Characterization of foot-and-mouth disease virus from outbreaks in Ecuador during 2009-2010 and cross-protection studies with the vaccine strain in use in the region.

abstract：:It has been known that influenza A virus infection induces a cross-protective immunity against infection by viruses with different subtypes of viral envelope proteins, hemagglutinin (HA) and neuraminidase (NA). This heterosubtypic immunity is generally mediated by cytotoxic T lymphocytes (CTL) reactive to specific epi...

journal_title：Vaccine

authors： Takada A,Matsushita S,Ninomiya A,Kawaoka Y,Kida H

更新日期：2003-07-04 00:00:00

abstract：:Shigellosis, a major cause of diarrhea worldwide, exhibits high morbidity and mortality in children. Specificity of Shigella immunity is determined by the structure of the main protective O-antigen polysaccharide component incorporated into the lipopolysaccharide (LPS) molecule. Endotoxicity, however, precludes LPS cl...

journal_title：Vaccine

authors： Ledov VA,Golovina ME,Markina AA,Knirel YA,L'vov VL,Kovalchuk AL,Aparin PG

更新日期：2019-02-14 00:00:00

abstract：:The vaccination of wild animals against rabies has been developed most extensively in Europe. Experiments have demonstrated the efficacy of a vaccinia-rabies recombinant virus administered by the oral route in foxes. The innocuity of this vaccine was tested in the target species as well as in several non-target wild a...

journal_title：Vaccine

authors： Brochier B,Thomas I,Bauduin B,Leveau T,Pastoret PP,Languet B,Chappuis G,Desmettre P,Blancou J,Artois M

更新日期：1990-04-01 00:00:00

abstract：:TA-CIN is a vaccine that comprises the human papillomavirus (HPV) type 16 L2, E6 and E7 as a single fusion protein. In a mouse model, TA-CIN effectively prevented outgrowth of HPV16-positive tumour cells. To assess the safety and immunogenicity of TA-CIN, a dose escalating (26, 128, 533 micro g), double blind and plac...

journal_title：Vaccine

authors： de Jong A,O'Neill T,Khan AY,Kwappenberg KM,Chisholm SE,Whittle NR,Dobson JA,Jack LC,St Clair Roberts JA,Offringa R,van der Burg SH,Hickling JK

更新日期：2002-10-04 00:00:00

abstract：:Because of the serious economic and medical consequences of brucellosis, efforts are to prevent infection of domestic animals through vaccines. Many disadvantages are associated with the current Brucella melitensis Rev.1 vaccine prompting development of alternative vaccines and delivery. Escherichia coli (DH5α) was en...

journal_title：Vaccine

authors： Gupta VK,Radhakrishnan G,Harms J,Splitter G

更新日期：2012-06-08 00:00:00

abstract：:The principle of deliberately infecting humans with infectious agents in a controlled setting, so-called controlled human infections (CHI), is not novel. Many CHI models have a long history and were established decades ago such as the intentional exposure to yellow fever and dengue performed in the 1900's (Reed, 1902)...

journal_title：Vaccine

authors： Roestenberg M,Mo A,Kremsner PG,Yazdanbakhsh M

更新日期：2017-12-18 00:00:00

abstract：:Oral poliovirus vaccine (OPV) is tested for safety by evaluation of neurovirulence in rhesus and cynomolgus macaques. After intraspinal or intrathalamic injection of varying doses of vaccine, monkeys are followed for 17-21 days, killed, and a histopathological evaluation is made of the severity of poliomyelitis lesion...

journal_title：Vaccine

authors： Nathanson N,Horn SD

更新日期：1992-01-01 00:00:00

abstract：:Measles outbreaks occur periodically in remote and difficult to reach areas in countries such as the Democratic Republic of Congo. The possibility to keep measles vaccines at temperatures outside the cold chain for a limited period prior to administration would be an advantage for organizations such as Médecins Sans F...

journal_title：Vaccine

authors： Juan-Giner A,Alsalhani A,Panunzi I,Lambert V,Van Herp M,Gairola S

更新日期：2020-03-04 00:00:00

abstract：:The goal of the present study was to evaluate the influence of the influenza A H1N1/2009 vaccine on dermatomyositis/polymyositis (DM/PM) disease parameters and the potential deleterious effect of therapy on immune response. Thirty-seven DM and 21 PM patients (Bohan and Peter's criteria) were gender- and age-matched to...

journal_title：Vaccine

authors： Shinjo SK,de Moraes JC,Levy-Neto M,Aikawa NE,de Medeiros Ribeiro AC,Schahin Saad CG,Precioso A,Silva CA,Bonfá E

更新日期：2012-12-17 00:00:00

abstract：PURPOSE:We tested the hypotheses that consistency and strength of clinician recommendation of the human papillomavirus (HPV) vaccination would be associated with vaccine delivery rates. METHODS:From October 2015 through January 2016, we conducted a survey of primary care clinicians (n=227) in Southeastern Minnesota to...

