective in controlling symptomatic, recurrent ventricular tachycardia in 11 of 15 patients. Patients were selected for tocainide therapy on the basis of refractoriness to conventional antiarrhythmic agents and responsiveness to the intravenous administration of lidocaine. Si...

journal_title：American heart journal

authors： Maloney JD,Nissen RG,McColgan JM

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:Diastolic dysfunction is common immediately after coronary artery bypass surgery (CABG). The duration of this phenomenon is unknown. Intravenous calcium is frequently administered during separation from cardiopulmonary bypass (CPB). We sought to determine whether intravenous calcium influences perioperative ...

journal_title：American heart journal

authors： Ekery DL,Davidoff R,Orlandi QG,Apstein CS,Hesselvik JF,Shemin RJ,Shapira OM

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Previous research suggests that after coronary artery bypass graft (CABG) surgery, women fare worse than men. This study investigates sex differences in depression during recovery from CABG surgery. METHODS:We followed 137 patients (72 men, 65 women) undergoing elective isolated first CABG surgery between J...

journal_title：American heart journal

authors： Mitchell RH,Robertson E,Harvey PJ,Nolan R,Rodin G,Romans S,Abramson BL,Brister SJ,Ivanov J,Stewart DE

更新日期：2005-11-01 00:00:00

abstract：:Limited data are available on mitral valve replacement in the elderly patient. Therefore we report our 10-year experience including predictors of perioperative mortality and subsequent long-term cardiac mortality in elderly patients with mitral valve replacement compared to younger patients. Of the 126 consecutive pat...

journal_title：American heart journal

authors： Nair CK,Biddle WP,Kaneshige A,Cook C,Ryschon K,Sketch MH Sr

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Concerns raised regarding adverse cardiovascular (CV) outcomes with new therapies for type 2 diabetes mellitus (T2DM) have led to several large-scale CV outcome trials. The EXAMINE trial confirmed noninferiority of the dipeptidyl dipeptidase 4 inhibitor alogliptin to placebo on major adverse cardiac event ra...

journal_title：American heart journal

authors： Shimada YJ,Cannon CP,Liu Y,Wilson C,Kupfer S,Menon V,Cushman WC,Mehta CR,Bakris GL,Zannad F,White WB,EXAMINE Investigators.

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Despite a survival benefit and guideline recommendation for beta-blockers in left ventricular systolic dysfunction, beta-blockers are underused in clinical practice. METHODS:Medical practices with > or = 15 patients with heart failure (HF) in the Duke Databank for Cardiovascular Disease (DDCD) were identifi...

journal_title：American heart journal

authors： LaPointe NM,DeLong ER,Chen A,Hammill BG,Muhlbaier LH,Califf RM,Kramer JM

更新日期：2006-05-01 00:00:00

abstract：:The purpose of this study was to determine the effect of age on the in-hospital mortality of all 30,972 patients undergoing coronary artery bypass graft (CABG) surgery in New York in 1991 and 1992. Mortality rates were relatively low for patients 40-49, 50-59, and 60-64, 65-69, and 70-74 years old (1.10%, 1.65%, 2.17%...

journal_title：American heart journal

authors： Hannan EL,Burke J

更新日期：1994-12-01 00:00:00

abstract：:The records of 64 patients with progressive systemic sclerosis (PSS) were reviewed. More than 100 items from the patient's history, physical examination, and laboratory tests were encoded. A two-tailed Gehan's test was used to evaluate the effect of each variable on patient survival. Variables significant at the 0.05 ...

journal_title：American heart journal

authors： Wynn J,Fineberg N,Matzer L,Cortada X,Armstrong W,Dillon JC,Kinney EL

更新日期：1985-07-01 00:00:00

abstract：:Continuous-mode Doppler ultrasound and cardiac catheterization were performed within 1.4 +/- 2.0 days in 70 patients, aged 26 to 84 (mean 67 +/- 11) years, with suspected aortic stenosis. Optimal Doppler spectral display signal was recorded from the apical window in 43% of the patients, the second or third right paras...

journal_title：American heart journal

authors： Panidis IP,Mintz GS,Ross J

更新日期：1986-07-01 00:00:00

abstract：:Adenosine thallium stress testing has a demonstrated utility in the detection of coronary artery disease. The optimal dose for diagnostic efficacy with minimal side effects has not been critically evaluated. A randomized 3- and 6-minute infusion of adenosine (140 micrograms/kg/min) was performed in 11 subjects. Subjec...

journal_title：American heart journal

authors： Villegas BJ,Hendel RC,Dahlberg ST,McSherry BA,Leppo JA

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Contemporary use of dual antiplatelet therapy and consistency with guideline recommendations in acute coronary syndrome patients undergoing percutaneous coronary intervention (PCI) have not been well characterized. METHODS:The COAPT was a prospective, observational, multicenter, longitudinal study of patien...

journal_title：American heart journal

authors： Déry JP,Mehta SR,Fisher HN,Zhang X,Zhu YE,Welsh RC,Lavi S,Cieza T,Henderson MA,Lutchmedial S,Siega AJ,Cheema AN,Wong BY,Kokis A,Dehghani P,Goodman SG,Canadian Observational AntiPlatelet sTudy (COAPT) Investigators.

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:This study examines how the dissemination of stenting and procedural shifts to high-volume facilities have affected short-term outcomes after percutaneous coronary intervention (PCI). METHODS:Discharge information from the 1994 and 1997 US Nationwide Inpatient Sample was used. Data from 1994 involved 84,036...

journal_title：American heart journal

authors： Watanabe CT,Maynard C,Ritchie JL

更新日期：2002-08-01 00:00:00

abstract：:To elucidate the long-term outcome and frequency of complications after heart transplantation for peripartum cardiomyopathy (PPCM), we compared the courses of eight consecutive patients undergoing transplantation for PPCM with those of nine female age-matched control subjects undergoing transplantation for idiopathic ...

journal_title：American heart journal

authors： Rickenbacher PR,Rizeq MN,Hunt SA,Billingham ME,Fowler MB

更新日期：1994-05-01 00:00:00