Acute coronary occlusion occurring after successful percutaneous transluminal coronary angioplasty: temporal relationship to discontinuation of anticoagulation.

Abstract:

:The incidence and prognosis of acute coronary reocclusion occurring after patients had left the catheterization laboratory following a successful percutaneous transluminal coronary angioplasty (PTCA) procedure and the temporal relation of this event to the discontinuation of systemic heparin administration were analyzed in a series of 1238 consecutive patients. Acute reocclusion, 1 to 96 hours after successful PTCA, occurred in 22 of 1238 patients (1.8%). Patients undergoing PTCA in the setting of acute myocardial infarction were excluded. Out of 22 patients, 15 had a nonocclusive dissection and four had evidence of small intracoronary thrombus immediately post-PTCA, with no evidence of flow disturbance. Acute reocclusion occurred within 5 hours of heparin discontinuation in 12 patients or while they were receiving inadequate anticoagulation (four patients). In 16 of 22 (73%) patients, acute reocclusion was temporally related to a time of diminished anticoagulation. Redilation was attempted in 14 patients and was ultimately successful in five patients (36%). Ten patients required coronary artery bypass surgery and three patients died. Our findings suggest that acute reocclusion after an initially successful PTCA has a poor outcome and seems to be temporally related to the loss of effective anticoagulation in most of these patients. It is advisable to discontinue heparin infusion at a time when facilities for urgent revascularization are available.

journal_name

Am Heart J

journal_title

American heart journal

authors

Gabliani G,Deligonul U,Kern MJ,Vandormael M

doi

10.1016/0002-8703(88)90326-2

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

696-700

issue

3

eissn

0002-8703

issn

1097-6744

pii

0002-8703(88)90326-2

journal_volume

116

pub_type

杂志文章
  • Predictive value of immunofluorescence and electron microscopic evaluation of endomyocardial biopsies in the diagnosis and prognosis of myocarditis and idiopathic dilated cardiomyopathy.

    abstract::The distinction between idiopathic dilated cardiomyopathy and myocarditis is controversial, both clinically and pathologically. To increase diagnostic accuracy and provide prognostic information, we prospectively tested the routine application of immunofluorescence and electron microscopy in endomyocardial biopsy eval...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(87)90180-3

    authors: Hammond EH,Menlove RL,Anderson JL

    更新日期:1987-11-01 00:00:00

  • Dalteparin in combination with abciximab during percutaneous coronary intervention.

    abstract:BACKGROUND:Despite proved efficacy for either dalteparin or platelet glycoprotein IIb/IIIa blockade in improving clinical outcomes of patients with non-ST-segment elevation acute coronary syndromes, algorithms guiding concomitant therapy with these agents have not been devised. The purpose of this study was to assess a...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1067/mhj.2001.113217

    authors: Kereiakes DJ,Kleiman NS,Fry E,Mwawasi G,Lengerich R,Maresh K,Burkert ML,Aquilina JW,DeLoof M,Broderick TM,Shimshak TM

    更新日期:2001-03-01 00:00:00

  • Trends in outcomes among older patients with non-ST-segment elevation myocardial infarction.

    abstract:OBJECTIVES:The objective of this study is to assess trends in evidence-based therapy use and short- and long-term mortality over time among older patients with non-ST-segment elevation myocardial infarction (NSTEMI). BACKGROUND:With the prevalence of national quality improvement efforts, the use of evidence-based ther...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2013.10.008

    authors: Chin CT,Wang TY,Chen AY,Mathews R,Alexander KP,Roe MT,Peterson ED

    更新日期:2014-01-01 00:00:00

  • The evolving costs of intracoronary stents.

