当前位置： SCI文献检索 > AMERICAN HEART JOURNAL期刊下所有文献 > The 6-minute walk test: how important is the learning effect?

The 6-minute walk test: how important is the learning effect?

Abstract：

BACKGROUND:The 6-minute walk test is a submaximal exercise test that is widely used as an outcomes measure in clinical trials and cardiopulmonary rehabilitation. An initial learning effect with repeated administration is well documented, but it is unknown whether this learning effect persists with time. METHODS:This study was designed to determine whether the learning effect persists after 2 months. Fifty healthy adults (mean age, 30.6 years; 48% men, 82% white) unfamiliar with the 6-minute walk test completed 3 walks at baseline (walks 1-3) and 3 walks at follow-up (walks 4-6). Height, weight, and self-reported physical activity were assessed at both points. Distances walked during the 6 walks were compared with a general linear model for repeated measures with post-hoc pairwise comparisons corrected by the Bonferroni method. A P value <.05 was considered to be significant. RESULTS:The distance walked increased significantly between walks 1 and 3 (2046 +/- 228 ft to 2194 +/- 266 ft, P <.05). There was no difference in distance walked between walks 3 and 4, which were conducted 2 months apart. The distance walked increased significantly between walks 4 and 6 (2201 +/- 233 ft to 2285 +/- 257 ft, P <.05). The overall learning effect was inversely correlated with distance walked at walk 1, but was unrelated to age, sex, height, weight, or physical activity level. CONCLUSION:The initial learning effect is maintained during a 2-month period. A more modest additional learning effect occurs during the follow-up walks. Both learning effects should be taken into account when using the 6-minute walk test as an outcomes measure.

journal_name

Am Heart J

journal_title

American heart journal

authors

Wu G,Sanderson B,Bittner V

doi

10.1016/S0002-8703(03)00119-4

subject

Has Abstract

pub_date

2003-07-01 00:00:00

pages

129-33

issue

1

eissn

0002-8703

issn

1097-6744

pii

S0002870303001194

journal_volume

146

pub_type

杂志文章

相关文献

AMERICAN HEART JOURNAL文献大全
  • Response of reperfusion-salvaged, stunned myocardium to inotropic stimulation.

    abstract：:The purpose of this study was to determine whether myocardium salvaged by reperfusion following coronary occlusion could respond to inotropic stimulation by dopamine. Mongrel dogs underwent a 2-hour occlusion of the proximal left anterior descending coronary artery, followed by reperfusion for 5 or 28 hours. Dopamine ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(84)90126-1

    authors： Ellis SG,Wynne J,Braunwald E,Henschke CI,Sandor T,Kloner RA

    更新日期：1984-01-01 00:00:00

  • Cost effectiveness of a gene expression score and myocardial perfusion imaging for diagnosis of coronary artery disease.

    abstract：BACKGROUND:Over 3 million patients annually present with symptoms suggestive of obstructive coronary artery disease (oCAD) in the United States (US), but a cardiac etiology is found in as few as 10% of cases. Usual care may include advanced cardiac testing with myocardial perfusion imaging (MPI), with attendant radiati...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2014.02.005

    authors： Phelps CE,O'Sullivan AK,Ladapo JA,Weinstein MC,Leahy K,Douglas PS

    更新日期：2014-05-01 00:00:00

  • Effects of postural changes on left atrial function in patients with hypertrophic cardiomyopathy.

    abstract：BACKGROUND:We assessed left atrial function in normal subjects and in patients with hypertrophic cardiomyopathy (HCM) by using Doppler echocardiography at the supine position and after sudden standing. METHODS AND RESULTS:Twenty-seven patients with hypertrophic obstructive cardiomyopathy (HOCM), 17 patients with HCM, ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(98)70153-x

    authors： Dernellis J,Tsiamis E,Stefanadis C,Pitsavos C,Toutouzas P

    更新日期：1998-12-01 00:00:00

  • How to use ACE-inhibitors, beta-blockers, and newer therapies in AMI.

