Abstract:
:An extremely athletic 56-year-old male physician was found to have profound sinus bradycardia. His only symptom was markedly increased alertness while actively exercising. During pacemaker insertion he had an episode of prolonged sinus arrest terminated by a precordial thump. This case suggests that exercise can alter autonomic tone and increase cardiac output in sick sinus syndrome, causing improvement in possibly unrecognized, subtle, cerebral symptoms. It also appears that patients with profound sinus bradycardia should be given a substantial dose of atropine prior to pacemaker insertion in an effort to prevent prolonged sinus arrest.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Marmor BM,Black MMdoi
10.1016/0002-8703(80)90284-7subject
Has Abstractpub_date
1980-07-01 00:00:00pages
95-8issue
1eissn
0002-8703issn
1097-6744pii
0002-8703(80)90284-7journal_volume
100pub_type
杂志文章abstract::Histological study of the sinoatrial node (SAN) was performed in 111 patients in order to estabilsh correlations between the ECG findings and the anatomical lesions. This series includes both patients with sinus rhythm and patients with atrial arrhythmias. The results are as fololows: (a) the amount of nodal cells in ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(77)80070-7
更新日期:1977-06-01 00:00:00
abstract:BACKGROUND:Ibutilide is indicated for the acute termination of atrial fibrillation and atrial flutter. Recent work concludes that ibutilide activates a late inward sodium current that is blocked by nifedipine. Because calcium channel blockers are commonly used in patients with atrial fibrillation, it is important to ex...
journal_title:American heart journal
pub_type: 杂志文章,meta分析
doi:10.1067/mhj.2002.120156
更新日期:2002-01-01 00:00:00
abstract::Vessel dilator consisting of amino acids (a.a.) 31-67 and atrial natriuretic factor (ANF) composed of a.a. 99-126 of the 126 a.a. ANF prohormone circulate in humans and have potent vasodilatory properties. To determine whether these atrial natriuretic peptides are directly related to blood pressure in healthy normoten...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(95)90111-6
更新日期:1995-05-01 00:00:00
abstract::Complex coronary morphologic abnormalities with thrombus and ulceration have been recognized in acute ischemic syndromes by angiography, angioscopy, and autopsy. However, in vivo histopathologic correlates of unstable ischemic syndromes have not been described. The purpose of this study was to characterize intracorona...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(94)90612-2
更新日期:1994-09-01 00:00:00
abstract::To determine the frequency and significance of left ventricular wall motion abnormalities in patients without clinical evidence of myocardial infarction, we reviewed the two-dimensional echocardiograms of 252 patients who had no history or electrocardiographic evidence of myocardial infarction and who subsequently und...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90666-6
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND:The treatment of cocaine-related acute coronary syndromes presents unique challenges. Although percutaneous coronary intervention in cocaine abusers appears to be safe in the short term, longer-term outcomes have not been reported. We postulated that cocaine use would be associated with increased risk for st...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2007.04.004
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Limited data are available on the care of patients with acute severe hypertension requiring hospitalization. We characterized contemporary practice patterns and outcomes for this population. METHODS:STAT is a 25-institution, US registry of consecutive patients with acute severe hypertension (>180 mm Hg syst...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2009.07.020
更新日期:2009-10-01 00:00:00
abstract::Besides reperfusion treatment, which is the most powerful approach to the underlying pathophysiological cause of myocardial infarction, adjunctive therapies should be considered to reduce clinical symptoms, and improve left ventricular function and mortality rates. Randomized clinical trials and overviews of adjunctiv...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/s0002-8703(99)70341-8
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:Device-detected subclinical atrial fibrillation (AF) refers to infrequent, short-lasting, asymptomatic AF that is detected only with long-term continuous monitoring. Subclinical AF is common and associated with an increased risk of stroke; however, the risk of stroke with subclinical AF is lower than for cli...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2017.04.008
更新日期:2017-07-01 00:00:00
abstract::To determine the factors relating to prognosis, the records of 15 neonates with persistent prolongation of the QT interval on the electrocardiogram after the fourth day of life were reviewed. Patients were admitted for symptoms (syncope, cardiac failure, or seizures), abnormal auscultation with an irregular heart rate...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(92)90940-w
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:A large proportion of patients with heart failure (HF) have a large and poorly contracting left ventricle. The noninvasive recognition of the ischemic etiology of such patients is difficult, and for this purpose, usually patients undergo coronary angiography. It has been shown that cardiovascular magnetic re...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.03.068
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Type III hyperlipoproteinemia is characterized by the accumulation of chylomicron and very low density lipoprotein (VLDL) remnants. Individuals with this disorder have a high risk of premature atherosclerosis, and hypolipidemic drugs are useful in their management. METHODS:We compared, in a double-blind, pl...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-8703(99)70262-0
更新日期:1999-07-01 00:00:00
abstract::Inhibition of the enzyme that synthesizes thromboxanes may protect against the development of ventricular fibrillation (VF) during acute myocardial ischemia. This study was carried out to test this hypothesis with a new thromboxane synthetase inhibitor, and to extend the studies to alternative animal models of myocard...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(89)90622-4
更新日期:1989-04-01 00:00:00
abstract:BACKGROUND:According to a recent meta-analysis, parathyroid hormone (PTH) excess is associated with increased cardiovascular disease (CVD) risk, but existing studies are limited. We examined in a prospective study the association of PTH with the incidence of CVD, taking into account vitamin D and other confounding vari...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2014.04.017
