Roles for endocytosis in lentiviral replication.

Abstract:

:Endocytosis is essential for the entry of many viruses into cells. The primate lentiviruses [human immunodeficiency virus (HIV) 1 and 2, and the simian immunodeficiency viruses (SIVs)], however, use endocytosis in other aspects of their life cycles. Here, the authors describe the ways in which the endocytic pathway is used by HIV and SIV and discuss the mechanisms through which endocytosis may contribute to the pathogenic properties of these viruses.

journal_name

Trends Cell Biol

journal_title

Trends in cell biology

authors

Marsh M,Pelchen-Matthews A,Hoxie JA

doi

10.1016/S0962-8924(97)20038-3

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

1-4

issue

1

eissn

0962-8924

issn

1879-3088

pii

S0962-8924(97)20038-3

journal_volume

7

pub_type

杂志文章
  • Connecting the paths in plant stem cell regulation.

    abstract::Stem cell niches are specialized microenvironments where pluripotent cells are maintained to provide undifferentiated cells for the formation of new tissues and organs. The balance between stem cell maintenance within the niche and differentiation of cells that exit it is regulated by local cell-cell communication, to...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2007.06.002

    authors: Tucker MR,Laux T

    更新日期:2007-08-01 00:00:00

  • Invisible woman?

    abstract::The number of invited women speakers at scientific meetings is much less than their proportion in a field. This means that women have fewer venues to present their research, less opportunity to increase their professional network, and smaller chances of promotion and financial support. The paucity of women speakers al...

    journal_title:Trends in cell biology

    pub_type: 杂志文章

    doi:10.1016/j.tcb.2015.06.001

    authors: Masur SK

    更新日期:2015-08-01 00:00:00

  • Translational environmental biology: cell biology informing conservation.

    abstract::Typically, findings from cell biology have been beneficial for preventing human disease. However, translational applications from cell biology can also be applied to conservation efforts, such as protecting coral reefs. Recent efforts to understand the cell biological mechanisms maintaining coral health such as innate...

    journal_title:Trends in cell biology

    pub_type: 杂志文章

    doi:10.1016/j.tcb.2014.03.001

    authors: Traylor-Knowles N,Palumbi SR

    更新日期:2014-05-01 00:00:00

  • A New Paradigm in Catalase Research.

    abstract::Recent findings provide evidence for dynamic and highly regulated dual subcellular localization of catalase, a hydrogen peroxide (H2O2)-metabolizing enzyme, in peroxisomes and the cytosol. These data suggest a number of important implications for the field of oxidative stress biology. ...

    journal_title:Trends in cell biology

    pub_type: 杂志文章

    doi:10.1016/j.tcb.2020.12.006

    authors: Fujiki Y,Bassik MC

    更新日期:2021-01-06 00:00:00

  • Endoreplication: The Good, the Bad, and the Ugly.

    abstract::To battle adverse internal and external conditions and maintain homeostasis, diploid organisms employ various cellular processes, such as proliferation and apoptosis. In some tissues, an alternative mechanism, endoreplication, is employed toward similar goals. Endoreplication is an evolutionarily conserved cell cycle ...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2018.02.006

    authors: Shu Z,Row S,Deng WM

    更新日期:2018-06-01 00:00:00

  • MHC class II molecules: transport pathways for antigen presentation.

    abstract::During biosynthesis, MHC class II molecules travel through the endocytic pathway and interact with antigenic peptides before their stable insertion in the plasma membrane. The process of class II association with these peptides and their final deposition at the cell surface are essential steps in boosting specific ant...

    journal_title:Trends in cell biology

    pub_type: 杂志文章

    doi:10.1016/S0962-8924(97)01000-3

    authors: Wubbolts R,Fernandez-Bona M,Neefjes J

    更新日期:1997-03-01 00:00:00

  • Complex Cartography: Regulation of E2F Transcription Factors by Cyclin F and Ubiquitin.

    abstract::The E2F family of transcriptional regulators sits at the center of cell cycle gene expression and plays vital roles in normal and cancer cell cycles. Whereas control of E2Fs by the retinoblastoma family of proteins is well established, much less is known about their regulation by ubiquitin pathways. Recent studies pla...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2020.05.002

    authors: Emanuele MJ,Enrico TP,Mouery RD,Wasserman D,Nachum S,Tzur A

    更新日期:2020-08-01 00:00:00

  • Shedding microvesicles: artefacts no more.

    abstract::The small vesicles shed from the surface of many cells upon stimulation, considered for a long time to be artefacts, are now recognized as specific structures that are distinct from the exosomes released upon exocytosis of multivesicular bodies. Recent reports indicate that shedding vesicles participate in important b...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2008.11.003

    authors: Cocucci E,Racchetti G,Meldolesi J

    更新日期:2009-02-01 00:00:00

  • Raf: the holy grail of Ras biology?

    abstract::Ras proteins regulate cell growth and differentiation, and their mutation plays a major, direct role in causing human cancer. For years, their precise function has been a mystery. One of the pathways Ras controls has recently been identified. It consists of a cascade of kinases (Raf, MEK and MAP kinases) that transmit...