journal_title：Vaccine

authors： Finney Rutten LJ,St Sauver JL,Beebe TJ,Wilson PM,Jacobson DJ,Fan C,Breitkopf CR,Vadaparampil ST,MacLaughlin KL,Jacobson RM

更新日期：2017-10-27 00:00:00

abstract：:Fasciolosis continues to be a major cause of economic losses in the livestock industry and a growing threat to humans. The limited spectrum of effective anthelmintics and the appearance of resistances urge the need for developing an effective vaccine. Most studies have been focused on the use of TH1-polarizing adjuvan...

journal_title：Vaccine

authors： Orbegozo-Medina RA,Martínez-Sernández V,González-Warleta M,Castro-Hermida JA,Mezo M,Ubeira FM

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is a pathogen which causes life-threatening infection, the incidence of which rises during adult life. This, together with the emergence of drug-resistant strains and the expansion of more susceptible elderly populations, represents the rationale for the ongoing development of S. aureus...

journal_title：Vaccine

authors： Whitehouse J,Flaxman A,Rollier C,O'Shea MK,Fallowfield J,Lindsay M,Gunner F,Knox K,Wyllie DH,Yamaguchi Y

更新日期：2016-04-04 00:00:00

abstract：:Two shots of inactivated Japanese encephalitis (JE) vaccine were given to children, 139 with underlying diseases and 42 healthy, and their antibody responses were studied by the neutralization test. Before vaccination, most of the vaccinees did not have antibody against JE virus. One month after the second vaccination...

journal_title：Vaccine

authors： Yamada A,Imanishi J,Juang RF,Fukunaga T,Okuno Y,Tadano M,Fukai K,Baba K,Yabuuchi H

更新日期：1986-03-01 00:00:00

abstract：:In some serotypes of adenovirus (Ad), the penton base and attached trimeric fiber assemble into dodecameric virus-like particles called penton-dodecahedron (Pt-Dd), which can be internalized and used to deliver the vaccine antigens and drugs. Fowl adenovirus serotype 4 (FAdV-4) is an important pathogen, causing seriou...

journal_title：Vaccine

authors： Wang X,Tang Q,Qiu L,Yang Z

更新日期：2019-02-04 00:00:00

abstract：PURPOSE:Vaccines recommended for adolescents are considered safe and effective, however administration may occasionally result in acute pain at the injection site or syncope (fainting). These adverse effects pose a risk to patient safety and are potential barriers to adherence to future vaccinations. We assessed a nove...

journal_title：Vaccine

authors： Henninger ML,Kuntz JL,Firemark AJ,Varga AM,Bok K,Naleway AL

更新日期：2018-06-22 00:00:00

abstract：:A live Salmonella Enteritidis vaccine (SE147N ΔphoP fliC), able to express both a homologous intestinal colonisation-inhibition effect and a systemic invasion-inhibition effect, was tested for its potential to generate a postulated additive protective effect in case of combined application with a competitive exclusion...

journal_title：Vaccine

authors： Methner U,Berndt A,Locke M

更新日期：2017-10-27 00:00:00

abstract：:Vaccination of poultry against coccidiosis caused by the Eimeria species is almost entirely based upon varied formulations of live parasites. The recent development of a series of protocols that support genetic complementation by transfection in Eimeria now provides an opportunity to utilise live anticoccidial vaccine...

journal_title：Vaccine

authors： Clark JD,Oakes RD,Redhead K,Crouch CF,Francis MJ,Tomley FM,Blake DP

更新日期：2012-03-30 00:00:00

abstract：:In anticipation of the implementation of new prophylactic HPV vaccines, the WHO is supporting the establishment of a global WHO HPV Laboratory Network whose mission is to "contribute to improving the quality of laboratory services for effective surveillance and monitoring of HPV vaccination impact through enhanced, st...

journal_title：Vaccine

authors： Ferguson M,Wilkinson DE,Zhou T

更新日期：2009-01-14 00:00:00

abstract：:A reverse transcriptase polymerase chain reaction (PCR) was used to amplify a 235 bp hypervariable region of the feline calicivirus (FCV) genome which encodes part of the capsid protein. Sequence from this region was used to compare viruses used in three attenuated vaccines to viruses isolated from vaccinated cats wit...

journal_title：Vaccine

authors： Radford AD,Bennett M,McArdle F,Dawson S,Turner PC,Glenn MA,Gaskell RM

更新日期：1997-08-01 00:00:00

abstract：:We assessed the tetanus immunity of the general Dutch population and of religious groups refusing vaccination by means of population-based study to evaluate the effect of tetanus vaccination. More than 95% of those born after the introduction of routine vaccination had tetanus antitoxin levels above the minimum protec...

