Abstract:
BACKGROUND:We evaluated the influence of peak respiratory exchange ratio (pRER), as an index of effort adequacy, on peak VO2 prognostic reliability in patients with chronic heart failure (CHF) and reduced exercise capacity, whose peak VO2 may be underestimated because of poor patient motivation.
METHODS:A cardiopulmonary exercise test was performed in 570 patients with CHF (age 60 +/- 10 years, ejection fraction 26% +/- 7%, New York Heart Association class 2.2 +/- 0.6), 193 of whom had a peak VO2 that was >10 but journal_name journal_title authors doi subject pub_date pages issue eissn issn pii journal_volume pub_type
abstract::Two-dimensional contrast perfusion echocardiography was performed in 14 patients who underwent percutaneous transluminal coronary angioplasty to test the efficacy of this new technique for defining the area at risk of dyskinesis during acute coronary occlusion. In nine patients (group A) selective coronary injection o...
journal_title:American heart journal
pub_type: 临床试验,杂志文章
doi:10.1016/0002-8703(87)90744-7
更新日期:1987-09-01 00:00:00
abstract:OBJECTIVE:To examine the safety and efficacy of cangrelor in patients with single-vessel disease (SVD) and multi-vessel disease (MVD). BACKGROUND:Cangrelor, an intravenous, rapidly acting P2Y12 inhibitor, is superior to clopidogrel in reducing ischemic events among patients receiving percutaneous coronary intervention...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2017.02.031
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Compared with men, women have more evidence of myocardial ischemia with no obstructive coronary artery disease. Although low endogenous estrogen levels are associated with endothelial dysfunction, the role of low-dose hormone therapy has not been fully evaluated. We postulate that a 12-week duration of low-d...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2010.03.024
更新日期:2010-06-01 00:00:00
abstract::The serum chromium in 45 subjects with no clinical evidence of ischemic heart disease was found to be 1.71 parts per billion (ppb) (S.E. +/- 0.14). In 34 patients with a previously documented myocardial infarction, it was 1.84 ppb (S.E. +/- 0.18). The difference was not significant nor was there any difference with ag...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(80)90734-6
更新日期:1980-05-01 00:00:00
abstract:BACKGROUND:A previous randomized controlled trial evaluating the use of spironolactone in heart failure patients reported a low risk of hyperkalemia (2%) and renal insufficiency (0%). Because treatments for heart failure have changed since the benefits of spironolactone were reported, the prevalence of these complicati...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.10.005
更新日期:2004-12-01 00:00:00
abstract::The MAPHY Study was conducted to investigate whether metoprolol, a relatively beta 1-selective beta-blocker, given as initial antihypertensive treatment, would lower cardiovascular complications of high blood pressure to a greater extent than do thiazide diuretics as initial treatment at similar blood pressure control...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-8703(88)90112-3
更新日期:1988-07-01 00:00:00
abstract::Critical limb ischemia is associated with excessively high risk for cardiovascular events, including myocardial infarction and death. Additionally, in this patient population non-invasive evaluation of coronary artery disease is limited due to (1) inability of exercise testing, (2) frequent occurrence of balanced isch...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2019.05.005
更新日期:2019-08-01 00:00:00
abstract::To evaluate whether the identification of the different types of relations between premature ventricular contractions (PVCs) and the preceding sinus cycle length is capable of predicting the effect of beta-blockers on the PVCs themselves, 55 patients (43 men, 12 women, mean age 52.6 +/- 15.6 years) with different card...
journal_title:American heart journal
pub_type: 临床试验,杂志文章
doi:10.1016/s0002-8703(96)90529-3
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:The effect of raloxifene on aortic elasticity in healthy postmenopausal women is unknown. The purpose of the present study was to examine the effect of raloxifene on aortic elasticity and cardiovascular structure and function in healthy postmenopausal women. METHODS:A randomized, crossover, double-blind, pl...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2005.02.020
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Percutaneous pulmonary valve implantation (PPVI) has been introduced as therapy for right ventricular (RV) to pulmonary artery conduit dysfunction in patients with congenital heart disease. It has been shown that RV systolic function improved early after PPVI. The effects of PPVI on RV diastolic function and...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2009.04.023
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:This study investigates whether pioglitazone reduces neointimal hyperplasia after coronary stenting in nondiabetic patients with metabolic syndrome (MS) using intravascular ultrasound (IVUS). Pioglitazone, a novel insulin-sensitizing thiazolidinedione, has been shown to reduce neointimal hyperplasia after co...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2007.02.022
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:Vascular wall shear stress (WSS) has been implied in the pathogenesis of atherosclerosis and vascular remodeling. Our aim was to calculate WSS after balloon angioplasty and evaluate its predictive value for long-term outcome. METHODS:WSS was calculated proximal to, in, and distal to the lesion after angiogr...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2002.123110
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation (AF) is associated with increased risk of death, thromboembolic complications, and a lowered quality of life. Despite this burden, pharmacologic agents for prevention of AF in patients who achieved normal sinus rhythm are of limited utility, mostly because of serious and frequent side eff...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2008.10.027
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine in pediatric Duchenne (DMD) and Becker muscular dystrophy (BMD) or other dilated cardiomyopathies (ODCM) whether outcomes differ by diagnosis. BACKGROUND:Children with dilated cardiomyopathy are treated as a single undifferentiated group. METHODS:This cohort study of 1...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2008.01.018
更新日期:2008-06-01 00:00:00