    journal_title:Trends in cell biology

    pub_type: 杂志文章

    doi:10.1016/0962-8924(94)90075-2

    authors: McCormick F

    更新日期:1994-10-01 00:00:00

  • Protein Sorting within Chloroplasts.

    abstract::Chloroplasts have multiple suborganellar membranes. Correct and efficient translocation of chloroplast proteins from their site of synthesis into or across membranes to their functional compartments are fundamental processes. In recent years, several new components and regulatory mechanisms involved in chloroplast pro...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2020.09.011

    authors: Xu X,Ouyang M,Lu D,Zheng C,Zhang L

    更新日期:2021-01-01 00:00:00

  • p130Cas: a versatile scaffold in signaling networks.

    abstract::The Cas family of multiadaptor and scaffold molecules has an essential role in intracellular signaling events. Although these proteins do not have enzymatic or transcriptional activity, they spatially and temporally control signaling events through their ability to undergo changes in phosphorylation and to associate w...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2006.03.003

    authors: Defilippi P,Di Stefano P,Cabodi S

    更新日期:2006-05-01 00:00:00

  • Proteostasis impairment in protein-misfolding and -aggregation diseases.

    abstract::Cells possess an extensive network of components to safeguard proteome integrity and maintain protein homeostasis (proteostasis). When this proteostasis network (PN) declines in performance, as may be the case during aging, newly synthesized proteins are no longer able to fold efficiently and metastable proteins lose ...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2014.05.003

    authors: Hipp MS,Park SH,Hartl FU

    更新日期:2014-09-01 00:00:00

  • Role of MINOS in mitochondrial membrane architecture and biogenesis.

    abstract::Mitochondria possess a complex architecture with two membranes. The inner membrane is divided into two domains: the inner boundary membrane, which is adjacent to the outer membrane, and membrane invaginations termed cristae. Both domains are connected by tubular openings, the crista junctions. Recent studies led to th...

    journal_title:Trends in cell biology

    pub_type: 杂志文章

    doi:10.1016/j.tcb.2012.01.004

    authors: van der Laan M,Bohnert M,Wiedemann N,Pfanner N

    更新日期:2012-04-01 00:00:00

  • FH proteins as cytoskeletal organizers.

    abstract::Regulation of cell shape is a poorly understood yet central issue in cell biology. Recent experiments indicate that FH proteins link cellular signalling pathways to changes in cell shape. Members of the FH protein family play essential roles in cytokinesis and in driving alterations in cell polarity. This review discu...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/s0962-8924(97)01217-8

    authors: Wasserman S

    更新日期:1998-03-01 00:00:00

  • Germline cysts: a conserved phase of germ cell development?

    abstract::Germ cells in many vertebrate and invertebrate species initiate gametogenesis by forming groups of interconnected cells known as germline cysts. Recent studies using Xenopus, mouse and Drosophila are beginning to uncover the cellular and molecular mechanisms that control germline cyst formation and, in conjunction wit...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/s0962-8924(99)01594-9

    authors: Pepling ME,de Cuevas M,Spradling AC

    更新日期:1999-07-01 00:00:00

  • Proteins on the move: dynamic protein localization in prokaryotes.

    abstract::Despite their small size and lack of obvious intracellular structures, bacteria have a complex and dynamic intracellular organization. Recent work has shown that many proteins, and even regions of the chromosome, are localized to specific subcellular regions that can change over time, sometimes extraordinarily fast. P...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/s0962-8924(00)01840-7

    authors: Jensen RB,Shapiro L

    更新日期:2000-11-01 00:00:00

  • The Golgi apparatus: 100 years of progress and controversy.

    abstract::Research on the Golgi apparatus has resulted in major advances in understanding its structure and functions, but many important questions remain unanswered. The history of the Golgi apparatus has been marked by arguments and controversies, some of which have been resolved, whereas others are still ongoing. This articl...

    journal_title:Trends in cell biology

    pub_type: 传,历史文章,杂志文章,评审

    doi:10.1016/s0962-8924(97)01187-2

    authors: Farquhar MG,Palade GE

    更新日期:1998-01-01 00:00:00

  • Inflammatory cells during wound repair: the good, the bad and the ugly.

    abstract::Damage to any tissue triggers a cascade of events that leads to rapid repair of the wound - if the tissue is skin, then repair involves re-epithelialization, formation of granulation tissue and contraction of underlying wound connective tissues. This concerted effort by the wounded cell layers is accompanied by, and m...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2005.09.002

    authors: Martin P,Leibovich SJ

    更新日期:2005-11-01 00:00:00

  • JAKs and STATs branch out.

    abstract::The JAK-STAT signal-transduction pathway is utilized by a wide range of cytokines to regulate gene expression. Cytokines activate members of the JAK family o f protein tyrosine kinases, which in turn activate, by tyrosine phosphorylation, one or more STAT transcription factor family members. Activated STATs form dimer...

    journal_title:Trends in cell biology

    pub_type: 杂志文章

    doi:10.1016/0962-8924(96)10028-3

    authors: Briscoe J,Kohlhuber F,Müller M

    更新日期:1996-09-01 00:00:00

  • Iron uptake and metabolism in the new millennium.