    abstract:BACKGROUND:As stenting practice has evolved to include greater numbers of stents and adjunctive balloon catheters per case, concern has focused on the increasing costs of equipment for the delivery of stents. METHODS AND RESULTS:To evaluate temporal changes in costs of intracoronary stenting, we examined total costs, ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(98)70193-0

    authors: Vaitkus PT,Adele C,Wells SK,Zehnacker JP

    更新日期:1998-07-01 00:00:00

  • Safety, feasibility, and prognostic implications of pharmacologic stress echocardiography in 1482 patients evaluated in an ambulatory setting.

    abstract:BACKGROUND:The outpatient prognostic assessment of coronary artery disease (CAD) by exercise electrocardiography has limitations, including the feasibility of the test and its low positive predictive value in several clinical conditions. In the current study we investigated the safety, feasibility, and prognostic value...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2001.113997

    authors: Cortigiani L,Picano E,Coletta C,Chiarella F,Mathias W,Gandolfo N,De Alcantara M,Mazzoni V,Gensini GF,Landi P,Echo Persantine International Cooperative (EPIC) Study Group.,Echo Dobutamine International Cooperative (EDIC) Study Group

    更新日期:2001-04-01 00:00:00

  • Validation of a specific activity questionnaire to estimate exercise tolerance in patients referred for exercise testing.

    abstract:BACKGROUND:Physical activity and symptom questionnaires have been used as surrogates for exercise testing to estimate a patient's functional capacity and to individualize an exercise testing protocol in accordance with exercise testing guidelines. To validate these approaches, they must be compared with measured oxygen...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2001.118740

    authors: Myers J,Bader D,Madhavan R,Froelicher V

    更新日期:2001-12-01 00:00:00

  • Exercise-induced alterations of signal-averaged electrocardiograms in marathon runners.

    abstract::Late potentials have been shown to predict malignant ventricular arrhythmias and sudden cardiac death. To determine whether prolonged, strenuous activity is associated with the development of ventricular late potentials, signal-averaged electrocardiography was performed on 30 marathon runners before, immediately after...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(89)90010-0

    authors: Smith GS,Vacek JL,Wilson DB,Hawkins JW,Boyer TA

    更新日期:1989-12-01 00:00:00

  • Correlation of abnormal Q waves, coronary pathology, and ventricular contractility.

    abstract::Four hundred and ninety-two patients with coronary artery disease underwent analysis of their electrocardiograms, coronary arteriograms, and ventriculograms. Significant Q-waves were correlated with critical coronary occlusions (greater than or equal 75 per cent obstruction) and ventricular contractility. It was found...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(75)90425-1

    authors: Gottlieb RS,Duca PR,Kasparian H,Scariato A,Brest AN

    更新日期:1975-10-01 00:00:00

  • Direct pharmacologic and osmolal effects of contrast media on the mechanics of heart muscle isolated from cats.

    abstract::We studied 56 right ventricular papillary muscles isolated from cats to determine whether the direct mechanical effects of contrast media are due to their pharmacologic action or to the hyperosmolality caused by them. A 10% solution of Renografin-76 abruptly decreased force 22% below control, then slowly increased it ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(84)90550-7

    authors: Chuck LH,Refsum H,Rouleau JL,Mathey D,Sievers RE,Parmley WW

    更新日期:1984-07-01 00:00:00

  • Incidence and natural history of coronary artery aneurysm developing after drug-eluting stent implantation.

    abstract:AIMS:There is a growing concern about the occurrence of coronary artery aneurysms (CAAs) after drug-eluting stent (DES) implantation and their long-term course. We assessed the occurrence and the factors affecting the long-term outcome of DES-associated CAA. METHODS AND RESULTS:We analyzed 3,612 consecutive patients (...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2010.07.013

    authors: Ahn CM,Hong BK,Kim JY,Min PK,Yoon YW,Lee BK,Kwon HM,Kim JS,Ko YG,Choi D,Hong MK,Jang Y,Shim WH,Cho SY,Kim BK,Oh S,Jeon DW,Yang JY,Jung JH

    更新日期:2010-11-01 00:00:00

  • Interactions of wine drinking with omega-3 fatty acids in patients with coronary heart disease: a fish-like effect of moderate wine drinking.