更新日期:2014-09-01 00:00:00
abstract::In the Cardiovascular Measurement System (CMS) the edge-detection algorithm, which was primarily designed for the Philips digital cardiac imaging system (DCI), is applied to cinefilms. Comparative validation of CMS and DCI was performed in vitro and in vivo with intracoronary insertion of stenosis phantoms in anesthet...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(93)91045-g
更新日期:1993-08-01 00:00:00
abstract::We compared the effects of IV digoxin (0.04 mg/kg) and nitroprusside (NP) (1.2 and 1.8 microgram/kg/min) on left ventricular (LV) performance in six preinstrumented conscious dogs with 3 and 6 hours after digoxin administration (serum level, 3.5 +/- 0.6 ng/ml), there were no changes in heart rate, LV systolic (LVSP) a...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(82)90335-0
更新日期:1982-04-01 00:00:00
abstract::The addition of IAC to otherwise standard CPR provides for the application of external pressure over the abdomen in counterpoint to the rhythm of chest compression. Interposed abdominal compression is a simple manual technique that can supplement the use of adrenergic drugs to increase both coronary perfusion pressure...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(94)90132-5
更新日期:1994-02-01 00:00:00
abstract::Patients with intractable heart failure (New York Heart Association [NYHA] class III and IV) who were receiving maximal conventional treatment were enrolled in an outpatient program that included inotropic infusions, intensive patient education, and close follow-up. The effects of this approach to therapy were evaluat...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(96)90315-4
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND:In the United States, there continues to be debate about whether certain types of hospitals deliver improved patient outcomes. We sought to assess the association between hospital organizational characteristics and in-hospital outcomes for percutaneous coronary intervention (PCI). METHODS:Retrospective anal...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2011.10.010
更新日期:2012-02-01 00:00:00
abstract::Percutaneous coronary interventions have been performed for 20 years. Despite the success and progress of these interventions, abrupt vessel closure has been a dramatic adverse event of coronary interventions. Closure has frequently led to the major complications of death, myocardial infarction, and emergency coronary...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/s0002-8703(97)70069-3
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Cardiovascular disease is the leading cause of death among blacks and whites in the United States. Despite this, there are insufficient data on the long-term prognosis of black patients with coronary artery disease (CAD) as well as the major clinical related determinants of outcome. METHODS:We studied 22,61...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2010.06.014
更新日期:2010-10-01 00:00:00
abstract::The aim of this study was to determine whether paroxysmal atrial fibrillation (PAF) and/or restoration to sinus rhythm with electric or pharmacologic cardioversion induce modifications to the coagulation system. Thirty-five patients with PAF undergoing either electric (n = 11) or pharmacologic (n = 24) cardioversion w...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2000.108520
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Dilated and hypertrophic cardiomyopathies are primary myocardial diseases that cause considerable morbidity and mortality. Although these cardiomyopathies are clinically heterogeneous, genetic factors play an important role in their etiology and pathogenesis. The defects in the cardiac actin (ACTC) gene can ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2002.122514
更新日期:2002-06-01 00:00:00
abstract::Heart rate responses to three different procedures (amyl nitrite inhalation, standing up, and isoproterenol infusion), were studied before and during acute adrenergic beta blockade with intravenous propranolol in three normal and six hypertensive subjects. Propranolol decreased, but did not completely abolish, the hea...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(78)90125-4
更新日期:1978-07-01 00:00:00
abstract::The purpose of this investigation was to identify early left ventricular (LV) cineangiographic signs of myocardial damage and to study the evolution of the characteristic lesions in 126 chronic chagasic patients, divided into three groups. Group I patients had no clinical, ECG, or radiologic evidences of heart disease...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(82)90232-0
更新日期:1982-09-01 00:00:00
abstract:BACKGROUND:The study evaluates whether Optison used during dobutamine stress echocardiography (DSE) will improve endocardial border definition and whether this will translate to an improvement in sensitivity and specificity of the test in patients with poor echocardiographic windows. DSE is extremely valuable in the wo...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2001.117608
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Randomized trials have established efficacy of clopidogrel in various types of acute coronary syndromes (ACS). The objective of this study was to examine the temporal trends and patterns of early clopidogrel use (within the first 24 hours of hospitalization) across the spectrum of patients with ACS in Canada...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2009.01.002
更新日期:2009-04-01 00:00:00
abstract::The primary objective of this study was to apply a sophisticated coagulation monitoring system including estimation of the concentration of prothrombin fragment 1 + 2 (PTF 1 + 2) and the activity of prothrombin (coagulation factor II or FII) to cases of stent implantation and to compare the results with those of stand...
journal_title:American heart journal
pub_type: 临床试验,杂志文章
doi:10.1016/0002-8703(95)90433-6
更新日期:1995-08-01 00:00:00
abstract::To evaluate the stability of precordial ST-segment mapping techniques in assessing ischemic myocardial injury, we studied 28 patients with acute anterior myocardial infarction using a 49-lead electrocardiographic system (1 mV. = 10 mm.). The sum of ST elevations in millimeters was taken as an index of ischemic injury,...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(77)80011-2
更新日期:1977-05-01 00:00:00
abstract:BACKGROUND:Advanced age is a well-established prognostic risk factor after acute myocardial infarction (AMI), yet approximately 10% of MIs occur in patients <45 years. We examined characteristics, cardiovascular outcomes, and the influence of risk factors on outcomes in young survivors of AMI. METHODS:Fourteen thousan...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2007.11.016
更新日期:2008-04-01 00:00:00