    abstract：:Besides reperfusion treatment, which is the most powerful approach to the underlying pathophysiological cause of myocardial infarction, adjunctive therapies should be considered to reduce clinical symptoms, and improve left ventricular function and mortality rates. Randomized clinical trials and overviews of adjunctiv...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/s0002-8703(99)70341-8

    authors： Maggioni AP,Latini R

    更新日期：1999-08-01 00:00:00

  • Tamoxifen is not detrimental to endothelial function in postmenopausal women with breast cancer.

    abstract：BACKGROUND:Tamoxifen has mixed estrogen agonist and antagonist properties in estrogen-regulated tissues. Its effect on the cardiovascular system is not well defined. We carried out a study to investigate the effect of tamoxifen on peripheral vascular endothelial function. METHODS:Three groups of postmenopausal women (...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1067/mhj.2001.117323

    authors： Ong PJ,Linardou H,Graham HA,Savage P,Hayward CS,Coombes RC,Collins P

    更新日期：2001-10-01 00:00:00

  • Rapid, sensitive detection of myoglobulinemia by improved counterimmunoelectrophoresis in cases of acute myocardial infarction.

    abstract：:A counterimmunoelectrophoresis technique for detection of serum myoglobin (Mb) was improved using non-ionic polymer dextran. Precipitin lines were graded according to their strength, which was ascertained by radioimmunoassay data. By this method, serum Mb in concentrations of 500 ng./ml. before stain and of 200 ng./ml...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(78)90084-4

    authors： Hiramori K,Sumiyoshi T,Motegi S,Honda T,Kimata S,Hirosawa K,Kawai H,Kondo A,Iwaasa M,Miyoshi K

    更新日期：1978-08-01 00:00:00

  • Decreased incidence of antiarrhythmic drug efficacy at electrophysiologic study associated with the use of a third extrastimulus.

    abstract：:Drug trials during electrophysiologic study were performed in 166 patients with sustained ventricular tachycardia (VT) or ventricular fibrillation. In the first 21 patients (group I), a maximum of two extrastimuli was used. In 145 subsequent patients (group II), drug efficacy was assessed using three extrastimuli if o...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(82)90432-x

    authors： Swerdlow CD,Blum J,Winkle RA,Griffin JC,Ross DL,Mason JW

    更新日期：1982-11-01 00:00:00

  • The role of transesophageal echocardiography in cardiac donor screening.

    abstract：:Transthoracic echocardiography has played a useful role in the screening of cardiac transplant donors. However, transthoracic echocardiograms may be suboptimal in many patients on ventilators. The role of transesophageal echocardiography in cardiac donor screening is unknown. Therefore we compared the potential benefi...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(93)90758-2

    authors： Stoddard MF,Longaker RA

    更新日期：1993-06-01 00:00:00

  • Use of intensive lipid-lowering therapy in patients hospitalized with acute coronary syndrome: An analysis of 65,396 hospitalizations from 344 hospita participating in Get With The Guidelines (GWTG).

    abstract：OBJECTIVES:The study aimed to analyze the use of intensive lipid-lowering therapy (I-LLT) at discharge in a broad population of patients hospitalized with acute coronary syndrome (ACS). BACKGROUND:Early and intensive statin therapy in ACS has been shown to reduce cardiovascular morbidity and mortality. Utilization and...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ahj.2010.12.014

    authors： Javed U,Deedwania PC,Bhatt DL,Cannon CP,Dai D,Hernandez A,Peterson ED,Fonarow GC

    更新日期：2011-02-01 00:00:00

  • Transseptal left heart catheterization with a Swan-Ganz flow-directed catheter: review of 173 studies.

    abstract：:Of 178 transseptal left heart catheterizations performed, 173 successful cases are reported, with the use of a Swan-Ganz, flow-directed, balloon-tipped catheter. By means of a modified Brockenbrough technique, which is described in detail, a 10F Teflon tube (3.3 mm outside diameter) was inserted into the left atrium. ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(85)90603-9

    authors： Bagger JP,Sennels F,Vejby-Christensen H,Rasmussen K,Thomsen PE,Gøtzsche H

