Use of aspirin for prevention of cardiovascular disease--1981-82 to 1985-86: the Minnesota Heart Survey.

Abstract:

:The efficacy of aspirin to prevent ischemic cardiovascular disease has received considerable attention recently. To determine the prevalence of aspirin use for cardiovascular disease prevention, the Minnesota Heart Survey examined population-based samples of Twin Cities' adults in 1981 to 82 and 1985 to 86. Over the 4-year period, reported use of aspirin for cardiovascular disease prophylaxis increased from 0.6% to 2.4% in women (p less than 0.05) and from 1.7% to 3.3% in men (p = 0.10). Prophylactic aspirin use was more common in older than in younger adults, in whites than in blacks, in those with a history of cardiovascular disease or hypercholesterolemia, and in health professionals and nonsmokers. Some individuals were apparently taking aspirin for "primary" prevention, although it has not yet been approved for that reason. Use of aspirin for cardiovascular disease prevention has been increasing and is likely to increase more rapidly over the next few years. This could favorably impact on mortality rates of cardiovascular disease, but untoward side effects of aspirin may be expected to increase as well.

journal_name

Am Heart J

journal_title

American heart journal

authors

Folsom AR,Iso H,Sprafka JM,Edlavitch SA,Luepker RV

doi

10.1016/0002-8703(88)90344-4

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

827-30

issue

3

eissn

0002-8703

issn

1097-6744

pii

0002-8703(88)90344-4

journal_volume

116

pub_type

杂志文章
  • Adverse reactions to methyldopa with particular reference to hypotension.

    abstract::Of 26,294 consecutive patients monitored in a comprehensive drug surveillance program, 1067 (4 per cent) received methyldopa for treatment of hypertension. Adverse reactions attributed to methyldopa were reported in 149 patients (14 per cent), the most frequent being hypotension. Life-threatening adverse effects were ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(78)90192-8

    authors: Lawson DH,Gloss D,Jick H

    更新日期:1978-11-01 00:00:00

  • Two forms of hypertrophic cardiomyopathy distinguished by inheritance of HLA haplotypes and left ventricular outflow tract obstruction.

    abstract::In this study we have performed human leukocyte antigen (HLA)-A and B typing on nine patients with hypertrophic cardiomyopathy (HCM) and their relatives. Four patients had relatives who also had the disease. HLA typing of the familial form of HCM revealed a very close association of a given HLA-A,B haplotype with the ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(83)90401-5

    authors: Kishimoto C,Kaburagi T,Takayama S,Yokoyama S,Hanyu I,Takatsu Y,Tomimoto K

    更新日期:1983-06-01 00:00:00

  • Pathology of sinoatrial node. Correlations with electrocardiographic findings in 111 patients.

    abstract::Histological study of the sinoatrial node (SAN) was performed in 111 patients in order to estabilsh correlations between the ECG findings and the anatomical lesions. This series includes both patients with sinus rhythm and patients with atrial arrhythmias. The results are as fololows: (a) the amount of nodal cells in ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(77)80070-7

    authors: Thery C,Gosselin B,Lekieffre J,Warembourg H

    更新日期:1977-06-01 00:00:00

  • Efficacy of prolonged infusion of urodilatin [ANP-(95-126)] in patients with congestive heart failure.

    abstract::Urodilatin [ANP-95-126] is a new natriuretic peptide of renal origin not subjected to tolerance in experimental congestive heart failure (CHF). To evaluate its therapeutic potentials in CHF, we investigated the efficacy of a prolonged infusion of urodilatin (15 ng/kg/min for 10 hours) in 12 patients with CHF (New York...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-8703(95)90328-3

    authors: Elsner D,Muders F,Müntze A,Kromer EP,Forssmann WG,Riegger GA

    更新日期:1995-04-01 00:00:00

  • Renin-angiotensin system: genes to bedside.

    abstract::Atherosclerosis and its vascular sequela are responsible for considerable morbidity and mortality rates. Several risk factors have been implicated in the pathogenesis of atherosclerosis, and the search for other risk factors continues on the medical horizon. Renin-angiotensin system (RAS), a multienzyme, multilocale a...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/s0002-8703(97)70089-9

    authors: Malik FS,Lavie CJ,Mehra MR,Milani RV,Re RN

    更新日期:1997-09-01 00:00:00

  • The rationale and design of the FORomegaARD Trial: A randomized, double-blind, placebo-controlled, independent study to test the efficacy of n-3 PUFA for the maintenance of normal sinus rhythm in patients with previous atrial fibrillation.

    abstract:BACKGROUND:Atrial fibrillation (AF) is associated with increased risk of death, thromboembolic complications, and a lowered quality of life. Despite this burden, pharmacologic agents for prevention of AF in patients who achieved normal sinus rhythm are of limited utility, mostly because of serious and frequent side eff...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2008.10.027

    authors: Macchia A,Varini S,Grancelli H,Nul D,Laffaye N,Ferrante D,Tognoni G,Doval HC,FORomegaARD investigators.

