Abstract：
:In 2004, we conducted a study in Piemonte (Italy), in order to describe incidence, treatment, hospitalizations and costs of herpes zoster (HZ), in population over 14 years of age. Twenty-four regional general practitioners, with 26,394 patients >14 years in charge (0.71% of the regional population), reported prospectively all diagnosed HZ cases. In addition, all regional hospital discharge records were reviewed. Forty-six HZ cases treated at home were reported, accounting for a total incidence of 1.74 cases/1000 population >14 years per year. HZ rate standardized by age on regional population 14 years older is 1.59/1000. The cost per observed home case was 136.06 euros. The incidence of hospital admissions was 0.12/1000 inhabitants. The mean cost of hospitalized cases was 4082.59 euros. These results contribute to depict the impact of HZ in the general population, and to provide background data for setting-up either mathematical models aimed to estimate the impact of vaccination on HZ, and the cost-benefit analyses of various preventive and therapeutic scenarios.
journal_name
Vaccinejournal_title
Vaccineauthors
Di Legami V,Gianino MM,Ciofi degli Atti M,Massari M,Migliardi A,Tomba GS,Zotti C,Zoster Study Group.doi
10.1016/j.vaccine.2007.07.049subject
Has Abstractpub_date
2007-10-23 00:00:00pages
7598-604issue
43eissn
0264-410Xissn
1873-2518pii
S0264-410X(07)00884-5journal_volume
25pub_type
杂志文章相关文献
VACCINE文献大全abstract：BACKGROUND:China is the most populous country in the world, with an annual birth cohort of approximately 16 million, requiring an average of 500 million vaccine doses administered annually. In China, over 30 domestic and less than 10 overseas vaccine manufacturers supply over 60 licensed vaccine products, representing ...
journal_title：Vaccine
pub_type： 杂志文章,评审
doi：10.1016/j.vaccine.2012.11.051
更新日期：2013-01-11 00:00:00
abstract：:Intranasal (i.n.) vaccination of mice with three doses of 40 microg of rRV stimulated low anti-ricin ELISA and neutralizing antibody responses, which were only marginally protective against aerosol-delivered 5-10 LD(50) of ricin toxin. To enhance the protection, and to reduce the lung injury of vaccinated mice that su...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2007.01.036
更新日期：2007-04-20 00:00:00
abstract：:Protective mechanisms underlying the responses to mucosal vaccination are not yet clearly defined. Using the natural mouse pneumovirus pathogen, pneumonia virus of mice (PVM), we explore responses of wild type and interferon-gamma (IFNgamma) receptor gene-deleted mice to virulent challenge after mucosal vaccination wi...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2006.09.081
更新日期：2007-01-22 00:00:00
abstract：:We evaluated the prevalence and concentration of serum antibodies 18-24 months after primary inoculation with anthrax and botulinum vaccines, and assessed the reactogenicity and immunogenicity of a significantly delayed booster dose of these vaccines. Five hundred and eight male active-duty military personnel received...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(02)00058-0
更新日期：2002-05-15 00:00:00
abstract：:The authors examined the antibody responses of mice orally immunized with pneumococcal polysaccharide (type 23F) or a pneumococcal polysaccharide conjugated to the outer membrane protein complex of Neisseria meningitides (23F-OMPC). These antigens were administered either in solution or entrapped within microcapsules....
