Continuous monitoring of acute myocardial ischemia by the implantable cardioverter defibrillator.

abstract：BACKGROUND:The risk for reinfarctions and delays in reperfusion after streptokinase therapy may be caused by the antifibrinolytic effect of platelet-derived type 1 plasminogen activator inhibitor (PAI-1). This study aims to show the relation of pretreatment PAI-1 levels of patients with acute myocardial infarction trea...

journal_title：American heart journal

authors： Sinkovic A

更新日期：1998-09-01 00:00:00

abstract：:Antiarrhythmic drugs are often more effective in suppressing ventricular tachycardias than are background premature extrasystoles. The mechanism of action of these agents was examined by studies on the effects of lidocaine and quinidine on post-repolarization refractoriness of both basic and premature action potential...

journal_title：American heart journal

authors： Nakaya Y,Nii H,Nomura M,Fujino K,Mori H

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The pathogenesis of human coronary artery disease (CAD) is likely to require the transcription of many different genes. We report here the differential gene expression profiling of human CAD using copy DNA (cDNA)/nylon array hybridization techniques. METHODS AND RESULTS:Human coronary arteries...

journal_title：American heart journal

authors： Satterthwaite G,Francis SE,Suvarna K,Blakemore S,Ward C,Wallace D,Braddock M,Crossman D

更新日期：2005-09-01 00:00:00

abstract：:To investigate the influence of intrinsic limb vasodilator capacity on exercise performance, limb reactive hyperemic flows and their relations to exercise capacity during upright bicycle exercise were examined in 52 patients with recent myocardial infarction. Reactive hyperemic flow was measured in the forearm and the...

journal_title：American heart journal

authors： Hattori T,Sumimoto T,Yuasa F,Kaida M,Jikuhara T,Hikosaka M,Sugiura T,Iwasaka T

更新日期：1996-09-01 00:00:00

abstract：:The purpose of this study was to determine whether myocardium salvaged by reperfusion following coronary occlusion could respond to inotropic stimulation by dopamine. Mongrel dogs underwent a 2-hour occlusion of the proximal left anterior descending coronary artery, followed by reperfusion for 5 or 28 hours. Dopamine ...

journal_title：American heart journal

authors： Ellis SG,Wynne J,Braunwald E,Henschke CI,Sandor T,Kloner RA

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:High mortality rates were reported in ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary interventions (PPCI) "off-hours." The objective of this study was to evaluate this issue in a more recent population of patients with STEMI treated with PPCI in a high-volume ter...

journal_title：American heart journal

authors： Ortolani P,Marzocchi A,Marrozzini C,Palmerini T,Saia F,Aquilina M,Baldazzi F,Silenzi S,Taglieri N,Grosseto D,Bacchi-Reggiani ML,Guastaroba P,Grilli R,Branzi A

更新日期：2007-08-01 00:00:00

abstract：:Clinical and necropsy findings are described in eight patients who lived 20 to 31 years (mean 24 years) after healing of a transmural acute myocardial infarct. Two had left ventricular aneurysms and one had both right and left ventricular infarcts. Survival for 2 decades or more after healing of a transmural acute myo...

journal_title：American heart journal

authors： McManus BM,Roberts WC

更新日期：1981-08-01 00:00:00

abstract：OBJECTIVE:To examine the safety and efficacy of cangrelor in patients with single-vessel disease (SVD) and multi-vessel disease (MVD). BACKGROUND:Cangrelor, an intravenous, rapidly acting P2Y12 inhibitor, is superior to clopidogrel in reducing ischemic events among patients receiving percutaneous coronary intervention...

journal_title：American heart journal

authors： Abnousi F,Sundaram V,Yong CM,Prats J,Deliargyris EN,Stone GW,Hamm CW,Steg PG,Gibson CM,White HD,Price MJ,Généreux P,Desai M,Yang L,Ding VY,Harrington RA,Bhatt DL,Mahaffey KW

更新日期：2017-06-01 00:00:00

abstract：:Epinephrine increases coronary blood flow but may not improve the balance between myocardial oxygen supply and demand during cardiopulmonary resuscitation (CPR). The objective of this study was to determine whether this balance can be improved by administering a relatively pure alpha-adrenergic vasoconstrictor, alone ...

journal_title：American heart journal

authors： Ditchey RV,Slinker BK

更新日期：1994-02-01 00:00:00

abstract：:The effects of captopril (CPT), an oral angiotensin-converting enzyme (ACE) inhibitor, on systemic failure (CHF). In 15 patients, CPT decreased mean arterial pressure from 75 +/- 3 to 60 +/- 3 mm Hg associated with a 16% increase in cardiac output, a 24% reduction in systemic vascular resistance, and a 36% decrease in...