    更新日期：1985-02-01 00:00:00

  • Prenatal diagnosis of atrioventricular canal malformations with up-to-date echocardiographic technology: report of 14 cases.

    abstract：:Fourteen fetuses with atrioventricular canal malformations were examined by two-dimensional echocardiography, pulsed-wave Doppler echocardiography, and color Doppler flow mapping. Eleven fetuses had complete and three fetuses had partial atrioventricular canal malformations. Nonimmune hydrops fetalis was associated wi...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(91)90156-c

    authors： Gembruch U,Knöpfle G,Chatterjee M,Bald R,Redel DA,Födisch HJ,Hansmann M

    更新日期：1991-05-01 00:00:00

  • Fondaparinux versus Enoxaparin in non-ST-elevation acute coronary syndromes: short-term cost and long-term cost-effectiveness using data from the Fifth Organization to Assess Strategies in Acute Ischemic Syndromes Investigators (OASIS-5) trial.

    abstract：BACKGROUND:The study aimed to compare the short-term costs and long-term cost-effectiveness of 2 antithrombotics, fondaparinux and enoxaparin, for non-ST-elevation acute coronary syndrome in the United States. METHODS:It was based on a large randomized trial of 20,078 patients Fifth Organization to Assess Strategies i...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2009.02.017

    authors： Sculpher MJ,Lozano-Ortega G,Sambrook J,Palmer S,Ormanidhi O,Bakhai A,Flather M,Steg PG,Mehta SR,Weintraub W

    更新日期：2009-05-01 00:00:00

  • Effect of low doses of n-3 fatty acids on cardiovascular diseases in 4,837 post-myocardial infarction patients: design and baseline characteristics of the Alpha Omega Trial.

    abstract：BACKGROUND:Weekly fish consumption has been related to a lower risk of fatal coronary heart disease (CHD) and incident stroke in populations with a low fish intake. This relation has mainly been attributed to n-3 fatty acids in fish, that is, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). It is at present ...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ahj.2009.12.033

    authors： Geleijnse JM,Giltay EJ,Schouten EG,de Goede J,Oude Griep LM,Teitsma-Jansen AM,Katan MB,Kromhout D,Alpha Omega Trial Group.

    更新日期：2010-04-01 00:00:00

  • Quantitative Blush Evaluator accurately quantifies microvascular dysfunction in patients with ST-elevation myocardial infarction: comparison with cardiovascular magnetic resonance.

    abstract：BACKGROUND:After ST-elevation myocardial infarction (STEMI), microvascular obstruction (MVO) can be assessed using semiquantitative angiographic "blush" scores subject to interoperator variability. Quantitative Blush Evaluator (QuBE) is a free computer-calculated algorithm that evaluates myocardial blush on a continuou...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2011.04.014

    authors： Porto I,Hamilton-Craig C,De Maria GL,Vergallo R,Cautilli G,Galiuto L,Burzotta F,Leone AM,Niccoli G,Natale L,Bonomo L,Crea F

    更新日期：2011-08-01 00:00:00

  • Clinical status of patients removed from a transplant waiting list rivals that of transplant recipients at significant cost savings.

    abstract：:We retrospectively contrasted the medical outcome of patients removed from the heart transplant consideration list because of clinical improvement with that of transplant recipients. Of 60 patients awaiting transplantation, 18 were removed from the list (group A), and 42 required transplant or died (group B). Group A ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(96)90462-7

    authors： Levine TB,Levine AB,Goldberg AD,Tobes M,Narins B,Lesch M

    更新日期：1996-12-01 00:00:00

  • Depression and ischemic heart disease.

    abstract：:Major depression is a common comorbidity associated with ischemic heart disease (IHD). There is growing evidence that psychological stress in general and depression in particular predispose to cardiovascular disease. Persons who have mental stress during daily life are at twice the risk of myocardial ischemia, and pat...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1067/mhj.2000.109979

    authors： O'connor CM,Gurbel PA,Serebruany VL

    更新日期：2000-10-01 00:00:00

  • Prognostic significance of morphometric endomyocardial biopsy analysis in patients with idiopathic dilated cardiomyopathy.