    abstract::Iron is an essential element for metabolic processes intrinsic to life, and yet the properties that make iron a necessity also make it potentially deleterious. To avoid harm, iron homeostasis is achieved through iron transport, storage and regulatory proteins. The functions of some of these molecules are well describe...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2006.12.003

    authors: Dunn LL,Suryo Rahmanto Y,Richardson DR

    更新日期:2007-02-01 00:00:00

  • Cristae Membrane Dynamics - A Paradigm Change.

    abstract::Mitochondria are dynamic organelles that have essential metabolic and regulatory functions. Earlier studies using electron microscopy (EM) revealed an immense diversity in the architecture of cristae - infoldings of the mitochondrial inner membrane (IM) - in different cells, tissues, bioenergetic and metabolic conditi...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2020.08.008

    authors: Kondadi AK,Anand R,Reichert AS

    更新日期:2020-12-01 00:00:00

  • Protein quality control gets muscle into shape.

    abstract::The synthesis, assembly and organisation of structural and motor proteins during muscle formation requires temporal and spatial control directed by specialized chaperones. For example, alphaB-crystallin, GimC and TRiC facilitate the assembly of sarcomeric proteins such as desmin and actin. Recent studies have demonstr...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2008.03.007

    authors: Kim J,Löwe T,Hoppe T

    更新日期:2008-06-01 00:00:00

  • ErbB receptors: new insights on mechanisms and biology.

    abstract::The ErbB family of four receptor tyrosine kinases occupies a central role in a wide variety of biological processes from neuronal development to breast cancer. New information continues to expand their biologic significance and to unravel the molecular mechanisms that underlie the signaling capacity of these receptors...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2006.10.008

    authors: Linggi B,Carpenter G

    更新日期:2006-12-01 00:00:00

  • Golgi disassembly in apoptosis: cause or effect?

    abstract::The Golgi complex undergoes a dramatic disassembly process during apoptosis. Some Golgi proteins implicated in Golgi structure and vesicle transport are cleaved during apoptosis, and expression of noncleavable mutants of these proteins delays Golgi disassembly after pro-apoptotic stimuli. Cleavage of Golgi structural ...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/s0962-8924(03)00101-6

    authors: Machamer CE

    更新日期:2003-06-01 00:00:00

  • Regulation and control of myosin-I by the motor and light chain-binding domains.

    abstract::Members of the myosin-I family of molecular motors are expressed in many eukaryotes, where they are involved in a multitude of critical processes. Humans express eight distinct members of the myosin-I family, making it the second largest family of myosins expressed in humans. Despite the high degree of sequence conser...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2012.10.008

    authors: Greenberg MJ,Ostap EM

    更新日期:2013-02-01 00:00:00

  • Understanding Ubiquinone.

    abstract::Ubiquinone (UQ; also known as coenzyme Q; CoQ) is a mobile component of the mitochondrial electron transport chain, where it acts as a pro-oxidant in its ubisemiquinone state. Despite this, UQ is also believed to be a membrane antioxidant. These properties place UQ at the center of hotly debated questions about how mi...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2015.12.007

    authors: Wang Y,Hekimi S

    更新日期:2016-05-01 00:00:00

  • Pathways for membrane trafficking during cytokinesis.

    abstract::The molecular mechanisms underlying targeted deposition of new membrane at the advancing furrow of a dividing cell have long been intriguing to cell biologists. Three recent studies have made use of Drosophila cellularization to explore current questions in this field. These findings indicate that both the secretory p...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2004.01.006

    authors: Strickland LI,Burgess DR

    更新日期:2004-03-01 00:00:00

  • Interface between Physics and Biology: Training a New Generation of Creative Bilingual Scientists.

    abstract::Whereas physics seeks for universal laws underlying natural phenomena, biology accounts for complexity and specificity of molecular details. Contemporary biological physics requires people capable of working at this interface. New programs prepare scientists who transform respective disciplinary views into innovative ...

    journal_title:Trends in cell biology

    pub_type: 杂志文章

    doi:10.1016/j.tcb.2017.05.002

    authors: Riveline D,Kruse K

    更新日期:2017-08-01 00:00:00

  • Actin coats and rings promote regulated exocytosis.

    abstract::It is well known that actin can associate with intracellular membranes to drive endocytosis and the rocketing motion of bacteria, virions and some organelles and to regulate synaptic vesicle plasticity. Actin also has been extensively reported to be involved at several steps of exocytosis; however, it has typically be...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2012.03.003

    authors: Nightingale TD,Cutler DF,Cramer LP

    更新日期:2012-06-01 00:00:00

  • Mitochondrial dynamics in neurodegeneration.

    abstract::It has been only 15 years since studies began on the molecular mechanisms underlying mitochondrial fission and fusion using simple model organisms such as Drosophila, yeast, and Caenorhabditis elegans. Beyond the primary functions of mitochondrial fission and fusion in controlling organelle shape, size, and number, it...

    journal_title:Trends in cell biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.tcb.2012.10.006

    authors: Itoh K,Nakamura K,Iijima M,Sesaki H

    更新日期:2013-02-01 00:00:00