    更新日期:2009-03-01 00:00:00

  • Insulin sensitivity in young women with vasovagal syncope.

    abstract:BACKGROUND:Insulin, in addition to its known metabolic effects, has sympatho-excitatory and vasodilatory actions on muscular blood vessels. The goal of this study was to evaluate insulin sensitivity in young women with vasovagal syncope and positive tilt test results (HUT+) and to compare it with that in patients with ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/S0002-8703(02)94707-1

    authors: Ruiz GA,Calvar C,Hermes R,Rivadeneira D,Bengolea V,Chirife R,Tentori MC,Gelpi RJ

    更新日期:2003-05-01 00:00:00

  • Hemodynamic effects of alinidine (ST 567) at rest and during exercise in patients with chronic congestive heart failure.

    abstract::Selective inhibition of sinus node function offers the possibility to decrease heart rate and reduce myocardial oxygen consumption in patients with impaired cardiac function, if myocardial contractility is not further attenuated. To study the influence of a specific sinus node inhibitor on myocardial function, alinidi...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(05)80185-1

    authors: Koenig W,Stauch M,Sund M,Wanjura D,Henze E

    更新日期:1990-06-01 00:00:00

  • Effect of viscosity and iodine concentration of nonionic radiographic contrast media on coronary arteriography in patients.

    abstract::To assess the influence of viscosity and iodine concentration, three matched and standardized left coronary arteriograms were obtained in 20 patients using iopamidol (Isovue-370), ioversol (Optiray-320), and iohexol (Omnipaque-350). The order of contrast media was randomized and the administration of contrast was doub...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0002-8703(92)90760-s

    authors: Kern MJ,Roth RA,Aguirre FV,Beauman G,Vogel R

    更新日期:1992-01-01 00:00:00

  • Effect of the G-308A polymorphism of the tumor necrosis factor alpha gene on the risk of ischemic heart disease and ischemic stroke: a meta-analysis.

    abstract:BACKGROUND:Under the hypothesis that the G-308A polymorphism in the promoter region of the tumor necrosis factor alpha gene might increase tumor necrosis factor alpha expression, several investigations have been performed to examine the influence of the -308A allele on the risk of cardiovascular events. The results of ...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ahj.2007.02.031

    authors: Pereira TV,Rudnicki M,Franco RF,Pereira AC,Krieger JE

    更新日期:2007-05-01 00:00:00

  • Myocardial infarct size reduction by the synergistic effect of hyperbaric oxygen and recombinant tissue plasminogen activator.

    abstract::Fasting mongrel dogs underwent hyperbaric oxygen treatment (HBOT), recombinant tissue plasminogen activator (rt-PA) treatment, and simultaneous HBOT and rt-PA treatment following prior experimental left anterior descending coronary artery occlusion for 2 hours. Thrombosis in and around a copper coil was recorded angio...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(90)90194-3

    authors: Thomas MP,Brown LA,Sponseller DR,Williamson SE,Diaz JA,Guyton DP

    更新日期:1990-10-01 00:00:00

  • The evolving costs of intracoronary stents.

    abstract:BACKGROUND:As stenting practice has evolved to include greater numbers of stents and adjunctive balloon catheters per case, concern has focused on the increasing costs of equipment for the delivery of stents. METHODS AND RESULTS:To evaluate temporal changes in costs of intracoronary stenting, we examined total costs, ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(98)70193-0

    authors: Vaitkus PT,Adele C,Wells SK,Zehnacker JP

    更新日期:1998-07-01 00:00:00

  • Design and rationale for the Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction 54 (PEGASUS-TIMI 54) trial.

    abstract:BACKGROUND:P2Y12 receptor antagonist therapy is recommended in addition to ASA for up to 1 year after acute coronary syndrome to reduce ischemic events. In contrast, the benefit of long-term dual antiplatelet therapy beyond 1 year remains unclear. Ticagrelor is a potent, reversibly binding P2Y12 receptor-antagonist tha...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/j.ahj.2013.12.020

    authors: Bonaca MP,Bhatt DL,Braunwald E,Cohen M,Steg PG,Storey RF,Held P,Jensen EC,Sabatine MS

    更新日期:2014-04-01 00:00:00

  • Identification of the ischemic etiology of heart failure by cardiovascular magnetic resonance imaging: diagnostic accuracy of late gadolinium enhancement.

