A population-based study on tetanus antitoxin levels in The Netherlands.

Abstract:

:We assessed the tetanus immunity of the general Dutch population and of religious groups refusing vaccination by means of population-based study to evaluate the effect of tetanus vaccination. More than 95% of those born after the introduction of routine vaccination had tetanus antitoxin levels above the minimum protective level. After the sixth vaccination, a fall in tetanus antitoxin levels occurred. Nevertheless, immunisation in accordance with the routine programme most likely induces protection for much longer than two decades. Not only many members of religious groups who refuse vaccination, but also many adults born before the introduction of vaccination lack tetanus immunity. These cohorts might benefit most from (re)vaccination.

journal_name

Vaccine

journal_title

Vaccine

authors

de Melker HE,van den Hof S,Berbers GA,Nagelkerke NJ,Rümke HC,Conyn-van Spaendonck MA

doi

10.1016/s0264-410x(99)00186-3

subject

Has Abstract

pub_date

1999-08-20 00:00:00

pages

100-8

issue

1-2

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(99)00186-3

journal_volume

18

pub_type

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