journal_title：American heart journal

authors： Powers ER,Bannerman KS,Stone J,Reison DS,Escala EL,Kalischer A,Weiss MB,Sciacca RR,Cannon PJ

更新日期：1982-11-01 00:00:00

abstract：:Our purpose was to determine the incidence of mitral valve prolapse in patients with anxiety neurosis or panic disorder, with symptoms including recurrent anxiety attacks, dyspnea, palpitations, chest pain, dizziness, and paresthesias. Twenty-one patients and 20 age- and sex-matched normal controls were studied. Objec...

journal_title：American heart journal

authors： Venkatesh A,Pauls DL,Crowe R,Noyes R Jr,Van Valkenburg C,Martins JB,Kerber RE

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:ST-elevation myocardial infarctions (STEMI) caused by proximal left-anterior descending (LAD) lesions have more myocardium at risk and worse outcomes than those located in other segments. The aim is to compare outcomes of patients with STEMI and proximal-LAD lesions treated with bare-metal stents (BMS) versu...

journal_title：American heart journal

authors： Gomez-Lara J,Brugaletta S,Gomez-Hospital JA,Ferreiro JL,Roura G,Romaguera R,Martin-Yuste V,Masotti M,Iñiguez A,Serra A,Hernandez-Antolin R,Mainar V,Valgimigli M,Tespili M,den Heijer P,Bethencourt A,Vazquez N,Serruys P,

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Strenuous exercise can be a major trigger for coronary thrombosis and it enhances platelet aggregation. METHODS:We evaluated the effect of antiplatelet therapy on shear stress-induced platelet aggregation (SIPA), in addition to agonist-induced aggregation, before and immediately after ergometer exercise in ...

journal_title：American heart journal

authors： Kitai T,Nishikawa M,Tanigawa T,Okinaka T,Wada H,Shiku H,Ikeda Y,Ito M,Isaka N,Nakano T

更新日期：2001-08-01 00:00:00

abstract：:We studied the diagnostic value of exercise electrocardiographic (ECG) testing in 191 patients who were completely asymptomatic 6 months after a successful percutaneous transluminal coronary angioplasty procedure. With > 70%- and > 50%-diameter stenosis at follow-up as restenosis criteria, the sensitivities of exercis...

journal_title：American heart journal

authors： Desmet W,De Scheerder I,Piessens J

更新日期：1995-03-01 00:00:00

abstract：:Despite the well-proven benefits of cardiac rehabilitation and exercise training, no data are available on the benefits of this therapy in patients with preserved baseline exercise capacity. Therefore we assessed data before and after phase II cardiac rehabilitation and exercise programs at two large teaching institut...

journal_title：American heart journal

authors： Lavie CJ,Milani RV

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Previous studies have generated inconsistent results when attempting to define predictors of stroke and death in patients with endocarditis. We sought to examine the relationship between vegetation 2-dimensional size and stroke in those with infective endocarditis (IE) and to identify differences between aor...

journal_title：American heart journal

authors： Cabell CH,Pond KK,Peterson GE,Durack DT,Corey GR,Anderson DJ,Ryan T,Lukes AS,Sexton DJ

更新日期：2001-07-01 00:00:00

abstract：:The expected implant lifetime of pacemaker generators has been extended with the introduction of lithium power sources. Consequently, the pacing lead may become the component that determines the total implant lifetime of the pacemaker. This fact emphasizes the necessity for accurate assessment of the integrity of a ch...

journal_title：American heart journal

authors： Angello DA,McAnulty JH,Dobbs J

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Left atrial appendage flow velocity (LAAFV) is a predictor of thromboembolism in atrial fibrillation (AF) patients, as well as CHA2DS2-VASc score. However, little is known about LAAFV in sinus rhythm (SR) after catheter ablation. The aim of this study was to determine clinical predictors of low LAAFV in pati...

journal_title：American heart journal

authors： Kusa S,Komatsu Y,Taniguchi H,Uchiyama T,Takagi T,Nakamura H,Miyazaki S,Hachiya H,Iesaka Y

更新日期：2015-02-01 00:00:00

abstract：:This study was performed to assess the relation between the regional work and oxidative metabolism in hypertrophic cardiomyopathy (HCM). By using carbon 11 acetate as a tracer of myocardial blood flow (%A(0)) and oxygen consumption (k value), 12 patients with HCM with asymmetric septal hypertrophy and 10 normal subjec...

journal_title：American heart journal

authors： Ishiwata S,Maruno H,Senda M,Toyama H,Nishiyama S,Seki A

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Although there is evidence linking smoking and heart failure (HF), the association between lifetime smoking exposure and HF in older adults and the strength of this association among current and past smokers is not well known. METHODS:We examined the association between smoking status, pack-years of exposur...

journal_title：American heart journal

authors： Gopal DM,Kalogeropoulos AP,Georgiopoulou VV,Smith AL,Bauer DC,Newman AB,Kim L,Bibbins-Domingo K,Tindle H,Harris TB,Tang WW,Kritchevsky SB,Butler J