abstract::Ventricular late potentials at the end of the surface QRS, detected on the signal-averaged electrocardiogram (SAECG) have been shown to be markers for spontaneous and/or inducible ventricular tachycardia (VT) in patients with coronary artery disease (CAD). We examined the correlations between electrophysiologic study ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(88)90884-8
更新日期:1988-04-01 00:00:00
abstract::A population of 2955 patients admitted to the hospital with acute myocardial infarction (AMI) was followed for 1 year after AMI or until death. Smokers as compared to nonsmokers were over 10 years younger (p less than 0.001) and had a lower prevalence of hypertension (p less than 0.01), congestive heart failure (p les...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(85)90071-7
更新日期:1985-09-01 00:00:00
abstract::Percutaneous transluminal coronary recanalization, a new therapeutic procedure used in acute myocardial infarction, offers significant reduction in mortality, as well as more effective limitation of the zone of infarction than has been possible with other pharmacologic treatment employed in the past. The risk of coron...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(81)90649-9
更新日期:1981-12-01 00:00:00
abstract::Changes in conduction times induced by ischemia (delta CT) have been shown to be quantitatively related to genesis of spontaneous ischemic ventricular fibrillation (VF). We studied conduction delay encountered by premature impulses in epicardium and endocardium in both anterograde and retrograde directions during isch...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(81)90308-2
更新日期:1981-09-01 00:00:00
abstract::The Lown grading system uses three levels of frequency and four complex features to grade ventricular arrhythmias. The seven Lown grades are mutually exclusive (a patient can be in only one grade) and hierarchical (higher grades indicate increased likelihood of death). We evaluated the ability of the Lown arrhythmia g...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(80)90217-3
更新日期:1980-12-01 00:00:00
abstract:BACKGROUND:In patients hospitalized with acutely decompensated heart failure, unresolved signs and symptoms of fluid overload have been consistently associated with poor outcomes. Regardless of dosing and type of administration, intravenous loop diuretics have not reduced heart failure events or mortality in patients w...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2015.05.019
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:The Fontan operation results in a circulation that is dependent on low pulmonary vascular resistance to maintain an adequate cardiac output. Medical therapies that lower pulmonary vascular resistance may augment cardiac output and improve long-term outcomes. OBJECTIVES:This phase I/II clinical trial conduct...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2017.02.030
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:High-sensitivity C-reactive protein (hsCRP) is promoted as an independent predictor of atherosclerotic risk. In addition, cardiorespiratory fitness is inversely related to hsCRP in single-sex cross-sectional analyses. Our objective was to determine if modulating fitness with exercise training imposes changes...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2006.04.019
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Three landmark trials involving 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) were published between 1994 and 1996 (the Scandinavian Simvastatin Survival Study [4S], the West of Scotland Coronary Prevention Study, and the Cholesterol and Recurrent Events trial). These trials provided e...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2001.115587
更新日期:2001-06-01 00:00:00
abstract::Compared with pathologic studies coronary angiography is a relatively insensitive technique to detect early atherosclerosis. Coronary angioscopy is a new technique providing direct information on luminal vessel surface. To determine whether coronary angioscopy may detect the presence of atherosclerotic disease on angi...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(95)90198-1
更新日期:1995-11-01 00:00:00
abstract::In order to study the origin of the basal systolic murmurs in mitral stenosis, left and right heart catheterization was performed in 18 patients with mitral stenosis using intracardiac phonocardiography. Our data revealed that the basal systolic murmurs originated in the aorta, the pulmonary artery, and the outflow tr...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(78)90163-1
更新日期:1978-10-01 00:00:00
abstract::Pregnancy has been discouraged in patients with peripartum cardiomyopathy (PPCM) to avoid the risk of precipitating recurrent or progressive left ventricular dysfunction. We assessed left ventricular size and contractile function using echocardiography in four PPCM patients prior to pregnancy, during the third trimest...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90025-d
更新日期:1991-06-01 00:00:00
abstract::The Institute of Medicine report on the frequency and consequences of medical errors in clinical practice has stimulated physicians to evaluate current practice and means of improving medical care. In the treatment of patients with acute myocardial infarction, previous studies have found that dosing of fibrinolytic th...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1067/mhj.2000.111605
更新日期:2000-12-01 00:00:00
abstract:PURPOSE:Viable myocardium after acute myocardial infarction may be characterized by magnetic resonance imaging (MRI) either by demonstration of recovery of wall motion under dobutamine stress or by perfusion patterns after contrast medium administration. This study examines the relation between the two techniques. MAT...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(98)70049-3
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Plasma levels of brain natriuretic peptide (BNP) are increased in patients with left heart failure. In patients with severe pulmonary embolism (PE), primary right ventricular (RV) dysfunction is frequent. Little is known about BNP secretion in acute RV failure. METHODS:We prospectively studied 50 consecutiv...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(03)00528-3
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Moderate alcohol drinking and marine omega-3 fatty acids (omega3) have both been associated with low mortality from coronary heart disease (CHD). However, there is little data evaluating the interactions of wine ethanol drinking with omega3 in CHD patients. METHODS:The relationships between wine drinking an...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2007.08.009
更新日期:2008-01-01 00:00:00