Optimal features of a new beta-blocker.

abstract：BACKGROUND:We sought to systematically evaluate whether percutaneous revascularization is associated with additional clinical benefit in patients with renal artery stenosis (RAS) as compared with medical management alone. METHODS:We included randomized controlled trials that compared percutaneous revascularization in ...

journal_title：American heart journal

authors： Kumbhani DJ,Bavry AA,Harvey JE,de Souza R,Scarpioni R,Bhatt DL,Kapadia SR

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The aim of this study was to compare rate of onset, magnitude, and consistency of platelet inhibition after administration of prasugrel or clopidogrel and to relate platelet inhibition to systemic exposure to each active metabolite. Thienopyridines are prodrugs, metabolized in vivo to active metabolites that...

journal_title：American heart journal

authors： Brandt JT,Payne CD,Wiviott SD,Weerakkody G,Farid NA,Small DS,Jakubowski JA,Naganuma H,Winters KJ

更新日期：2007-01-01 00:00:00

abstract：:Interatrial septal aneurysm (IASA) has been detected with increasing frequency since the advent of two-dimensional echocardiography (2DE). In this study, we investigated the prevalence, characteristics, and predisposing factors in IASA formation in 724 infants, children, and adolescents undergoing 2DE. Among this grou...

journal_title：American heart journal

authors： Wolf WJ,Casta A,Sapire DW

更新日期：1987-05-01 00:00:00

abstract：:The records of 64 patients with progressive systemic sclerosis (PSS) were reviewed. More than 100 items from the patient's history, physical examination, and laboratory tests were encoded. A two-tailed Gehan's test was used to evaluate the effect of each variable on patient survival. Variables significant at the 0.05 ...

journal_title：American heart journal

authors： Wynn J,Fineberg N,Matzer L,Cortada X,Armstrong W,Dillon JC,Kinney EL

更新日期：1985-07-01 00:00:00

abstract：:To assess the effects of pacing-induced tachycardia on phasic coronary blood flow pattern and flow reserve of left anterior descending artery, we examined 16 patients with chest pain and angiographically normal coronary arteries by using an intravascular Doppler catheter with spectral analysis of the velocity signal. ...

journal_title：American heart journal

authors： Hongo M,Nakatsuka T,Watanabe N,Takenaka H,Tanaka M,Kinoshita O,Okubo S,Sekiguchi M

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:P2Y12 receptor antagonist therapy is recommended in addition to ASA for up to 1 year after acute coronary syndrome to reduce ischemic events. In contrast, the benefit of long-term dual antiplatelet therapy beyond 1 year remains unclear. Ticagrelor is a potent, reversibly binding P2Y12 receptor-antagonist tha...

journal_title：American heart journal

authors： Bonaca MP,Bhatt DL,Braunwald E,Cohen M,Steg PG,Storey RF,Held P,Jensen EC,Sabatine MS

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) improves symptoms, reduces heart failure (HF)-related hospitalizations, and reverses left ventricular remodeling in some patients with moderate to severe HF and ventricular dyssynchrony defined by a prolonged QRS duration. The effects of CRT on HF outcomes in patients ...

journal_title：American heart journal

authors： Linde C,Gold M,Abraham WT,Daubert JC,REVERSE Study Group.

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Sirolimus-eluting stents (SES) prevent restenosis and repeat percutaneous coronary intervention (PCI), but safety data in unselected patients are limited, especially for intermediate-term follow-up. METHODS:All patients undergoing SES implantation at 4 Italian centers were enrolled into a dedicated database...

journal_title：American heart journal

authors： Sangiorgi G,Romagnoli E,Biondi-Zoccai G,Margheri M,Tamburino C,Barbagallo R,Falchetti E,Vittori G,Agostoni P,Cosgrave J,Colombo A,RECIPE (Real-world Eluting-stent Comparative Italian retrosPective Evaluation) Study Investigators.

更新日期：2008-11-01 00:00:00

abstract：:Resting measurements of left ventricular systolic function do not reliably predict exercise capacity in patients with cardiac disease. Therefore left ventricular filling shortly after a myocardial infarction was prospectively studied to determine whether it could predict subsequent exercise time. Consecutive patients ...

journal_title：American heart journal

authors： Finkelhor RS,Sun JP,Bahler RC

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) ablation is superior to pharmacologic therapy in achieving maintenance of normal sinus rhythm in selected patient populations. However, the procedure is resource intensive, and repeat ablations are sometimes required. We examined the predictors and trends of repeat ablation using a l...

journal_title：American heart journal

authors： Al-Hijji MA,Deshmukh AJ,Yao X,Mwangi R,Sangaralingham LR,Friedman PA,Asirvatham SJ,Packer DL,Shah ND,Noseworthy PA

