Clinical types of HBsAg-positive hepatitis.

abstract：:A devastating disease spread by mosquitoes with high-efficiency, malaria imposes an enormous burden for which no licensed vaccine currently exists. Although the genome complexity of the parasite has made vaccine development tenuous, an effective malaria vaccine would be a valuable tool for control, elimination and eve...

journal_title：Vaccine

authors： Palacpac NM,Arisue N,Tougan T,Ishii KJ,Horii T

更新日期：2011-08-11 00:00:00

abstract：:Carcinoembryonic antigen (CEA), which is expressed in several cancer types, is a potential target for specific immunotherapy. In this study, the feasibility of using dendrite cells (DCs) for tumor immunotherapy after transduction with a recombinant adenovirus containing CEA gene (AdVCEA) was investigated. The recombin...

journal_title：Vaccine

authors： Cho HI,Kim HJ,Oh ST,Kim TG

更新日期：2003-12-12 00:00:00

abstract：:The first population-based survey to determine predictors of influenza vaccination among children in a major metropolitan city with access to publicly funded health care and a universal influenza immunization program (UIIP). Previously collected demographic and health related data from 5619 school children aged 5-9 in...

journal_title：Vaccine

authors： Foty RG,Guttmann A,Kwong JC,Maaten S,Manuel D,Stieb DM,Dell SD

更新日期：2010-09-07 00:00:00

abstract：:Measles vaccine is widely used, most often in association with mumps and rubella vaccines. We report here the case of a child presenting with fever 8 days after vaccination with a measles-mumps-rubella vaccine. Measles virus was isolated in a throat swab taken 4 days after fever onset. This virus was then further gene...

journal_title：Vaccine

authors： Morfin F,Beguin A,Lina B,Thouvenot D

更新日期：2002-02-22 00:00:00

abstract：:In a severe pandemic, rapid production and deployment of vaccines will potentially be critical in mitigating the impact on populations and essential services. We compared access to vaccines and timing of delivery relative to identification of A(H1N1)pdm09 and the geographic progression of the pandemic in the WHO Europ...

journal_title：Vaccine

authors： Jorgensen P,Wasley A,Mereckiene J,Cotter S,Weber JT,Brown CS

更新日期：2013-08-28 00:00:00

abstract：BACKGROUND:The present study evaluated immunogenicity and tolerance of two-dose influenza A/H1N1pdm09 vaccination in allogeneic hematopoietic stem cell transplantation (HSCT) recipients, and compared the vaccine-induced humoral response to that triggered by natural infection in another group of HSCT patients. METHODS:...

journal_title：Vaccine

authors： Dhédin N,Krivine A,Le Corre N,Mallet A,Lioure B,Bay JO,Rubio MT,Agape P,Thiébaut A,Le Goff J,Autran B,Ribaud P

更新日期：2014-01-23 00:00:00

abstract：:Vaccination is the principal means used to control and treat porcine reproductive and respiratory syndrome virus (PRRSV) infection. An array of PRRS vaccine products is available in various regions of the world. However, despite extensive efforts, little progress has been made to improve efficacy since the first intro...

journal_title：Vaccine

authors： Murtaugh MP,Genzow M

更新日期：2011-10-26 00:00:00

abstract：:Optimized DNA vectors were constructed comprising the proteome of SIV including the structural, enzymatic, regulatory, and accessory proteins. In addition to native antigens as produced by the virus, fusion proteins and modified antigens with altered secretion, cellular localization and stability characteristics were ...

journal_title：Vaccine

authors： Kulkarni V,Jalah R,Ganneru B,Bergamaschi C,Alicea C,von Gegerfelt A,Patel V,Zhang GM,Chowdhury B,Broderick KE,Sardesai NY,Valentin A,Rosati M,Felber BK,Pavlakis GN

更新日期：2011-09-09 00:00:00

abstract：:The development of potent adjuvants, conditioning innate and adaptative immunity, particularly CTL responses, has become currently a hot point in the rational design of vaccines for cancer immunotherapy. We have described a new approach, in which gangliosides are incorporated into vesicles from Neisseria meningitidis ...

journal_title：Vaccine

authors： Mesa C,de León J,Fernández LE

更新日期：2006-03-24 00:00:00

abstract：:Currently, commercial porcine rotavirus vaccines remain varied limitations. The objective of this study is to develop an alternative porcine rotavirus subunit vaccine candidate by parenteral administration, which enables to elicit robust immune responses against most prevalence porcine rotavirus strains. The bacterial...

journal_title：Vaccine

authors： Wen X,Wei X,Ran X,Ni H,Cao S,Zhang Y

更新日期：2015-08-26 00:00:00

abstract：:The present study assessed the efficacy of Clostridium perfringens (C. perfringens) toxoid and/or allicin - as feed additive - in rabbits for preventing or minimizing the severity of infection with locally isolated strain of C. perfringens type A. Serum biochemical, immunological and pathological investigations were a...

