Abstract:
:Pantoea agglomerans has been transformed from a commensal bacterium associated with many plants into a host-specific gall-forming pathogen by acquiring a plasmid-borne pathogenicity island. This pathogenicity island harbors the hrp/hrc gene cluster, in addition to genes encoding type III effector proteins, biosynthesis of the phytohormones indole-3-acetic acid and cytokinin, multiple diverse insertion sequences and pseudogenes. This review describes a unique model for understanding the emergence of new pathogens or new pathogenic variants, offering an insight into the function of type III effectors in host specificity and the evolution of a pathogen into pathovars. It also addresses the primary role of type III effectors in gall initiation as compared with a secondary role of phytohormones secreted by the pathogen.
journal_name
Trends Microbioljournal_title
Trends in microbiologyauthors
Barash I,Manulis-Sasson Sdoi
10.1016/j.tim.2007.10.009subject
Has Abstractpub_date
2007-12-01 00:00:00pages
538-45issue
12eissn
0966-842Xissn
1878-4380pii
S0966-842X(07)00202-8journal_volume
15pub_type
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