更新日期：2016-01-01 00:00:00

abstract：:Inducible ventricular tachycardia frequently persists despite solitary class I antiarrhythmic drug therapy. To determine the effect of metoprolol as adjuvant therapy, 19 patients with clinical ventricular tachycardia with baseline inducible sustained monomorphic ventricular tachycardia and persistently inducible ventr...

journal_title：American heart journal

authors： Brodsky MA,Chough SP,Allen BJ,Capparelli EV,Orlov MV,Caudillo G

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Data derived from stress myocardial perfusion imaging (MPI) carry prognostic significance in young patients with hypertrophic cardiomyopathy (HCM), but there are limited data on the utility of stress MPI in patients with HCM who are older. This study examined the prognostic significance of stress MPI in an a...

journal_title：American heart journal

authors： Sorajja P,Chareonthaitawee P,Ommen SR,Miller TD,Hodge DO,Gibbons RJ

更新日期：2006-02-01 00:00:00

abstract：:Inhibition of the enzyme that synthesizes thromboxanes may protect against the development of ventricular fibrillation (VF) during acute myocardial ischemia. This study was carried out to test this hypothesis with a new thromboxane synthetase inhibitor, and to extend the studies to alternative animal models of myocard...

journal_title：American heart journal

authors： O'Connor KM,Friehling TD,Kowey PR

更新日期：1989-04-01 00:00:00

abstract：:The present study refers to six patients in whom an A-V reciprocal rhythm could be documented; in four cases it took the form of sustained tachycardia. None of the patients showed any ECG feature of ventricular pre-excitation (PR interval of more than 0.12 sec. and normal QRS configuration). The extrastimulus method s...

journal_title：American heart journal

authors： Touboul P,Huerta F,Porte J,Delahaye JP

更新日期：1976-01-01 00:00:00

abstract：:The P and the Ta waves of two patient groups with A-V block were magnified with a direct-current amplifier and recorded at a high paper speed. In Group A patients (those without serious cardiovascular complications except A-V block) the P and the Ta waves were recorded in the opposite direction in every lead and there...

journal_title：American heart journal

authors： Hayashi H,Okajima M,Yamada K

更新日期：1976-06-01 00:00:00

abstract：:The acute hemodynamic and hormonal effects of the oral angiotensin-converting enzyme (ACE) inhibitor lisinopril (MK-521) were assessed over a period of 96 hours in 12 patients with heart failure. This compound is the lysine analogue of enalaprilat (MK-422), is biologically active following absorption, and is cleared v...

journal_title：American heart journal

authors： Dickstein K,Aarsland T,Woie L,Abrahamsen AM,Fyhrquist F,Cummings S,Gomex HJ,Hagen E,Kristianson K

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:The long-term fate of patent irradiated segments at 6 months after beta-radiation therapy has not been sufficiently evaluated. METHODS:Two-year follow-up angiography was performed in 52 patients with patent irradiated segments at 6 months after beta-radiation with a rhenium 188-mercaptoacetyltriglycine-fill...

journal_title：American heart journal

authors： Lee SW,Park SW,Hong MK,Kim YH,Han KH,Kim J,Park JH,Oh SJ,Moon DH,Oh SJ,Lee CW,Kim JJ,Park SJ

更新日期：2006-01-01 00:00:00

abstract：:sulfoconjugated dopamine constitutes the major portion of circulating or excreted dopamine, but its physiologic significance is still unknown. To test whether conjugated dopamine serves as a source of free dopamine in response to acute stress, plasma concentrations of free and conjugated dopamine were measured during ...

journal_title：American heart journal

authors： Nakaya Y,Katayama T,Nomura M,Ishimura Y,Ohuchi T,Oka M,Yamamoto M,Mizobuchi S

更新日期：1994-03-01 00:00:00

abstract：:Cardiac pacing initiated from epicardial or transvenous apical right ventricular electrodes causes asynchronous ventricular contraction. This alters myocardial stress vectors and results in adverse cellular and subcellular changes in the experimental animal. Clinically, such changes may contribute to the adverse hemod...

journal_title：American heart journal

authors： Karpawich PP,Justice CD,Chang CH,Gause CY,Kuhns LR

更新日期：1991-03-01 00:00:00

abstract：:The manner in which concealed anterograde impulse penetration may affect retrograde atrioventricular nodal conduction was studied systematically in 12 patients with intact ventriculoatrial (VA) conduction. After the last beat of a basic atrial drive (A1), an extrastimulus (A2) was introduced 20 msec inside the effecti...