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(98)00118-2
更新日期：1999-01-01 00:00:00
abstract：INTRODUCTION:In 2009, girls-only HPV16/18 vaccination was introduced in the Netherlands which has achieved 46-61% uptake. Heterosexual men have benefitted from herd protection, but it is unknown whether men who have sex with men (MSM) also benefit from herd effects of the girls-only HPV16/18 vaccination program. Becaus...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2020.03.002
更新日期：2020-04-09 00:00:00
abstract：:The immunity levels against diphtheria, tetanus and poliomyelitis were investigated among blood donors (n = 2079) in Berlin. Of all participants, only 60% had full, long-term protection against diphtheria, 72% against tetanus, 87% against poliomyelitis type 1, 77% against poliomyelitis type 2 and 73% against type 3. T...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(98)00269-2
更新日期：1999-02-26 00:00:00
abstract：:Immunization of hairless mice with a TK-, ACVr, non-pathogenic herpes simplex virus (HSV) type 1 mutant protected the mice against reinfection with lethal doses of the parental pathogenic HSV strain. The protection conferred by the mutant against the establishment of latency after reinfection with the parental strain ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/0264-410x(84)90089-6
更新日期：1984-09-01 00:00:00
abstract：:Human metapneumovirus (HMPV) is an important cause of acute respiratory tract disease for which the development of vaccine candidates is warranted. We have previously described the generation of an iscom matrix-adjuvanted HMPV fusion protein subunit vaccine (Fsol) and a live-attenuated vaccine (HMPVM11). Here, we eval...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2008.05.052
更新日期：2008-08-05 00:00:00
abstract：:Experimental whole-parasite immunization through concurrent administration of infectious Plasmodium sporozoites with drugs that prevent pathogenic blood-stage infection represents the current benchmark in malaria vaccine development. Key questions concerning translation remain, including the requirement for single-dos...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2014.07.112
更新日期：2014-10-14 00:00:00
abstract：:We report on the conduct of a systematic review to assess the efficacy and the safety of hepatitis A vaccines in adults and children. We identified, retrieved, and assessed all trials evaluating the effects of hepatitis A vaccines on prevention of cases of hepatitis A, death from hepatitis A, and assessing nature and ...
journal_title：Vaccine
pub_type： 杂志文章,评审
doi：10.1016/s0264-410x(03)00135-x
更新日期：2003-06-02 00:00:00
abstract：:In the present study we assessed the capacity of recombinant E. coli- or plasmid-expressed chicken interferons (IFN) and chicken IL-1beta, to exert immunostimulatory activities for humoral immune responses, in day-old and adult chickens. We observed that both recombinant E. coli-expressed chicken IFN-alpha/beta and IF...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(99)00537-x
更新日期：2000-04-14 00:00:00
abstract：:Organised and quality assured cytology-based screening programmes have substantially reduced cervical cancer incidence in many developed countries. However, there are considerable barriers to setting up cytology-based screening programs, particularly in developing countries. This has stimulated the search for novel an...
journal_title：Vaccine
pub_type： 杂志文章,评审
doi：10.1016/j.vaccine.2006.05.121
更新日期：2006-08-31 00:00:00
abstract：:In an effort to develop a safe and effective vaccine for the prevention of enterotoxigenic Escherichia coli (ETEC) K99 infections, we have developed a surface antigen display system using pgsA (poly-gamma-glutamate synthetase A) as an anchoring matrix. The recombinant fusion proteins comprised of pgsA and fimbriae pro...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.05.088
更新日期：2010-05-28 00:00:00
abstract：:Measles vaccination programmes at two vaccination centres in Ibadan, Nigeria were evaluated using the following factors as indicators: type of vaccination centre, age at vaccination, titre of vaccine, economic, health and social status of vaccinee. There was a significant association between type of vaccination centre...
journal_title：Vaccine
pub_type： 临床试验,杂志文章
doi：10.1016/0264-410x(92)90419-k
更新日期：1992-01-01 00:00:00
abstract：:Recombinant hepatitis B vaccine has been used widely in the world since 1991. The side effects of hepatitis B vaccine are seen rarely. In this paper, we present clinical and laboratory progress of an infant who gets severe thrombocytopenia after the second dosage hepatitis B vaccine. Our case is different from other c...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2008.09.062
更新日期：2008-12-02 00:00:00
abstract：:Japanese encephalitis (JE) vaccine has been used in childhood immunization programmes in Asia for many years. Also travellers from other parts of the world have been vaccinated before travelling in Asian countries. Recommendations for the use of JE vaccine are still debated because severe cases of adverse reactions ha...
journal_title：Vaccine
pub_type： 临床试验,杂志文章
doi：10.1016/s0264-410x(97)00020-0
更新日期：1997-08-01 00:00:00
abstract：:Increases in global travel, trade and urbanisation are leading to greater incidence of zoonotic disease, and livestock are often a key link in the spread of disease to humans. As such, livestock vaccination strategies, as a part of broader biosecurity solutions, are critical to both animal and human health. Importantl...
