Abstract:
:To elucidate the long-term outcome and frequency of complications after heart transplantation for peripartum cardiomyopathy (PPCM), we compared the courses of eight consecutive patients undergoing transplantation for PPCM with those of nine female age-matched control subjects undergoing transplantation for idiopathic dilated cardiomyopathy (IDCM). No significant differences could be found in baseline variables between the two groups with the exception of the number of pregnancies (2.5 +/- 1.5 vs 0, p = 0.0002). Two patients in each group died during the first 6 months after transplantation, and one in each group died later. Actuarial survival rates were 75% +/- 15% and 78% +/- 14% (p = NS) at 1 year and 60% +/- 18% and 78% +/- 14% (p = NS) at 5 years in PPCM and IDCM patients, respectively. Linearized rejection rates during the first 3 months were 1.85 +/- 0.56 and 1.91 +/- 0.49 (p = NS) and during the second 3 months were 0.18 +/- 0.18 and 0.45 +/- 0.26 (p = NS), respectively. Similarly no significant differences in linearized infection rates were found. Among patients surviving more than 6 months after transplantation, after a mean follow-up period of 4.5 +/- 3.1 years for those with PPCM and 7.8 +/- 3.2 years for those with IDCM, 83% and 100%, respectively, were rehabilitated; hemodynamic findings were normal in all patients and the frequency of other transplant-associated complications was similar in both groups. In conclusion, heart transplantation is a valuable option for patients with PPCM and severe congestive heart failure that is unresponsive to conventional treatment.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Am Heart Jjournal_title
American heart journalauthors
Rickenbacher PR,Rizeq MN,Hunt SA,Billingham ME,Fowler MBdoi
10.1016/0002-8703(94)90051-5subject
Has Abstractpub_date
1994-05-01 00:00:00pages
1318-23issue
5eissn
0002-8703issn
1097-6744pii
0002-8703(94)90051-5journal_volume
127pub_type
杂志文章abstract::The Salt Substitute and Stroke Study is an ongoing 5-year large-scale cluster randomized trial investigating the effects of potassium-enriched salt substitute compared to usual salt on the risk of stroke. The study involves 600 villages and 20,996 individuals in rural China. Intermediate risk markers were measured in ...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
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更新日期:2020-03-01 00:00:00
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journal_title:American heart journal
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更新日期:2005-06-01 00:00:00
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journal_title:American heart journal
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更新日期:1987-09-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:1991-06-01 00:00:00
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更新日期:1991-10-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:2018-05-01 00:00:00
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更新日期:2014-01-01 00:00:00
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journal_title:American heart journal
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更新日期:1995-03-01 00:00:00
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更新日期:1993-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:1985-12-01 00:00:00
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更新日期:2003-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2000-12-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 评论
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更新日期:2004-04-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2003-03-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2009-05-01 00:00:00
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journal_title:American heart journal
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更新日期:1996-02-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(93)90405-x
更新日期:1993-09-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2013.07.010
更新日期:2013-10-01 00:00:00