journal_title：Vaccine

authors： de Melker HE,van den Hof S,Berbers GA,Nagelkerke NJ,Rümke HC,Conyn-van Spaendonck MA

更新日期：1999-08-20 00:00:00

abstract：:Despite the availability of anti-microbial agents effective against Neisseria meningitidis, meningococcal disease continues to be a major global health problem, particularly in the very young. Serogroup A meningococci cause large epidemics in sub-Saharan Africa, whilst serogroups B and C organisms are responsible for ...

journal_title：Vaccine

authors： Borrow R,Balmer P,Miller E

更新日期：2005-03-18 00:00:00

abstract：BACKGROUND:Liposome encapsulated neutralizing epitope protein of Hepatitis E virus (HEV), rNEp, our Hepatitis E vaccine candidate, was shown to be immunogenic and safe in pregnant and non-pregnant mice and yielded sterilizing immunity in rhesus monkeys. METHODS:The current study in Balb/c mice assessed the levels and ...

journal_title：Vaccine

authors： Kulkarni SP,Thanapati S,Arankalle VA,Tripathy AS

更新日期：2016-11-21 00:00:00

abstract：:Hepatitis B virus (HBV) infection and HBV-associated diseases are prevalent in many parts of the Middle East and North Africa. Postnatal horizontal childhood transmission appears to be the predominant method by which high hepatitis B carrier rates are maintained. To control hepatitis B in this region, mass immunizatio...

journal_title：Vaccine

authors： Toukan A

更新日期：1990-03-01 00:00:00

abstract：:Rotavirus vaccine was introduced in El Salvador in 2006 and is recommended to be given concomitantly with DTP-HepB-Haemophilus influenzae type b (pentavalent) vaccine at ages 2 months (upper age limit 15 weeks) and 4 months (upper age limit 8 months) of age. However, rotavirus vaccination coverage continues to lag beh...

journal_title：Vaccine

authors： Suarez-Castaneda E,Burnett E,Elas M,Baltrons R,Pezzoli L,Flannery B,Kleinbaum D,de Oliveira LH,Danovaro-Holliday MC

更新日期：2015-11-27 00:00:00

abstract：:Using HIV-1 envelope protein (Env)-based immunogens that closely mimic the conformation of functional HIV-1 Envs and represent the isolates prevalent in relevant geographical region is considered a rational approach towards developing HIV vaccine. We recently reported that like clade B Env, JRFL, membrane bound Indian...

journal_title：Vaccine

authors： Shrivastava T,Samal S,Tyagi AK,Goswami S,Kumar N,Ozorowski G,Ward AB,Chakrabarti BK

更新日期：2018-03-14 00:00:00

abstract：:The presence of foot-and-mouth disease (FMD) in a country is a major obstacle to the development of agriculture because of its adverse effects on livestock production and agricultural exports. The eradication of FMD in sub-saharan Africa by the implementation of slaughtering-out is impractical for various reasons, but...

journal_title：Vaccine

authors： Hunter P

更新日期：1998-01-01 00:00:00

abstract：:The immunogenicity of two meningococcal outer membrane vesicle (OMV) vaccines, namely the Norwegian wild-type OMV vaccine and the Dutch hexavalent PorA OMV vaccine, were examined in infant cynomolgus monkeys. For the first time, a wild-type- and a recombinant OMV vaccine were compared. Furthermore, the induction of me...

journal_title：Vaccine

authors： Rouppe van der Voort E,Schuller M,Holst J,de Vries P,van der Ley P,van den Dobbelsteen G,Poolman J

更新日期：2000-01-31 00:00:00

abstract：:This large study investigates the associations between bovine major histocompatibility complex DRB3 alleles and their binding pockets with the immune response to a 40-mer peptide derived from foot-and-mouth disease virus (FMDV) VP1. A crossbred (Charolais and Holstein) cattle population (n=197) was immunised with the ...

journal_title：Vaccine

authors： Baxter R,Craigmile SC,Haley C,Douglas AJ,Williams JL,Glass EJ

更新日期：2009-12-10 00:00:00

abstract：:Since 2005, the Government of the United States of America has provided more than US$ 50 million to advance influenza vaccine development in low-resourced countries. This programme has provided a unique opportunity for the US Government to develop a comprehensive view of, and to understand better the challenges and fu...

journal_title：Vaccine

authors： Perdue ML,Bright RA

更新日期：2011-07-01 00:00:00

abstract：:Development partners and donors have encouraged and incentivized governments in developing countries to explore ways of working with third-party service suppliers to reduce costs and increase service delivery capacity. The distribution of vaccines and medicines has for a long time shown demand for outsourcing but publ...

journal_title：Vaccine

authors： Wright M,Forster G,Beale J

更新日期：2017-04-19 00:00:00