    abstract:BACKGROUND:Moderate alcohol drinking and marine omega-3 fatty acids (omega3) have both been associated with low mortality from coronary heart disease (CHD). However, there is little data evaluating the interactions of wine ethanol drinking with omega3 in CHD patients. METHODS:The relationships between wine drinking an...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2007.08.009

    authors: de Lorgeril M,Salen P,Martin JL,Boucher F,de Leiris J

    更新日期:2008-01-01 00:00:00

  • Novel antiplatelet therapies for treatment of patients with ischemic heart disease: inhibitors of the platelet glycoprotein IIb/IIIa integrin receptor.

    abstract::Blood platelets play essential roles in normal coagulation and in coronary atherosclerotic disease and its complications. Various antiplatelet therapies, including aspirin, ticlopidine, and dipyridamole, have been developed for use in patients with known coronary artery artery disease to prevent ischemic complications...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/0002-8703(95)90091-8

    authors: Frishman WH,Burns B,Atac B,Alturk N,Altajar B,Lerrick K

    更新日期:1995-10-01 00:00:00

  • Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: a systematic review and meta-analysis.

    abstract:BACKGROUND:Despite clopidogrel therapy, patients undergoing percutaneous coronary intervention (PCI) with stenting are at risk of recurrent coronary events. This could be partly explained by a reduced efficacy of clopidogrel to inhibit platelet aggregation, an ex vivo defined phenomenon called clopidogrel nonresponsive...

    journal_title:American heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ahj.2007.04.014

    authors: Snoep JD,Hovens MM,Eikenboom JC,van der Bom JG,Jukema JW,Huisman MV

    更新日期:2007-08-01 00:00:00

  • Efficacy of early invasive management post-fibrinolysis in men versus women with ST-elevation myocardial infarction: a subgroup analysis from Trial of Routine Angioplasty and Stenting after Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarctio

    abstract:BACKGROUND:The TRANSFER-AMI study demonstrated that early routine percutaneous coronary intervention post-fibrinolysis (pharmacoinvasive strategy) is superior to conservative management for ST-elevation myocardial infarction. However, it is not clear whether treatment efficacy differs between men and women. METHODS:In...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2012.05.022

    authors: Bhan V,Cantor WJ,Yan RT,Mehta SR,Morrison LJ,Heffernan M,Fitchett D,Džavík V,Ducas J,Borgundvaag B,Cohen EA,Goodman SG,Yan AT

    更新日期:2012-09-01 00:00:00

  • Diabetes status and racial differences in post-myocardial infarction mortality.

    abstract:BACKGROUND:Prior studies regarding the effect of racial status on post-myocardial infarction (MI) in subjects with diabetes have yielded conflicting results. We evaluated the effect of diabetes status on racial differences in post-MI mortality and morbidity for a 7-year period, from 1990 through 1997. METHODS:All pati...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2005.02.042

    authors: Kamalesh M,Subramanian U,Ariana A,Sawada S,Peterson E

    更新日期:2005-11-01 00:00:00

  • Clinical profile and outcome of restrictive cardiomyopathy in children.

    abstract::The clinical profile and outcome of idiopathic restrictive cardiomyopathy in a group of eight children are reviewed. There were six girls and two boys. Age at presentation was 4.0 +/- 2.6 years (range 1.3 to 9.5 years). All patients had evidence of congestive heart failure with systemic venous congestion. Right or lef...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(92)90814-c

    authors: Lewis AB

    更新日期:1992-06-01 00:00:00

  • Effect of raloxifene on aortic elasticity in healthy postmenopausal women.

    abstract:BACKGROUND:The effect of raloxifene on aortic elasticity in healthy postmenopausal women is unknown. The purpose of the present study was to examine the effect of raloxifene on aortic elasticity and cardiovascular structure and function in healthy postmenopausal women. METHODS:A randomized, crossover, double-blind, pl...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2005.02.020

    authors: Tritos NA,Goepfert L,Kissinger KV,Katsimaglis G,Manning WJ,Danias PG

    更新日期:2005-12-01 00:00:00

  • Reduced parasympathetic cardiac control in patients with hypertension at rest and under mental stress.