    abstract:BACKGROUND:A large proportion of patients with heart failure (HF) have a large and poorly contracting left ventricle. The noninvasive recognition of the ischemic etiology of such patients is difficult, and for this purpose, usually patients undergo coronary angiography. It has been shown that cardiovascular magnetic re...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2005.03.068

    authors: Casolo G,Minneci S,Manta R,Sulla A,Del Meglio J,Rega L,Gensini G

    更新日期:2006-01-01 00:00:00

  • Transpulmonary passage of Albunex as a marker of intracardiac hemodynamics and outcome in chronic congestive heart failure.

    abstract:BACKGROUND:Aggressive management to reduce pulmonary artery systolic pressure (PASP) and pulmonary capillary wedge pressure (PCWP) reduces hospitalization rates and is crucial for patients awaiting transplantation but may require periodic invasive monitoring with right heart catheterization. METHODS:The purpose of thi...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(00)90008-5

    authors: Sherman HL,Avelar E,Grossman PM,Sachdev V,Oral H,Nicklas JM,Armstrong WF

    更新日期:2000-05-01 00:00:00

  • Preoperative angiotensin-blocking drug therapy is not associated with atrial fibrillation after cardiac surgery.

    abstract:BACKGROUND:Preoperative use of angiotensin-blocking drug therapy (ABDT) with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and its link to occurrence of postoperative atrial fibrillation (POAF), a common marker of poor outcomes after cardiac surgery, remain controversial. METHODS:From 19...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2010.05.033

    authors: Rader F,Van Wagoner DR,Gillinov AM,Blackstone EH

    更新日期:2010-08-01 00:00:00

  • Protective effect of the CYP2C19 *17 polymorphism with increased activation of clopidogrel on cardiovascular events.

    abstract:BACKGROUND:The prodrug clopidogrel requires activation by cytochrome P-450 (CYP) enzymes for its antiplatelet effect. The genes encoding enzymes for clopidogrel activation are polymorphic, leading to reduced or increased function, depending on the respective genotype. Reduced-function alleles have been associated with ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2010.06.039

    authors: Tiroch KA,Sibbing D,Koch W,Roosen-Runge T,Mehilli J,Schömig A,Kastrati A

    更新日期:2010-09-01 00:00:00

  • Left atrial function assessed by real-time 3-dimensional echocardiography is related to right ventricular systolic pressure in chronic mitral regurgitation.

    abstract:BACKGROUND:Left atrial (LA) volume is a prognostic index in chronic mitral regurgitation (MR). However, little is known about LA function in this setting. We hypothesized that LA dysfunction is related to pulmonary hypertension in chronic MR. METHODS:Seventy-one patients with organic chronic MR who underwent real-time...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2009.05.030

    authors: Saraiva RM,Yamano T,Matsumura Y,Takasaki K,Toyono M,Agler DA,Greenberg N,Thomas JD,Shiota T

    更新日期:2009-08-01 00:00:00

  • Effects of warfarin on markers of hypercoagulability in patients with heart failure.

    abstract::Heart failure is associated with a hypercoagulable state. A single-center, randomized, double-blind, placebo-controlled trial was performed to test the hypothesis that warfarin will modify a hypercoagulable state in heart failure. This study included 76 patients with heart failure. At baseline, patients had evidence f...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-8703(97)70103-0

    authors: Jafri SM,Mammen EF,Masura J,Goldstein S

    更新日期:1997-07-01 00:00:00

  • Can computerization of the exercise test replace the cardiologist?

    abstract:BACKGROUND:The type of practitioners who use the standard exercise test is changing. Once a tool of the cardiologist, the standard exercise test is now being performed by internists and other noncardiologists. Because this change could be facilitated by computerization similar to the computerized interpretation program...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s0002-8703(98)70233-9

    authors: Atwood JE,Do D,Froelicher V,Chilton R,Dennis C,Froning J,Janosi A,Mortara D,Myers J

    更新日期:1998-09-01 00:00:00

  • Validation of pressure-volume data obtained in patients by initial transit radionuclide angiocardiography.

    abstract::In order to validate the measurement of pressure-volume loops and stroke work in humans, simultaneous digital subtraction ventriculography (DSA) and first-pass radionuclide angiocardiography (RNA) coupled with high-fidelity micromanometer left ventricular pressure measurements were undertaken in 34 patients, mean age ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(89)90234-2

    authors: Harpole DH,Skelton TN,Davidson CJ,Jones RH,Bashore TM

    更新日期:1989-11-01 00:00:00

  • Angiographic correlates of recurrent sustained ventricular tachycardia in chronic ischemic heart disease.

    abstract::We report the angiographic studies of 53 consecutive patients with angiographic coronary artery disease (CAD) and recurrent sustained ventricular tachycardia occurring at least 6 weeks remote from an acute myocardial infarction. Triple-vessel disease was present in 25 patients (47%), double-vessel disease in 19 patien...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(83)90392-7

    authors: Lam W,Pietras R,Bauernfeind R,Swiryn S,Strasberg B,Palileo E,Rosen KM

    更新日期:1983-06-01 00:00:00

  • Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes.