journal_title：American heart journal

authors： Lehmann MH,Mahmud R,Denker ST,Tchou PJ,Dongas J,Akhtar M

更新日期：1987-12-01 00:00:00

abstract：:Transient U wave inversion can be caused either by regional myocardial ischemia or by an elevation of systemic blood pressure. The characteristics of U wave inversion during chest pain attacks in 21 patients with variant angina were compared with those observed in 38 patients with hypertension without apparent ischemi...

journal_title：American heart journal

authors： Miwa K,Miyagi Y,Fujita M,Fujiki A,Sasayama S

更新日期：1993-04-01 00:00:00

abstract：:The main threat to patients with mild to moderate hypertension is coronary heart disease (CHD), but controlled trials of antihypertensive drug therapy have given disappointing results: overall, the reduction in CHD mortality (11%) and morbidity (10%) were small and nonsignificant. Recent trials comparing a beta blocke...

journal_title：American heart journal

authors： Rose G

更新日期：1987-10-01 00:00:00

abstract：:The hemodynamic, electrocardiographic, and metabolic responses of dogs with acute myocardial ischemia to intravenous administration of fructose-1,6-diphosphate (FDP) were assessed. Analysis of the results (compared to dextrose control) revealed evidence of major improvement of LVEDP and cardiac output, significant dec...

journal_title：American heart journal

authors： Markov AK,Oglethorpe NC,Blake TM,Lehan PH,Hellems HK

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:The latest cholesterol guidelines have shifted focus from achieving low-density lipoprotein cholesterol (LDL-C) targets toward statin use and intensity guided by atherosclerotic cardiovascular disease (ASCVD) risk. METHODS:Statin use and intensity were evaluated in 5,905 statin-eligible primary or secondary...

journal_title：American heart journal

authors： Navar AM,Wang TY,Li S,Robinson JG,Goldberg AC,Virani S,Roger VL,Wilson PWF,Elassal J,Lee LV,Peterson ED

更新日期：2017-11-01 00:00:00

abstract：:The relationship between coronary artery size and left ventricular (LV) muscle mass was studied in 10 control subjects and in 10 patients with chronic mitral regurgitation before and 28 +/- 15 months after mitral valve surgery. Left and right coronary artery size was determined by quantitative coronary arteriography. ...

journal_title：American heart journal

authors： Vassalli G,Hess OM,Krogmann ON,Villari B,Corin WJ,Turina M,Krayenbuehl HP

更新日期：1993-11-01 00:00:00

abstract：:Postoperative atrial fibrillation/flutter (PoAF) commonly complicates cardiac surgery, occurring in 25% to 60% of patients. Postoperative atrial fibrillation/flutter is associated with significant morbidity, higher long-term mortality, and increased health care costs. Novel preventive therapies are clearly needed. In ...

journal_title：American heart journal

authors： Mozaffarian D,Marchioli R,Gardner T,Ferrazzi P,O'Gara P,Latini R,Libby P,Lombardi F,Macchia A,Page R,Santini M,Tavazzi L,Tognoni G

更新日期：2011-07-01 00:00:00

abstract：:Recent developments have provided a unique opportunity for the organization of regional ST-elevation myocardial infarction (STEMI) receiving center (SRC) networks. Because cumulative evidence has demonstrated that rapid primary percutaneous coronary intervention (PCI) is the most effective reperfusion strategy for acu...

journal_title：American heart journal

authors： Rokos IC,Larson DM,Henry TD,Koenig WJ,Eckstein M,French WJ,Granger CB,Roe MT

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The nested case-control study is an efficient epidemiological design whereby a case-control approach is employed within an established cohort. The large number of recent prospective studies and randomized trials conducted in cardiology provide cohorts within which the nested case-control approach is increasi...

journal_title：American heart journal

authors： Essebag V,Genest J Jr,Suissa S,Pilote L

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Peculiar asynergy, which consists of hypokinesis or akinesis from the mid portion to the apical area and hyperkinesis of the basal area on contrast left ventriculogram, is rare. Because the end-systolic left ventriculogram looks like a "tako-tsubo," which was used for trapping octopuses in Japan, we proposed...

journal_title：American heart journal

authors： Kurisu S,Sato H,Kawagoe T,Ishihara M,Shimatani Y,Nishioka K,Kono Y,Umemura T,Nakamura S

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Erythropoietin mitigates myocardial damage and improves ventricular performance after experimental ischemic injury. This study assessed safety and efficacy markers relevant to the biological activity of recombinant human erythropoietin (rHuEpo) in patients with acute myocardial infarction (MI). METHODS:We c...

journal_title：American heart journal

authors： Tang YD,Hasan F,Giordano FJ,Pfau S,Rinder HM,Katz SD

更新日期：2009-12-01 00:00:00