    abstract::The neurogenic component in the pathogenesis of essential hypertension has predominantly been analyzed with regard to the sympathetic part of the autonomous nervous system; the parasympathetic branch has largely been neglected. We investigated whether 54 normotensive (mean causal blood pressure [cBP]: 125 +/- 6/82 +/-...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(94)90517-7

    authors: Langewitz W,Rüddel H,Schächinger H

    更新日期:1994-01-01 00:00:00

  • Use and long-term outcomes of implantable cardioverter-defibrillators, 1990 to 2009.

    abstract:BACKGROUND:Automated implantable cardioverter-defibrillators (ICDs) have become standard therapy for patients at high risk for sudden cardiac death. Linked data allow examination of trends in use and long-term survival after ICD implantation in an adult population. METHODS:Linked state-wide person-based data on hospit...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2013.02.007

    authors: Bradshaw PJ,Stobie P,Briffa T,Hobbs MS

    更新日期:2013-05-01 00:00:00

  • The safety and efficacy of full- versus reduced-dose betrixaban in the Acute Medically Ill VTE (Venous Thromboembolism) Prevention With Extended-Duration Betrixaban (APEX) trial.

    abstract:BACKGROUND:The APEX trial assessed the safety and efficacy of extended-duration thromboprophylaxis using betrixaban versus standard dosing of enoxaparin among hospitalized, acutely ill medical patients. The 80-mg betrixaban dose was halved to 40 mg among subjects with severe renal insufficiency and those receiving a co...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2016.12.004

    authors: Gibson CM,Halaby R,Korjian S,Daaboul Y,Arbetter DF,Yee MK,Goldhaber SZ,Hull R,Hernandez AF,Lu SP,Bandman O,Leeds JM,Gold A,Harrington RA,Cohen AT,APEX Investigators.

    更新日期:2017-03-01 00:00:00

  • Newer antiarrhythmic drugs in children.

    abstract::Our experience with the use of five new antiarrhythmic drugs for treating life-threatening arrhythmias in children will be briefly reviewed. Prevention of recurrent episodes of atrial flutter with digoxin and local anesthetic antiarrhythmic drugs often is only moderately successful, benefiting 65% of patients. Amiodar...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(87)90027-5

    authors: Moak JP,Smith RT,Garson A Jr

    更新日期:1987-01-01 00:00:00

  • The acute effects of flecainide in the swine heart failing from incessant supraventricular tachycardia.

    abstract::The acute hemodynamic and electrophysiologic effects of flecainide in tachycardia-induced ventricular dysfunction were investigated using an animal model. Seven swine were initially (CON) evaluated by echocardiography and then by right heart catheterization and provocative electrical ventricular stimulation both befor...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(91)90018-d

    authors: Trippel DL,Harold ME,Spinale FG,Buckles DS,Gillette PC

    更新日期:1991-06-01 00:00:00

  • Resting cardiac energy metabolism is inversely associated with heart rate in healthy young adult men.

    abstract:BACKGROUND:31-Phosphorus-magnetic resonance spectroscopy may provide pathophysiological insights into the high-energy phosphate metabolism of the myocardium as measured by phosphocreatine to adenosine triphosphate (PCr/ATP) ratio. Aim of the present study was to determine in vivo the relation between cardiac PCr/ATP ra...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2011.04.012

    authors: Fragasso G,De Cobelli F,Spoladore R,Esposito A,Salerno A,Calori G,Montanaro C,Maranta F,Lattuada G,Margonato A,Del Maschio A,Perseghin G

    更新日期:2011-07-01 00:00:00

  • How to use ACE-inhibitors, beta-blockers, and newer therapies in AMI.