journal_title：Vaccine

authors： Abu El Hammed W,Soufy H,El-Shemy A,Nasr SM,Dessouky MI

更新日期：2016-04-12 00:00:00

abstract：:In the present study, cross-protection to bovine herpesvirus type 5 (BHV-5) induced by bovine herpesvirus type 1 (BHV-1) vaccination was examined following inoculation of rabbits and calves with a glycoprotein E (gE)-negative BHV-1 vaccine and subsequent challenge with BHV-5. Rabbits (n=5) and calves (n=8) were vaccin...

journal_title：Vaccine

authors： Silva AD,Spilki FR,Franco AC,Esteves PA,Hübner SO,Driemeier D,Oliveira AP,Rijsewijk F,Roehe PM

更新日期：2006-04-12 00:00:00

abstract：:The ability to elicit humoral and cell-mediated immune (CMI) responses from DNA immunization by combinational use of codon optimization and C3d component of complement was evaluated in this study. DNA vaccines that express either the wild type or the codon optimized gp120 gene coding for the envelope (Env) glycoprotei...

journal_title：Vaccine

authors： Liu F,Mboudjeka I,Shen S,Chou TH,Wang S,Ross TM,Lu S

更新日期：2004-04-16 00:00:00

abstract：:The continued use of oral polio vaccine (OPV) poses a threat to polio virus eradication. Stopping all polio vaccination in the post-certification era is no longer considered to be a practical option. Policy makers agree that OPV use must stop immediately after certification. Therefore, the pragmatic alternative is for...

journal_title：Vaccine

authors： Khan MM

更新日期：2008-04-07 00:00:00

abstract：BACKGROUND:While childhood vaccines are safe and effective, some parents remain hesitant to vaccinate their children, which has led to outbreaks of vaccine preventable diseases. The goal of this systematic review was to identify and summarize the range of beliefs around childhood vaccines elicited using open-ended ques...

journal_title：Vaccine

authors： Gidengil C,Chen C,Parker AM,Nowak S,Matthews L

更新日期：2019-10-23 00:00:00

abstract：INTRODUCTION:Diarrhea is one of the leading causes of death in children under 5, and an estimated 39% of these deaths are attributable to rotavirus. Currently two live, oral rotavirus vaccines have been introduced on the market; however, the herd immunity effect associated with rotavirus vaccine has not yet been quanti...

journal_title：Vaccine

authors： Pollard SL,Malpica-Llanos T,Friberg IK,Fischer-Walker C,Ashraf S,Walker N

更新日期：2015-07-31 00:00:00

abstract：:T-lymphocyte responses to influenza vaccination were measured in healthy young and older adult volunteers. All participants were vaccinated with the 1995-96 trivalent influenza vaccine. Cytokine and granzyme B levels were measured in peripheral blood mononuclear cells (PBMC) cultures after virus stimulation, prior to ...

journal_title：Vaccine

authors： McElhaney JE,Upshaw CM,Hooton JW,Lechelt KE,Meneilly GS

更新日期：1998-11-01 00:00:00

abstract：:Vaccination of health-care workers (HCWs) against seasonal influenza has been consistently recommended worldwide in order to prevent nosocomial transmission and ensure delivery of health-care services during outbreaks. We describe the effects of a nationwide campaign to promote influenza vaccination among HCWs working...

journal_title：Vaccine

authors： Dedoukou X,Nikolopoulos G,Maragos A,Giannoulidou S,Maltezou HC

更新日期：2010-08-23 00:00:00

abstract：:Availability of vaccines may be temporarily affected by sudden peak demand, coming on top of the vast increases of regular demand that the world has witnessed; this must be addressed by sound planning, and flexibility both from manufacturers and users. Temporary shortages are not structural in nature, and capacity is ...

journal_title：Vaccine

authors： Vandersmissen W

更新日期：1992-01-01 00:00:00

abstract：:We developed a novel procedure to evoke anti-aggregating beta-amyloid (Abeta) antibodies, using filamentous phages displaying only four amino acids EFRH of the beta-amyloid peptide (AbetaP). This epitope was found to be the main regulatory site for fibril formation. For the first time, effective auto-antibodies have b...

journal_title：Vaccine

authors： Frenkel D,Kariv N,Solomon B

更新日期：2001-03-21 00:00:00

abstract：:Children in public care have poor health outcomes despite statutory health assessments. Incomplete immunisation of children entering the care system has been reported. Does this health disadvantage persist for those established in the care system? The immunisation status of 119 children in public care for at least 6 m...