    abstract：BACKGROUND:To date, considerable controversy exists on the prognostic significance of morphometric endomyocardial biopsy findings in patients with idiopathic dilated cardiomyopathy (IDC). METHODS:Quantitative analyses of interstitial structured tissue, myofibril volume fraction, and myocytic fiber diameters of left ve...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/S0002-8703(03)00148-0

    authors： Grimm W,Rudolph S,Christ M,Pankuweit S,Maisch B

    更新日期：2003-08-01 00:00:00

  • Pulmonary function in hypertensive patients treated with pindolol: a report of two studies.

    abstract：:Pulmonary function was measured serially in two separate randomized trials of pindolol in the treatment of essential hypertension. Patients with overt obstructive airways disease were excluded. In study 1, 131 hypertensive patients were randomized to placebo (31) and 15 mg (33), 30 mg (33), and 60 mg (34) of pindolol....

    journal_title：American heart journal

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-8703(82)90135-1

    authors： Hamilton BP,Hamilton J,Kirkendall WM

    更新日期：1982-08-01 00:00:00

  • Clinical evaluation of a prospective protocol for the timing of surgery in chronic aortic regurgitation.

    abstract：:Out of 160 prospectively followed patients with aortic regurgitation, the clinical courses of 53 patients with pure, severe, and chronic aortic regurgitation and without coronary artery disease who were selected for surgery on the basis of predefined criteria is discussed. Surgical criteria were either unequivocal sym...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(90)90023-q

    authors： Tornos MP,Permanyer-Miralda G,Evangelista A,Worner F,Candell J,Garcia-del-Castillo H,Soler-Soler J

    更新日期：1990-09-01 00:00:00

  • Prognostic significance of echocardiographically defined mitral regurgitation early after acute myocardial infarction.

    abstract：BACKGROUND:There are limited data regarding the clinical correlates and prognostic significance of echocardiographically defined mitral regurgitation (MR) early after acute myocardial infarction (MI). The current study addressed these issues. METHODS:Seven hundred thirty-seven patients with acute MI who underwent tran...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2005.01.020

    authors： Hillis GS,Møller JE,Pellikka PA,Bell MR,Casaclang-Verzosa GC,Oh JK

    更新日期：2005-12-01 00:00:00

  • Knowledge to action: Rationale and design of the Patient-Centered Care Transitions in Heart Failure (PACT-HF) stepped wedge cluster randomized trial.

    abstract：INTRODUCTION:Heart Failure (HF) is a common cause of hospitalization in older adults. The transition from hospital to home is high-risk, and gaps in transitional care can increase the risk of re-hospitalization and death. Combining health care services supported by meta-analyses, we designed the PACT-HF transitional ca...

    journal_title：American heart journal

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.ahj.2017.12.013

    authors： Van Spall HGC,Lee SF,Xie F,Ko DT,Thabane L,Ibrahim Q,Mitoff PR,Heffernan M,Maingi M,Tjandrawidjaja MC,Zia MI,Panju M,Perez R,Simek KD,Porepa L,Graham ID,Haynes RB,Haughton D,Connolly SJ

    更新日期：2018-05-01 00:00:00

  • Effect of perindopril in rat cardiac volume overload.

    abstract：:The aortocaval fistula is a classic model of pure cardiac volume overload in rats. This model is characterized by dilation of the ventricular cavities and eccentric cardiac hypertrophy. There are also changes in peripheral arterial flow: high flow in the proximal part of the aorta, upstream of the shunt, and low flow ...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(93)90929-4

    authors： Arnal JF,Philippe M,Laboulandine I,Michel JB

    更新日期：1993-09-01 00:00:00

  • The triglyceride-high-density lipoprotein axis: an important target of therapy?

    abstract：:Coronary heart disease is the single largest cause of morbidity and mortality in the United States. The link between elevated low-density lipoprotein cholesterol (LDL-C) levels and coronary heart disease (CHD) has been clearly established. However, triglycerides (TG) are increasingly believed to be independently assoc...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/j.ahj.2004.03.037

    authors： Szapary PO,Rader DJ

    更新日期：2004-08-01 00:00:00

  • Atrial septal aneurysms in infants and children.

