Abstract:
BACKGROUND:Rheumatic disease and heart disease share common underpinnings involving inflammation. The high levels of inflammation that characterize rheumatic diseases provide a "natural experiment" to help elucidate the mechanisms by which inflammation accelerates heart disease. Rheumatoid arthritis (RA) is the most common of the rheumatic diseases and has the best studied relationships with heart disease. METHODS:A review of current literature on heart disease and RA was conducted. RESULTS:Patients with RA have an increased risk of developing heart disease that is not fully explained by traditional cardiovascular risk factors. Therapies used to treat RA may also affect the development of heart disease; by suppressing inflammation, they may also reduce the risk of heart disease. However, their other effects, as in the case of steroids, may increase heart disease risk. CONCLUSIONS:Investigations of the innate and adaptive immune responses occurring in RA may delineate novel mechanisms in the pathogenesis of heart disease and help identify novel therapeutic targets for the prevention and treatment of heart disease.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Crowson CS,Liao KP,Davis JM 3rd,Solomon DH,Matteson EL,Knutson KL,Hlatky MA,Gabriel SEdoi
10.1016/j.ahj.2013.07.010subject
Has Abstractpub_date
2013-10-01 00:00:00pages
622-628.e1issue
4eissn
0002-8703issn
1097-6744pii
S0002-8703(13)00448-1journal_volume
166pub_type
杂志文章,评审abstract:BACKGROUND:The presence of depression after an acute coronary syndrome (ACS) is associated with worse prognosis and lower adherence to risk-reducing behaviors. We reported earlier that an enhanced depression care intervention reduces depression symptoms and major adverse cardiac events. This study evaluates the impact ...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
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更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:The few available studies of the Centers for Medicare and Medicaid Services Hospital Inpatient Quality Reporting (IQR) care process indicators have not linked receipt of recommended care processes in heart failure (HF) with lower mortality. Because the Veterans Health Administration (VHA) also tracks hospita...
journal_title:American heart journal
pub_type: 杂志文章
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更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:This study assessed the feasibility of a 12-week program of exercise, with and without intramuscular testosterone supplementation, in male patients with chronic heart failure (CHF) and low testosterone status and collected preliminary data for key health outcomes. METHODS:Male patients with CHF (n = 41, age...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
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更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Recently, long (> or =20 mm) coronary stents were introduced for clinical use. They are intended as an alternative to multiple conventional stents to treat extensive dissections or suboptimal results of long lesions after balloon angioplasty. METHODS:In a total of 113 such consecutive vessels in 107 patient...
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abstract::The normal pattern of the myocardial sympathetic innervation was studied in 15 subjects using single photon emission computed tomography (SPECT) gamma scintigraphy with iodine 123-labeled meta-iodobenzylguanidine (I123MIBG). Seven young subjects (mean age 29.4 +/- 7.5 years SD) with supraventricular tachycardia and ei...
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pub_type: 杂志文章,多中心研究
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abstract::The distinction between idiopathic dilated cardiomyopathy and myocarditis is controversial, both clinically and pathologically. To increase diagnostic accuracy and provide prognostic information, we prospectively tested the routine application of immunofluorescence and electron microscopy in endomyocardial biopsy eval...
journal_title:American heart journal
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journal_title:American heart journal
pub_type: 杂志文章
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journal_title:American heart journal
pub_type: 杂志文章
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journal_title:American heart journal
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:2005-08-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:1993-07-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,评审
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更新日期:1991-02-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:1988-09-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:2011-11-01 00:00:00
abstract::Congenitally corrected transposition of the great arteries (ccTGA) is associated with various types of arrhythmia, including supraventricular tachycardia (SVT) and complete atrioventricular block (cAVB). Our study aims to characterize the arrhythmia burden, associated risk factors, arrhythmia mechanisms, and the long-...
journal_title:American heart journal
pub_type: 杂志文章
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更新日期:2021-01-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2003-09-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2016-04-01 00:00:00
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journal_title:American heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2000-04-01 00:00:00
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更新日期:2004-10-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:2002-11-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:1993-05-01 00:00:00
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journal_title:American heart journal
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更新日期:2010-12-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:2012-09-01 00:00:00
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journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2000-04-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(05)80050-x
更新日期:1990-03-01 00:00:00