journal_title：Vaccine

authors： Barnes P,Price L,Maddocks A,Cheung WY,Williams J,Jackson S,Mason B

更新日期：2005-04-15 00:00:00

abstract：:The antimetastatic effects of MDP-Lys(L18), a lipophilic derivative of muramyl dipeptide (MDP), against three different types of highly metastatic murine tumour cells, B16-BL6 melanoma, colon 26-M3.1 carcinoma and L5178Y-ML25 T lymphoma, were examined in C57BL/6, Balb/c and CDF1 mice, respectively. The administration ...

journal_title：Vaccine

authors： Yoo YC,Saiki I,Sato K,Azuma I

更新日期：1994-02-01 00:00:00

abstract：:We reviewed studies of rotavirus in MEDLINE and the Chinese literature to get a preliminary estimate of the burden of rotavirus gastroenteritis in China and the epidemiology of the disease. Studies were selected if they were conducted for a period 1 year or more, had more than 100 patients enrolled, and used an accept...

journal_title：Vaccine

authors： Orenstein EW,Fang ZY,Xu J,Liu C,Shen K,Qian Y,Jiang B,Kilgore PE,Glass RI

更新日期：2007-01-05 00:00:00

abstract：:Although the theoretical concern of genetic recombination has been raised related to the use of live attenuated flavivirus vaccines [Seligman, Gould, Lancet 2004;363:2073-5], it has little foundation [e.g., Monath TP, Kanesa-Thasan N, Guirakhoo F, Pugachev K, Almond J, Lang J, et al. Vaccine 2005;23:2956-8]. To invest...

journal_title：Vaccine

authors： Pugachev KV,Schwaiger J,Brown N,Zhang ZX,Catalan J,Mitchell FS,Ocran SW,Rumyantsev AA,Khromykh AA,Monath TP,Guirakhoo F

更新日期：2007-09-17 00:00:00

abstract：:Here, we evaluated the modulation of the immune response induced by Hsp90 of Nicotiana benthamiana (NbHsp90.3) against the Maltose Binding Protein (MBP) as a reporter antigen. Equimolar quantities of recombinant proteins were administered in mice as follows: MBP alone (MBP group), a mixture of MBP and rNbHsp90.3 (MBP+...

journal_title：Vaccine

authors： Corigliano MG,Fenoy I,Sander V,Maglioco A,Goldman A,Clemente M

更新日期：2013-12-02 00:00:00

abstract：:We show here that the immunogenicity of the Modified Vaccinia Ankara MVA vaccine strain can be improved by deletion of the A35 gene, without diminishing the ability of the virus to replicate. Deletion of the A35 gene resulted in increased virus-specific immunoglobulin production, class switching to IgG isotypes, and v...

journal_title：Vaccine

authors： Rehm KE,Roper RL

更新日期：2011-04-12 00:00:00

abstract：:Protein C deletion mutants of West Nile virus (WNV) were evaluated for their potential use as live virus vaccine candidates in vivo. Double and triple mutants carrying small deletions and second-site point mutations, as well as mutants with large deletions of 36 and 37 amino acid residues were tested in a stringent mo...

journal_title：Vaccine

authors： Schlick P,Kofler RM,Schittl B,Taucher C,Nagy E,Meinke A,Mandl CW

更新日期：2010-08-16 00:00:00

abstract：:Eight different vaccination schemes using four commercially available inactivated Bluetongue vaccines against serotypes 4 and 8 in three different combinations (setting 1-3) were tested under field conditions for their ability to generate a measurable immune response in sheep. Animals of setting 1 (groups A-D) were si...

journal_title：Vaccine

authors： Hilke J,Strobel H,Woelke S,Stoeter M,Voigt K,Grimm L,Meilwes J,Punsmann T,Blaha I,Salditt A,Rohn K,Bastian M,Ganter M

更新日期：2019-09-16 00:00:00

abstract：:A growing number of people use the Internet to obtain health information, including information about vaccines. Websites that allow and promote interaction among users are an increasingly popular source of health information. Users of such so-called Web 2.0 applications (e.g. social media), while still in the minority...

journal_title：Vaccine

authors： Betsch C,Brewer NT,Brocard P,Davies P,Gaissmaier W,Haase N,Leask J,Renkewitz F,Renner B,Reyna VF,Rossmann C,Sachse K,Schachinger A,Siegrist M,Stryk M

更新日期：2012-05-28 00:00:00

abstract：:During the years 2009 and 2010 relevant epidemic waves of foot-and-mouth disease (FMD) serotype O occurred in Ecuador, representing a great drawback for the last stages of the ongoing eradication program in South America. This study describes the molecular and antigenic characterizations of 29 isolates collected from ...

journal_title：Vaccine

authors： Maradei E,Perez Beascoechea C,Malirat V,Salgado G,Seki C,Pedemonte A,Bonastre P,D'Aloia R,La Torre JL,Mattion N,Rodríguez Toledo J,Bergmann IE

更新日期：2011-10-26 00:00:00