    abstract：:Interatrial septal aneurysm (IASA) has been detected with increasing frequency since the advent of two-dimensional echocardiography (2DE). In this study, we investigated the prevalence, characteristics, and predisposing factors in IASA formation in 724 infants, children, and adolescents undergoing 2DE. Among this grou...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(87)90927-6

    authors： Wolf WJ,Casta A,Sapire DW

    更新日期：1987-05-01 00:00:00

  • Pathobiology of atherosclerosis and plaque complications.

    abstract：:To understand the process of atherosclerosis, the homeostatic and protective functions of the endothelium must be considered. The endothelium serves as the interface between blood flow and the vascular tissues. It normally regulates vascular tone and structure through the release of vasoactive substances and maintenan...

    journal_title：American heart journal

    pub_type： 杂志文章,评审

    doi：10.1016/0002-8703(94)90251-8

    authors： Dzau VJ

    更新日期：1994-12-01 00:00:00

  • Evaluation of mitral valve prolapse by four-dimensional echocardiography.

    abstract：:To observe the stereoscopic structure and the motion of the prolapsing mitral valve and its regurgitant jet in comparison with the normal mitral valve, four-dimensional (or dynamic three-dimensional) echocardiography of mitral valve apparatus was obtained in 20 patients with mitral valve prolapse and 10 unaffected sub...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/s0002-8703(97)70257-6

    authors： Cheng TO,Xie MX,Wang XF,Li ZA,Hu G

    更新日期：1997-01-01 00:00:00

  • Reproducibility of the proximal flow convergence method in mitral and tricuspid regurgitation.

    abstract：BACKGROUND:The follow-up of patients with mitral and tricuspid regurgitation is important for their clinical treatment. We aimed to evaluate the reproducibility of the flow convergence method in mitral and tricuspid regurgitation. METHODS:The proximal flow convergence region was imaged with color Doppler ultrasound sc...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/j.ahj.2003.11.006

    authors： Grossmann G,Hoffmeister A,Imhof A,Giesler M,Hombach V,Spiess J

    更新日期：2004-04-01 00:00:00

  • Is long-term pharmacist-managed anticoagulation service efficient? A pragmatic randomized controlled trial.

    abstract：BACKGROUND:Some pharmacist-managed anticoagulation services (PMAS) provide initial follow-up to patients on oral anticoagulant, who are transferred to their physician once they are stabilized. This may be as effective as and less expensive than long-term PMAS follow-up. METHODS:Once PMAS patients were stabilized and r...

    journal_title：American heart journal

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ahj.2008.02.009

    authors： Lalonde L,Martineau J,Blais N,Montigny M,Ginsberg J,Fournier M,Berbiche D,Vanier MC,Blais L,Perreault S,Rodrigues I

    更新日期：2008-07-01 00:00:00

  • Recent trends in the incidence rates of and death rates from atrial fibrillation complicating initial acute myocardial infarction: a community-wide perspective.

    abstract：BACKGROUND:Limited information is available about recent trends in the incidence and death rates from atrial fibrillation (AF) complicating acute myocardial infarction (AMI). The purpose of this study was to examine the impact and trends over time of AF complicating initial AMI. METHODS:We conducted a longitudinal stu...

    journal_title：American heart journal

    pub_type： 杂志文章,多中心研究

    doi：10.1067/mhj.2002.120410

    authors： Goldberg RJ,Yarzebski J,Lessard D,Wu J,Gore JM

    更新日期：2002-03-01 00:00:00

  • Effect of somatic nerve stimulation on coronary blood flow in anesthetized dogs.

    abstract：:Left circumflex coronary blood flow was increased significantly (20 per cent) during stimulation of somatic afferent fibers. The change in CBF was associated with significant increases in heart rate and arterial pressure and significant decrease in coronary vascular resistance. Controlling heart rate or preventing car...

    journal_title：American heart journal

    pub_type： 杂志文章

    doi：10.1016/0002-8703(79)90318-1

    authors： Kline RL

    更新日期：1979-07-01 00:00:00