    abstract:BACKGROUND:Coronary artery disease (CAD) and, increasingly, diabetes are recognized as having an inflammatory basis. Membrane toll-like receptors (TLRs) activate signaling pathways that up-regulate inflammation. We evaluated whether the Asp299Gly polymorphism in the TLR4 gene, which impairs inflammatory responses, is a...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2004.05.049

    authors: Kolek MJ,Carlquist JF,Muhlestein JB,Whiting BM,Horne BD,Bair TL,Anderson JL

    更新日期:2004-12-01 00:00:00

  • Coronary artery calcification, atherogenic lipid changes, and increased erythrocyte volume in black injection drug users infected with human immunodeficiency virus-1 treated with protease inhibitors.

    abstract:BACKGROUND:Protease inhibitors (PIs) may be associated with accelerated atherosclerosis in individuals infected with human immunodeficiency virus (HIV). We assessed the effects of HIV PIs on subclinical atherosclerosis. METHODS:The lipid profiles, C-reactive protein (CRP) levels, coronary artery calcification (CAC) sc...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2002.125009

    authors: Meng Q,Lima JA,Lai H,Vlahov D,Celentano DD,Strathdee SA,Nelson KE,Wu KC,Chen S,Tong W,Lai S

    更新日期:2002-10-01 00:00:00

  • Angiotensin inhibition in renovascular disease: a population-based cohort study.

    abstract:BACKGROUND:Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers effectively reduce blood pressure in patients with renovascular disease (RVD); yet, randomized cardiovascular prevention trials of these drugs typically exclude individuals with this condition. PATIENTS AND METHODS:We studied the ass...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2008.05.013

    authors: Hackam DG,Duong-Hua ML,Mamdani M,Li P,Tobe SW,Spence JD,Garg AX

    更新日期:2008-09-01 00:00:00

  • Evaluation of cardiac function of the fetus by inferior vena cava diameter pulse waveform.

    abstract:BACKGROUND:The diameter pulse waveforms (DPWs) are known to reflect the pressure waveforms at the target vessel. Our purpose was to clarify the usefulness of DPWs recorded noninvasively from the fetal inferior vena cava (IVC) for detecting cardiac function. METHODS:A paired ultrasonic phase-locked echo tracking system...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2007.06.015

    authors: Mori A,Uchida N,Ishiguro Y,Atsuko T,Kanako M,Mikio M

    更新日期:2007-10-01 00:00:00

  • Prevalence of congenital heart disease.

    abstract:BACKGROUND:Today most patients with congenital heart disease survive childhood to be cared for by adult cardiologists. The number of physicians that should be trained to manage these lesions is unknown because we do not know the number of patients. METHODS:To answer this question, the expected numbers of infants with ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2003.05.003

    authors: Hoffman JI,Kaplan S,Liberthson RR

    更新日期:2004-03-01 00:00:00

  • Coronary microvascular dysfunction is highly prevalent in women with chest pain in the absence of coronary artery disease: results from the NHLBI WISE study.

    abstract:BACKGROUND:Chest pain in the absence of obstructive coronary artery disease (CAD) is common in women; it is frequently associated with debilitating symptoms and repeated evaluations and may be caused by coronary microvascular dysfunction. However, the prevalence and determinants of microvascular dysfunction in these wo...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2001.114198

    authors: Reis SE,Holubkov R,Conrad Smith AJ,Kelsey SF,Sharaf BL,Reichek N,Rogers WJ,Merz CN,Sopko G,Pepine CJ,WISE Investigators.

    更新日期:2001-05-01 00:00:00

  • Acute coronary occlusion following blunt injury to the chest in the absence of coronary atherosclerosis.

    abstract::A 35-year-old man suffered transmural diaphragmatic wall infarction immediately after receiving a nonpenetrating trauma to his chest. During subsequent months crippling angina pectoris developed and coronary arteriography was performed. A complete obstruction of the left circumflex coronary artery was demonstrated 2 c...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(76)80051-8

    authors: Oren A,Bar-Shlomo B,Stern S

    更新日期:1976-10-01 00:00:00

  • Comparison of transradial and femoral approaches for percutaneous coronary interventions: a systematic review and hierarchical Bayesian meta-analysis.

    abstract:BACKGROUND:Despite lower risks of access site-related complications with transradial approach (TRA), its clinical benefit for percutaneous coronary intervention (PCI) is uncertain. We conducted a systematic review and meta-analysis of clinical studies comparing TRA and transfemoral approach (TFA) for PCI. METHODS:Rand...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ahj.2012.01.015

    authors: Bertrand OF,Bélisle P,Joyal D,Costerousse O,Rao SV,Jolly SS,Meerkin D,Joseph L

    更新日期:2012-04-01 00:00:00