更新日期：2012-08-01 00:00:00

abstract：:Fifteen patients who arrived between 6 and 24 hours after the onset of acute myocardial infarction and who were found to have totally occluded coronary arteries, received aspirin, heparin, and tissue plasminogen activator given over 3 hours. Eight patients were randomly assigned to receive intravenous prostaglandin E1...

journal_title：American heart journal

authors： Kleiman NS,Tracy RP,Schaaff LJ,Harris S,Hill RD,Puleo P,Roberts R

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:The long-term fate of patent irradiated segments at 6 months after beta-radiation therapy has not been sufficiently evaluated. METHODS:Two-year follow-up angiography was performed in 52 patients with patent irradiated segments at 6 months after beta-radiation with a rhenium 188-mercaptoacetyltriglycine-fill...

journal_title：American heart journal

authors： Lee SW,Park SW,Hong MK,Kim YH,Han KH,Kim J,Park JH,Oh SJ,Moon DH,Oh SJ,Lee CW,Kim JJ,Park SJ

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Anemia in heart failure is both common and associated with worse symptoms and increased mortality. Several small randomized controlled trials (RCTs) have assessed erythropoiesis-stimulating agents (ESAs), but definitive evaluation and clinical guidance are required. We sought to systematically review the eff...

journal_title：American heart journal

authors： Kotecha D,Ngo K,Walters JA,Manzano L,Palazzuoli A,Flather MD

更新日期：2011-05-01 00:00:00

abstract：:Automatic external defibrillators (AEDs) represent an important technologic innovation in the management of out-of-hospital cardiac arrest. We propose the following concept: AEDs are machines with the limited task of ventricular fibrillation (VF) identification, countershock delivery, and defibrillation. They cannot b...

journal_title：American heart journal

authors： Cummins RO,Eisenberg MS,Hallstrom AP,Hearne TR,Graves JR,Litwin PE

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Pharmacodynamic studies reported an amplified on-clopidogrel platelet inhibition in smokers potentially caused by an increased metabolic drug activation via induction of cytochrome P450 1A2. The aims of this analysis were to evaluate the impact of smoking on the antiplatelet effect of clopidogrel and prasugr...

journal_title：American heart journal

authors： Hochholzer W,Trenk D,Mega JL,Morath T,Stratz C,Valina CM,O'Donoghue ML,Bernlochner I,Contant CF,Guo J,Sabatine MS,Schömig A,Neumann FJ,Kastrati A,Wiviott SD,Sibbing D

更新日期：2011-09-01 00:00:00

abstract：:To test alterations in plasma potassium and magnesium levels with maximal exercise, 15 sedentary, healthy men (mean age 29 years) participated in a double-blind crossover study for 11 weeks with propranolol, atenolol, and placebo. Maximal exercise tests were done at baseline and after placebo and beta-blockade phases....

journal_title：American heart journal

authors： Fletcher GF,Sweeney ME,Fletcher BJ

更新日期：1991-01-01 00:00:00

abstract：:Standard evaluation of children with sinus node (SN) dysfunction cannot distinguish abnormal autonomic tone from intrinsic SN disease. This distinction has potentially important therapeutic and prognostic implications. Intrinsic heart rate (IHR)--the peak heart rate (HR) measured during pharmacologic combined autonomi...

journal_title：American heart journal

authors： Marcus B,Gillette PC,Garson A Jr

更新日期：1990-04-01 00:00:00

abstract：:Angina pectoris before and after MI was evaluated in a sample of 729 men and women from a general population in whom MI developed during a 36-year period of follow-up. Relations of AP to subsequent CHD events and mortality after initial MI were analyzed by proportional hazards regression models and were adjusted for c...

journal_title：American heart journal

authors： Brand FN,Larson M,Friedman LM,Kannel WB,Castelli WP

更新日期：1996-07-01 00:00:00

abstract：:A double-blind multicenter study compared oral acebutolol (n = 182) with hydrochlorothiazide (n = 178) in the treatment of mild to moderate essential hypertension (diastolic blood pressure 95 to 114 mm Hg). Both agents produced significant and comparable reductions in systolic, diastolic, and mean arterial blood press...

journal_title：American heart journal

authors： Wahl J,Singh BN,Thoden WR

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Low heart rate recovery (HRR) at exercise test and the metabolic syndrome (MetS) are both predictors of cardiovascular morbidity and mortality. We studied in 75-year-old women and men, representative of the general population, the relationship between (1) HRR and the MetS, (2) HRR and the individual componen...

journal_title：American heart journal

authors： Nilsson G,Hedberg P,Jonason T,Lönnberg I,Ohrvik J

更新日期：2007-09-01 00:00:00