Seroprevalence and determinants of diphtheria, tetanus and poliomyelitis antibodies among adults in Berlin, Germany.

Abstract:

:The immunity levels against diphtheria, tetanus and poliomyelitis were investigated among blood donors (n = 2079) in Berlin. Of all participants, only 60% had full, long-term protection against diphtheria, 72% against tetanus, 87% against poliomyelitis type 1, 77% against poliomyelitis type 2 and 73% against type 3. There was a striking decrease of tetanus and diphtheria immunity levels by age. Immunity levels against tetanus were higher among males, whereas females were better protected against poliomyelitis. After adjusting for confounding effects in logistic regression diphtheria immunity in those aged <40 years was significantly higher in participants from East-Berlin, whereas the immunity levels against poliomyelitis were higher in West-Berlin. These differences reflect the different vaccination policies in East-Germany and West-Germany before 1989. There is a need to improve the immunity levels of the adult population in Berlin.

journal_name

Vaccine

journal_title

Vaccine

authors

Stark K,Schönfeld C,Barg J,Molz B,Vornwald A,Bienzle U

doi

10.1016/s0264-410x(98)00269-2

subject

Has Abstract

pub_date

1999-02-26 00:00:00

pages

844-50

issue

7-8

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(98)00269-2

journal_volume

17

pub_type

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