    abstract::Besides reperfusion treatment, which is the most powerful approach to the underlying pathophysiological cause of myocardial infarction, adjunctive therapies should be considered to reduce clinical symptoms, and improve left ventricular function and mortality rates. Randomized clinical trials and overviews of adjunctiv...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/s0002-8703(99)70341-8

    authors: Maggioni AP,Latini R

    更新日期:1999-08-01 00:00:00

  • Assessment of side branch predilation before a provisional T-stent strategy for bifurcation lesions. A randomized trial.

    abstract:BACKGROUND:A simple approach is the predominant strategy for the percutaneous coronary intervention of bifurcation lesions. Performing side branch (SB) predilation in this context is currently a matter of controversy. In this study, we assess the efficacy of SB predilatation before a provisional T-stent strategy for bi...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2014.05.014

    authors: Pan M,Medina A,Romero M,Ojeda S,Martin P,Suarez de Lezo J,Segura J,Mazuelos F,Novoa J,Suarez de Lezo J

    更新日期:2014-09-01 00:00:00

  • Pharmacologic characteristics of a new calcium antagonist, manidipine: beneficial effects on renal circulation and vascular changes.

    abstract::The calcium antagonist, manidipine, was developed on the basis of the hypothesis that antihypertensive drugs that act to improve renal hemodynamic alterations will be therapeutically beneficial in hypertensive patients. Manidipine shows long-lasting calcium channel-blocking action in vascular smooth muscle cells and a...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/0002-8703(93)90203-l

    authors: Nagaoka A

    更新日期:1993-02-01 00:00:00

  • Is long-term pharmacist-managed anticoagulation service efficient? A pragmatic randomized controlled trial.

    abstract:BACKGROUND:Some pharmacist-managed anticoagulation services (PMAS) provide initial follow-up to patients on oral anticoagulant, who are transferred to their physician once they are stabilized. This may be as effective as and less expensive than long-term PMAS follow-up. METHODS:Once PMAS patients were stabilized and r...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2008.02.009

    authors: Lalonde L,Martineau J,Blais N,Montigny M,Ginsberg J,Fournier M,Berbiche D,Vanier MC,Blais L,Perreault S,Rodrigues I

    更新日期:2008-07-01 00:00:00

  • Guidance of anticoagulation after intracoronary implantation of Palmaz-Schatz stents by monitoring prothrombin and prothrombin fragment 1 + 2.

    abstract::The primary objective of this study was to apply a sophisticated coagulation monitoring system including estimation of the concentration of prothrombin fragment 1 + 2 (PTF 1 + 2) and the activity of prothrombin (coagulation factor II or FII) to cases of stent implantation and to compare the results with those of stand...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-8703(95)90433-6

    authors: Haude M,Hafner G,Jablonka A,Rupprecht HJ,Prellwitz W,Meyer J,Erbel R

    更新日期:1995-08-01 00:00:00

  • An angiographic assessment of alteplase: double-bolus and front-loaded infusion regimens in myocardial infarction. DouBLE Study Investigators. Double Bolus Lysis Efficacy.

    abstract:BACKGROUND:This study was designed to investigate the efficacy of alteplase double-bolus dosing compared with the front-loaded 90-minute infusion regimen in patients with acute myocardial infarction. Recent pilot studies have suggested that bolus dosing may provide improved efficacy in establishing early, complete, and...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0002-8703(98)70024-9

    authors: Bleich SD,Adgey AA,McMechan SR,Love TW

    更新日期:1998-10-01 00:00:00

  • Cost-effectiveness perspectives in coronary heart disease.

    abstract::In the United States there has been a dramatic decrease in age-adjusted coronary heart disease (CHD) mortality during the last 20 years. This article investigates the reasons for this decline and concludes that most of the decline in CHD has been the result of life-style changes, particularly reduction in serum choles...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/s0002-8703(05)80054-7

    authors: Goldman L

    更新日期:1990-03-01 00:00:00