journal_title：Vaccine
pub_type： 杂志文章,评审
doi：10.1016/j.vaccine.2017.07.110
更新日期：2017-10-20 00:00:00
abstract：OBJECTIVES:We aimed to estimate vaccine effectiveness against severe measles based on the number of vaccine doses administered and the time since last vaccination. PATIENTS AND METHODS:We included measles cases aged at least 2 years and born since 1980 who were notified in France between 2006 and mid-2019. We consider...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2020.05.005
更新日期：2020-06-15 00:00:00
abstract：:The inflexibility of existing serological techniques for detection of rabies in surveillance constrains the benefit to be gained from many current control strategies. We analysed 304 serum samples from Tanzanian dogs for the detection of rabies antibodies in a pseudotype assay using lentiviral vectors bearing the CVS-...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.09.024
更新日期：2009-11-27 00:00:00
abstract：:The development of live attenuated vaccines, allowing for the safe and effective immunisation at mucosal surfaces, is a strategy of great interest for vaccinologists. The main advantage of this approach over conventional parenteral vaccines is the induction of strong mucosal immune responses, allowing targeting of the...
journal_title：Vaccine
pub_type： 杂志文章,评审
doi：10.1016/j.vaccine.2003.12.033
更新日期：2004-06-23 00:00:00
abstract：:In case of an influenza pandemic, the world will be in a situation where potential vaccine supply will fall short by several billion doses from global needs. The World Health Organization (WHO) convened in Geneva on May 2-3, 2006 a consultation of all stakeholders in influenza vaccines and immunization to identify pra...
journal_title：Vaccine
pub_type：
doi：10.1016/j.vaccine.2006.07.021
更新日期：2006-09-29 00:00:00
abstract：:Some technological and immunological problems facing the preparation of subunit viral vaccines are discussed. Solubilization of enveloped virus glycoproteins with various detergents has been studied. It has been demonstrated that a novel non-ionic detergent, MESK, can be used to prepare the glycoproteins of enveloped ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/0264-410x(88)90148-x
更新日期：1988-10-01 00:00:00
abstract：:This study was designed to evaluate the immunogenicity of autoclaved and nonautoclaved preparations of a vaccine composed of whole antigens from killed promastigotes of Leishmania amazonensis. Leishmanin skin-test (LST)-negative volunteers were immunized with either autoclaved or nonautoclaved vaccine preparations (32...
journal_title：Vaccine
pub_type： 临床试验,杂志文章
doi：10.1016/s0264-410x(98)00338-7
更新日期：1999-03-05 00:00:00
abstract：:DNA isolates from a number of established cell lines have been tested for their transforming capacity in the NIH3T3 transformation assay. It has been found that this assay can be used to quantify the amount of transforming DNA at a submicrogram to milligram level. This assay system has been applied to validate the red...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/0264-410x(85)90126-4
更新日期：1985-12-01 00:00:00
abstract：:In presence of low or high levels of rotavirus-specific maternal antibodies, the ability of newborn mice to respond to immunization with rotavirus RF 8*-2/6/7 VLPs, was evaluated. After parenteral vaccination, 100% of offspring born to low-antibody-titer dams developed rotavirus-specific IgG antibodies (n=7). In contr...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2007.11.089
更新日期：2008-02-06 00:00:00
abstract：:In this study we have investigated the immunogenicity and antigenicity of synthetic immunocontraceptive vaccine candidates containing T- and B-cell epitopes arranged in different geometries. Two epitopes were selected, a B-cell epitope from fox sperm lactate dehydrogenase C(4) and a B-cell epitope from murine zona pel...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(99)00255-8
更新日期：1999-10-14 00:00:00
abstract：:Helicobacter pylori neutrophil-activating protein (NAP) is a toll-like receptor 2 (TLR2) agonist and potent immunomodulator inducing Th1-type immune response. Here we present data about characterization of the humoral immune response against NAP-tagged antigens, encoded by attenuated measles virus (MV) vector platform...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2013.07.085
更新日期：2013-10-01 00:00:00
abstract：:DNA vaccination is particularly efficient for induction of cytotoxic T-lymphocyte (CTL) response. In our experiments, we used MHC(B) congenic chicken lines CB and CC (regressors and progressors of v-src-induced tumours, respectively) and a mutated, non-oncogenic v-src gene construct as the DNA vaccine. A high degree o...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(01)00181-5
更新日期：2001-08-14 00:00:00
abstract：:Two rotavirus vaccines have been available since 2006. This study evaluates the effectiveness of these vaccines using a test-negative case-control design in Navarre, Spain. We included children 3-59 months of age who sought medical care for gastroenteritis and for whom stool samples were taken between January 2008 and...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2011.11.071
更新日期：2012-01-11 00:00:00
